Begoña Diaz

Summary

Publications

  1. pmc Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia
    Begoña Diaz
    Cancer Center, Tumor Microenvironment Program, Sanford Burnham Medical Research Institute, La Jolla, CA 92037, USA
    J Cell Biol 201:279-92. 2013
  2. pmc Redox signaling at invasive microdomains in cancer cells
    Begoña Diaz
    Cancer Center, Sanford Burnham Medical Research Institute, La Jolla, CA 92037, USA
    Free Radic Biol Med 52:247-56. 2012
  3. pmc Genetic disruption of the sh3pxd2a gene reveals an essential role in mouse development and the existence of a novel isoform of tks5
    Pilar Cejudo-Martin
    Cancer Center, Tumor Microenvironment and Metastasis Program, Sanford Burnham Medical Research Institute, La Jolla, California, United States of America
    PLoS ONE 9:e107674. 2014
  4. pmc The invadopodia scaffold protein tks5 is required for the growth of human breast cancer cells in vitro and in vivo
    Barbara Blouw
    Tumor Microenvironment and Metastasis Program, NCI Cancer Center, Sanford Burnham Medical Research Institute, La Jolla, California, United States of America
    PLoS ONE 10:e0121003. 2015
  5. pmc Novel p47(phox)-related organizers regulate localized NADPH oxidase 1 (Nox1) activity
    Davide Gianni
    Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA 92037, USA
    Sci Signal 2:ra54. 2009
  6. pmc A Src-Tks5 pathway is required for neural crest cell migration during embryonic development
    Danielle A Murphy
    Sanford Burnham Medical Research Institute, La Jolla, California, United States of America
    PLoS ONE 6:e22499. 2011

Collaborators

Detail Information

Publications6

  1. pmc Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia
    Begoña Diaz
    Cancer Center, Tumor Microenvironment Program, Sanford Burnham Medical Research Institute, La Jolla, CA 92037, USA
    J Cell Biol 201:279-92. 2013
    ..This signaling pathway might regulate the coordinated acquisition of invasiveness by neighboring cells and mediate the communication between normoxic and hypoxic areas of tumors to facilitate cancer cell invasion...
  2. pmc Redox signaling at invasive microdomains in cancer cells
    Begoña Diaz
    Cancer Center, Sanford Burnham Medical Research Institute, La Jolla, CA 92037, USA
    Free Radic Biol Med 52:247-56. 2012
    ..We focus on redox signaling events mediated by invadopodia NADPH oxidase complexes and their contribution to cancer cell invasion...
  3. pmc Genetic disruption of the sh3pxd2a gene reveals an essential role in mouse development and the existence of a novel isoform of tks5
    Pilar Cejudo-Martin
    Cancer Center, Tumor Microenvironment and Metastasis Program, Sanford Burnham Medical Research Institute, La Jolla, California, United States of America
    PLoS ONE 9:e107674. 2014
    ..Together, these findings indicate the essentiality of the larger Tks5 isoform for correct mammalian development and the transcriptional complexity of the sh3pxd2a gene. ..
  4. pmc The invadopodia scaffold protein tks5 is required for the growth of human breast cancer cells in vitro and in vivo
    Barbara Blouw
    Tumor Microenvironment and Metastasis Program, NCI Cancer Center, Sanford Burnham Medical Research Institute, La Jolla, California, United States of America
    PLoS ONE 10:e0121003. 2015
    ..Together, this work establishes an important role for Tks5 in tumor growth in vivo, and suggests that invadopodia may play broad roles in tumor progression. ..
  5. pmc Novel p47(phox)-related organizers regulate localized NADPH oxidase 1 (Nox1) activity
    Davide Gianni
    Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA 92037, USA
    Sci Signal 2:ra54. 2009
    ..We propose that Tks organizers represent previously unrecognized members of an organizer superfamily that link Nox to localized ROS formation...
  6. pmc A Src-Tks5 pathway is required for neural crest cell migration during embryonic development
    Danielle A Murphy
    Sanford Burnham Medical Research Institute, La Jolla, California, United States of America
    PLoS ONE 6:e22499. 2011
    ....