The Application of Minimally Invasive Surgical Techniques. Part II: Total Knee ArthroplastyDerek F Amanatullah
Resident, Department of Orthopaedic Surgery, University of California Davis Health System, Sacramento, California
Am J Orthop (Belle Mead NJ) 41:E140-4. 2012
..Skeptics claim that there is no advantage in using MIS over time-tested approaches and are concerned that MIS approaches are being implemented before being properly subjected to peer review...
- The application of minimally invasive surgical techniques. Part I: total hip arthroplasty
Derek F Amanatullah
Resident, Department of Orthopaedic Surgery, University of California Davis Health System, Sacramento, California
Am J Orthop (Belle Mead NJ) 41:E134-9. 2012
..Skeptics claim that there is no advantage in using MIS over time-tested approaches and are concerned that MIS approaches are being implemented before being properly subjected to peer review...
- Regional gene therapy for full-thickness articular cartilage lesions using naked DNA with a collagen matrix
Paul E Di Cesare
Musculoskeletal Research Laboratory, New York University Hospital for Joint Diseases, Department of Orthopaedic Surgery, 301 East 17th Street, Suite 1500, New York 10003, USA
J Orthop Res 24:1118-27. 2006
..Naked plasmid DNA as a vehicle for transferring therapeutic genes has been shown to be effective in a therapeutic model within rabbit articular cartilage and appears to be safe and cost effective...
- Serum interleukin-6 as a marker of periprosthetic infection following total hip and knee arthroplasty
Paul E Di Cesare
Musculoskeletal Research Center, Room 1500, NYU Hospital for Joint Diseases, 301 East 17th Street, New York, NY 10003, USA
J Bone Joint Surg Am 87:1921-7. 2005
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- Expression of cartilage oligomeric matrix protein by human synovium
P E Di Cesare
Musculoskeletal Research Center, Hospital for Joint Diseases Orthopaedic Institute, New York, NY 10003, USA
FEBS Lett 412:249-52. 1997
..Human synovium should be considered as a potential tissue source of COMP in any investigation of biological markers of cartilage metabolism...
- Localization and expression of cartilage oligomeric matrix protein by human rheumatoid and osteoarthritic synovium and cartilage
P E Di Cesare
Musculoskeletal Research Center, Department of Orthopaedic Surgery, New York University Medical Center Hospital for Joint Diseases, New York 10003, USA
J Orthop Res 17:437-45. 1999
..The upregulated expression of cartilage oligomeric matrix protein in inflammatory tissues suggests its in vivo regulation by cytokines...
- Up-regulation of inducible nitric oxide synthase and production of nitric oxide by the Swarm rat and human chondrosarcoma
P E Di Cesare
Department of Orthopaedic Surgery, Musculoskeletal Research Center, New York University Medical Center, Hospital for Joint Diseases Orthopaedic Institute, New York 10003, USA
J Orthop Res 16:667-74. 1998
..Because the chondrosarcoma of the Swarm rat is a well differentiated solid tumor that rarely metastasizes, nitric oxide may be produced by the tumor to promote local growth by effects on vascular supply...
- Expression of cartilage oligomeric matrix protein (COMP) by embryonic and adult osteoblasts
P E Di Cesare
Musculoskeletal Research Center, Hospital for Joint Diseases Orthopaedic Institute, New York, New York 10003, USA
J Orthop Res 18:713-20. 2000
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- Matrix-matrix interaction of cartilage oligomeric matrix protein and fibronectin
Paul E Di Cesare
Musculoskeletal Research Center, NYU Hospital for Joint Diseases Department of Orthopedic Surgery, 301 East 17th Street, New York, NY 10030, USA
Matrix Biol 21:461-70. 2002
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ADAMTS-7: a metalloproteinase that directly binds to and degrades cartilage oligomeric matrix proteinChuan Ju Liu
Musculoskeletal Research Center, New York University Hospital for Joint Diseases Department of Orthopaedic Surgery, School of Medicine, 301 East 17th St, New York, New York 10003, USA
FASEB J 20:988-90. 2006
..ADAMTS-7 is the first metalloproteinase found to bind directly to and degrade COMP...
- Expression of bone morphogenetic proteins, receptors, and tissue inhibitors in human fetal, adult, and osteoarthritic articular cartilage
Andrew L Chen
Department of Orthopaedic Surgery, Musculoskeletal Research Center, NYU Hospital for Joint Diseases Orthopaedic Institute, 301 East 17th Street, New York, NY 1003, USA
J Orthop Res 22:1188-92. 2004
..Similarly, Western blotting demonstrated BMPs 7 and 8 to be present in fetal but not in adult samples. BMP-3 protein was present in fetal and adult normal samples, to a lesser extent, but absent in osteoarthritic cartilage...
- Cartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferation
Ke Xu
Department of Orthopaedic Surgery, New York University Hospital for Joint Diseases, New York, New York 10003, USA
J Biol Chem 282:11347-55. 2007
..These findings provide the first evidence linking the association of COMP and GEP and identifying a previously unrecognized growth factor (i.e. GEP) in cartilage...
- A silencer element in the cartilage oligomeric matrix protein gene regulates chondrocyte-specific expression
Paul S Issack
Department of Orthopaedic Surgery, Musculoskeletal Research Center, Hospital for Joint Diseases, NYU, 301 East 17th Street, New York, NY, USA
J Orthop Res 22:751-8. 2004
..These results suggest that negative regulation of transcription is an important mechanism for chondrocyte-specific expression of the COMP gene...
- Doublecortin is expressed in articular chondrocytes
Yi Zhang
Lawrence Ellison Center for Tissue Regeneration and Repair, Department of Orthopaedic Surgery, School of Medicine, University of California Davis, 4635 Second Avenue, Room 2000, Sacramento, CA 95817, USA
Biochem Biophys Res Commun 363:694-700. 2007
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- The interferon-inducible p204 protein acts as a transcriptional coactivator of Cbfa1 and enhances osteoblast differentiation
Chuan Ju Liu
Musculoskeletal Research Center and Department of Orthopaedic Surgery, New York University, Hospital for Joint Diseases, New York, New York 10003, USA
J Biol Chem 280:2788-96. 2005
..p204, which is the first interferon-inducible protein found to associate with Cbfa1, functions as a novel regulator of osteoblast differentiation...
- The retinoblastoma protein is an essential mediator of osteogenesis that links the p204 protein to the Cbfa1 transcription factor thereby increasing its activity
Yi Luan
Department of Orthopedic Surgery, New York University Medical Center, New York, New York 10003, USA
J Biol Chem 282:16860-70. 2007
..Furthermore, as revealed in reporter gene and in vitro osteogenesis assays p204 synergized with pRb in the stimulation of Cbfa1-dependent gene activation and osteoblast differentiation...
- Transcriptional activation of cartilage oligomeric matrix protein by Sox9, Sox5, and Sox6 transcription factors and CBP/p300 coactivators
Chuan Ju Liu
Department of Orthopaedic Surgery, NYU Hospital for Joint Diseases, New York, NY 10003, USA
Front Biosci 12:3899-910. 2007
..This study provides the first evidence that Sox9 directly associates with COMP gene promoter and that mediation of COMP gene activation by Sox9 involves Sox5, Sox6, CBP, and p300 coactivators...
- Antibiotic susceptibility of bacteria infecting total joint arthroplasty sites
Eric Fulkerson
Musculoskeletal Research Center, New York University Hospital for Joint Diseases, 301 East 17th Street, New York, NY 10003, USA
J Bone Joint Surg Am 88:1231-7. 2006
..Furthermore, we believe that if culture results and other confirmatory tests are not positive by the fourth postoperative day, termination of empiric antibiotic therapy should be considered...
- ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein
Chuan Ju Liu
Department of Orthopaedic Surgery, Musculoskeletal Research Center, New York University Hospital for Joint Diseases, New York, New York 10003, USA
J Biol Chem 281:15800-8. 2006
..Together, these findings indicate that ADAMTS-12 is a new COMP-interacting and -degrading enzyme and thus may play an important role in the COMP degradation in the initiation and progression of arthritis...
- Osteotomy about the knee: applications, techniques, and results
Charles F Preston
Department of Orthopedic Surgery, NYU-Hospital for Joint Diseases, New York, NY 10003, USA
J Knee Surg 18:258-72. 2005
..Recent long-term follow-up studies have concluded osteotomy allows for improved function and pain relief in properly selected young patients...
- Expression of bone morphogenetic proteins by Dupuytren's fibroblasts
Steven S Shin
Musculoskeletal Research Center, Department of Orthopaedic Surgery, NYU-Hospital for Joint Diseases, New York, NY 10003, USA
J Hand Surg [Am] 29:809-14. 2004
..Whether BMP-4 is necessary and/or sufficient for maintaining a normal palmar fascia fibroblast phenotype is not yet known. Further studies are needed to elucidate the exact role of BMPs, and especially BMP-4, in Dupuytren's fibroblasts...
- Leukemia/lymphoma-related factor, a POZ domain-containing transcriptional repressor, interacts with histone deacetylase-1 and inhibits cartilage oligomeric matrix protein gene expression and chondrogenesis
Chuan Ju Liu
Musculoskeletal Research Center, New York University Hospital for Joint Diseases Department of Orthopedic Surgery, New York, New York 10003, USA
J Biol Chem 279:47081-91. 2004
..LRF is the first transcription factor found to bind directly to the COMP gene promoter, to recruit HDAC1, and to regulate both COMP gene expression and chondrogenic differentiation...
- Scaffolds for articular cartilage repair
Sally R Frenkel
NYU Hospital for Joint Diseases, Musculoskeletal Research Center, Department of Orthopaedic Surgery, New York, NY 10003, USA
Ann Biomed Eng 32:26-34. 2004
..This review will discuss various promising scaffolds for cartilage tissue engineering applications...
- Cartilage oligomeric matrix protein expression in hepatocellular carcinoma and the cirrhotic liver
Yi Xiao
Department of General Surgery, University of Heidelberg, Heidelberg, Germany
J Gastroenterol Hepatol 19:296-302. 2004
..CONCLUSION: COMP is highly expressed within the tumor cells of HCC, suggesting that COMP might play a role in the pathophysiology of this disease...
- Use of antibiotic-impregnated cement in total joint arthroplasty
Thomas N Joseph
Department of Orthopaedic Surgery, Musculoskeletal Research Center, NYU-Hospital for Joint Diseases, New York, NY, USA
J Am Acad Orthop Surg 11:38-47. 2003
..Problems associated with antibiotic-impregnated cement in total joint arthroplasty include weakening of the cement and the generation of antibiotic-resistant bacteria in infected implant sites...
- Clinical applications of growth factors for articular cartilage repair
Derrick G Hickey
Department of Orthopaedic Surgery, New York University Medical Center-Hospital for Joint Diseases, New York, New York, USA
Am J Orthop 32:70-6. 2003
..Orthopedic surgeons need to be familiar with the properties of these growth factors, as they hold great therapeutic promise. In-progress clinical studies are examining how growth factors may have applications in treatments of bone...
