SEAN CL DEONI

Summary

Publications

  1. ncbi request reprint Rapid combined T1 and T2 mapping using gradient recalled acquisition in the steady state
    Sean C L Deoni
    Imaging Research Laboratories, Robarts Research Institute, London, Ontario, Canada
    Magn Reson Med 49:515-26. 2003
  2. ncbi request reprint High-resolution T1 mapping of the brain at 3T with driven equilibrium single pulse observation of T1 with high-speed incorporation of RF field inhomogeneities (DESPOT1-HIFI)
    Sean C L Deoni
    Centre for Neuroimaging Research, Institute of Psychiatry, King s College London, London UK
    J Magn Reson Imaging 26:1106-11. 2007
  3. pmc One component? Two components? Three? The effect of including a nonexchanging "free" water component in multicomponent driven equilibrium single pulse observation of T1 and T2
    Sean C L Deoni
    Advanced Baby Imaging Lab, School of Engineering, Brown University, Providence, Rhode Island 02912, USA
    Magn Reson Med 70:147-54. 2013
  4. pmc Investigating white matter development in infancy and early childhood using myelin water faction and relaxation time mapping
    Sean C L Deoni
    Advanced Baby Imaging Lab, School of Engineering, Brown University, Providence, RI, USA
    Neuroimage 63:1038-53. 2012
  5. pmc Correction of main and transmit magnetic field (B0 and B1) inhomogeneity effects in multicomponent-driven equilibrium single-pulse observation of T1 and T2
    Sean C L Deoni
    Centre for Neuroimaging Research, Institute of Psychiatry, King s College London, London, United Kingdom
    Magn Reson Med 65:1021-35. 2011
  6. doi request reprint Mapping infant brain myelination with magnetic resonance imaging
    Sean C L Deoni
    Centre for Neuroimaging Sciences, Institute of Psychiatry, London SE5 8AF, UK
    J Neurosci 31:784-91. 2011
  7. doi request reprint Transverse relaxation time (T2) mapping in the brain with off-resonance correction using phase-cycled steady-state free precession imaging
    Sean C L Deoni
    Centre for Neuroimaging Research, Institute of Psychiatry, King s College London, London, UK
    J Magn Reson Imaging 30:411-7. 2009
  8. doi request reprint Gleaning multicomponent T1 and T2 information from steady-state imaging data
    Sean C L Deoni
    Centre for Neuroimaging Research, Institute of Psychiatry, King s College London, London UK
    Magn Reson Med 60:1372-87. 2008
  9. doi request reprint Investigating exchange and multicomponent relaxation in fully-balanced steady-state free precession imaging
    Sean C L Deoni
    Centre for Neuroimaging Research, Institute of Psychiatry, King s College London, London, UK
    J Magn Reson Imaging 27:1421-9. 2008
  10. doi request reprint Standardized structural magnetic resonance imaging in multicentre studies using quantitative T1 and T2 imaging at 1.5 T
    Sean C L Deoni
    Centre for Neuroimaging Research, Institute of Psychiatry, King s College London, London, UK
    Neuroimage 40:662-71. 2008

Detail Information

Publications20

  1. ncbi request reprint Rapid combined T1 and T2 mapping using gradient recalled acquisition in the steady state
    Sean C L Deoni
    Imaging Research Laboratories, Robarts Research Institute, London, Ontario, Canada
    Magn Reson Med 49:515-26. 2003
    ..The method therefore permits real-time clinical acquisition and display of whole brain T(1) and T(2) maps for the first time...
  2. ncbi request reprint High-resolution T1 mapping of the brain at 3T with driven equilibrium single pulse observation of T1 with high-speed incorporation of RF field inhomogeneities (DESPOT1-HIFI)
    Sean C L Deoni
    Centre for Neuroimaging Research, Institute of Psychiatry, King s College London, London UK
    J Magn Reson Imaging 26:1106-11. 2007
    ..To investigate an alternative approach to correct for flip angle inaccuracies in the driven equilibrium single pulse observation of T1 (DESPOT1) T1 mapping method...
  3. pmc One component? Two components? Three? The effect of including a nonexchanging "free" water component in multicomponent driven equilibrium single pulse observation of T1 and T2
    Sean C L Deoni
    Advanced Baby Imaging Lab, School of Engineering, Brown University, Providence, Rhode Island 02912, USA
    Magn Reson Med 70:147-54. 2013
    ..It is concluded that this model is preferable for future studies and analysis...
  4. pmc Investigating white matter development in infancy and early childhood using myelin water faction and relaxation time mapping
    Sean C L Deoni
    Advanced Baby Imaging Lab, School of Engineering, Brown University, Providence, RI, USA
    Neuroimage 63:1038-53. 2012
    ..Comparison of T(1), T(2) and MWF measurements demonstrates dissimilar sensitivity to tissue changes associated with neurodevelopment, with each providing differential but complementary information...
  5. pmc Correction of main and transmit magnetic field (B0 and B1) inhomogeneity effects in multicomponent-driven equilibrium single-pulse observation of T1 and T2
    Sean C L Deoni
    Centre for Neuroimaging Research, Institute of Psychiatry, King s College London, London, United Kingdom
    Magn Reson Med 65:1021-35. 2011
    ..The approach was also successfully demonstrated in vivo, with near artifact-free whole-brain, high spatial resolution (1.7 mm × 1.7 mm × 1.7 mm isotropic voxels) myelin water fraction maps acquired in a clinically feasible 16 min...
  6. doi request reprint Mapping infant brain myelination with magnetic resonance imaging
    Sean C L Deoni
    Centre for Neuroimaging Sciences, Institute of Psychiatry, London SE5 8AF, UK
    J Neurosci 31:784-91. 2011
    ..This work represents a significant step forward in our ability to appreciate the fundamental process of myelination, and provides the first ever in vivo visualization of myelin maturation in healthy human infancy...
  7. doi request reprint Transverse relaxation time (T2) mapping in the brain with off-resonance correction using phase-cycled steady-state free precession imaging
    Sean C L Deoni
    Centre for Neuroimaging Research, Institute of Psychiatry, King s College London, London, UK
    J Magn Reson Imaging 30:411-7. 2009
    ..To investigate a new approach for more completely accounting for off-resonance affects in the DESPOT2 (driven equilibrium single pulse observation of T(2)) mapping technique...
  8. doi request reprint Gleaning multicomponent T1 and T2 information from steady-state imaging data
    Sean C L Deoni
    Centre for Neuroimaging Research, Institute of Psychiatry, King s College London, London UK
    Magn Reson Med 60:1372-87. 2008
    ....
  9. doi request reprint Investigating exchange and multicomponent relaxation in fully-balanced steady-state free precession imaging
    Sean C L Deoni
    Centre for Neuroimaging Research, Institute of Psychiatry, King s College London, London, UK
    J Magn Reson Imaging 27:1421-9. 2008
    ..In many biological tissues (such as white and gray matter), it is well established that the T(2) decay curve is more accurately described by the summation of more than one relaxation species...
  10. doi request reprint Standardized structural magnetic resonance imaging in multicentre studies using quantitative T1 and T2 imaging at 1.5 T
    Sean C L Deoni
    Centre for Neuroimaging Research, Institute of Psychiatry, King s College London, London, UK
    Neuroimage 40:662-71. 2008
    ....
  11. ncbi request reprint Visualization of the deep cerebellar nuclei using quantitative T1 and rho magnetic resonance imaging at 3 Tesla
    Sean C L Deoni
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, Oxford, and Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, London, UK
    Neuroimage 37:1260-6. 2007
    ..The application of this technique to disorders with cerebellar dysfunction could provide new insight into pathologies like autism and movement disorders...
  12. ncbi request reprint Investigating the effect of exchange and multicomponent T(1) relaxation on the short repetition time spoiled steady-state signal and the DESPOT1 T(1) quantification method
    Sean C L Deoni
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, London, UK
    J Magn Reson Imaging 25:570-8. 2007
    ..To examine the spoiled steady-state (spoiled gradient-recalled echo sequence [SPGR]) signal arising from two-compartment systems and the role of experimental parameters, in particular TR for resolving signal from each compartment...
  13. doi request reprint High resolution diffusion-weighted imaging in fixed human brain using diffusion-weighted steady state free precession
    Jennifer A McNab
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, University of Oxford, Oxford, UK
    Neuroimage 46:775-85. 2009
    ....
  14. ncbi request reprint Synthetic T1-weighted brain image generation with incorporated coil intensity correction using DESPOT1
    Sean C L Deoni
    Centre for Neuroimaging Sciences, Institute of Psychiatry, Box P089, London SE5 8AF, UK
    Magn Reson Imaging 24:1241-8. 2006
    ..This technique also provides a robust method for signal normalization, which is useful in multicenter longitudinal MR studies of disease progression, and allows the user to reconstruct T(1)-weighted images with arbitrary T(1) weighting...
  15. ncbi request reprint Segmentation of thalamic nuclei using a modified k-means clustering algorithm and high-resolution quantitative magnetic resonance imaging at 1.5 T
    Sean C L Deoni
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, PO89, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
    Neuroimage 34:117-26. 2007
    ....
  16. ncbi request reprint Determination of optimal angles for variable nutation proton magnetic spin-lattice, T1, and spin-spin, T2, relaxation times measurement
    Sean C L Deoni
    Imaging Research Laboratories, Robarts Research Institute, London, Ontario, Canada
    Magn Reson Med 51:194-9. 2004
    ..This new approach, suited for imaging applications where large T1 and T2 ranges are anticipated, provides high and uniform precision over a wide range of T1 and T2 values...
  17. ncbi request reprint Quantitative diffusion imaging with steady-state free precession
    Sean C L Deoni
    Imaging Research Laboratories, Robarts Research Institute, London, Ontario, Canada
    Magn Reson Med 51:428-33. 2004
    ..Error within the DESPOD-derived ADC maps was found to be less than 3%, with good precision over a biologically relevant range of ADC values...
  18. ncbi request reprint Visualization of thalamic nuclei on high resolution, multi-averaged T1 and T2 maps acquired at 1.5 T
    Sean C L Deoni
    Imaging Research Laboratories, Robarts Research Institute, London, Ontario, Canada
    Hum Brain Mapp 25:353-9. 2005
    ..These results confirm our hypothesis and demonstrate the potential high-resolution quantitative imaging for nucleus visualization and surgical planning...
  19. ncbi request reprint Rapid T2 estimation with phase-cycled variable nutation steady-state free precession
    Sean C L Deoni
    Imaging Research Laboratories, Robarts Research Institute, London, Ontario, Canada
    Magn Reson Med 52:435-9. 2004
    ..The method is demonstrated in vivo with the acquisition of a 0.34 mm3 isotropic resolution T2 map of the brain with high precision and accuracy and significantly reduced artifact...
  20. ncbi request reprint High-resolution T1 and T2 mapping of the brain in a clinically acceptable time with DESPOT1 and DESPOT2
    Sean C L Deoni
    Imaging Research Laboratories, Robarts Research Institute, 100 Perth Drive, London, Ontario, Canada N6A 5K8
    Magn Reson Med 53:237-41. 2005
    ..7 ms and 6.7 ms. These results demonstrate the clinical feasibility of the methods in the study of neurologic disease...