Federico L Dente

Summary

Publications

  1. ncbi Natural exposure to pollen reduces the threshold but does not change the pattern of response to the allergen in allergic subjects
    F L Dente
    Cardio Thoracic Department, University of Pisa, Italy
    Respir Med 94:1073-8. 2000
  2. ncbi Profiles of proinflammatory cytokines in sputum from different groups of severe asthmatic patients
    Federico L Dente
    Pulmonary Unit, Cardio Thoracic Department, University of Pisa, Italy
    Ann Allergy Asthma Immunol 97:312-20. 2006
  3. doi Magnitude of late asthmatic response to allergen in relation to baseline and allergen-induced sputum eosinophilia in mild asthmatic patients
    Federico L Dente
    Cardio Thoracic Department, Respiratory Pathophysiology, University Hospital of Pisa, Pisa, Italy
    Ann Allergy Asthma Immunol 100:457-62. 2008
  4. doi Effects of oral prednisone on sputum eosinophils and cytokines in patients with severe refractory asthma
    Federico L Dente
    Cardiothoracic and Vascular Department, University of Pisa, Pisa, Italy
    Ann Allergy Asthma Immunol 104:464-70. 2010
  5. doi Baseline airway inflammation may be a determinant of the response to ozone exposure in asthmatic patients
    Maria Laura Bartoli
    Cardio Thoracic and Vascular Department, University of Pisa, Pisa, Italy
    Inhal Toxicol 25:127-33. 2013
  6. ncbi Analysis of sputum cell counts during spontaneous moderate exacerbations of asthma in comparison to the stable phase
    Antonella Di Franco
    Cardiothoracic Department, University of Pisa, Pisa, Italy
    J Asthma 40:155-62. 2003
  7. doi Transient sputum eosinophilia may occur over time in non-eosinophilic asthma and this is not prevented by salmeterol
    Elena Bacci
    Cardiothoracic and Vascular Department, Pneumology Section, University of Pisa, Pisa, Italy
    Respirology 17:1199-206. 2012
  8. ncbi Prednisone blunts airway neutrophilic inflammatory response due to ozone exposure in asthmatic subjects
    Barbara Vagaggini
    Pneumology Section, Cardiothoracic Department, University of Pisa, Pisa, Italy
    Respiration 74:61-8. 2007
  9. ncbi Ozone exposure increases eosinophilic airway response induced by previous allergen challenge
    Barbara Vagaggini
    Cardiothoracic Department, Respiratory Pathophysiology Unit, University of Pisa, Pisa, Italy
    Am J Respir Crit Care Med 166:1073-7. 2002
  10. pmc Induced sputum is a reproducible method to assess airway inflammation in asthma
    Elena Bacci
    Cardiothoracic Department, University of Pisa, Italy
    Mediators Inflamm 11:293-8. 2002

Collaborators

Detail Information

Publications14

  1. ncbi Natural exposure to pollen reduces the threshold but does not change the pattern of response to the allergen in allergic subjects
    F L Dente
    Cardio Thoracic Department, University of Pisa, Italy
    Respir Med 94:1073-8. 2000
    ..The natural exposure to pollen induces an increase in bronchial sensitivity to allergen in sensitized subjects, but it does not induce LAR in subjects without LAR outside the pollen season...
  2. ncbi Profiles of proinflammatory cytokines in sputum from different groups of severe asthmatic patients
    Federico L Dente
    Pulmonary Unit, Cardio Thoracic Department, University of Pisa, Italy
    Ann Allergy Asthma Immunol 97:312-20. 2006
    ..Severe asthma represents a heterogeneous group of patients whose characteristics of airway inflammation are poorly known...
  3. doi Magnitude of late asthmatic response to allergen in relation to baseline and allergen-induced sputum eosinophilia in mild asthmatic patients
    Federico L Dente
    Cardio Thoracic Department, Respiratory Pathophysiology, University Hospital of Pisa, Pisa, Italy
    Ann Allergy Asthma Immunol 100:457-62. 2008
    ..Late asthmatic response (LAR) to allergen challenge is a validated method for studying the pathogenesis of and new treatments for asthma in the laboratory...
  4. doi Effects of oral prednisone on sputum eosinophils and cytokines in patients with severe refractory asthma
    Federico L Dente
    Cardiothoracic and Vascular Department, University of Pisa, Pisa, Italy
    Ann Allergy Asthma Immunol 104:464-70. 2010
    ..Severe asthma occurs in a heterogeneous group of patients in whom symptoms and airway inflammation persist despite maximal antiasthma treatment...
  5. doi Baseline airway inflammation may be a determinant of the response to ozone exposure in asthmatic patients
    Maria Laura Bartoli
    Cardio Thoracic and Vascular Department, University of Pisa, Pisa, Italy
    Inhal Toxicol 25:127-33. 2013
    ..It is well known that ozone exposure decreases lung function and increases airway neutrophilia, but large variability has been observed among asthmatic patients...
  6. ncbi Analysis of sputum cell counts during spontaneous moderate exacerbations of asthma in comparison to the stable phase
    Antonella Di Franco
    Cardiothoracic Department, University of Pisa, Pisa, Italy
    J Asthma 40:155-62. 2003
    ..Acute airway inflammation is considered to characterize asthma exacerbations, but its specific cellular pattern has not yet been completely evaluated...
  7. doi Transient sputum eosinophilia may occur over time in non-eosinophilic asthma and this is not prevented by salmeterol
    Elena Bacci
    Cardiothoracic and Vascular Department, Pneumology Section, University of Pisa, Pisa, Italy
    Respirology 17:1199-206. 2012
    ..Symptomatic, steroid-naïve asthmatic patients may have low sputum eosinophil numbers. The aim of the study was to determine whether low sputum eosinophil numbers persisted over time, during treatment with salmeterol monotherapy...
  8. ncbi Prednisone blunts airway neutrophilic inflammatory response due to ozone exposure in asthmatic subjects
    Barbara Vagaggini
    Pneumology Section, Cardiothoracic Department, University of Pisa, Pisa, Italy
    Respiration 74:61-8. 2007
    ..The effect of corticosteroids on the ozone (O3)-induced airway inflammation is still debated...
  9. ncbi Ozone exposure increases eosinophilic airway response induced by previous allergen challenge
    Barbara Vagaggini
    Cardiothoracic Department, Respiratory Pathophysiology Unit, University of Pisa, Pisa, Italy
    Am J Respir Crit Care Med 166:1073-7. 2002
    ..This observation may help explain the synergistic effect of air pollution and allergen exposure in the exacerbation of asthma...
  10. pmc Induced sputum is a reproducible method to assess airway inflammation in asthma
    Elena Bacci
    Cardiothoracic Department, University of Pisa, Italy
    Mediators Inflamm 11:293-8. 2002
    ..We conclude that analysis of induced sputum is a reproducible method to study airway inflammation in asthma. Sample sizes greater than ours give little improvement in the detectable difference of eosinophil percentages...
  11. ncbi Inhaled fluticasone propionate is effective as well as oral prednisone in reducing sputum eosinophilia during exacerbations of asthma which do not require hospitalization
    Antonella Di Franco
    Respiratory Phatophysiology, Cardio Thoracic Department, University of Pisa, Via Paradisa 2, 56214 Pisa, Italy
    Pulm Pharmacol Ther 19:353-60. 2006
    ..We conclude that FP is effective at least as well as P in reducing sputum eosinophilia and in improving airway obstruction due to asthma exacerbation. However, the cost/effectiveness ratio of this option should be further evaluated...
  12. pmc Increase in markers of airway inflammation after ozone exposure can be observed also in stable treated asthmatics with minimal functional response to ozone
    Barbara Vagaggini
    Cardio Thoracic and Vascular Department, University of Pisa, Pisa, Italy
    Respir Res 11:5. 2010
    ..The discrepancy between functional and inflammatory airway response to ozone has been reported in normal subjects, but few data are available for stable asthmatics regularly treated with inhaled corticosteroids...
  13. doi Efficacy of anticholinergic drugs in asthma
    Federica Novelli
    Cardio Thoracic and Vascular Department, University of Pisa, Via Paradisa 2, 56124 Pisa, Italy
    Expert Rev Respir Med 6:309-19. 2012
    ....
  14. ncbi Low sputum eosinophils predict the lack of response to beclomethasone in symptomatic asthmatic patients
    Elena Bacci
    Dipartimento Cardio Toracico, Ospedale di Cisanello, Via Paradisa 2, 56124 Pisa, Italy
    Chest 129:565-72. 2006
    ..The prognostic role of low sputum eosinophils in steroid-naïve, symptomatic asthmatic patients is controversial...