Frank J A Dennissen

Summary

Publications

  1. doi The ubiquitin proteasome system in neurodegenerative diseases: culprit, accomplice or victim?
    F J A Dennissen
    Department of Neuroscience, Faculty of Health Medicine and Life Sciences, Maastricht University, Universiteitssingel 50, P O Box 616, 6200 MD Maastricht, The Netherlands
    Prog Neurobiol 96:190-207. 2012
  2. doi Mutant ubiquitin (UBB+1) associated with neurodegenerative disorders is hydrolyzed by ubiquitin C-terminal hydrolase L3 (UCH-L3)
    Frank J A Dennissen
    Department of Neuroscience, Faculty of Health Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands
    FEBS Lett 585:2568-74. 2011

Detail Information

Publications2

  1. doi The ubiquitin proteasome system in neurodegenerative diseases: culprit, accomplice or victim?
    F J A Dennissen
    Department of Neuroscience, Faculty of Health Medicine and Life Sciences, Maastricht University, Universiteitssingel 50, P O Box 616, 6200 MD Maastricht, The Netherlands
    Prog Neurobiol 96:190-207. 2012
    ..The present paper will focus on critically reviewing the involvement of the UPS in specific neurodegenerative diseases and will discuss if UPS impairment is a cause, a consequence or both of the disease...
  2. doi Mutant ubiquitin (UBB+1) associated with neurodegenerative disorders is hydrolyzed by ubiquitin C-terminal hydrolase L3 (UCH-L3)
    Frank J A Dennissen
    Department of Neuroscience, Faculty of Health Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands
    FEBS Lett 585:2568-74. 2011
    ..We postulate that impaired UCH-L3 function may contribute to the accumulation of full length UBB(+1) in various pathologies...