G Waldemar

Summary

Country: Denmark

Publications

  1. ncbi Access to diagnostic evaluation and treatment for dementia in Europe
    Gunhild Waldemar
    Memory Disorder Research Group, Department of Neurology, Neuroscience Centre, Copenhagen University Hospital Rigshospitalet, Denmark
    Int J Geriatr Psychiatry 22:47-54. 2007
  2. ncbi Cognitive and functional neuroimaging correlate for anosognosia in mild cognitive impairment and Alzheimer's disease
    Asmus Vogel
    Memory Disorders Research Unit, Neuroscience Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Int J Geriatr Psychiatry 20:238-46. 2005
  3. ncbi Recommendations for the diagnosis and management of Alzheimer's disease and other disorders associated with dementia: EFNS guideline
    G Waldemar
    Memory Disorders Research Group, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Denmark
    Eur J Neurol 14:e1-26. 2007
  4. ncbi Clinical significance of corpus callosum atrophy in a mixed elderly population
    C Ryberg
    Danish Research Center for Magnetic Resonance, Copenhagen University Hospital, Hvidovre, Denmark
    Neurobiol Aging 28:955-63. 2007
  5. pmc Efficacy of psychosocial intervention in patients with mild Alzheimer's disease: the multicentre, rater blinded, randomised Danish Alzheimer Intervention Study (DAISY)
    F B Waldorff
    The Memory Disorders Research Group, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, 9 Blegdamsvej, 2100 Copenhagen, Denmark
    BMJ 345:e4693. 2012
  6. doi Corpus callosum atrophy as a predictor of age-related cognitive and motor impairment: a 3-year follow-up of the LADIS study cohort
    C Ryberg
    Memory Disorders Research Group, Department of Neurology, Copenhagen University Hospital, Rigshospitalet Copenhagen, Denmark
    J Neurol Sci 307:100-5. 2011
  7. ncbi Diagnosis and management of Alzheimer's disease and other disorders associated with dementia. The role of neurologists in Europe. European Federation of Neurological Societies
    G Waldemar
    Department of Neurology, Copenhagen University Hospital, Copenhagen, Denmark
    Eur J Neurol 7:133-44. 2000
  8. doi Genetic testing in familial AD and FTD: mutation and phenotype spectrum in a Danish cohort
    S G Lindquist
    Neurogenetics Clinic, Memory Disorders Research Group, Department of Neurology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
    Clin Genet 76:205-9. 2009
  9. doi Over- and under-diagnosis of dementia in ethnic minorities: a nationwide register-based study
    T R Nielsen
    Memory Disorders Research Group, Department of Neurology, Neuroscience Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Int J Geriatr Psychiatry 26:1128-35. 2011
  10. ncbi A novel presenilin 2 mutation (V393M) in early-onset dementia with profound language impairment
    S G Lindquist
    Memory Disorders Research Group, Department of Neurology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
    Eur J Neurol 15:1135-9. 2008

Collaborators

Detail Information

Publications72

  1. ncbi Access to diagnostic evaluation and treatment for dementia in Europe
    Gunhild Waldemar
    Memory Disorder Research Group, Department of Neurology, Neuroscience Centre, Copenhagen University Hospital Rigshospitalet, Denmark
    Int J Geriatr Psychiatry 22:47-54. 2007
    ..Culture-sensitive strategies to promote public knowledge and destigmatize dementia are essential. Policy makers and authorities should be made aware of the benefits of early access to diagnosis and treatment...
  2. ncbi Cognitive and functional neuroimaging correlate for anosognosia in mild cognitive impairment and Alzheimer's disease
    Asmus Vogel
    Memory Disorders Research Unit, Neuroscience Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Int J Geriatr Psychiatry 20:238-46. 2005
    ....
  3. ncbi Recommendations for the diagnosis and management of Alzheimer's disease and other disorders associated with dementia: EFNS guideline
    G Waldemar
    Memory Disorders Research Group, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Denmark
    Eur J Neurol 14:e1-26. 2007
    ..This guideline may contribute to the definition of the role of the specialist physician in providing dementia health care...
  4. ncbi Clinical significance of corpus callosum atrophy in a mixed elderly population
    C Ryberg
    Danish Research Center for Magnetic Resonance, Copenhagen University Hospital, Hvidovre, Denmark
    Neurobiol Aging 28:955-63. 2007
    ..The correlations remained significant after correction for ARWMC grade. In conclusion, CC atrophy was independently associated with impaired global cognitive and motor function in subjects with ARWMC...
  5. pmc Efficacy of psychosocial intervention in patients with mild Alzheimer's disease: the multicentre, rater blinded, randomised Danish Alzheimer Intervention Study (DAISY)
    F B Waldorff
    The Memory Disorders Research Group, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, 9 Blegdamsvej, 2100 Copenhagen, Denmark
    BMJ 345:e4693. 2012
    ..To assess the efficacy at 12 months of an early psychosocial counselling and support programme for outpatients with mild Alzheimer's disease and their primary care givers...
  6. doi Corpus callosum atrophy as a predictor of age-related cognitive and motor impairment: a 3-year follow-up of the LADIS study cohort
    C Ryberg
    Memory Disorders Research Group, Department of Neurology, Copenhagen University Hospital, Rigshospitalet Copenhagen, Denmark
    J Neurol Sci 307:100-5. 2011
    ..In conclusion, CC atrophy, an indicator of reduced functional connectivity between cortical areas, seems to contribute, independently of ARWMC load, to future cognitive and motor decline in the elderly...
  7. ncbi Diagnosis and management of Alzheimer's disease and other disorders associated with dementia. The role of neurologists in Europe. European Federation of Neurological Societies
    G Waldemar
    Department of Neurology, Copenhagen University Hospital, Copenhagen, Denmark
    Eur J Neurol 7:133-44. 2000
    ..The increasing role of neurology in the management of patients with dementia has important implications for training and education...
  8. doi Genetic testing in familial AD and FTD: mutation and phenotype spectrum in a Danish cohort
    S G Lindquist
    Neurogenetics Clinic, Memory Disorders Research Group, Department of Neurology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
    Clin Genet 76:205-9. 2009
    ..Seven presumed pathogenic mutations (two PSEN1, one PSEN2, one APP, one MAPT, and two PGRN) were identified, including a novel PSEN2 mutation (V393M). No dosage aberrations were identified...
  9. doi Over- and under-diagnosis of dementia in ethnic minorities: a nationwide register-based study
    T R Nielsen
    Memory Disorders Research Group, Department of Neurology, Neuroscience Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Int J Geriatr Psychiatry 26:1128-35. 2011
    ..The objective of this study was to compare the prevalence of register-based dementia diagnoses in the largest ethnic minority groups in Denmark with the prevalence of register-based dementia diagnoses in the general Danish population...
  10. ncbi A novel presenilin 2 mutation (V393M) in early-onset dementia with profound language impairment
    S G Lindquist
    Memory Disorders Research Group, Department of Neurology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
    Eur J Neurol 15:1135-9. 2008
    ..Pathogenic mutations in the genes associated with autosomal dominant inherited AD have been shown to alter processing of the amyloid precursor protein (APP) resulting in a relative increase of the amount of Abeta42 peptide...
  11. ncbi Idiopathic normal-pressure hydrocephalus: evaluation and findings in a multidisciplinary memory clinic
    R Bech-Azeddine
    University Clinics of Neurosurgery, Memory Disorders Research Unit, The Neuroscience Centre, Rigshospitalet, Copenhagen, Denmark
    Eur J Neurol 8:601-11. 2001
    ..Evaluating patients with possible INPH in an outpatient multidisciplinary memory clinic is an effective and rational diagnostic approach...
  12. doi Overdiagnosis of dementia in young patients - a nationwide register-based study
    L C Salem
    Memory Disorders Research Group, Danish Dementia Research Center, Department of Neurology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Dement Geriatr Cogn Disord 34:292-9. 2012
    ..The aim of this study was to investigate the validity of the diagnosis of dementia registered in the Danish nationwide hospital registers in young patients...
  13. ncbi Education and training of European neurologists in dementia
    S G Hasselbalch
    Memory Disorders Research Group 6702, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    Eur J Neurol 14:505-9. 2007
    ....
  14. doi The spatial distribution of age-related white matter changes as a function of vascular risk factors--results from the LADIS study
    E Rostrup
    Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Hvidovre, Denmark
    Neuroimage 60:1597-607. 2012
    ..It is concluded that the location of WMH is dependent on the risk factors involved pointing towards a regionally different pathogenesis and/or vulnerability of the white matter...
  15. ncbi The Category Cued Recall test in very mild Alzheimer's disease: discriminative validity and correlation with semantic memory functions
    A Vogel
    Memory Disorders Research Group, Department of Neurology, Neuroscience Centre, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    Eur J Neurol 14:102-8. 2007
    ..This may be because CCR did not tap more semantic processes, which are impaired in the earliest phases of AD, than a test of free recall...
  16. doi Cognitive testing in non-demented Turkish immigrants--comparison of the RUDAS and the MMSE
    T R Nielsen
    Memory Disorders Research Group, Danish Dementia Research Center, Department of Neurology, Neuroscience Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Scand J Psychol 53:455-60. 2012
    ..Although not entirely free of educational bias, the RUDAS can be a valuable supplement to the MMSE for assessment of general cognitive function in Turkish minority populations...
  17. ncbi Reduced 5-HT2A receptor binding in patients with mild cognitive impairment
    S G Hasselbalch
    Neurobiology Research Unit N9201, The Neuroscience Centre, Rigshospitalet, Copenhagen, Denmark
    Neurobiol Aging 29:1830-8. 2008
    ..This may provide some of the pathophysiological background for the neuropsychiatric symptoms found in early AD...
  18. pmc Added Diagnostic Value of (11)C-PiB-PET in Memory Clinic Patients with Uncertain Diagnosis
    K S Frederiksen
    Memory Disorders Research Group, Department of Neurology, Nuclear Medicine and PET, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Dement Geriatr Cogn Dis Extra 2:610-21. 2012
    ..The added diagnostic value of (11)C-PiB-PET for the assessment of the accumulation of cortical beta-amyloid in memory clinic patients with uncertain diagnosis remains undetermined...
  19. doi Alzheimer disease-like clinical phenotype in a family with FTDP-17 caused by a MAPT R406W mutation
    S G Lindquist
    Memory Disorders Research Group, The Neuroscience Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Eur J Neurol 15:377-85. 2008
    ..The clinical and genetic heterogeneity of autosomal dominant inherited dementia must be taken into account in the genetic counselling and genetic testing of families with autosomal dominantly inherited dementia in general...
  20. doi White matter changes contribute to corpus callosum atrophy in the elderly: the LADIS study
    C Ryberg
    Memory Disorders Research Group, Department of Neurology, Copenhagen University Hospital, Copenhagen, Denmark
    AJNR Am J Neuroradiol 29:1498-504. 2008
    ..The aim of this study was to investigate the potential correlation between regional age-related white matter changes (ARWMC) and atrophy of CC in elderly subjects...
  21. ncbi Application of the PredictAD decision support tool to a Danish cohort of patients with Alzheimer's disease and other dementias
    A H Simonsen
    Department of Neurology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
    Dement Geriatr Cogn Disord 37:207-13. 2014
    ..The aim of this project was to investigate the performance of the tool in distinguishing AD from non-AD dementia using a realistic clinical dataset...
  22. ncbi Single photon emission computed tomography and apolipoprotein E in Alzheimer's disease: impact of the epsilon4 allele on regional cerebral blood flow
    P Høgh
    Memory Disorders Research Unit, The Neuroscience Center, Copenhagen University Hospital, Rigshospitalet, Denmark
    J Geriatr Psychiatry Neurol 14:42-51. 2001
    ..The more pronounced reduction of rCBF in frontal association cortex observed in elderly APOE epsilon4-positive patients might predict clinical progression...
  23. doi The Danish Alzheimer intervention study: rationale, study design and baseline characteristics of the cohort
    G Waldemar
    Memory Disorders Research Group, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    Neuroepidemiology 36:52-61. 2011
    ..This paper reports the rationale and design of the Danish Alzheimer Disease Intervention Study and baseline characteristics of the cohort...
  24. pmc Potentially reversible conditions in 1000 consecutive memory clinic patients
    A Hejl
    Memory Disorders Research Unit, Department of Neurology, The Neuroscience Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    J Neurol Neurosurg Psychiatry 73:390-4. 2002
    ..To investigate the prevalence and classification of potentially reversible conditions in a prospective memory clinic cohort of younger and elderly patients with cognitive symptoms...
  25. pmc Idiopathic normal-pressure hydrocephalus: clinical comorbidity correlated with cerebral biopsy findings and outcome of cerebrospinal fluid shunting
    R Bech-Azeddine
    The University Clinic of Neurosurgery, Rigshospitalet, Copenhagen, Denmark
    J Neurol Neurosurg Psychiatry 78:157-61. 2007
    ....
  26. ncbi [Diagnostic imaging in dementia evaluation]
    Steen G Hasselbalch
    H S Rigshospitalet, Neurocentret, H S Hukommelsesklinikken, Arhus Universitetshospital, Arhus Sygehus
    Ugeskr Laeger 168:3415-9. 2006
    ..The aim of the study was to evaluate the changes in diagnoses and treatment by structural scanning in dementia evaluation...
  27. ncbi [Memory problems among elderly patients in general practice: the importance of caregiver information]
    Frans Boch Waldorff
    Københavns Universitet, Center for Sundhed
    Ugeskr Laeger 168:3420-4. 2006
    ..The aim was to describe and analyse signs that make caregivers suspect memory problems among elderly patients in general practice...
  28. ncbi Affective symptoms and cognitive functions in the acute phase of Graves' thyrotoxicosis
    Asmus Vogel
    Memory Disorders Research Group, Department of Neurology, Neuroscience Centre, Copenhagen University Hospital, Rigshospitalet, N6702 9, Blegdamsvej 2100 Copenhagen, Denmark
    Psychoneuroendocrinology 32:36-43. 2007
    ..Reports of cognitive dysfunction may reflect affective and somatic manifestations of thyrotoxicosis and in most patients these symptoms disappear after treatment of Graves' thyrotoxicosis...
  29. ncbi If you don't ask (about memory), they probably won't tell
    Frans Boch Waldorff
    Research Unit and Department of General Practice, Institute of Public Health, University of Copenhagen, Denmark
    J Fam Pract 57:41-4. 2008
    ..To investigate the prevalence and potential clinical implications of self-reported memory impairment among elderly patients in general practice...
  30. ncbi Implementation of a clinical dementia guideline. A controlled study on the effect of a multifaceted strategy
    Frans Boch Waldorff
    Central Research Unit, Department of General Practice, Institute of Public Health, University of Copenhagen, Denmark
    Scand J Prim Health Care 21:142-7. 2003
    ..To assess the impact of a multifaceted implementation strategy aiming to improve GP adherence to a clinical guideline on dementia...
  31. ncbi Comparison of the Alzheimer's Disease Assessment Scale Cognitive Subscale and the Vascular Dementia Assessment Scale in differentiating elderly individuals with different degrees of white matter changes. The LADIS Study
    Raija Ylikoski
    Memory Research Unit, Department of Neurology, University of Helsinki, Helsinki, Finland
    Dement Geriatr Cogn Disord 24:73-81. 2007
    ..The objective of this study was to compare the results of the two scales among subjects with various degrees of white matter hyperintensities (WMHs)...
  32. ncbi Neurological letter from... Denmark
    Gunhild Waldemar
    Department of Neurology, Rigshospitalet, Section 2082, Copenhagen University Hospital, 9 Blegdamsvej, 2100 Copenhagen, Denmark
    Pract Neurol 7:272-4. 2007
  33. ncbi Validity of dementia diagnoses in the Danish hospital registers
    Thien Kieu Thi Phung
    Memory Disorders Research Group, Department of Neurology, The Centre of Neuroscience, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
    Dement Geriatr Cogn Disord 24:220-8. 2007
    ..The validity of dementia diagnoses in the Danish nationwide hospital registers was evaluated to determine the value of these registers in epidemiological research about dementia...
  34. ncbi [Lifestyle-related risk factors for dementia]
    Thien Kieu Thi Phung
    H S Righospitalet, Hukommelsesklinikken, Neurocentret, Neurologisk Klinik
    Ugeskr Laeger 168:3401-5. 2006
    ..Moreover, modification of cardiovascular risk factors during this period can potentially reduce risk for dementia...
  35. ncbi Semantic memory impairment in the earliest phases of Alzheimer's disease
    Asmus Vogel
    Memory Disorders Research Unit, Neuroscience Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Dement Geriatr Cogn Disord 19:75-81. 2005
    ..The results imply that assessment of semantic memory is relevant in the evaluation of patients with suspected AD...
  36. ncbi Impact of age-related cerebral white matter changes on the transition to disability -- the LADIS study: rationale, design and methodology
    Leonardo Pantoni
    Department of Neurological and Psychiatric Sciences, University of Florence, Florence, Italy
    Neuroepidemiology 24:51-62. 2005
    ..The study results may also help to standardize, on an international basis, tools and criteria to identify early stages of disability...
  37. ncbi Small vessel disease and general cognitive function in nondisabled elderly: the LADIS study
    Wiesje M van der Flier
    Alzheimer Center, Department of Neurology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
    Stroke 36:2116-20. 2005
    ..We investigated the independent contribution of WMH and lacunes to general cognitive function in a group of independently living elderly with varying degrees of small vessel disease...
  38. ncbi Identification and diagnostic evaluation of possible dementia in general practice. A prospective study
    Frans Boch Waldorff
    Research Unit and Department of General Practice, Institute of Public Health, University of Copenhagen, Øster Farimagsgade 5, PO Box 2099, DK 1014 Copenhagen K, Denmark
    Scand J Prim Health Care 23:221-6. 2005
    ..To investigate the rate of diagnostic evaluation of dementia for patients in whom a suspicion of dementia was raised, and to investigate reasons why a diagnostic evaluation was not always being performed...
  39. ncbi Prepulse inhibition in patients with Alzheimer's disease
    Anne Mette Hejl
    Memory Disorders Research Unit, The Neuroscience Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen 2100, Denmark
    Neurobiol Aging 25:1045-50. 2004
    ..Since mild AD is primarily associated with loss of cholinergic markers in the limbic regions this study suggests that acetylcholine only plays a minor role in the regulation of PPI...
  40. ncbi Patient- and proxy-reported utility in Alzheimer disease using the EuroQoL
    Linus Jönsson
    Neurotec, Section for Geriatric Epidemiology, Karolinska Institutet, Stockholm, Sweden
    Alzheimer Dis Assoc Disord 20:49-55. 2006
    ..The study shows that the EuroQoL can be used to rate utilities in Alzheimer disease, but there are important differences between patient- and proxy-ratings...
  41. ncbi Awareness of deficits in mild cognitive impairment and Alzheimer's disease: do MCI patients have impaired insight?
    Asmus Vogel
    Memory Disorders Research Unit, Neuroscience Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Dement Geriatr Cogn Disord 17:181-7. 2004
    ....
  42. ncbi Psychiatric morbidity in a neurology-based memory clinic: the effect of systematic psychiatric evaluation
    Anne Mette Hejl
    Memory Disorders Research Unit, Department of Neurology Department of Psychiatry, The Neuroscience Center, Copenhagen University Hospital, Rigshospitalet, Denmark
    J Am Geriatr Soc 51:1773-8. 2003
    ..To estimate the prevalence of psychiatric morbidity and the effect of systematic psychiatric evaluation in patients referred to a memory clinic in a neurological setting...
  43. ncbi Determinants of costs of care for patients with Alzheimer's disease
    Linus Jönsson
    Division of Geriatric Epidemiology, The Neurotec Department, Karolinska Institutet, Stockholm, Sweden
    Int J Geriatr Psychiatry 21:449-59. 2006
    ..Alzheimer's disease (AD), the most common cause of dementia, is a major cause of disability and care burden in the elderly. This study aims to estimate the costs of formal and informal care and identity determinants of care costs...
  44. ncbi Heterogeneity in executive impairment in patients with very mild Alzheimer's disease
    Jette Stokholm
    Memory Disorders Research Unit, Neuroscience Center, Copenhagen University Hospital, Rigshospitalet, Denmark
    Dement Geriatr Cogn Disord 22:54-9. 2006
    ..The aim of this study was to describe the frequency of impairment on a set of internationally well-known executive tests in patients with very mild AD...
  45. ncbi Diagnostic profile of young and middle-aged memory clinic patients
    Tina Vraamark Elberling
    Memory Disorders Research Unit, The Neuroscience Center, Rigshospitalet, Copenhagen University Hospital, Denmark
    Neurology 59:1259-62. 2002
    ..Cognitive symptoms in younger patients rarely reflect dementia but more often other medical and psychiatric conditions...
  46. ncbi Years of severe and isolated amnesia can precede the development of dementia in early-onset Alzheimer's disease
    Jette Stokholm
    Memory Disorders Research Unit, Neuroscience Centre, Copenhagen University Hospital, Rigshospitalet, Denmark
    Neurocase 11:48-55. 2005
    ..We argue that this is a case of prodromal AD, which illustrates an extreme version of the normal course with respect to slow progression of the disease and severity of amnesia early in the course...
  47. ncbi Patient versus informant reported quality of life in the earliest phases of Alzheimer's disease
    Asmus Vogel
    Memory Disorders Research Group, Neuroscience Center, Copenhagen University Hospital, Rigshospitalet, Denmark
    Int J Geriatr Psychiatry 21:1132-8. 2006
    ....
  48. ncbi Development of a neuropsychological battery for the Leukoaraiosis and Disability in the Elderly Study (LADIS): experience and baseline data
    Sofia Madureira
    Servico de Neurologia, Centro de Estudos Egas Moniz, Hospital de Santa Maria, Lisboa, Portugal
    Neuroepidemiology 27:101-16. 2006
    ..In the LADIS population baseline data, older age and lower educational levels negatively influence neuropsychological performance...
  49. pmc Differential impact of cerebral white matter changes, diabetes, hypertension and stroke on cognitive performance among non-disabled elderly. The LADIS study
    Ana Verdelho
    Neurology Department, Centro de Estudos Egas Moniz, Santa Maria Hospital, Lisbon, Portugal
    J Neurol Neurosurg Psychiatry 78:1325-30. 2007
    ..Our aim was to study the influence of vascular risk factors and ARWMC on the neuropsychological performance of an independent elderly population, to see if vascular risk factors impair cognition in addition to the effects of ARWMC...
  50. ncbi The executive interview as a screening test for executive dysfunction in patients with mild dementia
    Jette Stokholm
    Memory Disorders Research Unit, Neuroscience Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    J Am Geriatr Soc 53:1577-81. 2005
    ..To validate the Executive Interview (EXIT25) as a screening instrument for executive cognitive dysfunction in patients with mild dementia...
  51. pmc The pilot European Alzheimer's Disease Neuroimaging Initiative of the European Alzheimer's Disease Consortium
    Giovanni B Frisoni
    IRCCS Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy
    Alzheimers Dement 4:255-64. 2008
    ..A pilot study has been carried out in Europe to test the feasibility of the adoption of the ADNI platform (pilot E-ADNI)...
  52. ncbi [100 years with Alzheimer disease]
    Gunhild Waldemar
    Ugeskr Laeger 168:3399. 2006
  53. ncbi Temporal lobe hypoperfusion in isolated amnesia with slow onset: a single photon emission computer tomography study
    Peter Høgh
    Memory Disorders Research Unit, The Neuroscience Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Dement Geriatr Cogn Disord 18:15-23. 2004
    ..These findings may indicate the presence of a progressive degenerative illness affecting multiple brain regions at its early or preclinical stage...
  54. ncbi Neurofilament inclusion body disease: a new proteinopathy?
    Keith A Josephs
    Department of Neurology, Mayo Clinic, Rochester, MN, USA
    Brain 126:2291-303. 2003
    ..We propose the term neurofilament inclusion body disease for this entity...
  55. ncbi [Frontotemporal dementia--new understanding of Pick disease]
    Jette Stokholm
    Hukommelsesklinikken, H S Rigshospitalet, DK 2100 Købehavn ø
    Ugeskr Laeger 165:553-6. 2003
    ..The article gives a short overview of new knowledge in this field. Clinical criteria are in focus, but neuropathological aspects are also mentioned...
  56. ncbi An economic evaluation of donepezil in mild to moderate Alzheimer's disease: results of a 1-year, double-blind, randomized trial
    Anders Wimo
    Department of Family Medicine, Umea University, Umea, Sweden
    Dement Geriatr Cogn Disord 15:44-54. 2003
    ....
  57. doi Usability of cerebrospinal fluid biomarkers in a tertiary memory clinic
    Camilla Brandt
    Memory Clinic, Section 6702, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    Dement Geriatr Cogn Disord 25:553-8. 2008
    ..The aim of the study was to assess the usability of these biomarkers in a mixed population of tertiary dementia referral patients in a university-based memory clinic...
  58. doi Consensus statement on genetic research in dementia
    Marcel G M Olde Rikkert
    Department of Geriatrics, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
    Am J Alzheimers Dis Other Demen 23:262-6. 2008
    ..The consensus statement aims to stimulate ethically acceptable research in the field of dementia and the protection of vulnerable elderly patients with dementia from application of inadequate research methods or designs...
  59. doi Progression of white matter hyperintensities and incidence of new lacunes over a 3-year period: the Leukoaraiosis and Disability study
    Alida A Gouw
    Department of Neurology, Alzheimer Center and Image Analysis Center, Vrije Universiteit Medical Center, PO Box 7057, 1007 MB Amsterdam, The Netherlands
    Stroke 39:1414-20. 2008
    ..We studied the natural course of white matter hyperintensities (WMH) and lacunes, the main MRI representatives of small vessel disease, over time and evaluated possible predictors for their development...
  60. ncbi [Dementia--genetic aspects]
    Suzanne Granhøj Lindquist
    H S Rigshospitalet, Neurocentret, Neurologisk Klinik, H S Hukommelsesklinikken
    Ugeskr Laeger 168:3405-8. 2006
    ..Although inherited dementia disorders are generally rare, a genetic basis should always be considered when facing a patient with a recently clinically diagnosed dementia disorder...
  61. pmc Corpus callosum atrophy is associated with mental slowing and executive deficits in subjects with age-related white matter hyperintensities: the LADIS Study
    Hanna Jokinen
    Department of Psychology, University of Helsinki, Helsinki, Finland
    J Neurol Neurosurg Psychiatry 78:491-6. 2007
    ..Previous research has indicated that corpus callosum atrophy is associated with global cognitive decline in neurodegenerative diseases, but few studies have investigated specific cognitive functions...
  62. ncbi Evidence-based evaluation of magnetic resonance imaging as a diagnostic tool in dementia workup
    Lars Olof Wahlund
    Department of Neurobiology, Caring Sciences and Society, Division of Clinical Geriatrics, Karolinska Institutet, Stockholm, Sweden
    Top Magn Reson Imaging 16:427-37. 2005
    ..A great interest has been put in whether atrophy in the medial temporal lobe can serve as an early diagnostic marker for Alzheimer disease...
  63. ncbi Risk of rapid global functional decline in elderly patients with severe cerebral age-related white matter changes: the LADIS study
    Domenico Inzitari
    Department of Neurological and Psychiatric Sciences, University of Florence, Florence, Italy
    Arch Intern Med 167:81-8. 2007
    ..The LADIS (LeukoAraiosis and DISability) Study primarily aims to assess ARWMCs as a determinant of global functional decline in the elderly population...
  64. ncbi Novel panel of cerebrospinal fluid biomarkers for the prediction of progression to Alzheimer dementia in patients with mild cognitive impairment
    Anja H Simonsen
    Biomarker Discovery Center Facility, Ciphergen Biosystems, Inc, 2100 Copenhagen O, Denmark
    Arch Neurol 64:366-70. 2007
    ..To use proteomic analysis of cerebrospinal fluid to discover novel proteins and peptides able to differentiate between patients with stable mild cognitive impairment (MCI) and those who will progress to Alzheimer disease (AD)...
  65. ncbi [Biochemical markers for Alzheimer disease]
    Justyna Maria Czarna
    Statens Serum Institut, Autoimmunafdelingen, og H S Rigshospitalet, Hukommelsesklinikken, Neurologisk afdeling
    Ugeskr Laeger 168:1010-4. 2006
    ....
  66. ncbi Leukoaraiosis predicts hidden global functioning impairment in nondisabled older people: the LADIS (Leukoaraiosis and Disability in the Elderly) Study
    Leonardo Pantoni
    Department of Neurological and Psychiatric Sciences, University of Florence, Florence, Italy
    J Am Geriatr Soc 54:1095-101. 2006
    ..To determine whether leukoaraiosis severity is independently associated with differences in global functioning in nondisabled elderly patients...
  67. ncbi Impact of white matter hyperintensities scoring method on correlations with clinical data: the LADIS study
    Elisabeth C W van Straaten
    Department of Neurology and Alzheimer Center, VU Medical Center, Amsterdam, The Netherlands
    Stroke 37:836-40. 2006
    ..Associations may depend on the method used for measuring WMH. We investigated the ability of different WMH scoring methods to detect differences in WMH load between groups with and without symptoms...
  68. ncbi Visual rating and ROI-based parametric analysis of rCBF SPECT in patients with mild or questionable dementia: a comparative study
    Peter Høgh
    Memory Disorders Research Group, Department of Neurology, Copenhagen University Hospital, Rigshospitalet, Neuroscience Centre, Copenhagen, Denmark
    Dement Geriatr Cogn Disord 24:429-33. 2007
    ....
  69. ncbi Caries prevalence in older persons with and without dementia
    Birita Ellefsen
    Copenhagen Gerontological Oral Health Research Centre, School of Dentistry, University of Copenhagen, Copenhagen, Denmark
    J Am Geriatr Soc 56:59-67. 2008
    ....
  70. ncbi Sparse decomposition and modeling of anatomical shape variation
    Karl Sjöstrand
    Department of Informatics and Mathematical Modelling, Technical University of Denmark, DK 2800 Kgs Lyngby, Denmark
    IEEE Trans Med Imaging 26:1625-35. 2007
    ....
  71. doi Atypical early-onset Alzheimer's disease caused by the Iranian APP mutation
    Suzanne Granhøj Lindquist
    Memory Disorders Research Group, Department of Neurology, Copenhagen University Hospital Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    J Neurol Sci 268:124-30. 2008
    ..We describe atypical phenotypic features in a family with a pathogenic APP gene mutation and discuss possible explanations for these atypical features...
  72. ncbi [Strategies for the diagnosis of dementia. Experiences of collaboration between general practitioners and district nurses]
    Frans Boch Waldorff
    Central Forskningsenhed for Almen Praksis, Panum Instituttet, Københavns Universitet, DK 2200 København N
    Ugeskr Laeger 164:3767-70. 2002
    ..The aim was to explore the context and experiences of collaboration between the general practitioner (GP) and the district nurse (DN) on diagnosing dementia, in order to identify possible procedures to improve care...