Ole William Petersen

Summary

Affiliation: University of Copenhagen
Country: Denmark

Publications

  1. ncbi Normal and tumor-derived myoepithelial cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition
    Thorarinn Gudjonsson
    Structural Cell Biology Unit, Institute of Medical Anatomy, The Panum Institute, DK-2200 Copenhagen N, Denmark
    J Cell Sci 115:39-50. 2002
  2. ncbi Myoepithelial cells: good fences make good neighbors
    Melissa C Adriance
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA
    Breast Cancer Res 7:190-7. 2005
  3. ncbi [Pathogenesis of breast cancer]
    Ole William Petersen
    Københavns Universitet, Institut for Cellulaer og Molekylaer Medicin, Panumbygningen, Det Sundhedsvidenskabelige Fakultet, København N
    Ugeskr Laeger 169:2968-72. 2007
  4. ncbi The plasticity of human breast carcinoma cells is more than epithelial to mesenchymal conversion
    O W Petersen
    Structural Cell Biology Unit, Institute of Medical Anatomy, The Panum Institute, Copenhagen, Denmark
    Breast Cancer Res 3:213-7. 2001
  5. ncbi Epithelial progenitor cell lines as models of normal breast morphogenesis and neoplasia
    Ole William Petersen
    Structural Cell Biology Unit, Institute of Medical Anatomy, The Panum Institute, Copenhagen, Denmark
    Cell Prolif 36:33-44. 2003
  6. ncbi Epithelial to mesenchymal transition in human breast cancer can provide a nonmalignant stroma
    Ole William Petersen
    Structural Cell Biology Unit, Department of Medical Anatomy, Section A, The Panum Institute, Copenhagen, Denmark
    Am J Pathol 162:391-402. 2003
  7. ncbi To create the correct microenvironment: three-dimensional heterotypic collagen assays for human breast epithelial morphogenesis and neoplasia
    Thorarinn Gudjonsson
    Structural Cell Biology Unit, Institute of Medical Anatomy, The Panum Institute, DK-2200, Copenhagen N, Denmark
    Methods 30:247-55. 2003
  8. ncbi Collagen gel contraction serves to rapidly distinguish epithelial- and mesenchymal-derived cells irrespective of alpha-smooth muscle actin expression
    Helga Lind Nielsen
    Structural Cell Biology Unit, Institute of Medical Anatomy, The Panum Institute, Copenhagen, Denmark
    In Vitro Cell Dev Biol Anim 39:297-303. 2003
  9. ncbi Isolation, immortalization, and characterization of a human breast epithelial cell line with stem cell properties
    Thorarinn Gudjonsson
    Structural Cell Biology Unit, Institute of Medical Anatomy, The Panum Institute, DK-2200 Copenhagen N, Denmark
    Genes Dev 16:693-706. 2002
  10. ncbi Maintenance of cell type diversification in the human breast
    Agla Jael Rubner Fridriksdottir
    Structural Cell Biology Unit, Institute of Medical Anatomy, The Panum Institute, Copenhagen, Denmark
    J Mammary Gland Biol Neoplasia 10:61-74. 2005

Collaborators

Detail Information

Publications12

  1. ncbi Normal and tumor-derived myoepithelial cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition
    Thorarinn Gudjonsson
    Structural Cell Biology Unit, Institute of Medical Anatomy, The Panum Institute, DK-2200 Copenhagen N, Denmark
    J Cell Sci 115:39-50. 2002
    ..These results have important implications for the role of myoepithelial cells in maintenance of polarity in normal breast and how they may function as structural tumor suppressors...
  2. ncbi Myoepithelial cells: good fences make good neighbors
    Melissa C Adriance
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA
    Breast Cancer Res 7:190-7. 2005
    ....
  3. ncbi [Pathogenesis of breast cancer]
    Ole William Petersen
    Københavns Universitet, Institut for Cellulaer og Molekylaer Medicin, Panumbygningen, Det Sundhedsvidenskabelige Fakultet, København N
    Ugeskr Laeger 169:2968-72. 2007
    ..Here we discuss the possible existence of normal and cancer stem cells in the human breast and in breast cancer and their potential role in the evolution of this disease...
  4. ncbi The plasticity of human breast carcinoma cells is more than epithelial to mesenchymal conversion
    O W Petersen
    Structural Cell Biology Unit, Institute of Medical Anatomy, The Panum Institute, Copenhagen, Denmark
    Breast Cancer Res 3:213-7. 2001
    ....
  5. ncbi Epithelial progenitor cell lines as models of normal breast morphogenesis and neoplasia
    Ole William Petersen
    Structural Cell Biology Unit, Institute of Medical Anatomy, The Panum Institute, Copenhagen, Denmark
    Cell Prolif 36:33-44. 2003
    ..As more than 90% of breast cancers arise in TDLUs and more than 90% are also cytokeratin 19-positive, we suggest that this cell population contains a breast-cancer progenitor...
  6. ncbi Epithelial to mesenchymal transition in human breast cancer can provide a nonmalignant stroma
    Ole William Petersen
    Structural Cell Biology Unit, Department of Medical Anatomy, Section A, The Panum Institute, Copenhagen, Denmark
    Am J Pathol 162:391-402. 2003
    ..We conclude that breast cancer can generate its own nonmalignant stroma and that one function for this is that of a reciprocal interaction with epithelial tumor cells to facilitate tumor growth...
  7. ncbi To create the correct microenvironment: three-dimensional heterotypic collagen assays for human breast epithelial morphogenesis and neoplasia
    Thorarinn Gudjonsson
    Structural Cell Biology Unit, Institute of Medical Anatomy, The Panum Institute, DK-2200, Copenhagen N, Denmark
    Methods 30:247-55. 2003
    ..Few if any of these observations would have been possible on two-dimensional tissue culture plastic...
  8. ncbi Collagen gel contraction serves to rapidly distinguish epithelial- and mesenchymal-derived cells irrespective of alpha-smooth muscle actin expression
    Helga Lind Nielsen
    Structural Cell Biology Unit, Institute of Medical Anatomy, The Panum Institute, Copenhagen, Denmark
    In Vitro Cell Dev Biol Anim 39:297-303. 2003
    ..It is concluded that epithelial-derived mesenchymal-like cells are functionally defective within a connective tissue environment irrespective of an apparent contractile phenotype...
  9. ncbi Isolation, immortalization, and characterization of a human breast epithelial cell line with stem cell properties
    Thorarinn Gudjonsson
    Structural Cell Biology Unit, Institute of Medical Anatomy, The Panum Institute, DK-2200 Copenhagen N, Denmark
    Genes Dev 16:693-706. 2002
    ..Thus, MUC(-)/ESA(+) epithelial cells within the luminal epithelial lineage may function as precursor cells of terminal duct lobular units in the human breast...
  10. ncbi Maintenance of cell type diversification in the human breast
    Agla Jael Rubner Fridriksdottir
    Structural Cell Biology Unit, Institute of Medical Anatomy, The Panum Institute, Copenhagen, Denmark
    J Mammary Gland Biol Neoplasia 10:61-74. 2005
    ..The present review discusses the current approaches to address these issues and the measures taken to unravel and maintain cell type diversification for further investigation...
  11. ncbi A function for filamentous alpha-smooth muscle actin: retardation of motility in fibroblasts
    L Rønnov-Jessen
    Structural Cell Biology Unit, Institute of Medical Anatomy, The Panum Institute, Copenhagen, Denmark
    J Cell Biol 134:67-80. 1996
    ..We propose that an important function of filamentous alpha-sm actin is to immobilize the cells...
  12. ncbi Human breast microvascular endothelial cells retain phenotypic traits in long-term finite life span culture
    Valgardur Sigurdsson
    Faculty of Medicine, University of Iceland, Reykjavik, Iceland
    In Vitro Cell Dev Biol Anim 42:332-40. 2006
    ..These cells will form the basis for studies on the role of endothelial cells in breast morphogenesis...