Allan S Wiik

Summary

Affiliation: University of Copenhagen
Country: Denmark

Publications

  1. doi request reprint Clinical and pathophysiological significance of anti-neutrophil cytoplasmic autoantibodies in vasculitis syndromes
    Allan Wiik
    Department of Clinical Biochemistry and Immunology, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark
    Mod Rheumatol 19:590-9. 2009
  2. doi request reprint Autoantibodies in ANCA-associated vasculitis
    Allan S Wiik
    Department of Autoimmunology, Statens Serum Institut, DK 2300 Copenhagen S, Denmark
    Rheum Dis Clin North Am 36:479-89. 2010
  3. doi request reprint All you wanted to know about anti-CCP but were afraid to ask
    Allan S Wiik
    Department of Clinical Biochemistry and Immunology, Statens Serum Institut, Copenhagen, Denmark
    Autoimmun Rev 10:90-3. 2010
  4. pmc The use of citrullinated peptides and proteins for the diagnosis of rheumatoid arthritis
    Ger Jm Pruijn
    Department of Biomolecular Chemistry 271, Nijmegen Center for Molecular Life Sciences, Institute for Molecules and Materials, Radboud University Nijmegen, PO Box 9101, NL 6500 HB Nijmegen, The Netherlands
    Arthritis Res Ther 12:203. 2010
  5. doi request reprint Antinuclear antibodies: a contemporary nomenclature using HEp-2 cells
    Allan S Wiik
    Department of Clinical Biochemistry and Immunology, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark
    J Autoimmun 35:276-90. 2010
  6. doi request reprint Drug-induced vasculitis
    Allan Wiik
    Department of Autoimmunology, Statens Serum Institut, Copenhagen, Denmark
    Curr Opin Rheumatol 20:35-9. 2008
  7. pmc Clinical and laboratory characteristics of drug-induced vasculitic syndromes
    Allan Wiik
    Department of Autoimmunology, Statens Serum Institut, Copenhagen, Denmark
    Arthritis Res Ther 7:191-2. 2005
  8. ncbi request reprint Tissue transglutaminase and endomysial autoantibodies measured in an historical cohort of children and young adults in whom coeliac disease was suspected
    Birgitte Weile
    Department of Autoimmunology, Statens Serum Institut, Copenhagen, Denmark
    Eur J Gastroenterol Hepatol 14:71-6. 2002
  9. ncbi request reprint [Forty four pregnancies with idiopathic thrombocytopenic purpura]
    Tine Boe Mortensen
    H S Rigshospitalet, Obstetrisk Klinik, Juliane Marie Centret
    Ugeskr Laeger 164:3968-72. 2002
  10. ncbi request reprint Anti-neutrophil cytoplasmic autoantibody (ANCA) profiles in propylthiouracil-induced lupus-like manifestations in monozygotic triplets with hyperthyroidism
    Troels Herlin
    Department of Pediatrics, Skejby Sygehus, Aarhus University Hospital, Denmark
    Scand J Rheumatol 31:46-9. 2002

Collaborators

Detail Information

Publications30

  1. doi request reprint Clinical and pathophysiological significance of anti-neutrophil cytoplasmic autoantibodies in vasculitis syndromes
    Allan Wiik
    Department of Clinical Biochemistry and Immunology, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark
    Mod Rheumatol 19:590-9. 2009
    ..The review concludes that the presence of ANCA is likely to become an important criterion for diagnosing idiopathic small vessel vasculitis...
  2. doi request reprint Autoantibodies in ANCA-associated vasculitis
    Allan S Wiik
    Department of Autoimmunology, Statens Serum Institut, DK 2300 Copenhagen S, Denmark
    Rheum Dis Clin North Am 36:479-89. 2010
    ..These autoantibodies are assumed to play a role in the initiation and propagation of chronic inflammation. ANCAs are valuable for clinical diagnosis, follow-up, and guidance in therapy...
  3. doi request reprint All you wanted to know about anti-CCP but were afraid to ask
    Allan S Wiik
    Department of Clinical Biochemistry and Immunology, Statens Serum Institut, Copenhagen, Denmark
    Autoimmun Rev 10:90-3. 2010
    ..Still, larger and strictly stratified studies are highly warranted to substantiate this conclusion...
  4. pmc The use of citrullinated peptides and proteins for the diagnosis of rheumatoid arthritis
    Ger Jm Pruijn
    Department of Biomolecular Chemistry 271, Nijmegen Center for Molecular Life Sciences, Institute for Molecules and Materials, Radboud University Nijmegen, PO Box 9101, NL 6500 HB Nijmegen, The Netherlands
    Arthritis Res Ther 12:203. 2010
    ..Finally, the levels of anti-CCP2 and anti-CCP3 (and possibly anti-mutated citrullinated vimentin) in rheumatoid arthritis patients are not significantly influenced by TNFalpha blocking agents...
  5. doi request reprint Antinuclear antibodies: a contemporary nomenclature using HEp-2 cells
    Allan S Wiik
    Department of Clinical Biochemistry and Immunology, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark
    J Autoimmun 35:276-90. 2010
    ..All results from this project were reported to the European Commission but have not previously been published in scientific literature. This communication presents the final results of agreed image classifications...
  6. doi request reprint Drug-induced vasculitis
    Allan Wiik
    Department of Autoimmunology, Statens Serum Institut, Copenhagen, Denmark
    Curr Opin Rheumatol 20:35-9. 2008
    ..The clinical phenotypes vary from single tissue or organ involvement to severe systemic inflammatory disease dominated by vasculitis and sometimes organ failure...
  7. pmc Clinical and laboratory characteristics of drug-induced vasculitic syndromes
    Allan Wiik
    Department of Autoimmunology, Statens Serum Institut, Copenhagen, Denmark
    Arthritis Res Ther 7:191-2. 2005
    ..Clinically, skin vasculitis and arthralgias predominated and renal vasculitis was rare...
  8. ncbi request reprint Tissue transglutaminase and endomysial autoantibodies measured in an historical cohort of children and young adults in whom coeliac disease was suspected
    Birgitte Weile
    Department of Autoimmunology, Statens Serum Institut, Copenhagen, Denmark
    Eur J Gastroenterol Hepatol 14:71-6. 2002
    ..To evaluate whether anti-endomysial and anti-transglutaminase antibodies are relevant important markers of coeliac disease in an historical group of patient sera...
  9. ncbi request reprint [Forty four pregnancies with idiopathic thrombocytopenic purpura]
    Tine Boe Mortensen
    H S Rigshospitalet, Obstetrisk Klinik, Juliane Marie Centret
    Ugeskr Laeger 164:3968-72. 2002
    ..The aim of this project was to describe the course of pregnancy with idiopathic thrombocytopenic purpura (ITP) and to estimate risk factors and indications for treatment...
  10. ncbi request reprint Anti-neutrophil cytoplasmic autoantibody (ANCA) profiles in propylthiouracil-induced lupus-like manifestations in monozygotic triplets with hyperthyroidism
    Troels Herlin
    Department of Pediatrics, Skejby Sygehus, Aarhus University Hospital, Denmark
    Scand J Rheumatol 31:46-9. 2002
    ..Triplet A and B, but not C, both developed a strongly positive elastase-ANCA. Our results confirm the importance of a genetic factor influencing the susceptibility to drug-induced LE...
  11. pmc Autoantibodies in vasculitis
    Allan Wiik
    Department of Autoimmunology, Statens Serum Institut, Copenhagen, Denmark
    Arthritis Res Ther 5:147-52. 2003
    ..Although autoantibodies to endothelial cells may be important players in the pathogenesis of several vasculitic conditions, they have not gained clinical popularity because of lack of standardized detection methods...
  12. ncbi request reprint [Laboratory diagnostics in rheumatology]
    Allan Wiik
    Autoimmunafdelingen, Statens Serum Institut, bygning 81, rum 544, Artillerivej 5, DK 2300 København S
    Ugeskr Laeger 164:610-4. 2002
    ..A clinically important use of serodiagnostics can only be implemented by a close collaboration between clinicians and laboratory specialists. A tentative diagnosis is the best basis for ordering and interpreting laboratory results...
  13. ncbi request reprint The immune response to citrullinated proteins in patients with rheumatoid arthritis: genetic, clinical, technical, and epidemiological aspects
    Allan S Wiik
    Department of Autoimmunology, Statens Serum Institut, Copenhagen S, Denmark
    Clin Rev Allergy Immunol 32:13-22. 2007
    ..The antibody can sometimes be found several years before the onset of clinical symptoms of RA, which may represent an open window for preventive measures to be taken...
  14. ncbi request reprint Cutting edge diagnostics in rheumatology: the role of patients, clinicians, and laboratory scientists in optimizing the use of autoimmune serology
    Allan S Wiik
    Statens Serum Institut, Copenhagen, Denmark
    Arthritis Rheum 51:291-8. 2004
  15. ncbi request reprint Untreated silicone breast implant rupture
    Lisbet R Hölmich
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Plast Reconstr Surg 114:204-14; discussion 215-6. 2004
    ..Because implant ruptures often occur asymptomatically, any woman with silicone implants, regardless of rupture status, should be evaluated at regular intervals...
  16. ncbi request reprint Neutrophil-specific autoantibodies in chronic inflammatory bowel diseases
    Allan Wiik
    Department of Autoimmunology, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark
    Autoimmun Rev 1:67-72. 2002
    ..Laboratory reports on NSA-positivity must be clearly distinguishable from reports on ANCA to help avoid clinical misinterpretation...
  17. ncbi request reprint IgG and IgM isotypes of anti-cardiolipin and anti-beta2-glycoprotein i antibodies reflect different forms of recent thrombo-embolic events
    Henning Locht
    Department of Autoimmunology, Statens Serum Institut, 2300, Copenhagen S, Denmark
    Clin Rheumatol 25:246-50. 2006
    ....
  18. ncbi request reprint Appropriateness of autoantibody testing in clinical medicine
    Allan S Wiik
    Department of Autoimmunology, Statens Serum Institut, Bldg 81, 5th Floor, Room 544, Artillerivej 5, DK 2300 Copenhagen S, Denmark
    Clin Chim Acta 333:177-80. 2003
    ..Pathologically expressed autoantibodies reflect ongoing immune-mediated inflammation in patients and may even be regarded as surrogate markers of disease prognosis and clinical outcome in certain clinical settings...
  19. ncbi request reprint P53 autoantibodies in sera from Danish ovarian cancer patients and their correlation with clinical data and prognosis
    Estrid V S Høgdall
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    APMIS 110:545-53. 2002
    ..The presence of increased serum p53 AAb in patients with diagnosed OC could not be correlated with any clinical data and preoperative serum p53 AAb status had no evident value...
  20. ncbi request reprint Prevalence of antibodies against oxidised LDL in a cohort of 163 patients with positive anti-phospholipid antibodies and recent thrombosis
    Henning Locht
    Department of Autoimmunology, Building 81, 5th Floor, Statens Serum Institut, Artillerivej 5, 2300, Copenhagen S, Denmark
    Rheumatol Int 26:416-21. 2006
    ..However, a-oxLDL antibodies appear to define a subset of patients, who were older, had more arterial vascular disease, and with no apparent association to the presence of IgG aCL...
  21. ncbi request reprint The influence of pregnancy on the development of autoimmunity in chronic lymphocytic leukemia
    Viggo Jønsson
    Department of Hematology, Rigshospital, School of Medicine, University of Copenhagen, Copenhagen, Denmark
    Leuk Lymphoma 47:1481-7. 2006
    ..The spectrum of autoimmunity suggests that pregnancy-related alloimmunization may be involved in the development of autoimmunity in CLL...
  22. ncbi request reprint Induction of biologically active antineutrophil cytoplasmic antibodies by immunization with human apoptotic polymorphonuclear leukocytes
    Lubica Rauova
    Center for Autoimmune Diseases, Department of Medicine B, Sheba Medical Center, Tel Hashomer, Israel
    Clin Immunol 103:69-78. 2002
    ..These results support the hypothesis that neutrophil-specific antigens presented on the cell membranes of apoptotic PMN may induce ANCA in the proper conditions...
  23. ncbi request reprint A critical evaluation of enzyme immunoassay kits for detection of antinuclear autoantibodies of defined specificities. II. Potential for quantitation of antibody content
    Eng M Tan
    Autoantibody Standardization Committee in Rheumatic and Related Disorders of the International Union of Immunological Societies, The World Health Organization, The Arthritis Foundation, and Centers for Disease Control and Prevention
    J Rheumatol 29:68-74. 2002
    ..To analyze the performance of different commercial enzyme immunoassay (EIA) kits for measuring antibody levels of antinuclear antibodies (ANA) specific for double stranded (ds) DNA, SSB/La, Sm, and Scl-70...
  24. ncbi request reprint AutoAbSC.Org -- Autoantibody Standardization Committee in 2006
    Edward K L Chan
    Department of Oral Biology, University of Florida, Health Science Center, 1600 SW Archer Road, Gainesville, FL 32610 0424, USA
    Autoimmun Rev 6:577-80. 2007
    ..A web site has been developed under "AutoAbSC.Org" to communicate to the wider stakeholder community and to facilitate ongoing activities in continuing the mission in autoantibody standardization...
  25. ncbi request reprint Autoantibody response to BPI predict disease severity and outcome in cystic fibrosis
    Malin Carlsson
    Department of Laboratory Medicine, Section of Microbiology, Immunology and Glycobiology, Lund University, S 221 85 Lund, Sweden
    J Cyst Fibros 6:228-33. 2007
    ..In the present study, we investigated BPI-ANCA as a prognostic marker and its relation to P. aeruginosa colonization and lung function...
  26. pmc International multicenter evaluation of autoantibodies to ribosomal P proteins
    Michael Mahler
    Dr Fooke Laboratorien GmbH, Mainstr 85, 41469 Neuss, Germany
    Clin Vaccine Immunol 13:77-83. 2006
    ..We confirm previously reported associations of antiribosomal antibodies with clinical symptoms and serological findings. Remarkably, we found a lower occurrence of serositis in Rib-P-positive lupus patients...
  27. ncbi request reprint [Congenital heart block and autoantibodies]
    Niels H H Heegaard
    Statens Serum Institut, Autoimmunafdelingen
    Ugeskr Laeger 167:3775-6. 2005
    ..It may prove beneficial to screen all expectant mothers for anti-Ro52 autoantibodies. Decisions about this will require further studies of the diagnostic performance of the Ro52 autoantibody test...
  28. ncbi request reprint Long-term health status of Danish women with silicone breast implants
    Vibeke B Breiting
    Holte Clinic of Plastic Surgery, Denmark
    Plast Reconstr Surg 114:217-26; discussion 227-8. 2004
    ..The authors' finding of excess use of drugs for treatment of depression and anxiety among women with breast implants may warrant further investigation...
  29. ncbi request reprint Addendum to the International Consensus Statement on testing and reporting of antineutrophil cytoplasmic antibodies. Quality control guidelines, comments, and recommendations for testing in other autoimmune diseases
    Judy Savige
    University of Melbourne, Department of Medicine, Austin and Repatriation Medical Centre, Heidelberg, VIC 3084, Australia
    Am J Clin Pathol 120:312-8. 2003
    ....
  30. pmc The use and abuse of commercial kits used to detect autoantibodies
    Marvin J Fritzler
    Faculty of Medicine, University of Calgary, Alberta, Canada
    Arthritis Res Ther 5:192-201. 2003
    ..It is suggested that a higher level of commitment and partnership between all of the participants is required to achieve the goal of improving the quality of patient care through the use of autoantibody testing and analysis...