Michael Timm

Summary

Affiliation: University of Copenhagen
Country: Denmark

Publications

  1. doi request reprint Immunomodulatory effects of honey cannot be distinguished from endotoxin
    Michael Timm
    Department of Pharmacology and Pharmacotherapy, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, DK 2100 Copenhagen, Denmark
    Cytokine 42:113-20. 2008
  2. doi request reprint Cryopreservation of differentiated HL-60 cells for pyrogen testing
    Michael Timm
    Department of Pharmacology and Pharmacotherapy, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, DK 2100 Copenhagen, Denmark
    J Immunol Methods 339:146-52. 2008
  3. pmc Assessment of the total inflammatory potential of bioaerosols by using a granulocyte assay
    Michael Timm
    Department of Pharmacology and Pharmacotherapy, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, DK 2100 Copenhagen, Denmark
    Appl Environ Microbiol 75:7655-62. 2009
  4. doi request reprint Immunomodulatory effects of testosterone evaluated in all-trans retinoic acid differentiated HL-60 cells, granulocytes, and monocytes
    Alex Boje
    Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark
    Int Immunopharmacol 12:573-9. 2012
  5. doi request reprint Effect of moist heat sterilisation on the pyrogenicity of cell wall components from Staphylococcus aureus
    Lise Moesby
    Department of Pharmacology and Pharmacotherapy, Faculty of Pharmaceutical Sciences, University of Copenhagen, 2 Universitetsparken, DK 2100 Copenhagen, Denmark
    Eur J Pharm Sci 35:442-6. 2008
  6. ncbi request reprint Utilization of the human cell line HL-60 for chemiluminescence based detection of microorganisms and related substances
    Michael Timm
    Department of Pharmacology, The Danish University of Pharmaceutical Sciences, Universitetsparken 2, 2100 Copenhagen, Denmark
    Eur J Pharm Sci 27:252-8. 2006
  7. doi request reprint The effect of dietary fish oil-supplementation to healthy young men on oxidative burst measured by whole blood chemiluminescence
    Stine Bartelt
    Department of Human Nutrition, Faculty of Life Sciences, University of Copenhagen, Rolighedsvej 30, DK 1958 Frederiksberg C, Denmark
    Br J Nutr 99:1230-8. 2008

Collaborators

Detail Information

Publications7

  1. doi request reprint Immunomodulatory effects of honey cannot be distinguished from endotoxin
    Michael Timm
    Department of Pharmacology and Pharmacotherapy, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, DK 2100 Copenhagen, Denmark
    Cytokine 42:113-20. 2008
    ..We speculate that the observed in vitro immunomodulatory effects of honey might solely be explained by the endotoxin content in the natural honeys...
  2. doi request reprint Cryopreservation of differentiated HL-60 cells for pyrogen testing
    Michael Timm
    Department of Pharmacology and Pharmacotherapy, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, DK 2100 Copenhagen, Denmark
    J Immunol Methods 339:146-52. 2008
    ..In conclusion, ATRA differentiated HL-60 cells are cryopreservable and retain reactivity upon thawing. It is therefore possible to produce an in-vitro in-house pyrogen test kit for medicines and related products...
  3. pmc Assessment of the total inflammatory potential of bioaerosols by using a granulocyte assay
    Michael Timm
    Department of Pharmacology and Pharmacotherapy, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, DK 2100 Copenhagen, Denmark
    Appl Environ Microbiol 75:7655-62. 2009
    ..Therefore, potential occupational health effects related to inflammation of the airways in a working environment can be estimated using this assay...
  4. doi request reprint Immunomodulatory effects of testosterone evaluated in all-trans retinoic acid differentiated HL-60 cells, granulocytes, and monocytes
    Alex Boje
    Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark
    Int Immunopharmacol 12:573-9. 2012
    ..Testosterone, at pharmacological doses, was also shown to suppress generation of reactive oxygen species and interleukin-8 in human granulocytes and monocytes, respectively, to a similar extent as observed in differentiated HL-60 cells...
  5. doi request reprint Effect of moist heat sterilisation on the pyrogenicity of cell wall components from Staphylococcus aureus
    Lise Moesby
    Department of Pharmacology and Pharmacotherapy, Faculty of Pharmaceutical Sciences, University of Copenhagen, 2 Universitetsparken, DK 2100 Copenhagen, Denmark
    Eur J Pharm Sci 35:442-6. 2008
    ..In conclusion the terminal moist heat sterilisation procedures described by the European Pharmacopoeia are not able to inactivate the interleukin-6 inducing activity of S. aureus lipoteichoic acid and peptidoglycan...
  6. ncbi request reprint Utilization of the human cell line HL-60 for chemiluminescence based detection of microorganisms and related substances
    Michael Timm
    Department of Pharmacology, The Danish University of Pharmaceutical Sciences, Universitetsparken 2, 2100 Copenhagen, Denmark
    Eur J Pharm Sci 27:252-8. 2006
    ..Furthermore, the utilization of the assay for pyrogenic examination of recombinant drugs derived from yeast expression systems would be relevant to examine...
  7. doi request reprint The effect of dietary fish oil-supplementation to healthy young men on oxidative burst measured by whole blood chemiluminescence
    Stine Bartelt
    Department of Human Nutrition, Faculty of Life Sciences, University of Copenhagen, Rolighedsvej 30, DK 1958 Frederiksberg C, Denmark
    Br J Nutr 99:1230-8. 2008
    ..44, P = 0.016), suggesting a dose-response relationship. These results indicate that n-3 LCPUFA may have immuno-stimulating effects...