Research Topics
| Michael TimmSummaryAffiliation: University of Copenhagen Country: Denmark Publications
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Publications
Immunomodulatory effects of honey cannot be distinguished from endotoxinMichael Timm
Department of Pharmacology and Pharmacotherapy, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, DK 2100 Copenhagen, Denmark
Cytokine 42:113-20. 2008..We speculate that the observed in vitro immunomodulatory effects of honey might solely be explained by the endotoxin content in the natural honeys...
Cryopreservation of differentiated HL-60 cells for pyrogen testingMichael Timm
Department of Pharmacology and Pharmacotherapy, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, DK 2100 Copenhagen, Denmark
J Immunol Methods 339:146-52. 2008..In conclusion, ATRA differentiated HL-60 cells are cryopreservable and retain reactivity upon thawing. It is therefore possible to produce an in-vitro in-house pyrogen test kit for medicines and related products...
Assessment of the total inflammatory potential of bioaerosols by using a granulocyte assayMichael Timm
Department of Pharmacology and Pharmacotherapy, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, DK 2100 Copenhagen, Denmark
Appl Environ Microbiol 75:7655-62. 2009..Therefore, potential occupational health effects related to inflammation of the airways in a working environment can be estimated using this assay...
Immunomodulatory effects of testosterone evaluated in all-trans retinoic acid differentiated HL-60 cells, granulocytes, and monocytesAlex Boje
Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark
Int Immunopharmacol 12:573-9. 2012..Testosterone, at pharmacological doses, was also shown to suppress generation of reactive oxygen species and interleukin-8 in human granulocytes and monocytes, respectively, to a similar extent as observed in differentiated HL-60 cells...
Effect of moist heat sterilisation on the pyrogenicity of cell wall components from Staphylococcus aureusLise Moesby
Department of Pharmacology and Pharmacotherapy, Faculty of Pharmaceutical Sciences, University of Copenhagen, 2 Universitetsparken, DK 2100 Copenhagen, Denmark
Eur J Pharm Sci 35:442-6. 2008..In conclusion the terminal moist heat sterilisation procedures described by the European Pharmacopoeia are not able to inactivate the interleukin-6 inducing activity of S. aureus lipoteichoic acid and peptidoglycan...
Utilization of the human cell line HL-60 for chemiluminescence based detection of microorganisms and related substancesMichael Timm
Department of Pharmacology, The Danish University of Pharmaceutical Sciences, Universitetsparken 2, 2100 Copenhagen, Denmark
Eur J Pharm Sci 27:252-8. 2006..Furthermore, the utilization of the assay for pyrogenic examination of recombinant drugs derived from yeast expression systems would be relevant to examine...
The effect of dietary fish oil-supplementation to healthy young men on oxidative burst measured by whole blood chemiluminescenceStine Bartelt
Department of Human Nutrition, Faculty of Life Sciences, University of Copenhagen, Rolighedsvej 30, DK 1958 Frederiksberg C, Denmark
Br J Nutr 99:1230-8. 2008..44, P = 0.016), suggesting a dose-response relationship. These results indicate that n-3 LCPUFA may have immuno-stimulating effects...
