P Svensson

Summary

Affiliation: University of Aarhus
Country: Denmark

Publications

  1. ncbi request reprint Effect of muscle relaxants on experimental jaw-muscle pain and jaw-stretch reflexes: a double-blind and placebo-controlled trial
    Peter Svensson
    Department of Clinical Oral Physiology, Dental School, Aarhus University, DK 8000 Aarhus C, Denmark
    Eur J Pain 7:449-56. 2003
  2. ncbi request reprint Muscle pain in the head: overlap between temporomandibular disorders and tension-type headaches
    Peter Svensson
    Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus, Denmark
    Curr Opin Neurol 20:320-5. 2007
  3. ncbi request reprint What can human experimental pain models teach us about clinical TMD?
    Peter Svensson
    Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus, Vennelyst Boulevard 9, DK 8000 Aarhus C, Denmark
    Arch Oral Biol 52:391-4. 2007
  4. ncbi request reprint Glutamate-evoked pain and mechanical allodynia in the human masseter muscle
    Peter Svensson
    Department of Clinical Oral Physiology, Dental School, Aarhus University, DK 8000 Aarhus C, Denmark
    Pain 101:221-7. 2003
  5. ncbi request reprint One hour of tongue-task training is associated with plasticity in corticomotor control of the human tongue musculature
    P Svensson
    Center for Sensory Motor Interaction, Orofacial Pain Laboratory, Aalborg University, Aalborg, Denmark
    Exp Brain Res 173:165-73. 2006
  6. ncbi request reprint Plasticity in corticomotor control of the human tongue musculature induced by tongue-task training
    Peter Svensson
    Orofacial Pain Laboratory, Center for Sensory Motor Interaction, Aalborg University, Aalborg, Denmark
    Exp Brain Res 152:42-51. 2003
  7. ncbi request reprint Injection of nerve growth factor into human masseter muscle evokes long-lasting mechanical allodynia and hyperalgesia
    Peter Svensson
    Department of Clinical Oral Physiology, Dental School, University of Aarhus, Vennelyst Boulevard 9, DK 8000 Aarhus C, Denmark
    Pain 104:241-7. 2003
  8. ncbi request reprint Pain effects of glutamate injections into human jaw or neck muscles
    Peter Svensson
    Department of Clinical Oral Physiology, Royal Dental College, University of Aarhus, Aarhus, Denmark
    J Orofac Pain 19:109-18. 2005
  9. ncbi request reprint Overview on tools and methods to assess neuropathic trigeminal pain
    Peter Svensson
    Department of Clinical Oral Physiology, Royal Dental College, University of Aarhus, Aarhus, Denmark
    J Orofac Pain 18:332-8. 2004
  10. ncbi request reprint Associations between pain and neuromuscular activity in the human jaw and neck muscles
    Peter Svensson
    Center for Sensory Motor Interaction, Orofacial Pain Laboratory, Aalborg University, DK 9220 Aalborg, Denmark
    Pain 109:225-32. 2004

Collaborators

Detail Information

Publications139 found, 100 shown here

  1. ncbi request reprint Effect of muscle relaxants on experimental jaw-muscle pain and jaw-stretch reflexes: a double-blind and placebo-controlled trial
    Peter Svensson
    Department of Clinical Oral Physiology, Dental School, Aarhus University, DK 8000 Aarhus C, Denmark
    Eur J Pain 7:449-56. 2003
    ..034). In conclusion, tolperisone hydrochloride provides a small, albeit significant reduction in the perceived intensity of experimental jaw-muscle pain whereas the present dose had no effect on the short-latency jaw-stretch reflex...
  2. ncbi request reprint Muscle pain in the head: overlap between temporomandibular disorders and tension-type headaches
    Peter Svensson
    Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus, Denmark
    Curr Opin Neurol 20:320-5. 2007
    ..It still unclear, however, to what extent these two prevalent disorders are separate entities or have similar pathophysiological background...
  3. ncbi request reprint What can human experimental pain models teach us about clinical TMD?
    Peter Svensson
    Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus, Vennelyst Boulevard 9, DK 8000 Aarhus C, Denmark
    Arch Oral Biol 52:391-4. 2007
    ....
  4. ncbi request reprint Glutamate-evoked pain and mechanical allodynia in the human masseter muscle
    Peter Svensson
    Department of Clinical Oral Physiology, Dental School, Aarhus University, DK 8000 Aarhus C, Denmark
    Pain 101:221-7. 2003
    ..The present results suggest that injection of 1.0M glutamate into the masseter muscle may provide a useful experimental method to test sensitization and efficacy of peripheral EAA receptor antagonists in human subjects...
  5. ncbi request reprint One hour of tongue-task training is associated with plasticity in corticomotor control of the human tongue musculature
    P Svensson
    Center for Sensory Motor Interaction, Orofacial Pain Laboratory, Aalborg University, Aalborg, Denmark
    Exp Brain Res 173:165-73. 2006
    ....
  6. ncbi request reprint Plasticity in corticomotor control of the human tongue musculature induced by tongue-task training
    Peter Svensson
    Orofacial Pain Laboratory, Center for Sensory Motor Interaction, Aalborg University, Aalborg, Denmark
    Exp Brain Res 152:42-51. 2003
    ..The present findings suggest that a specific and reversible plasticity of the corticomotor excitability related to tongue muscle control can be induced when humans learn to perform successfully a novel tongue task...
  7. ncbi request reprint Injection of nerve growth factor into human masseter muscle evokes long-lasting mechanical allodynia and hyperalgesia
    Peter Svensson
    Department of Clinical Oral Physiology, Dental School, University of Aarhus, Vennelyst Boulevard 9, DK 8000 Aarhus C, Denmark
    Pain 104:241-7. 2003
    ..The present pain model is safe and may be used to gain further insight into the neurobiological mechanisms of muscle pain and sensitization...
  8. ncbi request reprint Pain effects of glutamate injections into human jaw or neck muscles
    Peter Svensson
    Department of Clinical Oral Physiology, Royal Dental College, University of Aarhus, Aarhus, Denmark
    J Orofac Pain 19:109-18. 2005
    ....
  9. ncbi request reprint Overview on tools and methods to assess neuropathic trigeminal pain
    Peter Svensson
    Department of Clinical Oral Physiology, Royal Dental College, University of Aarhus, Aarhus, Denmark
    J Orofac Pain 18:332-8. 2004
    ..There is also a need for common guidelines on classification, diagnostic procedures, and management. This will require concerted international, interdisciplinary action...
  10. ncbi request reprint Associations between pain and neuromuscular activity in the human jaw and neck muscles
    Peter Svensson
    Center for Sensory Motor Interaction, Orofacial Pain Laboratory, Aalborg University, DK 9220 Aalborg, Denmark
    Pain 109:225-32. 2004
    ..In conclusion, experimental neck pain is not associated with tonic increases in jaw EMG activity although jaw muscle pain can be linked to increases in neck EMG activity with the head and jaw at rest...
  11. ncbi request reprint Spread and referral of experimental pain in different jaw muscles
    Peter Svensson
    Department of Clinical Oral Physiology, Royal Dental College, University of Aarhus, Vennelyst Boulevard 9, DK 8000 Aarhus C, Denmark
    J Orofac Pain 17:214-23. 2003
    ..To test the hypothesis that there would be no differences in perceived pain intensity and spread and referral of pain evoked by injection of a similar amount of hypertonic saline into 6 different jaw-muscle sites in healthy female subjects...
  12. doi request reprint Guidelines and recommendations for assessment of somatosensory function in oro-facial pain conditions--a taskforce report
    P Svensson
    Department of Clinical Oral Physiology, Aarhus University, Aarhus, Denmark
    J Oral Rehabil 38:366-94. 2011
    ....
  13. doi request reprint Relationships between craniofacial pain and bruxism
    P Svensson
    Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus, Aarhus C, Denmark
    J Oral Rehabil 35:524-47. 2008
    ..The review will enable clinicians to understand the reasons why simple cause-effect relationships between bruxism and craniofacial pain are inadequate and the current implications for management of craniofacial pain...
  14. doi request reprint Effects of NGF-induced muscle sensitization on proprioception and nociception
    Peter Svensson
    Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus, Vennelyst Boulevard 9, 8000 Aarhus C, Denmark
    Exp Brain Res 189:1-10. 2008
    ..Additional challenge of the NGF pretreated muscle with glutamate did not indicate a conspicuous sensitization to noxious chemical stimuli. These findings are discussed in terms of the concept of "proprioceptive allodynia"...
  15. ncbi request reprint Suppression of motor evoked potentials in a hand muscle following prolonged painful stimulation
    Peter Svensson
    Department of Clinical Oral Physiology, Dental School, University of Aarhus Denmark, Vennelyst Boulevard 9, DK 8000 Aarhus, Denmark
    Eur J Pain 7:55-62. 2003
    ..Hence, painful stimulation differs from non-painful, repetitive stimulation, which facilitates the corticomotor pathway...
  16. ncbi request reprint Nerve growth factor-evoked masseter muscle sensitization and perturbation of jaw motor function in healthy women
    Peter Svensson
    Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus
    J Orofac Pain 22:340-8. 2008
    ..Combined these data would indicate if injection of NGF into the masseter muscle is a valid model of muscle pain related to temporomandibular disorders (TMD)...
  17. doi request reprint Quantitative sensory tests before and 1(1/2) years after orthognathic surgery: a cross-sectional study
    L Baad-Hansen
    Department of Clinical Oral Physiology, School of Dentistry, Aarhus University, Aarhus, Denmark
    J Oral Rehabil 37:313-21. 2010
    ..Pre-op patients showed minor somatosensory changes. In addition to patients serving as their own control in prospective studies, a healthy control group and extratrigeminal control sites should be included in future studies...
  18. ncbi request reprint The relationship between selective sleep deprivation, nocturnal jaw-muscle activity and pain in healthy men
    T Arima
    Orofacial Pain Laboratory, Center for Sensory-Motor Interaction, Aalborg University, Denmark
    J Oral Rehabil 28:140-8. 2001
    ..These results suggest that deprivation of SWS may not interact immediately with nocturnal jaw-muscle activity and jaw-muscle pain...
  19. ncbi request reprint Effects of intra-articular ketamine on pain and somatosensory function in temporomandibular joint arthralgia patients
    Emad E Ayesh
    Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus, Vennelyst Boulevard 9, DK 8000 Aarhus, Denmark
    Pain 137:286-94. 2008
    ..In conclusion, there appears to be no rationale to use intra-articular ketamine injections in TMJ arthralgia patients, and peripheral NMDA receptors may play a minor role in the pathophysiology of this disorder...
  20. doi request reprint Interactions of glutamate and capsaicin-evoked muscle pain on jaw motor functions of men
    K Wang
    Center for Sensory Motor Interaction, Orofacial Pain Laboratory, Aalborg University, DK 9220 Aalborg, Denmark
    Clin Neurophysiol 121:950-6. 2010
    ..The aim of the study was to investigate the interaction between glutamate and capsaicin-evoked muscle pain on human jaw motor functions...
  21. doi request reprint Effect of stimulus parameters and contraction level on inhibitory responses in human jaw-closing muscles: Implications for contingent stimulation
    F Jadidi
    Department of Clinical Oral Physiology, University of Aarhus, Denmark
    Arch Oral Biol 54:1075-82. 2009
    ..Examine the effect of stimulus duration, intensity and level of muscle contraction on the inhibitory responses evoked by electrical stimuli in human jaw-closing muscles applied to the right mental nerve...
  22. ncbi request reprint Excitatory actions of experimental muscle pain on early and late components of human jaw stretch reflexes
    K Wang
    Center for Sensory--Motor Interaction, Orofacial Pain Laboratory, Aalborg University, Fredrik Bajers Vej 7 D-3, DK-9220 Aalborg S, Denmark
    Arch Oral Biol 46:433-42. 2001
    ..A change in the sensitivity of the fusimotor system during muscle pain is suggested as an explanation...
  23. ncbi request reprint Experimental jaw-muscle pain does not change heteronymous H-reflexes in the human temporalis muscle
    P Svensson
    Center for Sensory Motor Interaction, Orofacial Pain Laboratory, Aalborg University, Denmark
    Exp Brain Res 121:311-8. 1998
    ..2 ms). These reflex responses did not show a systematic change during the pain conditions. In conclusion, acute contralateral jaw-muscle pain does not seem to modulate the motoneuron excitability as measured by the heteronymous H-reflex...
  24. ncbi request reprint Effect of pinching-evoked pain on jaw-stretch reflexes and exteroceptive suppression periods in healthy subjects
    A Biasiotta
    Center for Sensory Motor Interaction, Orofacial Pain Laboratory, Aalborg University, Fredrik Bajars Vej 7D 3, 9220 Aalborg, Denmark
    Clin Neurophysiol 118:2180-8. 2007
    ..To investigate the influence of conditioning cutaneous nociceptive inputs by a new "pinch" model on the jaw-stretch reflex and the exteroceptive suppression periods (ES1 and ES2) in jaw muscles...
  25. ncbi request reprint Hypersensitivity to mechanical and intra-articular electrical stimuli in persons with painful temporomandibular joints
    E E Ayesh
    Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus, Vennelyst Boulevard 9, DK 8000 Aarhus C, Denmark
    J Dent Res 86:1187-92. 2007
    ..This study provides new evidence of sensitization of the TMJs as well as central nociceptive pathways. QST may facilitate a mechanism-based classification of temporomandibular disorders...
  26. ncbi request reprint Muscle pain modulates mastication: an experimental study in humans
    P Svensson
    Center for Sensory Motor Interaction, Aalborg University, Denmark
    J Orofac Pain 12:7-16. 1998
    ..Significant changes in jaw movements during painful mastication could not be detected with the present jaw-tracking device, but further studies with more accurate and sensitive devices are needed...
  27. ncbi request reprint Experimental human muscle pain and muscular hyperalgesia induced by combinations of serotonin and bradykinin
    V Babenko
    Center for Sensory Motor Interaction, Laboratory for Experimental Pain Research, Aalborg University, Aalborg E, Denmark
    Pain 82:1-8. 1999
    ..Pre-treatment with serotonin may enhance the effect of bradykinin in the generation of muscle pain and muscular hyperalgesia in humans...
  28. ncbi request reprint Duration and distribution of experimental muscle hyperalgesia in humans following combined infusions of serotonin and bradykinin
    V Babenko
    Center for Sensory Motor Interaction, Laboratory for Experimental Pain Research, Aalborg University, Fredrik Bajers Vej 7D 3, DK 9220, Aalborg, Denmark
    Brain Res 853:275-81. 2000
    ..No widespread hyperalgesia to the ankle and other leg (tested at 10 cm below the patella and ankle) was observed suggesting a predominant peripheral origin of the experimentally induced hyperalgesic stage...
  29. ncbi request reprint Different EEG topographic effects of painful and non-painful intramuscular stimulation in man
    P F Chang
    Human Brain Mapping and Cortical Imaging Laboratory, Center for Sensory Motor Interaction, Aalborg University, Fredrik Bajers Vej 7 D 3, 9220 Aalborg, Denmark
    Exp Brain Res 141:195-203. 2001
    ....
  30. ncbi request reprint Influence of sensory deprivation and perturbation of trigeminal afferent fibers on corticomotor control of human tongue musculature
    L Halkjaer
    Department of Orthodontics, School of Dentistry, University of Aarhus, Aarhus, Denmark
    Exp Brain Res 170:199-205. 2006
    ....
  31. ncbi request reprint Somatosensory function following painful repetitive electrical stimulation of the human temporomandibular joint and skin
    E E Ayesh
    Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus, Vennelyst Boulevard 9, 8000, Aarhus C, Denmark
    Exp Brain Res 179:415-25. 2007
    ..Further studies will examine the somatosensory sensitivity of patients with TMJ pain problems...
  32. pmc Interactions between glutamate and capsaicin in inducing muscle pain and sensitization in humans
    L Arendt-Nielsen
    Center for Sensory Motor Interaction, Orofacial Pain Laboratory, Aalborg University, DK 9220 Aalborg, Denmark
    Eur J Pain 12:661-70. 2008
    ..These findings support previous animal data...
  33. ncbi request reprint Capsaicin-induced muscle pain alters the excitability of the human jaw-stretch reflex
    K Wang
    Center for Sensory Motor Interaction, Orofacial Pain Laboratory, Aalborg University, Fredrik Bajers Vej 7 D 3, Denmark
    J Dent Res 81:650-4. 2002
    ..Increased sensitivity of the fusimotor system during acute muscle pain could be one likely mechanism to explain the findings...
  34. ncbi request reprint Influence of methodological parameters on human jaw-stretch reflexes
    K Wang
    Center for Sensory-Motor Interaction, Orofacial Pain Laboratory, Aalborg University, Denmark
    Eur J Oral Sci 109:86-94. 2001
    ..However, different biting positions on the bars of the stretch device significantly influenced the amplitude of the stretch reflex...
  35. ncbi request reprint Modulation of an inhibitory reflex in single motor units in human masseter by tonic painful stimulation
    P Svensson
    Center for Sensory Motor Interaction, Orofacial Pain Laboratory, Aalborg University, Fredrik Bajers Vej 7D 3, DK 9220, Aalborg, Denmark
    Pain 83:441-6. 1999
    ..In conclusion, this study indicates that tonic masseter pain has a net excitatory effect on the inhibitory jaw-reflexes, which could be mediated by presynaptic mechanisms on the involved motoneurons...
  36. pmc The hypoalgesic effect of 3-D video glasses on cold pressor pain: reproducibility and importance of information
    B Bentsen
    Department of Oral Radiology, Royal Dental College, University of Aarhus, Vennelyst Boulevard, DK 8000 Arhus C, Denmark
    Anesth Prog 47:67-71. 2000
    ..After 4 weeks, the study was repeated, and there were no significant changes in the effect of video glasses. The median visual analogue scale scores were reduced in both the video and the control trials compared with the first session...
  37. ncbi request reprint Reduction of clinical temporomandibular joint pain is associated with a reduction of the jaw-stretch reflex
    Kelun Wang
    Orofacial Pain Laboratory, Center for Sensory Motor Interaction, Aalborg University, Aalborg, Denmark
    J Orofac Pain 18:33-40. 2004
    ....
  38. ncbi request reprint Effect of experimental posterior temporalis muscle pain on human brainstem reflexes
    Anitha Peddireddy
    Orofacial Pain Laboratory, Center for Sensory Motor Interaction, Aalborg University, Fredrik Bajars Vej 7D 3, 9220 Aalborg, Denmark
    Clin Neurophysiol 116:1611-20. 2005
    ..To study the modulation of jaw-stretch and blink reflexes by experimental posterior temporalis muscle pain...
  39. ncbi request reprint Intramuscular and intradermal injection of capsaicin: a comparison of local and referred pain
    N Witting
    Department of Neurology and Danish Pain Research Center, Aarhus University Hospital, Building 1C, Noerrebrogade 44, DK 8000, Aarhus, Denmark
    Pain 84:407-12. 2000
    ..The model with identical noxious stimulation of muscle and skin may be suitable for the study of differences in deep and superficial pain as seen in the clinic...
  40. ncbi request reprint Brain dynamics of scalp evoked potentials and current source densities to repetitive (5-pulse train) painful stimulation of skin and muscle: central correlate of temporal summation
    A C Chen
    Human Brain Mapping and Cortical Imaging Laboratory, Center for Sensory Motor Interaction, Aalborg University, Denmark
    Brain Topogr 13:59-72. 2000
    ..This change in "rapid cortical dynamics" of short-term plasticity could be an important mechanism for wind-up and pain processing in the brain...
  41. doi request reprint Stretch reflex and pressure pain thresholds in chronic tension-type headache patients and healthy controls
    A Peddireddy
    Orofacial Pain Laboratory, Centre for Sensory Motor Interaction, Aalborg University, Aalborg, Denmark
    Cephalalgia 29:556-65. 2009
    ..509), whereas women showed significantly lower PPT measurements (P < 0.046). The results demonstrated a facilitation of the stretch reflex pathways in CTTH patients that is unrelated to measures of pericranial sensitivity...
  42. ncbi request reprint Fatigue and pain in human jaw muscles during a sustained, low-intensity clenching task
    P Svensson
    Department of Prosthetic Dentistry and Stomatognathic Physiology, Royal Dental College, University of Aarhus, Aarhus, Denmark
    Arch Oral Biol 46:773-7. 2001
    ..These findings demonstrate that a sustained, low-intensity clenching task can induce subjective and electrophysiological indications of fatigue...
  43. ncbi request reprint Effect of jaw muscle pain and soreness evoked by capsaicin before sleep on orofacial motor activity during sleep
    T Arima
    Orofacial Pain Laboratory, Center for Sensory-Motor Interaction, Aalborg University, Fredrik Bajersvej 7 D-3, DK-9220 Aalborg, Denmark
    J Orofac Pain 15:245-56. 2001
    ....
  44. ncbi request reprint Effect of clenching levels on heteronymous H-reflex in human temporalis muscle
    P Svensson
    Orofacial Pain Laboratory, Center for Sensory Motor Interaction, Aalborg University, Aalborg S, Denmark
    Exp Brain Res 126:467-72. 1999
    ..008). These data indicate that the heteronymous H-reflex can be reliably elicited by means of an automatic system for stimulus delivery and that the amplitude of the H-reflex is dependent on the preceding activity of the motoneuron pool...
  45. pmc The effect of a new type of video glasses on the perceived intensity of pain and unpleasantness evoked by a cold pressor test
    B Bentsen
    University of Aarhus Denmark, Royal Dental College, Department of Oral Radiology, Vennelyst Boulevard 8, DK 8000 Arhus C, Denmark
    Anesth Prog 46:113-7. 1999
    ..05). This suggests that the use of distraction by means of video glasses is able to reduce the perceived intensity of pain and unpleasantness...
  46. ncbi request reprint Differential effect of painful heterotopic stimulation on capsaicin-induced pain and allodynia
    N Witting
    Department of Neurology, Aarhus University Hospital, Aarhus, Denmark
    Brain Res 801:206-10. 1998
    ..The observed differential effect on the magnitude of pain and hyperalgesia on the one hand and area of hyperalgesia on the other suggests that the DNIC effect on spinal activity is selective and not general...
  47. ncbi request reprint Experimental muscle pain increases the human stretch reflex
    D A Matre
    Center for Sensory Motor Interaction, Aalborg University, Denmark
    Pain 75:331-9. 1998
    ..However, the data could not support the vicious cycle model because the excitability of the alpha-motoneurone pool was unchanged...
  48. ncbi request reprint Quantification of local and referred muscle pain in humans after sequential i.m. injections of hypertonic saline
    T Graven-Nielsen
    Center for Sensory Motor Interaction, Aalborg University, Denmark
    Pain 69:111-7. 1997
    ..64, P < 0.0001, n = 231) and referred (R = 0.47, P < 0.0001, n = 231) pain areas. Based on the above results it can be concluded that experimental muscle pain is influenced by temporal and spatial summation...
  49. doi request reprint Does eccentric-exercise-induced jaw muscle soreness influence brainstem reflexes?
    Tetsurou Torisu
    Center for Sensory Motor Interaction SMI, Laboratory for Human Experimental Pain Research, Aalborg University, Fredrik Bajers Vej 7 D 3, DK 9220 Aalborg, Denmark
    Clin Neurophysiol 119:2819-28. 2008
    ....
  50. ncbi request reprint Craniofacial muscle pain: review of mechanisms and clinical manifestations
    P Svensson
    Center for Sensory Motor Interaction, Aalborg University, Fredrik Bajers Vej 7D 3, DK 9220 Aalborg E, Denmark
    J Orofac Pain 15:117-45. 2001
    ..Changes in somatosensory and motor function may therefore be viewed as consequences of pain and not factors leading to pain. Implications for the diagnosis and management of persistent muscle pain are discussed from this perspective...
  51. ncbi request reprint Glutamate evoked neck and jaw muscle pain facilitate the human jaw stretch reflex
    K Wang
    Center for Sensory Motor Interaction, Orofacial Pain Laboratory, Aalborg University, Fredrik Bajers Vej 7 D 3, DK 9220 Aalborg E, Denmark
    Clin Neurophysiol 115:1288-95. 2004
    ..The aim of the present study was to test the effects of glutamate-evoked jaw or neck muscle pain on the jaw stretch reflex recorded in both jaw and neck muscles...
  52. doi request reprint Effects of different stimulus locations on inhibitory responses in human jaw-closing muscles
    F Jadidi
    Department of Clinical Oral Physiology, School of Dentistry, Aarhus University, Aarhus, Denmark
    J Oral Rehabil 38:487-500. 2011
    ....
  53. ncbi request reprint Mechanical hyperesthesia of human facial skin induced by tonic painful stimulation of jaw muscles
    P Svensson
    Center for Sensory Motor Interaction, Aalborg University, Denmark
    Pain 74:93-100. 1998
    ..Similar hyperexcitability changes may be part of the pathophysiological mechanisms involved in painful temporomandibular disorders...
  54. ncbi request reprint Experimentally induced muscle pain induces hypoalgesia in heterotopic deep tissues, but not in homotopic deep tissues
    T Graven-Nielsen
    Center for Sensory Motor Interaction, Laboratory for Experimental Pain Research, Aalborg University, Aalborg, Denmark
    Brain Res 787:203-10. 1998
    ..Thus, a pathologically disturbed inhibitory mechanism may result in widespread deep hyperalgesia in muscle pain patients...
  55. ncbi request reprint Modulation of stretch-evoked reflexes in single motor units in human masseter muscle by experimental pain
    P Svensson
    Center for Sensory Motor Interaction, Orofacial Pain Laboratory, Aalborg University, Denmark
    Exp Brain Res 132:65-71. 2000
    ..It is concluded that the most likely explanation for the reduced reflex response of low-threshold masseter motor units during experimental pain is a tonic reduction in the fusimotor drive to the masseter spindles...
  56. ncbi request reprint Quantitative analysis of reflex inhibition in single motor units in human masseter muscle: effects of stimulus intensity
    T Graven-Nielsen
    Center for Sensory Motor Interaction, Laboratory for Experimental Pain Research, Aalborg University, Fredrik Bajers Vej 7D 3, DK 9220 Aalborg E, Denmark
    Muscle Nerve 23:259-66. 2000
    ..The methods used in the present study provide a useful means of quantifying the effects of motoneuron excitability in detail...
  57. ncbi request reprint Assessment of nociceptive trigeminal pathways by laser-evoked potentials and laser silent periods in patients with painful temporomandibular disorders
    A Romaniello
    Center for Sensory Motor Interaction, Orofacial Pain Laboratory, Aalborg University, Aalborg, Denmark
    Pain 103:31-9. 2003
    ..These findings are consistent with recent experimental pain studies and suggest that chronic craniofacial pain in TMD patients may be associated with a dysfunction of the trigeminal nociceptive system...
  58. ncbi request reprint Effect of low-level clenching and subsequent muscle pain on exteroceptive suppression and resting muscle activity in human jaw muscles
    Tetsurou Torisu
    Center for Sensory Motor Interaction, Laboratory for Human Experimental Pain Research, Aalborg University, Fredrik Bajers Vej 7 D 3, DK 9220, Aalborg, Denmark
    Clin Neurophysiol 118:999-1009. 2007
    ....
  59. doi request reprint Blink reflexes in chronic tension-type headache patients and healthy controls
    Anitha Peddireddy
    Orofacial Pain Laboratory, Center for Sensory Motor Interaction, Aalborg University, Denmark
    Clin Neurophysiol 120:1711-6. 2009
    ..To use the R2 component of nociceptive-specific blink reflex (nBR) to probe the trigeminal nociceptive system and compare chronic tension-type headache (CTTH) patients and healthy controls...
  60. doi request reprint Effects of eccentric jaw exercise on temporal summation in jaw-closing muscles of healthy subjects
    Tetsurou Torisu
    Center for Sensory Motor Interaction, Aalborg University, Fredrik Bajers Vej 7 D 3, DK 9220 Aalborg, Denmark
    Eur J Pain 14:719-24. 2010
    ..The present findings demonstrate that eccentric jaw exercise does not induce detectable changes in temporal summation. However, the summation ratio may have clinical utility to differentiate the location of sensitization...
  61. ncbi request reprint Effects of local and remote muscle pain on human jaw reflexes evoked by fast stretches at different clenching levels
    P Svensson
    Orofacial Pain Laboratory, Center for Sensory Motor Interaction, Aalborg University, Denmark
    Exp Brain Res 139:495-502. 2001
    ..Local circuits at the trigeminal level involving the fusimotor system are proposed to mediate a significant part of this modulatory effect...
  62. ncbi request reprint Analysis of stimulus-evoked pain in patients with myofascial temporomandibular pain disorders
    P Svensson
    Center for Sensory Motor Interaction, Orofacial Pain Laboratory, Aalborg University, Aalborg, Denmark
    Pain 92:399-409. 2001
    ..These findings suggest that myofascial TMD pain is associated with a facilitation of stimulus-evoked pain primarily, but not exclusively related to the painful region...
  63. ncbi request reprint Topographic effects of tonic cutaneous nociceptive stimulation on human electroencephalograph
    P F Chang
    Human Brain Mapping and Cortical Imaging Laboratory, Center for Sensory-Motor Interaction, Aalborg University, Fredrik Bajers Vej 7 D-3 DK-9220, Aalborg, Denmark
    Neurosci Lett 305:49-52. 2001
    ..This implicates that the observed topographic EEG activation is not specific for pain but probably related to the cutaneous stimulation...
  64. ncbi request reprint Effect of a nociceptive trigeminal inhibitory splint on electromyographic activity in jaw closing muscles during sleep
    L Baad-Hansen
    Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus, Aarhus C, Denmark
    J Oral Rehabil 34:105-11. 2007
    ..However, the EMG-activity was not directly related to clinical outcome. Further studies will be needed to determine long-term effects and possible side effects of the NTI splint...
  65. ncbi request reprint Quantification of deep and superficial sensibility in saline-induced muscle pain--a psychophysical study
    T Graven-Nielsen
    Center for Sensory Motor Interaction, Laboratory for Experimental Pain Research, Aalborg University, Denmark
    Somatosens Mot Res 15:46-53. 1998
    ..The present placebo-controlled experiments failed to show muscular or subcutaneous hyperalgesia after saline-induced muscle pain per se...
  66. ncbi request reprint Effects of experimental muscle pain on mechanical properties of single motor units in human masseter
    M K Sohn
    Center for Sensory Motor Interaction, Aalborg University, DK 9220 Aalborg, Denmark
    Clin Neurophysiol 115:76-84. 2004
    ..Therefore, the objective of the present study was to measure the mechanical properties of SMU in the masseter to clarify the mechanism which underlies the decrease in SMU firing rate during jaw-muscle pain...
  67. doi request reprint Effect of conditioning electrical stimuli on temporalis electromyographic activity during sleep
    F Jadidi
    Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus, Aarhus, Denmark
    J Oral Rehabil 35:171-83. 2008
    ..The present study suggests that biofeedback with electrical pulses does not cause major disruption in sleep and is associated with pronounced reduction in temporalis EMG activity during sleep...
  68. ncbi request reprint Modulation of trigeminal laser evoked potentials and laser silent periods by homotopical experimental pain
    Antonietta Romaniello
    Orofacial Pain Laboratory, Center for Sensory Motor Interaction, Aalborg University, Fredrik Bajers Vej 7, D 3, DK 9220 Aalborg, Denmark
    Pain 98:217-28. 2002
    ..These effects could be mediated through the activation of segmental and suprasegmental inhibitory systems that may function interdependently...
  69. ncbi request reprint Ketamine attenuates glutamate-induced mechanical sensitization of the masseter muscle in human males
    Brian E Cairns
    Orofacial Pain Laboratory, Center for Sensory Motor Interaction, Aalborg University, 9220 Aalborg, Denmark
    Exp Brain Res 169:467-72. 2006
    ..The attenuation of glutamate-induced mechanical sensitization by ketamine suggests that this effect is mediated, in part, through activation of peripheral NMDA receptors...
  70. ncbi request reprint Spatial and temporal assessment of orofacial somatosensory sensitivity: a methodological study
    Torben H Thygesen
    Department of Oral and Maxillofacial Surgery Aarhus University Hospital Noerrebrogade 44, Aarhus C, Denmark
    J Orofac Pain 21:19-28. 2007
    ..To evaluate the sensitivity and reproducibility of a multimodal psychophysical technique for the assessment of both spatial and temporal changes in somatosensory function after an infraorbital nerve block...
  71. ncbi request reprint Temporomandibular disorders after whiplash injury: a controlled, prospective study
    Helge Kasch
    Department of Neurology, Aarhus University Hospital, Danish Pain Research Center, Aarhus University, Noerrebrogade 44, Building 1C, DK 8000 Aarhus C, Denmark
    J Orofac Pain 16:118-28. 2002
    ..The aim of the present study was to assess pain and sensorimotor function in the craniofacial region in an unselected group of patients sustaining a motor vehicle accident involving a rear collision...
  72. ncbi request reprint Painful conditioning stimuli of the craniofacial region evokes diffuse noxious inhibitory controls in men and women
    Kelun Wang
    Center for Sensory Motor Interaction, Orofacial Pain Laboratory, Aalborg University, Department of Oral and Maxillofacial Surgery, Aalborg Hospital, Aalborg, Denmark
    J Orofac Pain 24:255-61. 2010
    ..To compare the modulatory effects of tonic mechanical or thermal craniofacial painful conditioning stimuli on pain sensitivity in craniofacial and spinal test sites in healthy men and women...
  73. ncbi request reprint Conditioning of the masseter inhibitory reflex by homotopically applied painful heat in humans
    O K Andersen
    Center for Sensory Motor Interaction, Aalborg University, Denmark
    Electroencephalogr Clin Neurophysiol 109:508-14. 1998
    ....
  74. ncbi request reprint The influence of low back pain on muscle activity and coordination during gait: a clinical and experimental study
    L Arendt-Nielsen
    Laboratory for Experimental Pain Research, Aalborg University, Denmark
    Pain 64:231-40. 1996
    ..New possibilities to monitor and investigate altered motor performance may help to develop more rational therapies for CLBP patients...
  75. ncbi request reprint Effects of muscle fatigue induced by low-level clenching on experimental muscle pain and resting jaw muscle activity: gender differences
    Tetsurou Torisu
    Center for Sensory Motor Interaction, Laboratory for Human Experimental Pain Research, Aalborg University, Fredrik Bajers Vej 7 D 3, 9220 Aalborg, Denmark
    Exp Brain Res 174:566-74. 2006
    ..The present findings provide new information on the complex influence of gender on sensory-motor integration in the trigeminal system which may contribute to differences in susceptibility to develop musculoskeletal pain problems...
  76. ncbi request reprint Influence of jaw gape on EMG of jaw muscles and jaw-stretch reflexes
    Kelun Wang
    Center for Sensory Motor Interaction, Orofacial Pain Laboratory, Aalborg University, Denmark
    Arch Oral Biol 52:562-70. 2007
    ..013). It is concluded that the jaw gapes influence the sensitivity of the human muscle spindle afferents in jaw-closing muscles with a distinct peak, which is within normal jaw gapes during function...
  77. doi request reprint Human nerve growth factor sensitizes masseter muscle nociceptors in female rats
    Peter Svensson
    Department of Clinical Oral Physiology, School of Dentistry, Faculty of Health Sciences, University of Aarhus, DK 8000 Aarhus C, Denmark
    Pain 148:473-80. 2010
    ..These findings indicate that human NGF-induced sensitization of masseter nociceptors results, in part, from the activation of TrkA receptors, but does not appear to be mediated through enhanced peripheral NMDA receptor activity...
  78. ncbi request reprint Influence of age and gender on the jaw-stretch and blink reflexes
    Anitha Peddireddy
    Orofacial Pain Laboratory, Center for Sensory Motor Interaction, Aalborg University, Fredrik Bajars Vej 7D 3, Aalborg, Denmark
    Exp Brain Res 171:530-40. 2006
    ....
  79. ncbi request reprint Opioid-insensitive hypoalgesia to mechanical stimuli at sites ipsilateral and contralateral to experimental muscle pain in human volunteers
    Thomas Graven-Nielsen
    Center for Sensory Motor Interaction, Laboratory for Experimental Pain Research, Aalborg University, Fredrik Bajers Vej 7D 3, 9220 Aalborg E, Denmark
    Exp Brain Res 146:213-22. 2002
    ..The deep peroneal nerve specifically innervates both the TA muscle and the only site of hyperalgesia indicating spatial summation of afferent activity from these structures...
  80. ncbi request reprint Association between temporomandibular joint symptoms, signs, and clinical diagnosis using the RDC/TMD and radiographic findings in temporomandibular joint tomograms
    Mie Wiese
    Department of Oral Radiology, School of Dentistry, Faculty of Health Sciences, University of Aarhus, Denmark
    J Orofac Pain 22:239-51. 2008
    ..To identify associations between clinical symptoms of temporomandibular joint disorders and radiographic findings...
  81. doi request reprint Spatial and temporal aspects of muscle hyperalgesia induced by nerve growth factor in humans
    Helle Andersen
    Laboratory for Musculoskeletal Pain and Motor Control, Center for Sensory Motor Interaction SMI, Aalborg University, Fredrik Bajers Vej 7 D, 9220 Aalborg E, Denmark
    Exp Brain Res 191:371-82. 2008
    ..In this material there was no gender effect of NGF-induced muscle hyperalgesia. The expansion of muscle hyperalgesia to distant areas indicates that central mechanisms are involved...
  82. ncbi request reprint Human masseter inhibitory reflexes evoked by repetitive electrical stimulation
    P O Hansen
    Danish Pain Research Center and Department of Neurology, Aarhus University Hospital, Aarhus, Denmark
    Clin Neurophysiol 113:236-42. 2002
    ....
  83. ncbi request reprint Differential recruitment of endogenous pain inhibitory systems in neuropathic pain patients
    Nanna Witting
    Department of Neurology and Danish Pain Research Center, Aarhus University Hospital, DK 8000 Aarhus C, Denmark
    Pain 103:75-81. 2003
    ..The differential effect of painful HTS on ongoing pain and area of brush-evoked allodynia suggest that separate mechanisms are involved...
  84. ncbi request reprint Effect of acupuncture-like electrical stimulation on chronic tension-type headache: a randomized, double-blinded, placebo-controlled trial
    Kelun Wang
    Center for Sensory Motor Interaction, Orofacial Pain Laboratory, Aalborg University, Aalborg, Denmark
    Clin J Pain 23:316-22. 2007
    ..The aim of this study was to examine the effect of acupuncture-like electrical stimulation on chronic tension-type headache (TTH) in a randomized, double-blinded, placebo-controlled study...
  85. ncbi request reprint Central sensitization phenomena after third molar surgery: a quantitative sensory testing study
    Gitte I Juhl
    Department of Neurology and Danish Pain Research Center, Aarhus University Hospital, DK 8000 Aarhus C, Denmark
    Eur J Pain 12:116-27. 2008
    ..Surgical removal of third molars may carry a risk of developing persistent orofacial pain, and central sensitization appears to play an important role in the transition from acute to chronic pain...
  86. ncbi request reprint Long-lasting mechanical sensitization following third molar surgery
    Gitte Irene Juhl
    Department of Neurology, Danish Pain Research Center, Aarhus University Hospital, Aarhus, Denmark
    J Orofac Pain 20:59-73. 2006
    ..To investigate the degree and duration of neuronal hyperexcitability due to local inflammatory trauma after surgical removal of an impacted mandibular third molar...
  87. doi request reprint Osseous changes and condyle position in TMJ tomograms: impact of RDC/TMD clinical diagnoses on agreement between expected and actual findings
    Mie Wiese
    Department of Oral Radiology, School of Dentistry, Faculty of Health Sciences, University of Aarhus, Denmark
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 106:e52-63. 2008
    ..The objective of this study was to evaluate the impact of clinical TMJ diagnosis, gender, and age on the agreement between expected and actual radiographic findings...
  88. doi request reprint Effect of hypnosis on oral function and psychological factors in temporomandibular disorders patients
    R Abrahamsen
    Department of Clinical Oral Physiology, School of Dentistry, Aarhus University, Aarhus, Denmark
    J Oral Rehabil 36:556-70. 2009
    ..004), in number of awakenings due to pain (P < 0.006), and in somatization, obsessive compulsive symptoms and anxiety (P < 0.004). Hypnosis thus appears to effectively reduce some aspects of complex TMD pain...
  89. doi request reprint Intra-cortical excitability in healthy human subjects after tongue training
    L Baad-Hansen
    Department of Clinical Oral Physiology, School of Dentistry, Aarhus University, Aarhus C, Denmark
    J Oral Rehabil 36:427-34. 2009
    ..However, there was an association between task performance and changes in corticomotor excitability. Further studies are required to determine the clinical utility of muscle specific training for oral rehabilitation purposes...
  90. doi request reprint Effect of systemic monosodium glutamate (MSG) on headache and pericranial muscle sensitivity
    L Baad-Hansen
    Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus, Aarhus, Denmark
    Cephalalgia 30:68-76. 2010
    ..Systolic BP was elevated in the high MSG session compared with low MSG and placebo. These findings add new information to the concept of MSG headache and craniofacial pain sensitivity...
  91. ncbi request reprint Evaluation of effect of 3D video glasses on perceived pain and unpleasantness induced by restorative dental treatment
    B Bentsen
    Department of Oral Radiology, Royal Dental College, University of Aarhus, Denmark
    Eur J Pain 5:373-8. 2001
    ..These findings suggest that perceived intensity of dental pain is resistant to a simple distraction technique...
  92. ncbi request reprint Changes in jaw muscle EMG activity and pain after third molar surgery
    M Ernberg
    Department of Clinical Oral Physiology, Aarhus University, Aarhus, Denmark
    J Oral Rehabil 34:15-26. 2007
    ..However, these changes are not influenced by pain intensity. The results have implications for the understanding of the phenomenon of trismus...
  93. ncbi request reprint Patterns of experimentally induced pain in pericranial muscles
    P T Schmidt-Hansen
    Danish Pain Research Center and Department of Neurology, Aarhus University Hospital, Aarhus, Denmark
    Cephalalgia 26:568-77. 2006
    ..005). In conclusion, there appear to be characteristic pain patterns and pain sensitivity in different craniofacial muscles in healthy volunteers, which may be of importance for further research on different craniofacial pain conditions...
  94. ncbi request reprint Interstitial glutamate concentration is elevated in the masseter muscle of myofascial temporomandibular disorder patients
    Eduardo E Castrillon
    Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus, Denmark
    J Orofac Pain 24:350-60. 2010
    ..To determine if myofascial temporomandibular disorder (TMD) pain patients have elevated interstitial concentrations of glutamate in the masseter muscle...
  95. ncbi request reprint Blink reflexes in patients with atypical odontalgia and matched healthy controls
    Lene Baad-Hansen
    Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus, Vennelyst Boulevard 9, 8000, Aarhus C, Denmark
    Exp Brain Res 172:498-506. 2006
    ..Additional clinical research with AO patients will be needed to determine to what extent neuropathic pain mechanisms are involved in this pain condition...
  96. ncbi request reprint Comparison of clinical findings and psychosocial factors in patients with atypical odontalgia and temporomandibular disorders
    Lene Baad-Hansen
    Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus, Aarhus, Denmark
    J Orofac Pain 22:7-14. 2008
    ..To systematically compare clinical findings and psychosocial factors between patients suffering from atypical odontalgia (AO) and an age- and gender-matched group of patients with temporomandibular disorders (TMD)...
  97. ncbi request reprint Blink reflexes in patients with atypical odontalgia
    Lene Baad-Hansen
    Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus, Aarhus, Denmark
    J Orofac Pain 19:239-47. 2005
    ..To use the human blink reflex (BR) to explore possible neuropathic pain mechanisms in patients with atypical odontalgia (AO)...
  98. ncbi request reprint Effect of peripheral NMDA receptor blockade with ketamine on chronic myofascial pain in temporomandibular disorder patients: a randomized, double-blinded, placebo-controlled trial
    Eduardo E Castrillon
    Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus, Aarhus, Denmark
    J Orofac Pain 22:122-30. 2008
    ..To investigate the effects of local intramuscular injection of the N-methyl-D-aspartate (NMDA) receptor antagonist ketamine on chronic myofascial pain and mandibular function in temporomandibular disorder patients...
  99. doi request reprint Effect of experimental pain on EMG-activity in human jaw-closing muscles in different jaw positions
    Lene Baad-Hansen
    Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus, DK 8000 Aarhus C, Denmark
    Arch Oral Biol 54:32-9. 2009
    ..05). Conclusions: It is concluded that experimental pain affects EMG-activity differentially in jaw-closing muscles in different opening positions of the jaw...
  100. ncbi request reprint Lack of sex differences in modulation of experimental intraoral pain by diffuse noxious inhibitory controls (DNIC)
    Lene Baad-Hansen
    Department Clinical Oral Physiology, School of Dentistry, University of Aarhus, Vennelyst Boulevard 9, DK 8000 Aarhus C, Denmark
    Pain 116:359-65. 2005
    ..Female sex and the use of OC may not consistently be associated with higher sensitivity to pain...
  101. pmc Glutamate-evoked jaw muscle pain as a model of persistent myofascial TMD pain?
    Eduardo E Castrillon
    Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus, Aarhus C, Denmark
    Arch Oral Biol 53:666-76. 2008
    ..Compare pain-related measures and psychosocial variables between glutamate-evoked jaw muscle pain in healthy subjects (HS) and patients with persistent myofascial temporomandibular disorder (TMD) pain...