Mette Soerensen

Summary

Affiliation: University of Southern Denmark
Country: Denmark

Publications

  1. ncbi request reprint Genetic variation and human longevity
    Mette Soerensen
    Danish Aging Research Center, Epidemiology, Institute of Public Health, University of Southern Denmark, J B Winsløws Vej 9B, 5000 Odense C, Denmark
    Dan Med J 59:B4454. 2012
  2. pmc Evidence from case-control and longitudinal studies supports associations of genetic variation in APOE, CETP, and IL6 with human longevity
    Mette Soerensen
    The Danish Aging Research Center, Epidemiology, Institute of Public Health, University of Southern Denmark
    Age (Dordr) 35:487-500. 2013
  3. pmc Genetic variation in TERT and TERC and human leukocyte telomere length and longevity: a cross-sectional and longitudinal analysis
    Mette Soerensen
    The Danish Aging Research Center, Epidemiology, Institute of Public Health, University of Southern Denmark, Odense C, Denmark
    Aging Cell 11:223-7. 2012
  4. pmc The Mn-superoxide dismutase single nucleotide polymorphism rs4880 and the glutathione peroxidase 1 single nucleotide polymorphism rs1050450 are associated with aging and longevity in the oldest old
    Mette Soerensen
    Danish Aging Research Center, Epidemiology, Institute of Public Health, University of Southern Denmark, J B Winsloews Vej 9B, 5000 Odense C, Denmark
    Mech Ageing Dev 130:308-14. 2009
  5. pmc Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data
    Mette Soerensen
    The Danish Aging Research Center, Epidemiology, Institute of Public Health, University of Southern Denmark, Odense C, Denmark
    Aging Cell 9:1010-7. 2010
  6. pmc Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studies
    Mette Soerensen
    The Danish Aging Research Center, Epidemiology, Institute of Public Health, University of Southern Denmark, JB Winsloews Vej 9B, 5000 Odense C, Denmark
    Exp Gerontol 47:379-87. 2012
  7. pmc AKT1 fails to replicate as a longevity-associated gene in Danish and German nonagenarians and centenarians
    Marianne Nygaard
    Epidemiology, Institute of Public Health, University of Southern Denmark, Odense C, Denmark
    Eur J Hum Genet 21:574-7. 2013
  8. pmc A novel permutation test for case-only analysis identifies epistatic effects on human longevity in the FOXO gene family
    Qihua Tan
    Epidemiology, Institute of Public Health, University of Southern Denmark, Odense C, Denmark
    Aging Cell 12:690-4. 2013
  9. pmc UCP3 polymorphisms, hand grip performance and survival at old age: association analysis in two Danish middle aged and elderly cohorts
    Serena Dato
    Department of Cell Biology, University of Calabria, Ponte Pietro Bucci cubo 4C, 87036 Rende CS, Italy
    Mech Ageing Dev 133:530-7. 2012

Detail Information

Publications9

  1. ncbi request reprint Genetic variation and human longevity
    Mette Soerensen
    Danish Aging Research Center, Epidemiology, Institute of Public Health, University of Southern Denmark, J B Winsløws Vej 9B, 5000 Odense C, Denmark
    Dan Med J 59:B4454. 2012
    ..Data on one of these genes (IL6) have been included in a manuscript...
  2. pmc Evidence from case-control and longitudinal studies supports associations of genetic variation in APOE, CETP, and IL6 with human longevity
    Mette Soerensen
    The Danish Aging Research Center, Epidemiology, Institute of Public Health, University of Southern Denmark
    Age (Dordr) 35:487-500. 2013
    ..In conclusion, we here support and expand the evidence suggesting that genetic variation in APOE, CETP, and IL6, and possible HSPA14, is associated with human longevity...
  3. pmc Genetic variation in TERT and TERC and human leukocyte telomere length and longevity: a cross-sectional and longitudinal analysis
    Mette Soerensen
    The Danish Aging Research Center, Epidemiology, Institute of Public Health, University of Southern Denmark, Odense C, Denmark
    Aging Cell 11:223-7. 2012
    ..31, P = 0.006]. No associations with longevity were observed for the TERT SNPs or haplotypes. Our study, thus, indicates that TERC is associated with both LTL and longevity in humans...
  4. pmc The Mn-superoxide dismutase single nucleotide polymorphism rs4880 and the glutathione peroxidase 1 single nucleotide polymorphism rs1050450 are associated with aging and longevity in the oldest old
    Mette Soerensen
    Danish Aging Research Center, Epidemiology, Institute of Public Health, University of Southern Denmark, J B Winsloews Vej 9B, 5000 Odense C, Denmark
    Mech Ageing Dev 130:308-14. 2009
    ..Our results thus indicate that genetic variation in MnSOD and GPX1 may be associated with aging and longevity...
  5. pmc Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data
    Mette Soerensen
    The Danish Aging Research Center, Epidemiology, Institute of Public Health, University of Southern Denmark, Odense C, Denmark
    Aging Cell 9:1010-7. 2010
    ..Hence, our results support and extent the proposed role of FOXO3A as a candidate longevity gene for survival from younger ages to old age, yet not during old age...
  6. pmc Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studies
    Mette Soerensen
    The Danish Aging Research Center, Epidemiology, Institute of Public Health, University of Southern Denmark, JB Winsloews Vej 9B, 5000 Odense C, Denmark
    Exp Gerontol 47:379-87. 2012
    ....
  7. pmc AKT1 fails to replicate as a longevity-associated gene in Danish and German nonagenarians and centenarians
    Marianne Nygaard
    Epidemiology, Institute of Public Health, University of Southern Denmark, Odense C, Denmark
    Eur J Hum Genet 21:574-7. 2013
    ..Overall, our results do not support AKT1 as a universal longevity-associated gene...
  8. pmc A novel permutation test for case-only analysis identifies epistatic effects on human longevity in the FOXO gene family
    Qihua Tan
    Epidemiology, Institute of Public Health, University of Southern Denmark, Odense C, Denmark
    Aging Cell 12:690-4. 2013
    ..23, 95% CI: 2.93-3.53) which is consistent in both males and females. Our results were compared with published studies, and importance of our novel method and findings was discussed...
  9. pmc UCP3 polymorphisms, hand grip performance and survival at old age: association analysis in two Danish middle aged and elderly cohorts
    Serena Dato
    Department of Cell Biology, University of Calabria, Ponte Pietro Bucci cubo 4C, 87036 Rende CS, Italy
    Mech Ageing Dev 133:530-7. 2012
    ..On the whole, our work supports the role of UCP3 gene in functional status and survival at old age...