Morten Schou

Summary

Affiliation: University of Copenhagen
Country: Denmark

Publications

  1. pmc Renal dysfunction, restrictive left ventricular filling pattern and mortality risk in patients admitted with heart failure: a 7-year follow-up study
    Morten Schou
    Department of Cardiology, The Heart Centre and University of Copenhagen, Rigshospitalet, DK 2100 Copenhagen, Denmark
    BMC Nephrol 14:267. 2013
  2. doi request reprint Adding serial N-terminal pro brain natriuretic peptide measurements to optimal clinical management in outpatients with systolic heart failure: a multicentre randomized clinical trial (NorthStar monitoring study)
    Morten Schou
    Rigshospitalet, DK 2100 Copenhagen E, Denmark
    Eur J Heart Fail 15:818-27. 2013
  3. doi request reprint Extended heart failure clinic follow-up in low-risk patients: a randomized clinical trial (NorthStar)
    Morten Schou
    Department of Cardiology and Endocrinology, Frederiksberg University Hospital, DK 2000 Frderiksberg, Denmark
    Eur Heart J 34:432-42. 2013
  4. ncbi request reprint Kidneys extract BNP and NT-proBNP in healthy young men
    Morten Schou
    Dept of Endocrinology and Cardiology, Frederiksberg Univ Hospital, Ndr Fasanvej 57 59, DK 2000 Frederiksberg, Denmark
    J Appl Physiol (1985) 99:1676-80. 2005
  5. doi request reprint Plasma sodium and mortality risk in patients with myocardial infarction and a low LVEF
    Morten Schou
    The Heart Centre, Department of Cardiology, Righospitalet, Copenhagen, Denmark
    Eur J Clin Invest 41:1237-44. 2011
  6. doi request reprint Effect of estimated glomerular filtration rate on plasma concentrations of B-type natriuretic peptides measured with multiple immunoassays in elderly individuals
    M Schou
    Department of Endocrinology and Cardiology, Hillerod University Hospital, Hillerod, Denmark
    Heart 95:1514-9. 2009
  7. ncbi request reprint Design and methodology of the NorthStar Study: NT-proBNP stratified follow-up in outpatient heart failure clinics -- a randomized Danish multicenter study
    Morten Schou
    The Danish Heart Failure Clinics Network, C O Frederiksberg University Hospital, Frederiksberg, Denmark
    Am Heart J 156:649-55. 2008
  8. doi request reprint Wall motion index, estimated glomerular filtration rate and mortality risk in patients with heart failure or myocardial infarction: a pooled analysis of 18,010 patients
    Morten Schou
    Department of Cardiology, The Heart Centre, Rigshospitalet University Hospital, DK 2100 Copenhagen O, Denmark
    Eur J Heart Fail 10:682-8. 2008
  9. ncbi request reprint Prognostic usefulness of anemia and N-terminal pro-brain natriuretic peptide in outpatients with systolic heart failure
    Morten Schou
    Department of Cardiology and Endocrinology, Frederiksberg University Hospital, Frederiksberg, Denmark
    Am J Cardiol 100:1571-6. 2007
  10. ncbi request reprint Effects of body mass index and age on N-terminal pro brain natriuretic peptide are associated with glomerular filtration rate in chronic heart failure patients
    Morten Schou
    Department of Cardiology and Endocrinology, Clinic E, Frederiksberg University Hospital, Frederiksberg, Denmark
    Clin Chem 53:1928-35. 2007

Detail Information

Publications32

  1. pmc Renal dysfunction, restrictive left ventricular filling pattern and mortality risk in patients admitted with heart failure: a 7-year follow-up study
    Morten Schou
    Department of Cardiology, The Heart Centre and University of Copenhagen, Rigshospitalet, DK 2100 Copenhagen, Denmark
    BMC Nephrol 14:267. 2013
    ..This study was designed to evaluate whether severe diastolic dysfunction contribute to the increased mortality risk observed in HF patients with renal dysfunction...
  2. doi request reprint Adding serial N-terminal pro brain natriuretic peptide measurements to optimal clinical management in outpatients with systolic heart failure: a multicentre randomized clinical trial (NorthStar monitoring study)
    Morten Schou
    Rigshospitalet, DK 2100 Copenhagen E, Denmark
    Eur J Heart Fail 15:818-27. 2013
    ..This study was designed to evaluate a new NT-proBNP monitoring concept in outpatients with systolic heart failure (HF)...
  3. doi request reprint Extended heart failure clinic follow-up in low-risk patients: a randomized clinical trial (NorthStar)
    Morten Schou
    Department of Cardiology and Endocrinology, Frederiksberg University Hospital, DK 2000 Frderiksberg, Denmark
    Eur Heart J 34:432-42. 2013
    ..Nor is it known whether all or only high-risk patients, e.g. identified by NT-proBNP, might benefit from an extended HFC follow-up...
  4. ncbi request reprint Kidneys extract BNP and NT-proBNP in healthy young men
    Morten Schou
    Dept of Endocrinology and Cardiology, Frederiksberg Univ Hospital, Ndr Fasanvej 57 59, DK 2000 Frederiksberg, Denmark
    J Appl Physiol (1985) 99:1676-80. 2005
    ..15-0.20. There is no cerebral extraction, and short-term moderate exercise does not affect these values. Our findings suggest that the kidneys extract BNP and NT-proBNP to a similar extent in healthy young men...
  5. doi request reprint Plasma sodium and mortality risk in patients with myocardial infarction and a low LVEF
    Morten Schou
    The Heart Centre, Department of Cardiology, Righospitalet, Copenhagen, Denmark
    Eur J Clin Invest 41:1237-44. 2011
    ..This study was, therefore, designed to evaluate whether plasma sodium and hyponatremia (< 135 mM) are associated with mortality risk in patients with MI...
  6. doi request reprint Effect of estimated glomerular filtration rate on plasma concentrations of B-type natriuretic peptides measured with multiple immunoassays in elderly individuals
    M Schou
    Department of Endocrinology and Cardiology, Hillerod University Hospital, Hillerod, Denmark
    Heart 95:1514-9. 2009
    ....
  7. ncbi request reprint Design and methodology of the NorthStar Study: NT-proBNP stratified follow-up in outpatient heart failure clinics -- a randomized Danish multicenter study
    Morten Schou
    The Danish Heart Failure Clinics Network, C O Frederiksberg University Hospital, Frederiksberg, Denmark
    Am Heart J 156:649-55. 2008
    ..Furthermore, data on the use of natriuretic peptides for monitoring of stable patients with CHF are sparse...
  8. doi request reprint Wall motion index, estimated glomerular filtration rate and mortality risk in patients with heart failure or myocardial infarction: a pooled analysis of 18,010 patients
    Morten Schou
    Department of Cardiology, The Heart Centre, Rigshospitalet University Hospital, DK 2100 Copenhagen O, Denmark
    Eur J Heart Fail 10:682-8. 2008
    ....
  9. ncbi request reprint Prognostic usefulness of anemia and N-terminal pro-brain natriuretic peptide in outpatients with systolic heart failure
    Morten Schou
    Department of Cardiology and Endocrinology, Frederiksberg University Hospital, Frederiksberg, Denmark
    Am J Cardiol 100:1571-6. 2007
    ..Patients with anemia and high levels of NT-pro-BNP have a markedly increased mortality risk...
  10. ncbi request reprint Effects of body mass index and age on N-terminal pro brain natriuretic peptide are associated with glomerular filtration rate in chronic heart failure patients
    Morten Schou
    Department of Cardiology and Endocrinology, Clinic E, Frederiksberg University Hospital, Frederiksberg, Denmark
    Clin Chem 53:1928-35. 2007
    ..We hypothesized that the effects of BMI and age on plasma concentrations of NT-proBNP are associated with GFR...
  11. doi request reprint Prediction of outcome by highly sensitive troponin T in outpatients with chronic systolic left ventricular heart failure
    Michael Egstrup
    Department of Cardiology and Endocrinology, Frederiksberg University Hospital, Frederiksberg, Denmark
    Am J Cardiol 110:552-7. 2012
    ..Increased hs-cTnT indicated a particularly deleterious prognosis in patients without CAD...
  12. ncbi request reprint Prevalence and prognostic significance of atrial fibrillation in outpatients with heart failure due to left ventricular systolic dysfunction
    Pernille Corell
    Department of Cardiology and Endocrinology E, Frederiksberg University Hospital, Frederiksberg, Denmark
    Eur J Heart Fail 9:258-65. 2007
    ..The aim of our study was to assess the prevalence and incidence of AF in patients with HF and to determine the prognostic impact of baseline AF and the development of new onset AF...
  13. doi request reprint Incidence and predictors of hospitalization or death in patients managed in multidisciplinary heart failure clinics
    Finn Gustafsson
    Department of Cardiology B, The Heart Centre, Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Eur J Heart Fail 11:413-9. 2009
    ..A second aim was to identify risk factors for death or hospital admission...
  14. ncbi request reprint The relationship between N-terminal pro-brain natriuretic peptide and risk for hospitalization and mortality is curvilinear in patients with chronic heart failure
    Morten Schou
    Department of Cardiology and Endocrinology, Clinic E, Frederiksberg University Hospital, Frederiksberg, Denmark
    Am Heart J 154:123-9. 2007
    ..We therefore evaluated NT-proBNP as a risk marker for mortality and hospitalization and developed a simple algorithm for risk stratification based on NT-proBNP as a continuous variable...
  15. doi request reprint Plasma copeptin levels and prediction of outcome in heart failure outpatients: relation to hyponatremia and loop diuretic doses
    Louise Balling
    Department of Cardiology, Rigshospitalet, Copenhagen, Denmark
    J Card Fail 18:351-8. 2012
    ....
  16. ncbi request reprint Treatment with beta-blockers in nurse-led heart failure clinics: titration efficacy and predictors of failure
    Finn Gustafsson
    Department of Cardiology, Rigshospitalet, Copenhagen, Denmark
    Eur J Heart Fail 9:910-6. 2007
    ..However, little information is available to describe if such programs are successful in initiating and up-titrating BBs in daily clinical practice...
  17. doi request reprint Haemodynamic response during low-dose dobutamine infusion in patients with chronic systolic heart failure: comparison of echocardiographic and invasive measurements
    Michael Egstrup
    Department of Cardiology and Endocrinology, Frederiksberg University Hospital, Nordre Fasanvej 59, Frederiksberg, Denmark
    Eur Heart J Cardiovasc Imaging 14:659-67. 2013
    ....
  18. doi request reprint Prevalence and prognostic significance of hyponatraemia in outpatients with chronic heart failure
    Louise Balling
    Department of Cardiology, Rigshospitalet, Copenhagen, Denmark
    Eur J Heart Fail 13:968-73. 2011
    ..The aim of the study was to determine the prevalence and prognostic significance of hyponatraemia in a large cohort of HF outpatients followed in clinics participating in the Danish Heart Failure Clinics Network...
  19. doi request reprint Patient adherence to evidence-based pharmacotherapy in systolic heart failure and the transition of follow-up from specialized heart failure outpatient clinics to primary care
    Anne Gjesing
    Department of Cardiology, Gentofte University Hospital, Post 635, Niels Andersens Vej 65, 2900 Hellerup, Denmark
    Eur J Heart Fail 15:671-8. 2013
    ..The objective of this study was to examine long-term adherence to and dosages of evidence-based pharmacotherapy during and after participation in specialized HFCs...
  20. doi request reprint Prognostic threshold levels of NT-proBNP testing in primary care
    Jens Rosenberg
    Department of Cardiology, Frederiksberg University Hospital, Nordre Fasanvej, Frederiksberg, Denmark
    Eur Heart J 30:66-73. 2009
    ..We investigated whether a prognostic threshold level of the cardiac peptide, NT-proBNP, could be identified...
  21. doi request reprint Incidence and predictors of end-stage renal disease in outpatients with systolic heart failure
    Helle Bosselmann
    Departments of Cardio, Nephro, and Endocrinology, North Zealand Hospital, University of Copenhagen, Hillerod, Denmark
    Circ Heart Fail 6:1124-31. 2013
    ..Renal dysfunction is an important prognostic factor in heart failure (HF), but whether this dysfunction progresses to end-stage renal disease (ESRD) is unknown. Therefore, we examined incidence and predictors of ESRD in outpatients with HF...
  22. pmc Renal function at the time of a myocardial infarction maintains prognostic value for more than 10 years
    Thomas Kümler
    Dept of Cardiology, Rigshospitalet, Copenhagen University Hospital, Denmark
    BMC Cardiovasc Disord 11:37. 2011
    ..We examined the importance of renal function by estimated GFR (eGFR) and se-creatinine as an independent long-term prognostic factor...
  23. ncbi request reprint Long-term clinical variation of NT-proBNP in stable chronic heart failure patients
    Morten Schou
    Department of Cardiology and Endocrinology, Clinic E, Frederiksberg University Hospital, Ndr Fasanvej 57 59, DK 2000 Frederiksberg, Denmark
    Eur Heart J 28:177-82. 2007
    ..The proposed use of NT-proBNP for monitoring of CHF patients will require accurate information about long-term CV of the peptide...
  24. ncbi request reprint Unexplained week-to-week variation in BNP and NT-proBNP is low in chronic heart failure patients during steady state
    Morten Schou
    Department of Cardiology and Endocrinology, Clinic E, Frederiksberg University Hospital, Ndr Fasanvej 57 59, DK 2000 Frederiksberg, Denmark
    Eur J Heart Fail 9:68-74. 2007
    ..The usefulness of brain-natriuretic-peptide (BNP) and N-terminal-pro-brain-natriuretic-peptide (NT-proBNP) for monitoring of chronic heart failure (CHF) patients has been questioned because of high levels of unexplained variation...
  25. doi request reprint α-Defensins and outcome in patients with chronic heart failure
    Heidi M Christensen
    Department of Cardiology, Herlev University Hospital, Herlev Ringvej 75, Herlev, Denmark
    Eur J Heart Fail 14:387-94. 2012
    ....
  26. ncbi request reprint Effect of atrial fibrillation on plasma NT-proBNP in chronic heart failure
    Pernille Corell
    Department of Cardiology and Endocrinology E, Frederiksberg University Hospital, Ndr Fasanvej 57, 2000 Frederiksberg, Denmark
    Int J Cardiol 117:395-402. 2007
    ..The aim of our study was to examine the levels of N-terminal pro brain natriuretic peptide (NT-proBNP) in patients with HF and AF versus HF and sinus rhythm (SR) and if NT-proBNP has prognostic influence in patients with AF...
  27. doi request reprint Oral glucose tolerance testing in an outpatient heart failure clinic reveals a high proportion of undiagnosed diabetic patients with an adverse prognosis
    Michael Egstrup
    Department of Cardiology and Endocrinology, Frederiksberg University Hospital, Nordre Fasanvej 59, 2000 Frederiksberg, Denmark
    Eur J Heart Fail 13:319-26. 2011
    ..We evaluated the applicability and prognostic importance of oral glucose tolerance testing (OGTT) among outpatients with systolic heart failure (SHF)...
  28. doi request reprint Efficacy and safety of Angiotensin-converting enzyme inhibitors in patients with left ventricular systolic dysfunction and hyponatremia
    Louise Balling
    Heart Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark Electronic address
    J Card Fail 19:725-30. 2013
    ....
  29. doi request reprint High mortality among heart failure patients treated with antidepressants
    Karsten T Veien
    Department of Cardiology, Odense University Hospital, Sdr Boulevard 29, DK 5000 Odense, Denmark
    Int J Cardiol 146:64-7. 2011
    ..This study was designed to assess whether pharmacologically treated depression was associated with increased mortality risk in systolic heart failure (SHF) patients...
  30. doi request reprint Identifying the functional part of heparin-binding protein (HBP) as a monocyte stimulator and the novel role of monocytes as HBP producers
    Morten Schou
    Bartholin Instituttet XPU, Biocenter Copenhagen, Rigshospitalet, Blegdamsvej 9, Copenhagen Ø, Denmark
    Innate Immun 17:60-9. 2011
    ..Furthermore, a small amount of HBP can be demonstrated when monocytes are incubated in medium alone. Our efforts to identify a suggested HBP receptor on monocytes has failed so far...
  31. ncbi request reprint Angiotensin II attenuates the natriuresis of water immersion in humans
    Morten Schou
    Department of Aviation Medicine, The Heart Centre, The National University Hospital Rigshospitalet Dept 7522, 9 Blegdamsvej, DK 2100 Copenhagen, Denmark
    Am J Physiol Regul Integr Comp Physiol 283:R187-96. 2002
    ..Furthermore, infusion of ANG II during WI prevents an otherwise induced increase in C(Li) and facilitates the fractional distal reabsorption of sodium, probably via an effect on aldosterone release...
  32. ncbi request reprint Comparison of acute cardiovascular responses to water immersion and head-down tilt in humans
    Makoto Shiraishi
    Neurology Division, St Marianna University School of Medicine, Kawasaki, Kanagawa 216 8511, Japan
    J Appl Physiol (1985) 92:264-8. 2002
    ..In conclusion, the hypothesis was not confirmed because the cardiac atria were similarly distended by acute HDT and WI and the release of vasoconstrictor hormones were suppressed to the same extent...