H Schmalbruch

Summary

Affiliation: University of Copenhagen
Country: Denmark

Publications

  1. ncbi request reprint Dynamics of nuclei of muscle fibers and connective tissue cells in normal and denervated rat muscles
    H Schmalbruch
    Department of Medical Physiology, Division of Neurophysiology, University of Copenhagen, The Panum Institute, Blegdamsvej 3 C, DK 2200 Copenhagen N, Denmark
    Muscle Nerve 23:617-26. 2000
  2. ncbi request reprint Spinal muscular atrophy: present state
    H Schmalbruch
    Department of Medical Physiology, University of Copenhagen, Denmark
    Brain Pathol 11:231-47. 2001
  3. ncbi request reprint Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy
    M Sendtner
    Department of Neurochemistry, Max Planck Institute for Psychiatry, Martinsried, Germany
    Nature 358:502-4. 1992
  4. ncbi request reprint Polymer encapsulated cell lines genetically engineered to release ciliary neurotrophic factor can slow down progressive motor neuronopathy in the mouse
    Y Sagot
    Department of Pharmacology, Centre Medical Universitaire, Geneva, Switzerland
    Eur J Neurosci 7:1313-22. 1995
  5. ncbi request reprint The mouse mutation progressive motor neuronopathy (pmn) maps to chromosome 13
    A L Brunialti
    Unite de Genetique des Mammiferes, Institut Pasteur, Paris, France
    Genomics 29:131-5. 1995
  6. ncbi request reprint Gene therapy of murine motor neuron disease using adenoviral vectors for neurotrophic factors
    G Haase
    INSERM Unit 129, Institut Cochin de Genetique Moleculaire, Paris, France
    Nat Med 3:429-36. 1997
  7. ncbi request reprint Electromyographical and motor performance studies in the pmn mouse model of neurodegenerative disease
    P F Kennel
    Departement d Immunologie, Immunopharmacologie et Pathologie, Centre de Recherches Pharmaceutiques, Universite Louis Pasteur, Illkirch, France
    Neurobiol Dis 3:137-47. 1996
  8. ncbi request reprint Adenovirus-mediated transfer of the neurotrophin-3 gene into skeletal muscle of pmn mice: therapeutic effects and mechanisms of action
    G Haase
    INSERM U 129, ICGM, 24, Paris, France
    J Neurol Sci 160:S97-105. 1998
  9. ncbi request reprint Protective effects of cardiotrophin-1 adenoviral gene transfer on neuromuscular degeneration in transgenic ALS mice
    T Bordet
    Département de génétique, Institut Cochin de Genetique Moleculaire, 24, rue du Fg Saint Jacques, 75014 Paris, France
    Hum Mol Genet 10:1925-33. 2001

Collaborators

  • G Haase
  • M Azzouz
  • P Kennel
  • T Bordet
  • A Kahn
  • S Rouhani
  • J C Lesbordes
  • L Castelnau-Ptakhine
  • A L Brunialti
  • Y Sagot
  • J L Guenet
  • E Baetge
  • C Poirier
  • S A Tan
  • P Aebischer
  • A C Kato
  • M Sendtner
  • P Carroll
  • K A Stöckli
  • H Thoenen
  • G W Kreutzberg

Detail Information

Publications9

  1. ncbi request reprint Dynamics of nuclei of muscle fibers and connective tissue cells in normal and denervated rat muscles
    H Schmalbruch
    Department of Medical Physiology, Division of Neurophysiology, University of Copenhagen, The Panum Institute, Blegdamsvej 3 C, DK 2200 Copenhagen N, Denmark
    Muscle Nerve 23:617-26. 2000
    ..The cause may possibly be that the phase of postdenervation fibrillation is shorter than in other muscles...
  2. ncbi request reprint Spinal muscular atrophy: present state
    H Schmalbruch
    Department of Medical Physiology, University of Copenhagen, Denmark
    Brain Pathol 11:231-47. 2001
    ..These include SMN gene transfer, molecules capable to up-regulate SMN expression and trophic or antiapoptotic factors...
  3. ncbi request reprint Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy
    M Sendtner
    Department of Neurochemistry, Max Planck Institute for Psychiatry, Martinsried, Germany
    Nature 358:502-4. 1992
    ..The protective and restorative effects of CNTF in this mouse mutant give new perspectives for the treatment of human degenerative motor neuron diseases with CNTF...
  4. ncbi request reprint Polymer encapsulated cell lines genetically engineered to release ciliary neurotrophic factor can slow down progressive motor neuronopathy in the mouse
    Y Sagot
    Department of Pharmacology, Centre Medical Universitaire, Geneva, Switzerland
    Eur J Neurosci 7:1313-22. 1995
    ..These results suggest that polymer-encapsulated cells releasing neurotrophic factors may provide a potential delivery system for treating neurodegenerative diseases such as ALS...
  5. ncbi request reprint The mouse mutation progressive motor neuronopathy (pmn) maps to chromosome 13
    A L Brunialti
    Unite de Genetique des Mammiferes, Institut Pasteur, Paris, France
    Genomics 29:131-5. 1995
    ..The presence of the Extra-toe (Xt) locus in proximity to pmn will help in the detection of affected progenies before the onset of the degenerative process...
  6. ncbi request reprint Gene therapy of murine motor neuron disease using adenoviral vectors for neurotrophic factors
    G Haase
    INSERM Unit 129, Institut Cochin de Genetique Moleculaire, Paris, France
    Nat Med 3:429-36. 1997
    ..Therefore, adenovirus-mediated gene transfer of neurotrophic factors offers new prospects for the treatment of motor neuron diseases...
  7. ncbi request reprint Electromyographical and motor performance studies in the pmn mouse model of neurodegenerative disease
    P F Kennel
    Departement d Immunologie, Immunopharmacologie et Pathologie, Centre de Recherches Pharmaceutiques, Universite Louis Pasteur, Illkirch, France
    Neurobiol Dis 3:137-47. 1996
    ....
  8. ncbi request reprint Adenovirus-mediated transfer of the neurotrophin-3 gene into skeletal muscle of pmn mice: therapeutic effects and mechanisms of action
    G Haase
    INSERM U 129, ICGM, 24, Paris, France
    J Neurol Sci 160:S97-105. 1998
    ....
  9. ncbi request reprint Protective effects of cardiotrophin-1 adenoviral gene transfer on neuromuscular degeneration in transgenic ALS mice
    T Bordet
    Département de génétique, Institut Cochin de Genetique Moleculaire, 24, rue du Fg Saint Jacques, 75014 Paris, France
    Hum Mol Genet 10:1925-33. 2001
    ..Thus, adenovirus-mediated gene transfer of neurotrophic factors might delay neurogenic muscular atrophy and progressive neuromuscular deficiency in ALS patients...