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Genomes and Genes | Cathrine ØrskovSummaryAffiliation: University of Copenhagen Country: Denmark Publications
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Publications
Typical Danish Caucasian type 2 diabetic patients do not commonly carry genetic variants in GIP and GLP-1 encoding regions of the proGIP and proglucagon genesCathrine Ørskov
Department of Medical Anatomy, The Panum Institute, University of Copenhagen, Blegdamsvej 3C, Copenhagen DK 2200, Denmark
Regul Pept 119:151-4. 2004..Thus, the aim of this study was to study the occurrence of genetic variants in the GIP and GLP-1 encoding regions of the proGIP and proglucagon genes in type 2 diabetic patients and matched control subjects...
GLP-2 stimulates colonic growth via KGF, released by subepithelial myofibroblasts with GLP-2 receptorsCathrine Ørskov
Department of Medical Anatomy, The Panum Institute, University of Copenhagen, Blegdamsvej 3C, Copenhagen DK 2200, Denmark
Regul Pept 124:105-12. 2005..Glucagon-like peptide-2 is thought to act as a growth factor for the gut, but the localization of the GLP-2 receptor and mechanism of action on epithelial growth is unclear...
The truncated metabolite GLP-2 (3-33) interacts with the GLP-2 receptor as a partial agonistJesper Thulesen
Department of Medical Anatomy, Section B, The Panum Institute, University of Copenhagen, Blegdamsvej 3, 2200 N, Copenhagen, Denmark
Regul Pept 103:9-15. 2002..Consistent with the observed in vivo activities, our functional studies and binding data indicate that GLP-2 (3-33) acts as a partial agonist with potential competitive antagonistic properties on the GLP-2 receptor...
Impaired intestinal proglucagon processing in mice lacking prohormone convertase 1Randi Ugleholdt
Department of Medical Physiology, The Panum Institute, University of Copenhagen, DK 2200 Copenhagen N, Denmark
Endocrinology 145:1349-55. 2004..These findings strongly suggest that PC1 is essential for intestinal proglucagon processing in vivo and, thereby, plays an important role in production of the incretin hormone GLP-1 and the intestinotrophic hormone GLP-2...
Quality of the transgene-specific CD8+ T cell response induced by adenoviral vector immunization is critically influenced by virus dose and route of vaccinationPeter Johannes Holst
Department of International Health, University of Copenhagen, Copenhagen, Denmark
J Immunol 184:4431-9. 2010..These findings indicate that the localization of the adenoviral inoculum and not the total Ag load determines the quality of the CD8(+) T cell response induced with adenoviral vaccines...
