Cathrine Ørskov

Summary

Affiliation: University of Copenhagen
Country: Denmark

Publications

  1. ncbi Typical Danish Caucasian type 2 diabetic patients do not commonly carry genetic variants in GIP and GLP-1 encoding regions of the proGIP and proglucagon genes
    Cathrine Ørskov
    Department of Medical Anatomy, The Panum Institute, University of Copenhagen, Blegdamsvej 3C, Copenhagen DK 2200, Denmark
    Regul Pept 119:151-4. 2004
  2. ncbi GLP-2 stimulates colonic growth via KGF, released by subepithelial myofibroblasts with GLP-2 receptors
    Cathrine Ørskov
    Department of Medical Anatomy, The Panum Institute, University of Copenhagen, Blegdamsvej 3C, Copenhagen DK 2200, Denmark
    Regul Pept 124:105-12. 2005
  3. ncbi The truncated metabolite GLP-2 (3-33) interacts with the GLP-2 receptor as a partial agonist
    Jesper Thulesen
    Department of Medical Anatomy, Section B, The Panum Institute, University of Copenhagen, Blegdamsvej 3, 2200 N, Copenhagen, Denmark
    Regul Pept 103:9-15. 2002
  4. ncbi Impaired intestinal proglucagon processing in mice lacking prohormone convertase 1
    Randi Ugleholdt
    Department of Medical Physiology, The Panum Institute, University of Copenhagen, DK 2200 Copenhagen N, Denmark
    Endocrinology 145:1349-55. 2004
  5. doi Quality of the transgene-specific CD8+ T cell response induced by adenoviral vector immunization is critically influenced by virus dose and route of vaccination
    Peter Johannes Holst
    Department of International Health, University of Copenhagen, Copenhagen, Denmark
    J Immunol 184:4431-9. 2010
  6. pmc Metformin stimulates FGF21 expression in primary hepatocytes
    Eva B Nygaard
    Department of Pharmacology and Pharmacotherapy, University of Copenhagen, 2100 Copenhagen, Denmark
    Exp Diabetes Res 2012:465282. 2012

Collaborators

Detail Information

Publications6

  1. ncbi Typical Danish Caucasian type 2 diabetic patients do not commonly carry genetic variants in GIP and GLP-1 encoding regions of the proGIP and proglucagon genes
    Cathrine Ørskov
    Department of Medical Anatomy, The Panum Institute, University of Copenhagen, Blegdamsvej 3C, Copenhagen DK 2200, Denmark
    Regul Pept 119:151-4. 2004
    ..Thus, the aim of this study was to study the occurrence of genetic variants in the GIP and GLP-1 encoding regions of the proGIP and proglucagon genes in type 2 diabetic patients and matched control subjects...
  2. ncbi GLP-2 stimulates colonic growth via KGF, released by subepithelial myofibroblasts with GLP-2 receptors
    Cathrine Ørskov
    Department of Medical Anatomy, The Panum Institute, University of Copenhagen, Blegdamsvej 3C, Copenhagen DK 2200, Denmark
    Regul Pept 124:105-12. 2005
    ..Glucagon-like peptide-2 is thought to act as a growth factor for the gut, but the localization of the GLP-2 receptor and mechanism of action on epithelial growth is unclear...
  3. ncbi The truncated metabolite GLP-2 (3-33) interacts with the GLP-2 receptor as a partial agonist
    Jesper Thulesen
    Department of Medical Anatomy, Section B, The Panum Institute, University of Copenhagen, Blegdamsvej 3, 2200 N, Copenhagen, Denmark
    Regul Pept 103:9-15. 2002
    ..Consistent with the observed in vivo activities, our functional studies and binding data indicate that GLP-2 (3-33) acts as a partial agonist with potential competitive antagonistic properties on the GLP-2 receptor...
  4. ncbi Impaired intestinal proglucagon processing in mice lacking prohormone convertase 1
    Randi Ugleholdt
    Department of Medical Physiology, The Panum Institute, University of Copenhagen, DK 2200 Copenhagen N, Denmark
    Endocrinology 145:1349-55. 2004
    ..These findings strongly suggest that PC1 is essential for intestinal proglucagon processing in vivo and, thereby, plays an important role in production of the incretin hormone GLP-1 and the intestinotrophic hormone GLP-2...
  5. doi Quality of the transgene-specific CD8+ T cell response induced by adenoviral vector immunization is critically influenced by virus dose and route of vaccination
    Peter Johannes Holst
    Department of International Health, University of Copenhagen, Copenhagen, Denmark
    J Immunol 184:4431-9. 2010
    ..These findings indicate that the localization of the adenoviral inoculum and not the total Ag load determines the quality of the CD8(+) T cell response induced with adenoviral vaccines...
  6. pmc Metformin stimulates FGF21 expression in primary hepatocytes
    Eva B Nygaard
    Department of Pharmacology and Pharmacotherapy, University of Copenhagen, 2100 Copenhagen, Denmark
    Exp Diabetes Res 2012:465282. 2012
    ..As FGF21 therapy normalizes blood glucose in animal models of type 2 diabetes, the induction of hepatic FGF21 by metformin might play an important role in metformin's antidiabetic effect...