S R Ostrowski

Summary

Affiliation: University of Copenhagen
Country: Denmark

Publications

  1. pmc 2B4 expression on natural killer cells increases in HIV-1 infected patients followed prospectively during highly active antiretroviral therapy
    S R Ostrowski
    Department of Infectious Diseases, Rishospitalet, Copenhagen, Denmark
    Clin Exp Immunol 141:526-33. 2005
  2. ncbi Elevated plasma urokinase receptor predicts low birth weight in maternal malaria
    S R Ostrowski
    Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
    Parasite Immunol 29:37-46. 2007
  3. ncbi Plasma levels of intact and cleaved urokinase receptor decrease in HIV-1-infected patients initiating highly active antiretroviral therapy
    S R Ostrowski
    Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
    Scand J Immunol 63:478-86. 2006
  4. ncbi Reduced release of intact and cleaved urokinase receptor in stimulated whole-blood cultures from human immunodeficiency virus-1-infected patients
    S R Ostrowski
    Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
    Scand J Immunol 61:347-56. 2005
  5. ncbi High plasma levels of intact and cleaved soluble urokinase receptor reflect immune activation and are independent predictors of mortality in HIV-1-infected patients
    Sisse Rye Ostrowski
    Department of Infectious Diseases, Rigshospitalet, Copenhagen, DK 2100 Denmark
    J Acquir Immune Defic Syndr 39:23-31. 2005
  6. ncbi Plasma concentrations of soluble urokinase-type plasminogen activator receptor are increased in patients with malaria and are associated with a poor clinical or a fatal outcome
    Sisse R Ostrowski
    Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
    J Infect Dis 191:1331-41. 2005
  7. ncbi Interleukin-6 infusion during human endotoxaemia inhibits in vitro release of the urokinase receptor from peripheral blood mononuclear cells
    S R Ostrowski
    Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
    Scand J Immunol 61:197-206. 2005
  8. ncbi Low-level viremia and proviral DNA impede immune reconstitution in HIV-1-infected patients receiving highly active antiretroviral therapy
    Sisse R Ostrowski
    Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
    J Infect Dis 191:348-57. 2005
  9. doi Residual viraemia in HIV-1-infected patients with plasma viral load <or=20 copies/ml is associated with increased blood levels of soluble immune activation markers
    S R Ostrowski
    Department of Clinical Immunology, Rigshospitalet, Copenhagen, Denmark
    Scand J Immunol 68:652-60. 2008
  10. ncbi Schistosomiasis and infection with human immunodeficiency virus 1 in rural Zimbabwe: systemic inflammation during co-infection and after treatment for schistosomiasis
    Christian Erikstrup
    Department of Clinical Immunology, Aarhus University Hospital, Skejby Sygehus, Aarhus, Denmark
    Am J Trop Med Hyg 79:331-7. 2008

Collaborators

Detail Information

Publications22

  1. pmc 2B4 expression on natural killer cells increases in HIV-1 infected patients followed prospectively during highly active antiretroviral therapy
    S R Ostrowski
    Department of Infectious Diseases, Rishospitalet, Copenhagen, Denmark
    Clin Exp Immunol 141:526-33. 2005
    ..The finding that proviral-DNA and sTNFrII were associated negatively with the concentration of 2B4+ NK cells suggests that immune activation in HIV-1 infected patients receiving HAART influences the target cell recognition by NK cells...
  2. ncbi Elevated plasma urokinase receptor predicts low birth weight in maternal malaria
    S R Ostrowski
    Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
    Parasite Immunol 29:37-46. 2007
    ..If so, measurements of maternal suPAR early in pregnancy might then potentially identify women with increased needs for antenatal care and intervention...
  3. ncbi Plasma levels of intact and cleaved urokinase receptor decrease in HIV-1-infected patients initiating highly active antiretroviral therapy
    S R Ostrowski
    Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
    Scand J Immunol 63:478-86. 2006
    ..The positive correlation with sTNFrII suggests that the individual plasma suPAR forms are linked to immune activation in HIV-1 infection...
  4. ncbi Reduced release of intact and cleaved urokinase receptor in stimulated whole-blood cultures from human immunodeficiency virus-1-infected patients
    S R Ostrowski
    Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
    Scand J Immunol 61:347-56. 2005
    ..Given that high blood levels of suPAR in HIV patients are linked to immune activation, the perturbations in uPAR release in whole-blood cultures from HIV patients may also reflect immune activation...
  5. ncbi High plasma levels of intact and cleaved soluble urokinase receptor reflect immune activation and are independent predictors of mortality in HIV-1-infected patients
    Sisse Rye Ostrowski
    Department of Infectious Diseases, Rigshospitalet, Copenhagen, DK 2100 Denmark
    J Acquir Immune Defic Syndr 39:23-31. 2005
    ..This study investigated plasma levels of suPAR(I-III), suPAR(II-III), and 1-domain suPAR [suPAR(I)] and their predictive value for survival in HIV patients...
  6. ncbi Plasma concentrations of soluble urokinase-type plasminogen activator receptor are increased in patients with malaria and are associated with a poor clinical or a fatal outcome
    Sisse R Ostrowski
    Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
    J Infect Dis 191:1331-41. 2005
    ..This study explored the hypothesis that high plasma concentrations of suPAR are associated with disease severity in malaria...
  7. ncbi Interleukin-6 infusion during human endotoxaemia inhibits in vitro release of the urokinase receptor from peripheral blood mononuclear cells
    S R Ostrowski
    Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
    Scand J Immunol 61:197-206. 2005
    ..The inhibitory effect of IL-6 on endotoxin-mediated uPAR-release in vitro suggests that IL-6 has anti-inflammatory effects on endotoxin-mediated inflammation...
  8. ncbi Low-level viremia and proviral DNA impede immune reconstitution in HIV-1-infected patients receiving highly active antiretroviral therapy
    Sisse R Ostrowski
    Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
    J Infect Dis 191:348-57. 2005
    ..Immunological and virological consequences of low-level viremia in human immunodeficiency virus (HIV) type 1-infected patients receiving highly active antiretroviral therapy (HAART) remain to be determined...
  9. doi Residual viraemia in HIV-1-infected patients with plasma viral load <or=20 copies/ml is associated with increased blood levels of soluble immune activation markers
    S R Ostrowski
    Department of Clinical Immunology, Rigshospitalet, Copenhagen, Denmark
    Scand J Immunol 68:652-60. 2008
    ..The finding that RV was associated with higher pre-HAART plasma viral load suggests that RV is linked to pre-HAART disease progression...
  10. ncbi Schistosomiasis and infection with human immunodeficiency virus 1 in rural Zimbabwe: systemic inflammation during co-infection and after treatment for schistosomiasis
    Christian Erikstrup
    Department of Clinical Immunology, Aarhus University Hospital, Skejby Sygehus, Aarhus, Denmark
    Am J Trop Med Hyg 79:331-7. 2008
    ..Treatment for schistosomiasis caused a decrease in levels of sTNF-rII (P < 0.05) and IL-10 (P < 0.001). Our results indicate that schistosomiasis treatment may attenuate HIV replication by decreasing systemic inflammation...
  11. doi High sCD40L levels early after trauma are associated with enhanced shock, sympathoadrenal activation, tissue and endothelial damage, coagulopathy and mortality
    P I Johansson
    Section for Transfusion Medicine, Capital Region Blood Bank, Copenhagen University Hospital, Copenhagen, Denmark
    J Thromb Haemost 10:207-16. 2012
    ..Soluble CD40L is a platelet-derived mediator that links inflammation, hemostasis and vascular dysfunction...
  12. pmc Blood product ratio in acute traumatic coagulopathy--effect on mortality in a Scandinavian level 1 trauma centre
    Jesper Dirks
    Department of Anesthesia, Centre of Head and Orthopedics, Copenhagen University Hospital, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Scand J Trauma Resusc Emerg Med 18:65. 2010
    ..Several studies report that higher ratios improve survival in massively bleeding patients. Here, the aim was to investigate the potential effect of increased FFP and PLT to RBC on mortality in trauma patients...
  13. ncbi Reduced mortality and CD4 cell loss among carriers of the interleukin-10 -1082G allele in a Zimbabwean cohort of HIV-1-infected adults
    Christian Erikstrup
    Centre for Inflammation and Metabolism, Denmark
    AIDS 21:2283-91. 2007
    ..To evaluate the effect on HIV progression of single nucleotide polymorphisms in promoters of the genes for tumour necrosis factor (TNF)-alpha and interleukin (IL)-10 and known to influence cytokine production...
  14. ncbi Impaired production of cytokines is an independent predictor of mortality in HIV-1-infected patients
    Sisse R Ostrowski
    Department of Infectious Diseases, The Copenhagen Muscle Research Center, Rigshospitalet, Copenhagen, Denmark
    AIDS 17:521-30. 2003
    ..With regard to the natural history of HIV-1 infection this study investigated whether whole-blood culture cytokine production was associated with mortality in HIV-1-infected patients...
  15. ncbi Self-reported fatigue common among optimally treated HIV patients: no correlation with cerebral FDG-PET scanning abnormalities
    Ase B Andersen
    Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    Neuroimmunomodulation 13:69-75. 2006
    ....
  16. ncbi Soluble urokinase receptor levels in plasma during 5 years of highly active antiretroviral therapy in HIV-1-infected patients
    Sisse R Ostrowski
    Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
    J Acquir Immune Defic Syndr 35:337-42. 2004
    ..The present data indicate that the circulating suPAR level is linked to inflammation in untreated as well as HAART-treated HIV-1-infected patients...
  17. ncbi A low level of CD4+CD28+ T cells is an independent predictor of high mortality in human immunodeficiency virus type 1-infected patients
    Sisse R Ostrowski
    Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
    J Infect Dis 187:1726-34. 2003
    ..If our results are confirmed in other studies, coexpression of CD28 on CD4(+) cells may be a useful marker to evaluate HIV progression...
  18. doi Thromboembolic complications in Fontan patients: population-based prevalence and exploration of the etiology
    L Idorn
    Department of Cardiology, Rigshospitalet, Blegdamsvej 9, Section 2014, 2100 Copenhagen, Denmark
    Pediatr Cardiol 34:262-72. 2013
    ....
  19. doi Soluble urokinase plasminogen activator receptor during allogeneic stem cell transplantation
    E Haastrup
    Department of Clinical Immunology, The Blood Bank, The National University Hospital, Copenhagen, Denmark
    Scand J Immunol 73:325-9. 2011
    ..Further, the data indicated that increased suPAR levels may be associated with increased mortality, suggesting suPAR as a candidate for further studies as an outcome predictor in SCT...
  20. ncbi Elevated levels of soluble urokinase receptor in serum from mycobacteria infected patients: still looking for a marker of treatment efficacy
    S R Ostrowski
    Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
    Scand J Infect Dis 38:1028-32. 2006
    ..This may reflect that significant inflammatory activity is continuing for more than 6 months in patients with extrapulmonary mycobacterial infections, despite adequate anti-tuberculosis treatment...
  21. pmc Cerebral FDG-PET scanning abnormalities in optimally treated HIV patients
    Ase B Andersen
    Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    J Neuroinflammation 7:13. 2010
    ....
  22. ncbi Exercise and IL-6 infusion inhibit endotoxin-induced TNF-alpha production in humans
    Rebecca Starkie
    Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Denmark
    FASEB J 17:884-6. 2003
    ..Hence, these data provide the first experimental evidence that physical activity mediates antiinflammatory activity and suggest that the mechanism include IL-6, which is produced by and released from exercising muscles...