Research Topics
| L NyboSummaryAffiliation: University of Copenhagen Country: Denmark Publications
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Detail Information
Publications
Effects of hyperthermia on cerebral blood flow and metabolism during prolonged exercise in humansLars Nybo
Department of Human Physiology, Institute of Exercise and Sport Sciences, University of Copenhagen, Denmark
J Appl Physiol 93:58-64. 2002....- Cerebral ammonia uptake and accumulation during prolonged exercise in humansLars Nybo
Department of Human Physiology, Institute of Exercise and Sport Sciences, August Krogh Institute, Universitetsparken 13, DK 2100 Copenhagen Ø, Denmark
J Physiol 563:285-90. 2005..The results let us suggest that during prolonged exercise the cerebral uptake and accumulation of ammonia may provoke fatigue, e.g. by affecting neurotransmitter metabolism... - Inadequate cerebral oxygen delivery and central fatigue during strenuous exerciseLars Nybo
Institute of Exercise and Sport Sciences and Department of Anaesthesia, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Exerc Sport Sci Rev 35:110-8. 2007.... - Exercise and heat stress: cerebral challenges and consequencesLars Nybo
Department of Human Physiology, Institute of Exercise and Sport Sciences, August Krogh Institute, Universitetsparken 13, DK 2100 Copenhagen Ø, Denmark
Prog Brain Res 162:29-43. 2007..The complexity of brain fatigue response is discussed based on our own investigations and in the light of recent literature... - Hyperthermia and fatigueLars Nybo
Department of Human Physiology, Institute of Exercise and Sport Sciences, University of Copenhagen, Universitetsparken 13, Copenhagen Ø, Denmark
J Appl Physiol 104:871-8. 2008..Fatigue is an integrated phenomenon, and psychological factors, including the anticipation of fatigue, should not be neglected and the interaction between central and peripheral physiological factors also needs to be considered... - Impact of carbohydrate supplementation during endurance training on glycogen storage and performanceL Nybo
Institute of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark
Acta Physiol (Oxf) 197:117-27. 2009..Therefore, we investigated how chronic training responses are affected by glucose ingestion... - Cerebral perturbations provoked by prolonged exerciseLars Nybo
Department of Human Physiology, Institute of Exercise and Sport Sciences, August Krogh Institute, Universitetsparken 13, DK 2100 Copenhagen, Denmark
Prog Neurobiol 72:223-61. 2004..Therefore, strenuous exercise is a challenge not only to the cardiorespiratory and locomotive systems but also to the brain... - Neurohumoral responses during prolonged exercise in humansLars Nybo
Department of Human Physiology, Institute of Exercise and Sport Sciences, August Krogh Institute, DK 2100 Copenhagen, Denmark
J Appl Physiol 95:1125-31. 2003.... - CNS fatigue and prolonged exercise: effect of glucose supplementationLars Nybo
Department of Human Physiology, Institute of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark
Med Sci Sports Exerc 35:589-94. 2003..This study investigated whether CNS activation of the skeletal muscles was affected by prolonged exercise with or without glucose supplementation... - Interleukin-6 release from the human brain during prolonged exerciseLars Nybo
Department of Human Physiology, Institute of Exercise and Sport Sciences, University of Copenhagen, Denmark
J Physiol 542:991-5. 2002..In conclusion, IL-6 is released from the brain during prolonged exercise in humans and it appears that the duration of the exercise rather than the increase in body temperature dictates the cerebral IL-6 response... - Hyperthermia and central fatigue during prolonged exercise in humansL Nybo
Department of Human Physiology, Institute of Exercise and Sport Sciences, University of Copenhagen, DK 2200 Copenhagen Ø, Denmark
J Appl Physiol 91:1055-60. 2001..In conclusion, these data demonstrate that the ability to generate force during a prolonged MVC is attenuated with hyperthermia, and the impaired performance is associated with a reduction in the voluntary activation percentage... - Perceived exertion is associated with an altered brain activity during exercise with progressive hyperthermiaL Nybo
Department of Human Physiology, Institute of Exercise and Sport Sciences, University of Copenhagen, DK 2100 Copenhagen, Denmark
J Appl Physiol 91:2017-23. 2001.... - Inadequate heat release from the human brain during prolonged exercise with hyperthermiaLars Nybo
Department of Human Physiology, Institute of Exercise and Sport Sciences, University of Copenhagen, Denmark
J Physiol 545:697-704. 2002..20 +/- 0.06 J g(-1) min(-1). The present results indicate that the average brain temperature is at least 0.2 degrees C higher than that of the body core during exercise with or without hyperthermia... - Cycling in the heat: performance perspectives and cerebral challengesL Nybo
Department of Exercise and Sport Sciences, Section of Human Physiology, University of Copenhagen, Copenhagen, Denmark
Scand J Med Sci Sports 20:71-9. 2010.... - Recreational soccer is an effective health-promoting activity for untrained menP Krustrup
University of Copenhagen, Department of Exercise and Sport Sciences, Copenhagen Muscle Research Centre, The August Krogh Building, Universitetsparken 13, Copenhagen 2100 Ø, Denmark
Br J Sports Med 43:825-31. 2009.... - Positive performance and health effects of a football training program over 12 weeks can be maintained over a 1-year period with reduced training frequencyM B Randers
Department of Exercise and Sport Sciences, Section of Human Physiology, University of Copenhagen, Copenhagen, Denmark
Scand J Med Sci Sports 20:80-9. 2010.... - Performance enhancements and muscular adaptations of a 16-week recreational football intervention for untrained womenJ Bangsbo
Department of Exercise and Sport Sciences, Section of Human Physiology, University of Copenhagen, Copenhagen, Denmark
Scand J Med Sci Sports 20:24-30. 2010..Thus, football can be used as an activity to elevate the physical capacity of untrained women... - Cerebral oxygenation is reduced during hyperthermic exercise in humansP Rasmussen
Department of Anaesthesia, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Acta Physiol (Oxf) 199:63-70. 2010..Heat stress challenges exercise capacity as expressed by increased rating of perceived exertion (RPE)... - Beneficial effects of recreational football on the cardiovascular risk profile in untrained premenopausal womenP Krustrup
Department of Exercise and Sport Sciences, Section of Human Physiology, Copenhagen Muscle Research Centre, Section of Human Physiology, University of Copenhagen, Copenhagen, Denmark
Scand J Med Sci Sports 20:40-9. 2010..In conclusion, regular recreational football training has significant favorable effects on the cardiovascular risk profile in untrained premenopausal women and is at the least as efficient as continuous running... - Middle cerebral artery blood velocity is reduced with hyperthermia during prolonged exercise in humansL Nybo
Department of Human Physiology, Institute of Exercise and Sport Sciences, University of Copenhagen, Denmark
J Physiol 534:279-86. 2001..5. The present results demonstrate that the development of hyperthermia during prolonged exercise is associated with a marked reduction in MCA V(mean)... - Association between fatigue and failure to preserve cerebral energy turnover during prolonged exerciseL Nybo
Department of Human Physiology, Institute of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark
Acta Physiol Scand 179:67-74. 2003..1 pg g(-1) min(-1) (P < 0.05). CONCLUSIONS: Exercise-induced hypoglycaemia limits the cerebral uptake of glucose, exacerbates exercise, reduces the cerebral metabolic rate of oxygen and attenuates the release of IL-6 from the brain... - Activity profile and physiological response to football training for untrained males and females, elderly and youngsters: influence of the number of playersM B Randers
Department of Exercise and Sport Sciences, Section of Human Physiology, University of Copenhagen, Copenhagen, Denmark
Scand J Med Sci Sports 20:14-23. 2010..Thus, small-sided football games appear to have the potential to create physiological adaptations and improve performance with regular training for a variety of study groups... - Effect of two different intense training regimens on skeletal muscle ion transport proteins and fatigue developmentMagni Mohr
Copenhagen Muscle Research Centre, Institute of Exercise and Sport Sciences, Universitetsparken 13, DK 2100 Copenhagen Ø, Denmark
Am J Physiol Regul Integr Comp Physiol 292:R1594-602. 2007..Adaptations with training do have an effect on the metabolic response to exercise and specific improvement in work capacity... - Enhanced cerebral CO2 reactivity during strenuous exercise in manP Rasmussen
Department of Human Physiology, Institute of Exercise and Sports Sciences, University of Copenhagen, Denmark
Eur J Appl Physiol 96:299-304. 2006..The results suggest that during exercise changes in cerebral blood flow are dominated by the arterial carbon dioxide tension... - Recreational football as a health promoting activity: a topical reviewP Krustrup
Department of Exercise and Sport Sciences, Section of Human Physiology, University of Copenhagen, Copenhagen, Denmark
Scand J Med Sci Sports 20:1-13. 2010..Taken together, recreational football appears to effectively stimulate musculoskeletal, metabolic and cardiovascular adaptations of importance for health and thereby reduces the risk of developing life-style diseases... - Reduced volume but increased training intensity elevates muscle Na+-K+ pump alpha1-subunit and NHE1 expression as well as short-term work capacity in humansF Marcello Iaia
Department of Exercise and Sport Sciences, Section of Human Physiology, Copenhagen Muscle Research Center, University of Copenhagen, Copenhagen, Denmark
Am J Physiol Regul Integr Comp Physiol 294:R966-74. 2008..Furthermore, performance during intense exercise can be improved and endurance performance maintained even with a reduction in training volume if the intensity of training is very high... - Cerebral metabolism is influenced by muscle ischaemia during exercise in humansMads K Dalsgaard
Department of Anaesthesia and The Copenhagen Muscle Research Centre, Rigshospitalet, University of Copenhagen, Denmark
Exp Physiol 88:297-302. 2003..5 +/- 0.3 (P < 0.05). The results support the hypothesis that during exercise, cerebral metabolism is influenced both by the mental effort to exercise and by sensory input from skeletal muscles... - Cerebral changes during exercise in the heatBodil Nielsen
Institute of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark
Sports Med 33:1-11. 2003..The causal relationship between the circulatory changes, the EEG changes and the hyperthermia-induced central fatigue is at the present not well understood and future studies should focus on this aspect... - CNS fatigue provoked by prolonged exercise in the heatLars Nybo
Section of Human Physiology, Department of Exercise and Sport Sciences, University of Copenhagen, Universitetsparken 13, DK 2100 Copenhagen O, Denmark
Front Biosci (Elite Ed) 2:779-92. 2010.... - Environmental heat stress, hyperammonemia and nucleotide metabolism during intermittent exerciseMagni Mohr
Institute of Exercise and Sport Sciences, Department of Human Physiology, August Krogh Institute, University of Copenhagen, Universitetsparken 13, 2100, Copenhagen, Denmark
Eur J Appl Physiol 97:89-95. 2006.... - Reduced volume and increased training intensity elevate muscle Na+-K+ pump alpha2-subunit expression as well as short- and long-term work capacity in humansJens Bangsbo
Department of Exercise and Sport Sciences, Section of Human Physiology, Copenhagen Muscle Research Centre, University of Copenhagen, Copenhagen, Denmark
J Appl Physiol 107:1771-80. 2009.... - Capillary-oxygenation-level-dependent near-infrared spectrometry in frontal lobe of humansPeter Rasmussen
Copenhagen Muscle Research Centre, Department of Anaesthesia, University of Copenhagen, Rigshospitalet, Copenhagen, Denmark
J Cereb Blood Flow Metab 27:1082-93. 2007.... - The Yo-Yo IR2 test: physiological response, reliability, and application to elite soccerPeter Krustrup
Institute of Exercise and Sport Sciences, Department of Human Physiology, August Krogh Institute, University of Copenhagen, Copenhagen, Denmark
Med Sci Sports Exerc 38:1666-73. 2006..To examine the physiological response, reliability, and validity of the Yo-Yo intermittent recovery level 2 test (Yo-Yo IR2)... - Muscle temperature and sprint performance during soccer matches--beneficial effect of re-warm-up at half-timeM Mohr
Department of Human Physiology, Institute of Exercise and Sport Sciences, August Krogh Institute, University of Copenhagen, Universitetsparken 13, DK-2100 Copenhagen, Denmark
Scand J Med Sci Sports 14:156-62. 2004.... - Pro- and anti-angiogenic factors in human skeletal muscle in response to acute exercise and trainingB Hoier
Y Hellsten Department of Exercise and Sport Sciences, University of Copenhagen, Universitetsparken 13, DK 2100 Copenhagen, Denmark
J Physiol 590:595-606. 2012..The lack of effect of training on basal muscle VEGF protein levels and VEGF secretion during exercise suggests that increased VEGF levels are not a prerequisite for exercise-induced capillary growth in healthy muscle... - Effect of 2-wk intensified training and inactivity on muscle Na+-K+ pump expression, phospholemman (FXYD1) phosphorylation, and performance in soccer playersMartin Thomassen
Copenhagen Muscle Research Centre, Department of Exercise and Sport Sciences, Section of Human Physiology, University of Copenhagen, Copenhagen, Denmark
J Appl Physiol 108:898-905. 2010..Resting phosphorylation status of the Na(+)-K(+) pump is changed by training and inactivity and may play a role in performance during repeated, intense exercise... - Muscle adaptations and performance enhancements of soccer training for untrained menPeter Krustrup
Department of Exercise and Sport Sciences, Section of Human Physiology, Copenhagen Muscle Research Centre, University of Copenhagen, The August Krogh Building, Universitetsparken 13, Copenhagen 2100, Denmark
Eur J Appl Physiol 108:1247-58. 2010.... - Adipose triglyceride lipase in human skeletal muscle is upregulated by exercise trainingThomas J Alsted
University of Copenhagen, The August Krogh Bldg 13, Universitetsparken, DK, 2100 Copenhagen, Denmark
Am J Physiol Endocrinol Metab 296:E445-53. 2009..These results suggest that ATGL in addition to HSL may be important for human skeletal muscle lipolysis... - Minor amounts of plasma medium-chain fatty acids and no improved time trial performance after consuming lipidsBodil Vistisen
BioCentrum DTU, The Technical University of Denmark, Lyngby, Denmark
J Appl Physiol 95:2434-43. 2003..A higher level of plasma phospholipid fatty acids in the CHO+MLM compared with the CHO group was probably due to endogenous phospholipid release into chylomicrons... - Viewpoint: Fatigue mechanisms determining exercise performance: integrative physiology is systems physiologyLars Nybo
J Appl Physiol 104:1543-4. 2008