Morten H H Nørholm

Summary

Affiliation: University of Copenhagen
Country: Denmark

Publications

  1. pmc Manipulating the genetic code for membrane protein production: what have we learnt so far?
    Morten H H Nørholm
    Center for Biomembrane Research, Department of Biochemistry and Biophysics, Stockholm University, SE 106 91, Sweden
    Biochim Biophys Acta 1818:1091-6. 2012
  2. doi Improved production of membrane proteins in Escherichia coli by selective codon substitutions
    Morten H H Nørholm
    Center for Biomembrane Research, Department of Biochemistry and Biophysics, Stockholm University, SE 106 91 Stockholm, Sweden
    FEBS Lett 587:2352-8. 2013
  3. pmc Application of split-green fluorescent protein for topology mapping membrane proteins in Escherichia coli
    Stephen Toddo
    Department of Biochemistry and Biophysics, Center for Biomembrane Research, Stockholm University, SE 10691 Sweden
    Protein Sci 21:1571-6. 2012
  4. pmc Flanking residues help determine whether a hydrophobic segment adopts a monotopic or bitopic topology in the endoplasmic reticulum membrane
    Morten H H Nørholm
    Center for Biomembrane Research, Department of Biochemistry and Biophysics, Stockholm University, SE 106 91 Stockholm, Sweden
    J Biol Chem 286:25284-90. 2011
  5. doi Converting a marginally hydrophobic soluble protein into a membrane protein
    Morten H H Nørholm
    Department of Biochemistry and Biophysics, Center for Biomembrane Research, Stockholm University, SE 106 91 Stockholm, Sweden
    J Mol Biol 407:171-9. 2011

Detail Information

Publications5

  1. pmc Manipulating the genetic code for membrane protein production: what have we learnt so far?
    Morten H H Nørholm
    Center for Biomembrane Research, Department of Biochemistry and Biophysics, Stockholm University, SE 106 91, Sweden
    Biochim Biophys Acta 1818:1091-6. 2012
    ..This article is part of a Special Issue entitled: Protein Folding in Membranes...
  2. doi Improved production of membrane proteins in Escherichia coli by selective codon substitutions
    Morten H H Nørholm
    Center for Biomembrane Research, Department of Biochemistry and Biophysics, Stockholm University, SE 106 91 Stockholm, Sweden
    FEBS Lett 587:2352-8. 2013
    ..We conclude that coding sequences can be re-wired for high-level protein expression by selective engineering of the 5' coding sequence with synonymous codons, thus circumventing the need to consider whole sequence optimization. ..
  3. pmc Application of split-green fluorescent protein for topology mapping membrane proteins in Escherichia coli
    Stephen Toddo
    Department of Biochemistry and Biophysics, Center for Biomembrane Research, Stockholm University, SE 10691 Sweden
    Protein Sci 21:1571-6. 2012
    ..Here, we show that the bimolecular split-green fluorescent protein complementation system can overcome this limitation and can be used to determine the location of both the N- and C-termini of inner membrane proteins in Escherichia coli...
  4. pmc Flanking residues help determine whether a hydrophobic segment adopts a monotopic or bitopic topology in the endoplasmic reticulum membrane
    Morten H H Nørholm
    Center for Biomembrane Research, Department of Biochemistry and Biophysics, Stockholm University, SE 106 91 Stockholm, Sweden
    J Biol Chem 286:25284-90. 2011
    ..In addition, we find that charged flanking residues as well as proline residues embedded in the hydrophobic segment are important determinants of monotopic versus bitopic topology...
  5. doi Converting a marginally hydrophobic soluble protein into a membrane protein
    Morten H H Nørholm
    Department of Biochemistry and Biophysics, Center for Biomembrane Research, Stockholm University, SE 106 91 Stockholm, Sweden
    J Mol Biol 407:171-9. 2011
    ....