Research Topics
Genomes and Genes
| Søren NielsenSummaryAffiliation: University of Aarhus Country: Denmark Publications
| Collaborators
|
Detail Information
Publications
Increased renal sodium absorption by inhibition of prostaglandin synthesis during fasting in healthy man. A possible role of the epithelial sodium channelsThomas G Lauridsen
Department of Medical Research, Holstebro Hospital, Denmark
BMC Nephrol 11:28. 2010....- Aquaporin-11: a channel protein lacking apparent transport function expressed in brainDaniel A Gorelick
Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, USA
BMC Biochem 7:14. 2006..Two recently described aquaporins, numbers 11 and 12, appear to be more distantly related to the other mammalian aquaporins and aquaglyceroporins... 
Aquaporins in the kidney: from molecules to medicineSøren Nielsen
The Water and Salt Research Center, Institute of Anatomy, and Institute of Experimental Clinical Research, University of Aarhus, Aarhus, Denmark
Physiol Rev 82:205-44. 2002..Continued analysis of the aquaporins is providing detailed molecular insight into the fundamental physiology and pathophysiology of water balance and water balance disorders...- Renal aquaporins: an overviewS Nielsen
Water and Salt Research Centre, University of Aarhus, Denmark
BJU Int 90:1-6. 2002 - Regulation and dysregulation of aquaporins in water balance disordersS Nielsen
The Water and Salt Research Center, University of Aarhus, Aarhus C, Denmark
J Intern Med 261:53-64. 2007.... - COX-2 inhibition prevents downregulation of key renal water and sodium transport proteins in response to bilateral ureteral obstructionRikke Nørregaard
The Water and Salt Research Center, University of Aarhus, Denmark
Am J Physiol Renal Physiol 289:F322-33. 2005..These data indicate that COX-2 may be an important factor contributing to the impaired renal water and sodium handling in response to BUO... 
Ureter obstruction alters expression of renal acid-base transport proteins in rat kidneyGuixian Wang
The Water and Salt Research Center, Aarhus University, Aarhus, Denmark
Am J Physiol Renal Physiol 295:F497-506. 2008....- Changes in cellular composition of kidney collecting duct cells in rats with lithium-induced NDIBirgitte Mønster Christensen
Water and Salt Research Center, Institute of Anatomy, University of Aarhus, DK 8000 Aarhus, Denmark
Am J Physiol Cell Physiol 286:C952-64. 2004..These effects are likely to be important in lithium-induced nephrogenic diabetes insipidus... - Increased expression and apical targeting of renal ENaC subunits in puromycin aminonucleoside-induced nephrotic syndrome in ratsSoo Wan Kim
The Water and Salt Research Center, University of Aarhus, DK 8000 Aarhus C, Denmark
Am J Physiol Renal Physiol 286:F922-35. 2004..The decreased abundance of NHE3, BSC-1, TSC, and Na-K-ATPase may play a compensatory role to promote sodium excretion... - Long-term aldosterone treatment induces decreased apical but increased basolateral expression of AQP2 in CCD of rat kidneySophie de Seigneux
The Water and Salt Research Center, University of Aarhus, DK 8000 Aarhus C, Denmark
Am J Physiol Renal Physiol 293:F87-99. 2007..The increased basolateral expression of AQP2 induced by aldosterone may play a significant role in water metabolism in conditions with increased sodium reabsorption in the CCD... - Increased apical targeting of renal epithelial sodium channel subunits and decreased expression of type 2 11beta-hydroxysteroid dehydrogenase in rats with CCl4-induced decompensated liver cirrhosisSoo Wan Kim
The Water and Salt Research Center, University of Aarhus, Aarhus, Denmark DK 8000
J Am Soc Nephrol 16:3196-210. 2005..In conclusion, increased apical targeting of ENaC subunits combined with diminished abundance of 11betaHSD2 in the DCT2, CNT, and cortical collecting duct is likely to play a role in the sodium retaining stage of liver cirrhosis... - NBCn1 is a basolateral Na+-HCO3- cotransporter in rat kidney inner medullary collecting ductsJeppe Praetorius
The Water and Salt Research Ctr, University of Aarhus, Wilhelm Meyers Allé Bldg 233, 8000 Aarhus C, Denmark
Am J Physiol Renal Physiol 286:F903-12. 2004..In conclusion, NBCn1 is a basolateral Na(+)-HCO(3)(-) cotransporter of IMCD cells and is differentially regulated in IMCD and medullary thick ascending limb... - Lithium treatment induces a marked proliferation of primarily principal cells in rat kidney inner medullary collecting ductBirgitte Mønster Christensen
The Water and Salt Research Center, Institute of Anatomy, University of Aarhus, DK 8000 Aarhus, Denmark
Am J Physiol Renal Physiol 291:F39-48. 2006..This is likely to contribute to the remodeling of the collecting duct after Li treatment... - Cyclooxygenase 2 inhibition exacerbates AQP2 and pAQP2 downregulation independently of V2 receptor abundance in the postobstructed kidneyAnja M Jensen
The Water and Salt Research Center, Institute of Clinical Medicine, University of Aarhus, Aarhus, Denmark
Am J Physiol Renal Physiol 298:F941-50. 2010..The results indicate that COX-2 inhibition does not mimic AT1R blockade-mediated effects and that AT1R-mediated AQP2 regulation in the postobstructed kidney collecting duct is independent of COX-2 induction... - Angiotensin II regulates V2 receptor and pAQP2 during ureteral obstructionAnja M Jensen
The Water and Salt Research Center, Institute of Clinical Medicine, Univ of Aarhus, Dept of Clinical Physiology and Nuclear Medicine, Aarhus Univ Hospital Skejby, Brendstrupgaardsvej, DK 8200 Aarhus N, Denmark
Am J Physiol Renal Physiol 296:F127-34. 2009..In addition, we have shown that angiotensin II regulates the V2 receptor complex and pS256-AQP2 in postobstructive kidney IM, probably by stimulating cAMP generation... - Altered expression of renal acid-base transporters in rats with lithium-induced NDIYoung Hee Kim
The Water and Salt Research Center, Institute of Anatomy, University of Aarhus, DK 8000 Aarhus C, Denmark
Am J Physiol Renal Physiol 285:F1244-57. 2003..This is likely to represent direct or compensatory effects to increase the capacity for HCO3- reabsorption, NH4+ reabsorption, and proton secretion to prevent the development of systemic metabolic acidosis... - Glomerular and tubular function during AT1 receptor blockade in pigs with neonatal induced partial ureteropelvic obstructionAnni Eskild-Jensen
Department of Clinical Physiology and Nuclear Medicine, University of Aarhus, Denmark
Am J Physiol Renal Physiol 292:F921-9. 2007..This may have diagnostic potential in children with suspected congenital obstruction. Our results also demonstrate compromised tubular functions in response to chronic PUUO despite preservation of glomerular function... - Biphasic effects of ANP infusion in conscious, euvolumic rats: roles of AQP2 and ENaC traffickingWeidong Wang
The Water and Salt Research Center, Institute of Anatomy, University of Aarhus, DK 8000 Aarhus C, Denmark
Am J Physiol Renal Physiol 290:F530-41. 2006..The increased targeting of ENaC and AQP2 likely represents direct or compensatory effects to increase sodium and water reabsorption and to prevent volume depletion in response to prolonged ANP infusion... - Axial heterogeneity in basolateral AQP2 localization in rat kidney: effect of vasopressinBirgitte Mønster Christensen
The Water and Salt Research Center, Institute of AnatomyUniversity of DK 8000 Aarhus, Denmark
Am J Physiol Renal Physiol 284:F701-17. 2003..Moreover, acute V(2)-receptor antagonist treatment did not cause retrieval of AQP2 from the BLM. In contrast, long-term dDAVP treatment caused a major increase in AQP2 expression in the BLM in CCD... - Immunolocalization of AQP-5 in rat parotid and submandibular salivary glands after stimulation or inhibition of secretion in vivoVeronika Gresz
Water and Salt Research Center, Institute of Anatomy, University of Aarhus, DK 8000 Aarhus C, Denmark
Am J Physiol Gastrointest Liver Physiol 287:G151-61. 2004.... - Unilateral ureteral obstruction alters expression of acid-base transporters in rat kidneyGuixian Wang
Water and Salt Research Center, University of Aarhus, Aarhus, Denmark
J Urol 182:2964-73. 2009..To clarify the molecular mechanisms of these defects we examined expression levels of key acid-base transporters along the renal nephron segments and collecting duct... - Rapid and segmental specific dysregulation of AQP2, S256-pAQP2 and renal sodium transporters in rats with LPS-induced endotoxaemiaEmma T B Olesen
The Water and Salt Research Centre, Institute of Anatomy, University of Aarhus, Aarhus, Denmark
Nephrol Dial Transplant 24:2338-49. 2009..Next, we aimed to examine the changes of iNOS expression and activated macrophage infiltration in the kidney and the effects of iNOS inhibition on AQP2 and NKCC2 expression in LPS rats... - Increased expression but not targeting of ENaC in adrenalectomized rats with PAN-induced nephrotic syndromeSophie de Seigneux
The Water and Salt Research Center, Bldg 233 234, University of Aarhus, and Institute of Clinical Medicine, Aarhus University Hospital, Denmark
Am J Physiol Renal Physiol 291:F208-17. 2006..Am J Physiol Renal Physiol 286: F922-F935, 2004) is caused by aldosterone and that development of sodium retention can occur in the absence of aldosterone in NS... - Age-dependent renal expression of acid-base transporters in neonatal ureter obstructionGuixian Wang
The Water and Salt Research Center, University of Aarhus, Aarhus C, Denmark
Pediatr Nephrol 24:1487-500. 2009.... - Aldosterone increases urine production and decreases apical AQP2 expression in rats with diabetes insipidusJakob Nielsen
The Water and Salt Research Center, Institute of Anatomy, University of Aarhus, DK 8000 Aarhus, Denmark
Am J Physiol Renal Physiol 290:F438-49. 2006..This study shows that aldosterone treatment perturbs diabetes insipidus and is associated with AQP2 redistribution in CNT and iCCD likely mediated by the spironolactone-sensitive mineralocorticoid receptor... - Altered expression of COX-1, COX-2, and mPGES in rats with nephrogenic and central diabetes insipidusPrimoz Kotnik
The Water and Salt Research Center, University of Aarhus, DK 8000 Aarhus C, Denmark
Am J Physiol Renal Physiol 288:F1053-68. 2005..These results identify markedly reduced expression of COX-1, COX-2, and mPGES in IM in lithium-induced NDI. Furthermore, there were major changes in the expression of COX-1, COX-2, and mPGES in rats with CDI... - Segment-specific ENaC downregulation in kidney of rats with lithium-induced NDIJakob Nielsen
The Water and Salt Research Center, Institute of Anatomy Bldg 233, University of Aarhus, DK 8000 Aarhus, Denmark
Am J Physiol Renal Physiol 285:F1198-209. 2003.... - COX-2 activity transiently contributes to increased water and NaCl excretion in the polyuric phase after release of ureteral obstructionRikke Nørregaard
The Water and Salt Research Center, University of Aarhus, DK 8200 Aarhus N, Denmark
Am J Physiol Renal Physiol 292:F1322-33. 2007.... - AQP7 is localized in capillaries of adipose tissue, cardiac and striated muscle: implications in glycerol metabolismMariusz T Skowronski
The Water and Salt Research Center, Institute of Anatomy, University of Aarhus, DK 8000 Aarhus C, Denmark
Am J Physiol Renal Physiol 292:F956-65. 2007..In conclusion, AQP7 is expressed in capillary endothelia of adipose tissue (and cardiac and striated muscle) and is upregulated in WAT in response to S-DM supporting its role in glycerol metabolism... - Altered expression of epithelial sodium channel in rats with bilateral or unilateral ureteral obstructionChunling Li
The Water and Salt Research Center, University of Aarhus, DK 8230 Aarhus N, Denmark
Am J Physiol Renal Physiol 293:F333-41. 2007..These results suggest that altered expression of alpha-, beta-, and gamma-ENaC may contribute to impaired renal sodium and water handling in response to ureteral obstruction... - Defective glycerol metabolism in aquaporin 9 (AQP9) knockout miceAleksandra M Rojek
The Water and Salt Research Center, University of Aarhus, DK 8000 Aarhus C, Denmark
Proc Natl Acad Sci U S A 104:3609-14. 2007..Thus, AQP9 is important for hepatic glycerol metabolism and may play a role in glycerol and glucose metabolism in diabetes mellitus... - Renal compensation to chronic hypoxic hypercapnia: downregulation of pendrin and adaptation of the proximal tubuleSophie de Seigneux
The Water and Salt Research Center, Institute of Anatomy, Bldg 1234, Univ of Aarhus, DK 8000 Aarhus C, Denmark
Am J Physiol Renal Physiol 292:F1256-66. 2007.... - Furosemide increases water content in renal tissueMichael Pedersen
MR Research Centre, Aarhus University Hospital, University of Aarhus, Aarhus, Denmark
Am J Physiol Renal Physiol 292:F1645-51. 2007.... - Functional up-regulation of basolateral Na+-dependent HCO3- transporter NBCn1 in medullary thick ascending limb of K+-depleted ratsJakob K Jakobsen
Institute of Physiology, University of Aarhus, Ole Worms Alle 160, 8000 Aarhus C, Denmark
Pflugers Arch 448:571-8. 2004..They also indicate that it is the delivery of luminal NH(4)(+) rather than systemic changes of pH that determine the expression of NBCn1... - Increased apical targeting of renal ENaC subunits and decreased expression of 11betaHSD2 in HgCl2-induced nephrotic syndrome in ratsSoo Wan Kim
The Water and Salt Research Center, Bldg 233 234, University of Aarhus, DK 8000 Aarhus C, Denmark
Am J Physiol Renal Physiol 290:F674-87. 2006..The decreased abundance of NHE3, NKCC2, NCC, and Na-K-ATPase may play a compensatory role in promoting sodium excretion... - Reduced renal expression of AQP2, p-AQP2 and AQP3 in haemorrhagic shock-induced acute renal failureHong Gong
The Water and Salt Research Center, Institute of Anatomy, University of Aarhus, Building 233, Wilhelm Meyers Alle, DK 8000 Aarhus C, Denmark
Nephrol Dial Transplant 18:2551-9. 2003.... - Acute regulation of aquaporin-2 phosphorylation at Ser-264 by vasopressinRobert A Fenton
The Water and Salt Research Center, Institute of Anatomy, University of Aarhus, DK 8000 Aarhus C, Denmark
Proc Natl Acad Sci U S A 105:3134-9. 2008..Overall, our results are consistent with a dynamic effect of AVP on the phosphorylation and subcellular distribution of AQP2... - Downregulation of renal aquaporins in response to unilateral ureteral obstructionChunling Li
The Water and Salt Research Center, University of Aarhus, DK 8000 Aarhus C, Denmark
Am J Physiol Renal Physiol 284:F1066-79. 2003.... - Similar VLDL-TG storage in visceral and subcutaneous fat in obese and lean womenEsben Søndergaard
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Diabetes 60:2787-91. 2011..Differential lipid redistribution through lipoproteins may affect body fat distribution. This is the first study to investigate VLDL-triglyceride (VLDL-TG) storage in visceral fat... - AE2 isoforms in rat kidney: immunohistochemical localization and regulation in response to chronic NH4Cl loadingSebastian Frische
The Water and Salt Research Center, Bldg 233 234, Univ of Aarhus, DK 8000 Aarhus C, Denmark
Am J Physiol Renal Physiol 286:F1163-70. 2004..The regulation following NH(4)Cl loading of AE2b in the cTAL suggests a role for AE2 in transepithelial bicarbonate reabsorption in this segment... - Neonatal ureteral obstruction alters expression of renal sodium transporters and aquaporin water channelsYimin Shi
Institute of Experimental Clinical Research, Aarhus University, Aarhus, Denmark
Kidney Int 66:203-15. 2004..Recently, we demonstrated that ureteral obstruction in adult rats is associated with reduction in the abundance of renal aquaporins (AQPs) and renal sodium transporters, which paralleled an impaired urinary concentrating capacity... - Increased expression of ENaC subunits and increased apical targeting of AQP2 in the kidneys of spontaneously hypertensive ratsSoo Wan Kim
The Water and Salt Research Center, University of Aarhus, DK 8000 Aarhus C, Denmark
Am J Physiol Renal Physiol 289:F957-68. 2005..These results suggest that the increased protein abundance of ENaC subunits as well as the increased apical targeting of AQP2 may contribute to renal sodium and water retention observed during the development of hypertension in SHR... - Impaired insulin-mediated antilipolysis and lactate release in adipose tissue of upper-body obese womenBirgitte Nellemann
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Obesity (Silver Spring) 20:57-64. 2012..So, UBO women were metabolically inflexible with respect to insulins antilipolytic and lactate increasing effects in abdominal adipose tissue. These phenomena are probably both consequences of insulin resistance of adipose tissue... - Regulation of sodium transporters in the thick ascending limb of rat kidney: response to angiotensin IITae Hwan Kwon
The Water and Salt Research Center, University of Aarhus, Denmark
Am J Physiol Renal Physiol 285:F152-65. 2003..In conclusion, increased abundance of NHE3 and BSC-1 in mTAL cells as well as increased NHE3 in the proximal tubule brush border may contribute to enhanced renal Na+ and HCO3 reabsorption in response to ANG II... - Increased renal adrenomedullin expression in rats with ureteral obstructionRikke Nørregaard
The Water and Salt Research Center, Clinical Institute, Univ of Aarhus, Dept of Clinical Physiology and Nuclear Medicine, Aarhus Univ Hospital Skejby, Brendstrupgaardsvej, DK 8200 Aarhus N, Denmark
Am J Physiol Regul Integr Comp Physiol 296:R185-92. 2009..Hypoxia acting through HIF-1alpha accumulation may be an important pathway for the renal response to ureteral obstruction... - Regulated expression of pendrin in rat kidney in response to chronic NH4Cl or NaHCO3 loadingSebastian Frische
The Water and Salt Research Center, Institute of Anatomy, and Institute of Experimental Clinical Research, University of Aarhus, DK 8000 Aarhus C, Denmark
Am J Physiol Renal Physiol 284:F584-93. 2003.... - Proteomic analysis of lithium-induced nephrogenic diabetes insipidus: mechanisms for aquaporin 2 down-regulation and cellular proliferationJakob Nielsen
Water and Salt Research Center, University of Aarhus, DK 8000 Aarhus C, Denmark
Proc Natl Acad Sci U S A 105:3634-9. 2008..This study provides a comprehensive analysis of the proteins affected by lithium treatment in the IMCD and, as such, provides clues to potential lithium targets in the brain... - Aldosterone-mediated apical targeting of ENaC subunits is blunted in rats with streptozotocin-induced diabetes mellitusHeidi O'Neill
The Water and Salt Research Center, Building 233 234, University of Aarhus, DK 8000 Aarhus C, Denmark
Nephrol Dial Transplant 23:1546-55. 2008.... - Acute peripheral metabolic effects of intraarterial leg infusion of somatostatin in healthy young menThomas Krusenstjerna-Hafstrøm
Department of Internal Medicine and Endocrinology MEA, Aarhus University Hospital, Aarhus C, Denmark
J Clin Endocrinol Metab 96:2581-9. 2011..Evidence suggests that somatostatin not only inhibits the secretion of GH but also suppresses GH action in peripheral tissues... - Molecular expression of SLC4-derived Na+-dependent anion transporters in selected human tissuesHelle Hasager Damkier
The Water and Salt Research Center, Institute of Anatomy, University of Aarhus, Wilhelm Meyers Alle, Bldg 1 234, 8000 Aarhus C, Denmark
Am J Physiol Regul Integr Comp Physiol 293:R2136-46. 2007..In conclusion, the selected human tissues display distinct expression patterns of HCO(3)(-) transporters, which closely resemble that of rodent tissues... - Maintained ENaC trafficking in aldosterone-infused rats during mineralocorticoid and glucocorticoid receptor blockadeJakob Nielsen
The Water and Salt Research Center, Institute of Anatomy, Aarhus, Denmark
Am J Physiol Renal Physiol 292:F382-94. 2007..We provide new evidence for ENaC trafficking occurring independent of MR and GR activation in aldosterone-infused rats... - Candesartan prevents long-term impairment of renal function in response to neonatal partial unilateral ureteral obstructionSukru Oguzkan Topcu
The Water and Salt Research Ctr, Institute of Clinical Medicine, University of Aarhus, DK 8200 Aarhus, Denmark
Am J Physiol Renal Physiol 292:F736-48. 2007.... - Aquaporin-9 and urea transporter-A gene deletions affect urea transmembrane passage in murine hepatocytesSabina Jelen
The Water and Salt Research Center, Department of Biomedicine, Aarhus University, Aarhus, Denmark
Am J Physiol Gastrointest Liver Physiol 303:G1279-87. 2012..We conclude that AQP9 and unidentified UT-A urea channels constitute primary but redundant urea facilitators in murine hepatocytes... - Postabsorptive VLDL-TG fatty acid storage in adipose tissue in lean and obese womenBirgitte Nellemann
Medical Department M, Aarhus University Hospital, Aarhus, Denmark
Obesity (Silver Spring) 18:1304-11. 2010..We suggest that the differences in VLDL-TG storage in abdominal and femoral fat that occur with progressive obesity are regulated through mechanisms other than LPL activity... - NKCC1 and NHE1 are abundantly expressed in the basolateral plasma membrane of secretory coil cells in rat, mouse, and human sweat glandsLene N Nejsum
The Water and Salt Research Center, Institute of Anatomy, Univ of Aarhus, DK 8000 Aarhus, Denmark
Am J Physiol Cell Physiol 289:C333-40. 2005.... - Targeted disruption of the Cl-/HCO3- exchanger Ae2 results in osteopetrosis in miceKaj Josephsen
The Water and Salt Research Center, Faculty of Health Sciences, Department of Dental Pathology, Operative Dentistry and Endodontics, School of Dentistry, and Institute of Anatomy, University of Aarhus, DK 8000 Aarhus C, Denmark
Proc Natl Acad Sci U S A 106:1638-41. 2009..Furthermore, osteoclasts in Ae2-/- mice were dramatically enlarged and fail to form the normal ruffled border facing the lacunae. Thus, Ae2 is likely to be an essential component of the bone resorption mechanism in osteoclasts... - Severe urinary concentrating defect in renal collecting duct-selective AQP2 conditional-knockout miceAleksandra Rojek
Water and Salt Research Center, Institute of Anatomy, and Department of Molecular Biology, University of Aarhus, DK 8000 Aarhus C, Denmark
Proc Natl Acad Sci U S A 103:6037-42. 2006..These results demonstrate that AQP2 in CNT is sufficient for postnatal survival and that AQP2 in CD is essential for regulation of body water balance and cannot be compensated for by other mechanisms... - Dysregulation of renal aquaporins and epithelial sodium channel in lithium-induced nephrogenic diabetes insipidusJakob Nielsen
The Water and Salt Research Center, Institute of Anatomy, University of Aarhus, Aarhus C, Denmark
Semin Nephrol 28:227-44. 2008..This includes dysregulation of renal aquaporins, epithelial sodium channel, and acid/base transporters. This review focuses on these issues with the aim to present this in context with clinically relevant features... - Acute growth hormone administration induces antidiuretic and antinatriuretic effects and increases phosphorylation of NKCC2Henrik Dimke
The Water and Salt Research Centre, Institute of Anatomy, University of Aarhus, 8000 Aarhus C, Denmark
Am J Physiol Renal Physiol 292:F723-35. 2007..In conclusion, GH appears to exert its acute antinatriuretic and antidiuretic effects through indirect activation of NKCC2 in the mTAL... - Increased VLDL-triglyceride secretion precedes impaired control of endogenous glucose production in obese, normoglycemic menLars P Sørensen
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Diabetes 60:2257-64. 2011..To assess basal and insulin-mediated VLDL-triglyceride (TG) kinetics and the relationship between VLDL-TG secretion and hepatic insulin resistance assessed by endogenous glucose production (EGP) in obese and lean men... - Basal and insulin mediated VLDL-triglyceride kinetics in type 2 diabetic menLars P Sørensen
Department of Endocrinology and Internal Medicine, University Hospital, Aarhus, Denmark
Diabetes 60:88-96. 2011..The objective was to compare basal and insulin mediated VLDL-TG kinetics, oxidation, and adipose tissue storage in type 2 diabetic and healthy (nondiabetic) men... - Chronic metabolic acidosis upregulates rat kidney Na-HCO cotransporters NBCn1 and NBC3 but not NBC1Tae Hwan Kwon
The Water and Salt Research Center, University of Aarhus, DK 8000 Aarhus C, Denmark
Am J Physiol Renal Physiol 282:F341-51. 2002..The increased abundance of NBCn1 may play a role in the reabsorption of NH in the mTAL and increased NBC3 in reabsorbing HCO... - Cellular and subcellular distribution of the type-2 vasopressin receptor in the kidneyRobert A Fenton
The Water and Salt Research Center, Institute of Anatomy, University of Aarhus, Aarhus, Denmark
Am J Physiol Renal Physiol 293:F748-60. 2007..Confocal microscopy of isolated inner medullary collecting duct tubules showed that the V2R is expressed both intracellularly and in basolateral membrane domains... - Pre-existing renal failure worsens the outcome after intestinal ischaemia and reperfusion in ratsMartin Skott
The Water and Salt Research Centre, University of Aarhus, Aarhus, Denmark
Nephrol Dial Transplant 25:3509-17. 2010..We aim to examine whether CKD increases the morbidity and mortality of AKI induced by intestinal ischaemia and reperfusion (I-I/R)... - Ion transporters in secretory and cyclically modulating ameloblasts: a new hypothesis for cellular control of preeruptive enamel maturationKaj Josephsen
Department of Dental Pathology, Operative Dentistry, and Endodontics, Aarhus University, Aarhus, Denmark
Am J Physiol Cell Physiol 299:C1299-307. 2010.... - Bidirectional regulation of AQP2 trafficking and recycling: involvement of AQP2-S256 phosphorylationLene N Nejsum
The Water and Salt Research Center, University of Aarhus, DK 8000 Aarhus, Denmark
Am J Physiol Renal Physiol 288:F930-8. 2005.... - A current view of the mammalian aquaglyceroporinsAleksandra Rojek
Water and Salt Research Center, Institute of Anatomy, University of Aarhus, Aarhus C, Denmark
Annu Rev Physiol 70:301-27. 2008..This review comprehensively discusses the recent discoveries in the field of aquaglyceroporins, alongside a brief overview of the so-called unorthodox aquaporins... - Peroxisome proliferator-activated receptor gamma agonism modifies the effects of growth hormone on lipolysis and insulin sensitivityMorten B Krag
Medical Department M, Aarhus University Hospital, Aarhus Sygehus, Aarhus C, Denmark
Clin Endocrinol (Oxf) 69:452-61. 2008.... - Functional requirement of aquaporin-5 in plasma membranes of sweat glandsLene N Nejsum
The Water and Salt Research Center and the Department of Human Genetics, University of Aarhus, DK 8000 Aarhus, Denmark
Proc Natl Acad Sci U S A 99:511-6. 2002.... - Reduction of ischemic stroke in rat brain by alpha melanocyte stimulating hormoneGang Chen
MR Research Centre, University of Aarhus, Aarhus University Hospital, Skejby, Aarhus N, Denmark
Neuropeptides 42:331-8. 2008..Secondly, we showed that the infarct volume was reduced by alpha-MSH. The volumetric dimensions of the infarct areas measured by MRI were comparable to those measured by histology... - The α-MSH analogue AP214 attenuates rise in pulmonary pressure and fall in ejection fraction in lipopolysaccharide-induced systemic inflammatory response syndrome in pigsJens Kristensen
Department of Clinical Physiology The Institute of Clinical Medicine, Aarhus University Hospital, Skejby, Aarhus, Denmark
Clin Physiol Funct Imaging 31:54-60. 2011..SIRS is associated with considerable morbidity and mortality. Consequently, new treatment modalities are still warranted to address the different aspects of the pathophysiological process... - Distribution of sodium transporters and aquaporin-1 in the human choroid plexusJeppe Praetorius
The Water and Salt Research Center, Institute of Anatomy, Univ of Aarhus, Wilhelm Meyers Alle, Bldg 234, 8000 Aarhus C, Denmark
Am J Physiol Cell Physiol 291:C59-67. 2006..This general cross species pattern suggests central roles for these transporters in choroid plexus functions such as cerebrospinal fluid production... - Delayed onset of brain edema and mislocalization of aquaporin-4 in dystrophin-null transgenic miceZsolt Vajda
Water and Salt Research Center, University of Aarhus, DK 8000 Aarhus, Denmark
Proc Natl Acad Sci U S A 99:13131-6. 2002..Moreover, these results predict that interference with the subcellular localization of AQP4 may have therapeutic potential for delaying the onset of impending brain edema... - Direct effect of methylprednisolone on renal sodium and water transport via the principal cells in the kidneyThomas G Lauridsen
Department of Medical Research, Holstebro Hospital, University of Aarhus, Holstebro, Denmark
Eur J Endocrinol 162:961-9. 2010..We tested the hypothesis that methylprednisolone treatment increased renal water and sodium absorption by increased absorption via the aquaporin-2 (AQP2) water channels and the epithelial sodium channels (ENaCs) respectively...