Jens Mogensen

Summary

Affiliation: University of Copenhagen
Country: Denmark

Publications

  1. ncbi request reprint Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy
    Jens Mogensen
    Department of Cardiological Sciences, St George s Hospital Medical School, London, United Kingdom
    J Am Coll Cardiol 44:2033-40. 2004
  2. ncbi request reprint Frequency and clinical expression of cardiac troponin I mutations in 748 consecutive families with hypertrophic cardiomyopathy
    Jens Mogensen
    Department of Cardiological Sciences, St George s Hospital Medical School, London, United Kingdom
    J Am Coll Cardiol 44:2315-25. 2004
  3. ncbi request reprint Prevalence, clinical significance, and genetic basis of hypertrophic cardiomyopathy with restrictive phenotype
    Toru Kubo
    Department of Medicine, University College London, London, United Kingdom
    J Am Coll Cardiol 49:2419-26. 2007
  4. ncbi request reprint Novel mutation in cardiac troponin I in recessive idiopathic dilated cardiomyopathy
    Ross T Murphy
    Department of Cardiological Sciences, St George s Hospital Medical School, London, UK
    Lancet 363:371-2. 2004
  5. doi request reprint Long-term outcomes in hypertrophic cardiomyopathy caused by mutations in the cardiac troponin T gene
    Ferdinando Pasquale
    Heart Hospital, Institute of Cardiovascular Sciences, University College London, London, United Kingdom
    Circ Cardiovasc Genet 5:10-7. 2012
  6. ncbi request reprint Novel mutation in desmoplakin causes arrhythmogenic left ventricular cardiomyopathy
    Mark Norman
    Department of Cardiological Sciences, St George s Hospital Medical School, London, England
    Circulation 112:636-42. 2005
  7. pmc Idiopathic restrictive cardiomyopathy is part of the clinical expression of cardiac troponin I mutations
    Jens Mogensen
    Department of Cardiological Sciences, St George s Hospital Medical School, Tooting, London, United Kingdom
    J Clin Invest 111:209-16. 2003
  8. ncbi request reprint Adenosine monophosphate-activated protein kinase disease mimicks hypertrophic cardiomyopathy and Wolff-Parkinson-White syndrome: natural history
    Ross T Murphy
    The Heart Hospital, University College London, London, United Kingdom
    J Am Coll Cardiol 45:922-30. 2005
  9. doi request reprint Left ventricular longitudinal systolic function after alcohol septal ablation for hypertrophic obstructive cardiomyopathy: a long-term follow-up study focused on speckle tracking echocardiography
    Anders Sommer
    Department of Cardiology, Aarhus University Hospital, Skejby, Brendstrupgaardsvej 100, 8200 Aarhus N, Denmark
    Eur J Echocardiogr 11:883-8. 2010
  10. ncbi request reprint Functional effects of the DCM mutant Gly159Asp troponin C in skinned muscle fibres
    Laura C Preston
    Department of Physiology, University of Oxford, Oxford, UK
    Pflugers Arch 453:771-6. 2007

Collaborators

  • William J McKenna
  • Perry Elliott
  • Juan R Gimeno
  • James C Moon
  • Juan Pablo Kaski
  • Srijita Sen-Chowdhry
  • Calum A Macrae
  • Steve Marston
  • H Eiberg
  • Ross T Murphy
  • Petros Syrris
  • Toru Kubo
  • Ferdinando Pasquale
  • Sian Hughes
  • Anders Sommer
  • Laura C Preston
  • Paul Robinson
  • Hugh Watkins
  • Eyman Osman
  • Ajay Bahl
  • Mahmooda Mirza
  • Søren Vang
  • Mark Norman
  • Anthony Shaw
  • Peter Bross
  • Anders D Børglum
  • Niels Gregersen
  • Jens J Hansen
  • Leif Thuesen
  • Henrik Egeblad
  • Steen Hvitfeldt Poulsen
  • Chris C Ashley
  • Rajesh Thaman
  • Simon Lipscomb
  • Charles S Redwood
  • Yoshinori Doi
  • Ulla Steffensen
  • Morten Steffensen
  • Thomas J Corydon
  • Edward Rowland
  • Michael G Hanna
  • Andrew Crosby
  • Kate McGarry
  • Alison Evans
  • Janice L Holton
  • Ruth Willott
  • Charles Redwood
  • Michael Simpson
  • Judith Frydman
  • Grainne Gorman
  • Michael Farrell
  • Melissa D Scott
  • Christopher Ashley
  • Marit Nyholm Nielsen
  • Majken Westergaard
  • Lars Bolund
  • Karsten Kristiansen

Detail Information

Publications17

  1. ncbi request reprint Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy
    Jens Mogensen
    Department of Cardiological Sciences, St George s Hospital Medical School, London, United Kingdom
    J Am Coll Cardiol 44:2033-40. 2004
    ....
  2. ncbi request reprint Frequency and clinical expression of cardiac troponin I mutations in 748 consecutive families with hypertrophic cardiomyopathy
    Jens Mogensen
    Department of Cardiological Sciences, St George s Hospital Medical School, London, United Kingdom
    J Am Coll Cardiol 44:2315-25. 2004
    ..The aim of this study was to evaluate the potential utility of genetic diagnosis in clinical management of families with hypertrophic cardiomyopathy (HCM) caused by mutations in the gene for cardiac troponin I (TNNI3)...
  3. ncbi request reprint Prevalence, clinical significance, and genetic basis of hypertrophic cardiomyopathy with restrictive phenotype
    Toru Kubo
    Department of Medicine, University College London, London, United Kingdom
    J Am Coll Cardiol 49:2419-26. 2007
    ....
  4. ncbi request reprint Novel mutation in cardiac troponin I in recessive idiopathic dilated cardiomyopathy
    Ross T Murphy
    Department of Cardiological Sciences, St George s Hospital Medical School, London, UK
    Lancet 363:371-2. 2004
    ..TNNI3 is the first recessive gene identified for this condition, and we suggest that other such genes could be pinpointed by mutation analyses designed to identify homozygous mutations...
  5. doi request reprint Long-term outcomes in hypertrophic cardiomyopathy caused by mutations in the cardiac troponin T gene
    Ferdinando Pasquale
    Heart Hospital, Institute of Cardiovascular Sciences, University College London, London, United Kingdom
    Circ Cardiovasc Genet 5:10-7. 2012
    ..However, previous studies are limited by sample size, cross-sectional design, and few data in relatives...
  6. ncbi request reprint Novel mutation in desmoplakin causes arrhythmogenic left ventricular cardiomyopathy
    Mark Norman
    Department of Cardiological Sciences, St George s Hospital Medical School, London, England
    Circulation 112:636-42. 2005
    ..Primary left ventricular (LV) variants of the disease are increasingly recognized. We report on a large family with autosomal-dominant left-sided ARVC...
  7. pmc Idiopathic restrictive cardiomyopathy is part of the clinical expression of cardiac troponin I mutations
    Jens Mogensen
    Department of Cardiological Sciences, St George s Hospital Medical School, Tooting, London, United Kingdom
    J Clin Invest 111:209-16. 2003
    ..All mutations appeared in conserved and functionally important domains of the gene. This article was published online in advance of the print edition. The date of publication is available from the JCI website, http://www.jci.org...
  8. ncbi request reprint Adenosine monophosphate-activated protein kinase disease mimicks hypertrophic cardiomyopathy and Wolff-Parkinson-White syndrome: natural history
    Ross T Murphy
    The Heart Hospital, University College London, London, United Kingdom
    J Am Coll Cardiol 45:922-30. 2005
    ....
  9. doi request reprint Left ventricular longitudinal systolic function after alcohol septal ablation for hypertrophic obstructive cardiomyopathy: a long-term follow-up study focused on speckle tracking echocardiography
    Anders Sommer
    Department of Cardiology, Aarhus University Hospital, Skejby, Brendstrupgaardsvej 100, 8200 Aarhus N, Denmark
    Eur J Echocardiogr 11:883-8. 2010
    ..To examine left ventricular (LV) longitudinal systolic myocardial function in patients with hypertrophic obstructive cardiomyopathy (HOCM) before and after transcoronary ablation of septal hypertrophy (TASH)...
  10. ncbi request reprint Functional effects of the DCM mutant Gly159Asp troponin C in skinned muscle fibres
    Laura C Preston
    Department of Physiology, University of Oxford, Oxford, UK
    Pflugers Arch 453:771-6. 2007
    ..In vivo, this mutation may cause both a slowing of force generation and reduction in total systolic force. This represents a novel mechanism by which a cardiomyopathy-causing mutation can affect contractility...
  11. ncbi request reprint Dilated cardiomyopathy mutations in three thin filament regulatory proteins result in a common functional phenotype
    Mahmooda Mirza
    National Heart and Lung Institute, Imperial College London, London SW3 6LY, United Kingdom
    J Biol Chem 280:28498-506. 2005
    ....
  12. ncbi request reprint Left ventricular outflow tract obstruction and sudden death risk in patients with hypertrophic cardiomyopathy
    Perry M Elliott
    The Heart Hospital, University College London, 16 18 Westmoreland Street, London W1G 8PH, UK
    Eur Heart J 27:1933-41. 2006
    ..The influence of LVOTO on survival from SD in relation to other recognized clinical risk markers is unknown...
  13. ncbi request reprint Current approaches to unravel the mystery of dilated cardiomyopathy, a common cause of hereditary heart failure
    Jens Mogensen
    Expert Rev Proteomics 2:827-30. 2005
  14. ncbi request reprint Actin mutations in hypertrophic and dilated cardiomyopathy cause inefficient protein folding and perturbed filament formation
    Søren Vang
    Research Unit for Molecular Medicine, Aarhus University Hospital and Faculty of Health Sciences, Denmark
    FEBS J 272:2037-49. 2005
    ..We propose that effects of mutations on folding and fiber assembly may play a role in the molecular disease mechanism...
  15. ncbi request reprint Hypertrophic cardiomyopathy-the clinical challenge of managing a hereditary heart condition
    Jens Mogensen
    Eur Heart J 24:496-8. 2003
  16. ncbi request reprint Genomic structure of the human mitochondrial chaperonin genes: HSP60 and HSP10 are localised head to head on chromosome 2 separated by a bidirectional promoter
    Jens J Hansen
    Research Unit for Molecular Medicine, Faculty of Health Sciences and Arhus University Hospital, Arhus, Denmark
    Hum Genet 112:71-7. 2003
    ....
  17. ncbi request reprint Role of genotyping in risk factor assessment for sudden death in hypertrophic cardiomyopathy
    William J McKenna
    J Am Coll Cardiol 39:2049-51. 2002