A Kjaer

Summary

Affiliation: University of Copenhagen
Country: Denmark

Publications

  1. pmc Tumor volume in subcutaneous mouse xenografts measured by microCT is more accurate and reproducible than determined by 18F-FDG-microPET or external caliper
    Mette Munk Jensen
    Cluster for Molecular Imaging, University of Copenhagen, Copenhagen, Denmark
    BMC Med Imaging 8:16. 2008
  2. ncbi request reprint Combined Indium-111 octreotide scintigraphy and low-dose computed tomography in localization of neuroendocrine tumors
    Andreas Kjaer
    Department of Clinical Physiology and Nuclear Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    Clin Nucl Med 28:506-8. 2003
  3. ncbi request reprint [Leukocyte scintigraphy: indications and diagnostic value]
    A Kjaer
    H S Rigshospitalet, klinisk fysiologisk og nuklearmedicinsk klinik and epidemiklinikken
    Ugeskr Laeger 163:4380-4. 2001
  4. ncbi request reprint Dipyridamole, cold pressor test, and demonstration of endothelial dysfunction: a PET study of myocardial perfusion in diabetes
    Andreas Kjaer
    Department of Clinical Physiology and Nuclear Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    J Nucl Med 44:19-23. 2003
  5. ncbi request reprint [Neuroendocrine activation in heart insufficiency II. Can diagnosis be confirmed and prognosis evaluated by a blood test?]
    A Kjaer
    Panum Instituttet, Københavns Universitet, Medicinsk Fysiologisk Institut
    Ugeskr Laeger 162:5910-3. 2000
  6. ncbi request reprint Diagnostic value of (111)In-granulocyte scintigraphy in patients with fever of unknown origin
    Andreas Kjaer
    Department of Clinical Physiology and Nuclear Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    J Nucl Med 43:140-4. 2002
  7. ncbi request reprint Primary diagnosis of multiple pheochromocytomas in the brother of a MEN-2 patient by simultaneous MIBG scintigraphy and low-dose computed tomography
    Andreas Kjaer
    Department of Clinical Physiology and Nuclear Medicine, Rigshospitalet, Copenhagen, Denmark
    Clin Nucl Med 27:868-70. 2002
  8. ncbi request reprint [Scintigraphy combined with CT. The Danish Society of Clinical Physiology and Nuclear Medicine]
    Andreas Kjaer
    Klinisk fysiologisk og nuklearmedicinsk afdeling KF 4011, H S Rigshospitalet, DK 2100 København
    Ugeskr Laeger 164:1661. 2002
  9. doi request reprint Short-term oral treatment with the angiotensin II receptor antagonist losartan does not improve coronary vasomotor function in asymptomatic type 2 diabetes patients
    Andreas Kjaer
    Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, Copenhagen University Hospital, Denmark
    Diabetes Res Clin Pract 84:34-8. 2009
  10. ncbi request reprint [Localization diagnostics of neuroendocrine gastrointestinal tumours]
    Andreas Kjaer
    Klinik for Klinisk Fysiologi, Nuklearmedicin and PET, Rigshospitalet, 2100 København Ø, Denmark
    Ugeskr Laeger 172:2953-6. 2010

Detail Information

Publications87

  1. pmc Tumor volume in subcutaneous mouse xenografts measured by microCT is more accurate and reproducible than determined by 18F-FDG-microPET or external caliper
    Mette Munk Jensen
    Cluster for Molecular Imaging, University of Copenhagen, Copenhagen, Denmark
    BMC Med Imaging 8:16. 2008
    ..Furthermore, we evaluated the accuracy of tumor volume determined from 18F-fluorodeoxyglucose (18F-FDG) PET...
  2. ncbi request reprint Combined Indium-111 octreotide scintigraphy and low-dose computed tomography in localization of neuroendocrine tumors
    Andreas Kjaer
    Department of Clinical Physiology and Nuclear Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    Clin Nucl Med 28:506-8. 2003
  3. ncbi request reprint [Leukocyte scintigraphy: indications and diagnostic value]
    A Kjaer
    H S Rigshospitalet, klinisk fysiologisk og nuklearmedicinsk klinik and epidemiklinikken
    Ugeskr Laeger 163:4380-4. 2001
    ..Fever of unknown origin represents a diagnostic challenge. Although the sensitivity of leukocyte scintigraphy is only modest in this context, it seems to be a valuable addition to other tests performed in these patients...
  4. ncbi request reprint Dipyridamole, cold pressor test, and demonstration of endothelial dysfunction: a PET study of myocardial perfusion in diabetes
    Andreas Kjaer
    Department of Clinical Physiology and Nuclear Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    J Nucl Med 44:19-23. 2003
    ..In addition, we studied the effect of acute angiotensin-converting enzyme (ACE) inhibition on the flow response...
  5. ncbi request reprint [Neuroendocrine activation in heart insufficiency II. Can diagnosis be confirmed and prognosis evaluated by a blood test?]
    A Kjaer
    Panum Instituttet, Københavns Universitet, Medicinsk Fysiologisk Institut
    Ugeskr Laeger 162:5910-3. 2000
    ....
  6. ncbi request reprint Diagnostic value of (111)In-granulocyte scintigraphy in patients with fever of unknown origin
    Andreas Kjaer
    Department of Clinical Physiology and Nuclear Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    J Nucl Med 43:140-4. 2002
    ..Also studied was whether increased peripheral leukocyte count or C-reactive protein (CRP) level could be used to select patients for scintigraphy to raise the diagnostic value...
  7. ncbi request reprint Primary diagnosis of multiple pheochromocytomas in the brother of a MEN-2 patient by simultaneous MIBG scintigraphy and low-dose computed tomography
    Andreas Kjaer
    Department of Clinical Physiology and Nuclear Medicine, Rigshospitalet, Copenhagen, Denmark
    Clin Nucl Med 27:868-70. 2002
    ..Based on the findings of this case, the authors believe that combined MIBG scintigraphy and low-dose CT is a promising future single imaging technique for pheochromocytomas...
  8. ncbi request reprint [Scintigraphy combined with CT. The Danish Society of Clinical Physiology and Nuclear Medicine]
    Andreas Kjaer
    Klinisk fysiologisk og nuklearmedicinsk afdeling KF 4011, H S Rigshospitalet, DK 2100 København
    Ugeskr Laeger 164:1661. 2002
  9. doi request reprint Short-term oral treatment with the angiotensin II receptor antagonist losartan does not improve coronary vasomotor function in asymptomatic type 2 diabetes patients
    Andreas Kjaer
    Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, Copenhagen University Hospital, Denmark
    Diabetes Res Clin Pract 84:34-8. 2009
    ..The aim of the present study was to extend this investigation to an angiotensin II receptor blocker (ARB) administered orally in normotensive, asymptomatic type 2 diabetes patients without albuminuria...
  10. ncbi request reprint [Localization diagnostics of neuroendocrine gastrointestinal tumours]
    Andreas Kjaer
    Klinik for Klinisk Fysiologi, Nuklearmedicin and PET, Rigshospitalet, 2100 København Ø, Denmark
    Ugeskr Laeger 172:2953-6. 2010
    ..The strengths of the different modalities are discussed and it is concluded that frequently a combination of imaging modalities is necessary in the work-up of patients with neuroendocrine tumours...
  11. ncbi request reprint Right ventricular volume and mass determined by cine magnetic resonance imaging in HIV patients with possible right ventricular dysfunction
    Andreas Kjaer
    Department of Clinical Physiology, Nuclear Medicine, and PET, Rigshospitalet, Copenhagen, Denmark
    Angiology 57:341-6. 2006
    ..With use of MRI, a few patients with HIV may have a marginally reduced RVEF but normal RV dimensions and mass. Thus, RV dysfunction does not seem to constitute a major clinical problem in this antivirally treated HIV population...
  12. ncbi request reprint [Neuroendocrine activation in heart failure I. Pathophysiology and pharmacological intervention]
    A Kjaer
    Københavns Universitet, Panum Instituttet
    Ugeskr Laeger 162:5905-9. 2000
    ..It is concluded that, in addition to the known interventional principles of neuroendocrine activation, there is a series of new exciting principles and some of them might become important in the future...
  13. ncbi request reprint [Molecular imaging with positron emission tomography and single photon emission computer tomography. Status and perspectives]
    Andreas Kjaer
    H S Rigshospitalet, Klinik for Klinisk Fysiologi, Nuklearmedicin and PET, og Københavns Universitet, Det Sundhedsvidenskabelige Fakultet, Cluster for Molecular Imaging
    Ugeskr Laeger 167:4549-52. 2005
    ..This status article briefly discusses the newest applications and their importance and perspective in relation to the shift in paradigm in medicine towards more individualized treatment...
  14. ncbi request reprint Dehydration-induced renin secretion: involvement of histaminergic neurons
    A Kjaer
    Department of Medical Physiology, Panum Institute, University of Copenhagen, Denmark
    Neuroendocrinology 67:325-9. 1998
    ..The effect is probably indirect and may among others involve the catecholaminergic and serotonergic systems...
  15. ncbi request reprint Selective inhibition of magnocellular vasopressin neurons by hypoosmolality: effect on histamine- and stress-induced secretion of adrenocorticotropin and prolactin
    A Kjaer
    Department of Medical Physiology, Panum Institute, University of Copenhagen, Denmark
    Neuroendocrinology 67:330-5. 1998
    ..In summary, chronic hypoosmolality inhibits HA-induced ACTH and restraint-stress-induced PRL secretion indicating involvement of magnocellular AVP in these responses...
  16. ncbi request reprint Positron emission tomographic evaluation of regulation of myocardial perfusion in physiological (elite athletes) and pathological (systemic hypertension) left ventricular hypertrophy
    Andreas Kjaer
    Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet University Hospital, Copenhagen, Denmark
    Am J Cardiol 96:1692-8. 2005
    ..Endothelial dysfunction may contribute to the reduced perfusion reserve seen in hypertensive LVH...
  17. ncbi request reprint Right-sided cardiac function in healthy volunteers measured by first-pass radionuclide ventriculography and gated blood-pool SPECT: comparison with cine MRI
    Andreas Kjaer
    Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, Copenhagen, Denmark
    Clin Physiol Funct Imaging 25:344-9. 2005
    ..The aim of our study was to compare the agreement between these methods when measuring right-sided cardiac function...
  18. ncbi request reprint Basal and exercise-induced neuroendocrine activation in patients with heart failure and in normal subjects
    Andreas Kjaer
    Department of Clinical Physiology and Nuclear Medicine, Frederiksberg Hospital, University of Copenhagen, Frederiksberg, Denmark
    Eur J Heart Fail 6:29-39. 2004
    ..Most previous studies have looked at activation during maximal exercise, whereas we believe that activation at a submaximal level might be more pathophysiologically relevant...
  19. ncbi request reprint Fever of unknown origin: prospective comparison of diagnostic value of 18F-FDG PET and 111In-granulocyte scintigraphy
    Andreas Kjaer
    Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Eur J Nucl Med Mol Imaging 31:622-6. 2004
    ..The poorer performance of FDG-PET is in particular attributable to a high percentage of false positive scans, leading to low specificity...
  20. ncbi request reprint Dehydration-induced vasopressin secretion in humans: involvement of the histaminergic system
    A Kjaer
    Department of Medical Physiology, Division of Endocrinology and Metabolism, The Panum Institute, Rigshospitalet, University of Copenhagen, DK 2200 Copenhagen N, Denmark
    Am J Physiol Endocrinol Metab 279:E1305-10. 2000
    ..In addition, the regulation of aldosterone secretion during dehydration also seems to involve the histaminergic system via H(1) and H(2) receptors...
  21. ncbi request reprint Attenuation and scatter correction in myocardial SPET: improved diagnostic accuracy in patients with suspected coronary artery disease
    Andreas Kjaer
    Department of Clinical Physiology and Nuclear Medicine, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, Denmark
    Eur J Nucl Med Mol Imaging 29:1438-42. 2002
    ..In conclusion, we found a commercial system for AC and SC in myocardial SPET to be of great diagnostic help in a consecutive series of patients. Using CAG as a reference, the SCAC interpretation was confirmed in nearly all cases...
  22. ncbi request reprint Stress-induced release of anterior pituitary hormones: effect of H3 receptor-mediated inhibition of histaminergic activity or posterior hypothalamic lesion
    U Knigge
    Department of Medical Physiology, University of Copenhagen, Denmark
    Neuroendocrinology 69:44-53. 1999
    ..Furthermore, in accordance with our previous findings, the lesion experiments indicated the existence of an interaction between the histaminergic and serotonergic system in regulation of the stress- and LPS-induced PRL release...
  23. ncbi request reprint Histaminergic and catecholaminergic interactions in the central regulation of vasopressin and oxytocin secretion
    U Knigge
    Department of Medical Physiology, The Panum Institute, Copenhagen N, Denmark
    Endocrinology 140:3713-9. 1999
    ..The present findings further substantiate the role of histaminergic neurons in the central regulation of neurohypophysial hormone secretion...
  24. ncbi request reprint Histamine and prostaglandin interaction in regulation of oxytocin and vasopressin secretion
    U Knigge
    Department of Medical Physiology, Division of Endocrinology and Metabolism, The Panum Institute, University of Copenhagen, Denmark
    J Neuroendocrinol 15:940-5. 2003
    ..Furthermore, histamine as well as LPS may affect oxytocin and vasopressin neurones via activation of prostaglandins, probably in the hypothalamic supraoptic nucleus...
  25. ncbi request reprint Serotonin stimulates hypothalamic mRNA expression and local release of neurohypophysial peptides
    H Jørgensen
    Department of Medical Physiology, The Panum Institute 12 3 21, Rigshospitalet, University of Copenhagen, Blegdamsvej 3, DK 2200N Copenhagen, Denmark
    J Neuroendocrinol 15:564-71. 2003
    ..Corticotropin-releasing hormone appears to be partly involved in the mediation of 5-HT induced vasopressin and oxytocin secretion...
  26. ncbi request reprint Evaluation of impaired left ventricular ejection fraction and increased dimensions by multiple neurohumoral plasma concentrations
    B A Groenning
    Danish Research Centre of Magnetic Resonance, Section 340, H S Hvidovre Hospital, University of Copenhagen, Kettegaard Alle 30, DK 2650, Hvidovre, Denmark
    Eur J Heart Fail 3:699-708. 2001
    ..It is, however, undetermined which marker has the greatest diagnostic potential, and whether additional information is gained by a comprehensive neurohumoral evaluation...
  27. ncbi request reprint Serotonergic involvement in stress-induced ACTH release
    H Jørgensen
    Department of Medical Physiology, The Panum Institute 12 3, University of Copenhagen, Blegdamsvej 3, DK 2200, Copenhagen N, Denmark
    Brain Res 811:10-20. 1998
    ....
  28. ncbi request reprint Histaminergic neurons are involved in the orexigenic effect of orexin-A
    E A Jørgensen
    Department of Medical Physiology, Panum Institute, University of Copenhagen, DK 2200 Copenhagen N, Denmark
    Neuroendocrinology 82:70-7. 2005
    ..We conclude that the orexigenic effect of orexin-A is dependent on an intact histaminergic neuronal system and seems to involve an H(1)-receptor mechanism...
  29. doi request reprint Reduction in circulating markers of endothelial dysfunction in HIV-infected patients during antiretroviral therapy
    U S Kristoffersen
    Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, Copenhagen, Denmark
    HIV Med 10:79-87. 2009
    ..Circulating markers of endothelial dysfunction may be used to study early atherogenesis. The aim of our study was to investigate changes in such markers during initiation of ART...
  30. ncbi request reprint Differential effect of serotonin 5-HT(1A) receptor antagonists on the secretion of corticotropin and prolactin
    H Jørgensen
    Department of Medical Physiology, Rigshospitalet, University of Copenhagen, Denmark
    Neuroendocrinology 73:322-33. 2001
    ....
  31. ncbi request reprint Serotonin receptors involved in vasopressin and oxytocin secretion
    H Jørgensen
    Department of Medical Physiology, The Panum Institute, University of Copenhagen, Copenhagen, Denmark
    J Neuroendocrinol 15:242-9. 2003
    ..5-HT-induced oxytocin secretion involves 5-HT(1A), 5-HT(2C) and 5-HT(4) receptors; in addition an involvement of 5-HT(1B), 5-HT(5A) and 5-HT(7) receptors seems likely, whereas 5-HT(2A) and 5-HT(3) receptors seem to be less important...
  32. doi request reprint Right and left cardiac function in HIV-infected patients investigated using radionuclide ventriculography and brain natriuretic peptide: a 5-year follow-up study
    U S Kristoffersen
    Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, Copenhagen, Denmark
    HIV Med 9:180-6. 2008
    ..The aim of the study was to determine the incidence of myocardial dysfunction in an HIV-infected population receiving state-of-the-art treatment...
  33. ncbi request reprint Effect of interleukin 1beta on the HPA axis in H1-receptor knockout mice
    C L Toftegaard
    Department of Medical Physiology, Panum Institute, University of Copenhagen, Copenhagen, Denmark
    Neuroimmunomodulation 10:344-50. 2002
    ..To further elucidate the role of neuronal HA in cytokine-induced activation of the HPA axis, we compared the effect of H(1)R knockout on IL-1beta-induced ACTH secretion in adult male mice...
  34. ncbi request reprint Heart failure and neuroendocrine activation: diagnostic, prognostic and therapeutic perspectives
    A Kjaer
    Department of Clinical Physiology and Nuclear Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    Clin Physiol 21:661-72. 2001
    ..In addition to beta-blockers, ACE-inhibitors and angiotensin II antagonists several new drugs based on neuroendocrine modification are on their way and might become important in the future...
  35. ncbi request reprint Changes in biomarkers of cardiovascular risk after a switch to abacavir in HIV-1-infected individuals receiving combination antiretroviral therapy
    U S Kristoffersen
    Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, Copenhagen, Denmark
    HIV Med 10:627-33. 2009
    ..To investigate, using a longitudinal design, whether biomarkers of cardiovascular risk change after a switch to an abacavir (ABC)-containing regimen in HIV-1-infected individuals already receiving combination antiretroviral therapy (ART)...
  36. doi request reprint Molecular pathology in vulnerable carotid plaques: correlation with [18]-fluorodeoxyglucose positron emission tomography (FDG-PET)
    M Graebe
    Department of Vascular Surgery, Rigshospitalet RK 3111, University of Copenhagen, Copenhagen E, Denmark
    Eur J Vasc Endovasc Surg 37:714-21. 2009
    ..Uptake was correlated to quantitative gene expression of known markers of inflammation and plaque vulnerability...
  37. ncbi request reprint Adrenocorticotropic hormone secretion in rats induced by stimulation with serotonergic compounds. hsj@mfi.ku.dk
    H Jørgensen
    Department of Medical Physiology, The Panum Institute, University of Copenhagen, Denmark
    J Neuroendocrinol 11:283-90. 1999
    ..Furthermore, an involvement of the 5-HT5A and the 5-HT7 receptor is possible...
  38. ncbi request reprint The role of hypothalamic histamine in leptin-induced suppression of short-term food intake in fasted rats
    C L Toftegaard
    Department of Medical Physiology, The Panum Institute Building 12 3, University of Copenhagen, Blegdamsvej 3, Copenhagen N, 2200, Denmark
    Regul Pept 111:83-90. 2003
    ..Therefore, we studied the possible role of HA in short-term leptin-induced suppression of food intake...
  39. ncbi request reprint Histamine- and stress-induced prolactin secretion: importance of vasopressin V1- and V2-receptors
    A Kjaer
    Department of Medical Physiology, Panum Institute, University of Copenhagen, Denmark
    Eur J Endocrinol 131:391-7. 1994
    ..We conclude that AVP seems to play a role in the mediation of HA- and restraint stress-induced secretion of PRL, and that the AVP receptor involved is primarily of the V1-type or similar to this...
  40. ncbi request reprint Effect of eight weeks of endurance exercise training on right and left ventricular volume and mass in untrained obese subjects: a longitudinal MRI study
    T W Vogelsang
    Cluster for Molecular Imaging, Department of Biomedicine, The Panum Institute, University of Copenhagen, Copenhagen, Denmark
    Scand J Med Sci Sports 18:354-9. 2008
    ..Furthermore, left VM and right VM increased. We conclude that using MRI and a longitudinal design it was possible to demonstrate similar and balanced changes in the right and left ventricle in response to training...
  41. ncbi request reprint Recent advances in nuclear cardiology
    H Gutte
    Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    Panminerva Med 50:105-18. 2008
    ....
  42. ncbi request reprint Multidetector computed tomography and neuroendocrine pancreaticoduodenal tumors
    E D Rappeport
    Department of Radiology, Rigshospitalet, State University Hospital of Copenhagen, Denmark
    Acta Radiol 47:248-56. 2006
    ..To investigate the accuracy of dedicated pancreatic multidetector computed tomography (MDCT) in the diagnosis of neuroendocrine pancreaticoduodenal tumors (NPTs)...
  43. ncbi request reprint Radiation exposure to surgical staff during F-18-FDG-guided cancer surgery
    P A Andersen
    Department of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital, 3992 Rigshospitalet, Copenhagen, Denmark
    Eur J Nucl Med Mol Imaging 35:624-9. 2008
    ..We therefore wanted to measure the absorbed staff doses at operations where patients had received a preoperative injection of (18)F-FDG...
  44. ncbi request reprint Labelling of human mesenchymal stem cells with indium-111 for SPECT imaging: effect on cell proliferation and differentiation
    L Bindslev
    Stem Cell Laboratory 9312, The Heart Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    Eur J Nucl Med Mol Imaging 33:1171-7. 2006
    ..Therefore, the aim of this study was to evaluate the influence of 111In labelling in doses relevant for SPECT imaging in humans on the viability and differentiation capacity of human MSCs...
  45. ncbi request reprint Serotonergic stimulation of corticotropin-releasing hormone and pro-opiomelanocortin gene expression
    H Jørgensen
    Department of Medical Physiology, The Panum Institute, University of Copenhagen, Denmark
    J Neuroendocrinol 14:788-95. 2002
    ..Furthermore, the results indicate that CRH is an important mediator of the ACTH response to 5-HT...
  46. doi request reprint EANM/ESC guidelines for radionuclide imaging of cardiac function
    B Hesse
    Department of Clinical Physiology and Nuclear Medicine, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark
    Eur J Nucl Med Mol Imaging 35:851-85. 2008
    ..The guidelines are designed to assist in the practice of referral to, performance, interpretation and reporting of nuclear cardiology studies for the evaluation of cardiac performance...
  47. ncbi request reprint The plasma atrial natriuretic peptide response to arm and leg exercise in humans: effect of posture
    T W Vogelsang
    The Copenhagen Muscle Research Centre, Department of Anaesthesia, Rigshospitalet, Blegdamsvej 9, Copenhagen Ø, 2100 Denmark
    Exp Physiol 91:765-71. 2006
    ..The results suggest that the similar blood pressure response to A and to A + L may relate to the enhanced central blood volume following the addition of leg to arm exercise...
  48. doi request reprint Exercise training favors increased insulin-stimulated glucose uptake in skeletal muscle in contrast to adipose tissue: a randomized study using FDG PET imaging
    M H Reichkendler
    Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark
    Am J Physiol Endocrinol Metab 305:E496-506. 2013
    ..In conclusion, aerobic exercise training increases insulin-stimulated glucose uptake in skeletal muscle but not in adipose tissue, which demonstrates some interregional differences...
  49. pmc Reversible renal impairment induced by treatment with the angiotensin II receptor antagonist candesartan in a patient with bilateral renal artery stenosis
    T L Johansen
    Department of Clinical Physiology and Nuclear Medicine, Frederiksberg Hospital, Copenhagen University Hospital, Nordre Fasanvej 57, DK 2000 Frederiksberg, Denmark
    BMC Nephrol 2:1. 2001
    ..In recent years it has also been recommended that caution should be demonstrated when angiotensin II blockers are used in the same type of patients but the evidence is based only on few cases...
  50. ncbi request reprint EANM/ESC procedural guidelines for myocardial perfusion imaging in nuclear cardiology
    B Hesse
    Department of Clinical Physiology and Nuclear Medicine, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
    Eur J Nucl Med Mol Imaging 32:855-97. 2005
    ..The guidelines do not discuss clinical indications, benefits or drawbacks of radionuclide myocardial imaging compared to non-nuclear techniques, nor do they cover cost benefit or cost effectiveness...
  51. pmc Immunolymphoscintigraphy for metastatic sentinel nodes: test of a model
    A H Chakera
    Clinic of Plastic Surgery, Breast Surgery and Burns Unit, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Int J Mol Imaging 2011:828151. 2011
    ..Results and Conclusion. Our paper suggests the theoretical possibility of a model of dual isotope immuno-lymphoscintigraphy for noninvasive, preoperative, malignant sentinel node imaging...
  52. doi request reprint Uphill running improves rat Achilles tendon tissue mechanical properties and alters gene expression without inducing pathological changes
    K M Heinemeier
    Institute of Sports Medicine, Department of Orthopedic Surgery M81, Bispebjerg Hospital and Centre of Healthy Ageing, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
    J Appl Physiol (1985) 113:827-36. 2012
    ..Improved mechanical properties were observed, as well as changes in gene-expression that were distinctly different from what is seen in tendinopathy and in response to short-term tendon loading...
  53. ncbi request reprint Lipid metabolism and coagulation during the normal menstrual cycle
    A M Lebech
    Department of Gynecology and Obstetrics, Frederiksberg Hospital, Copenhagen, Denmark
    Horm Metab Res 21:445-8. 1989
    ..g. as controls in a study of lipid metabolism in women taking sex-hormones. For coagulation studies the cycle days may, however, be of importance...
  54. ncbi request reprint Independent effects of both right and left ventricular function on plasma brain natriuretic peptide
    Thomas Wiis Vogelsang
    Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, Copenhagen, Denmark
    Eur J Heart Fail 9:892-6. 2007
    ..Brain natriuretic peptide (BNP) is increased in heart failure; however, the relative contribution of the right and left ventricles is largely unknown...
  55. ncbi request reprint Right and left ventricular cardiac function in a developed world population with human immunodeficiency virus studied with radionuclide ventriculography
    Anne Mette Lebech
    Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
    Am Heart J 147:482-8. 2004
    ..The aim of the study was to establish the prevalence of right- and left-sided cardiac dysfunction in a Danish HIV population, most of whom were undergoing HAART, with radionuclide ventriculography...
  56. ncbi request reprint [Myocardial scintigraphy in Denmark 1997-2001. Activity and status]
    Claus Leth Petersen
    Klinisk Fysiologisk Nuklearmedicinsk Afdeling, H S Frederiksberg Hospital, Nordre Fasanvej 57, DK 2000 Frederiksberg
    Ugeskr Laeger 165:2202-4. 2003
  57. doi request reprint Quantitative gene expression of somatostatin receptors and noradrenaline transporter underlying scintigraphic results in patients with neuroendocrine tumors
    Tina Binderup
    Cluster for Molecular Imaging, Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark
    Neuroendocrinology 87:223-32. 2008
    ....
  58. ncbi request reprint Myocardial perfusion imaging in Denmark: activity from 1997 to 2001 and current practice
    Claus Leth Petersen
    Department of Clinical Physiology and Nuclear Medicine, Frederiksberg Hospital H S, University of Copenhagen, Denmark
    Eur J Nucl Med Mol Imaging 30:137-40. 2003
    ..In general, the restricted camera time and the limited number of trained personnel explain the excessive waiting lists in Denmark...
  59. ncbi request reprint [Endoscopic ultrasonography in patients with suspected neuroendocrine tumors]
    Ulrich Knigge
    Ugeskr Laeger 170:2469; author reply 2471. 2008
  60. ncbi request reprint Serotonergic involvement in stress-induced vasopressin and oxytocin secretion
    Henrik Jørgensen
    Department of Medical Physiology, The Panum Institute, Rigshospitalet, University of Copenhagen, Blegdamsvej 3, DK 2200N Copenhagen, Denmark
    Eur J Endocrinol 147:815-24. 2002
    ..To investigate the involvement of serotonin (5-hydroxytryptamine - 5-HT) receptors in mediation of stress-induced arginine vasopressin (AVP) and oxytocin (OT) secretion in male rats...
  61. ncbi request reprint Neurohumoral prediction of left-ventricular morphologic response to beta-blockade with metoprolol in chronic left-ventricular systolic heart failure
    Bjoern A Groenning
    Department of Cardiology and Endocrinology, Copenhagen University Hospital Frederiksberg, Frederiksberg, Denmark
    Eur J Heart Fail 4:635-46. 2002
    ..In order to tailor therapy in heart failure, a solution might be to develop sensitive and reliable markers that can predict response in individual patients or monitor effectiveness of therapy...
  62. ncbi request reprint I-123 MIBG imaging and intraoperative localization of metastatic pheochromocytoma: a case report
    Thora Buhl
    Department of Clinical Physiology and Nuclear Medicine, Center for Medical Imaging, Informatics and Engineering in Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    Clin Nucl Med 27:183-5. 2002
    ..Preoperative I-123 MIBG scintigraphy, combined with intraoperative gamma probe identification of I-123 MIBG foci, is feasible and a valuable tool to detect malignant masses possibly overlooked by other imaging techniques...
  63. ncbi request reprint The relationship between N-terminal pro-brain natriuretic peptide and risk for hospitalization and mortality is curvilinear in patients with chronic heart failure
    Morten Schou
    Department of Cardiology and Endocrinology, Clinic E, Frederiksberg University Hospital, Frederiksberg, Denmark
    Am Heart J 154:123-9. 2007
    ..We therefore evaluated NT-proBNP as a risk marker for mortality and hospitalization and developed a simple algorithm for risk stratification based on NT-proBNP as a continuous variable...
  64. ncbi request reprint Daily consumption for six weeks of a lignan complex isolated from flaxseed does not affect endothelial function in healthy postmenopausal women
    Jesper Hallund
    Department of Clinical Physiology and Nuclear Medicine, Frederiksberg University Hospital, Frederiksberg, Denmark
    J Nutr 136:2314-8. 2006
    ..72). Plasma concentrations of NOx, ET-1, and ADMA were not affected. We conclude that daily consumption for 6 wk of a low-fat muffin enriched with a lignan complex had no effect on endothelial function in healthy postmenopausal women...
  65. ncbi request reprint Unexplained week-to-week variation in BNP and NT-proBNP is low in chronic heart failure patients during steady state
    Morten Schou
    Department of Cardiology and Endocrinology, Clinic E, Frederiksberg University Hospital, Ndr Fasanvej 57 59, DK 2000 Frederiksberg, Denmark
    Eur J Heart Fail 9:68-74. 2007
    ..The usefulness of brain-natriuretic-peptide (BNP) and N-terminal-pro-brain-natriuretic-peptide (NT-proBNP) for monitoring of chronic heart failure (CHF) patients has been questioned because of high levels of unexplained variation...
  66. ncbi request reprint The effect of dynamic knee-extension exercise on patellar tendon and quadriceps femoris muscle glucose uptake in humans studied by positron emission tomography
    Kari K Kalliokoski
    Copenhagen Muscle Research Centre, Institute of Sports Medicine, Bispebjerg Hospital, Denmark
    J Appl Physiol (1985) 99:1189-92. 2005
    ..Thus tendon glucose uptake is likely to be regulated by mechanisms independently of those regulating skeletal muscle glucose uptake...
  67. ncbi request reprint Self-reported fatigue common among optimally treated HIV patients: no correlation with cerebral FDG-PET scanning abnormalities
    Ase B Andersen
    Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    Neuroimmunomodulation 13:69-75. 2006
    ....
  68. ncbi request reprint Bone infection in patients suspected of complicating osteomyelitis: the diagnostic value of dual isotope bone-granulocyte scintigraphy
    Thora Buhl
    Department of Clinical Physiology and Nuclear Medicine, University Hospital, Copenhagen, Denmark
    Clin Physiol Funct Imaging 25:20-6. 2005
    ..e. complicating osteomyelitis, using per-operative bacterial culture from bone as reference...
  69. ncbi request reprint Automated interpretation of PET/CT images in patients with lung cancer
    Henrik Gutte
    Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, Copenhagen University Hospital, Denmark
    Nucl Med Commun 28:79-84. 2007
    ....
  70. ncbi request reprint Impact of medical treatment on lung diffusion capacity in elderly patients with heart failure. Baseline characteristics and 1-year follow up after medical treatment
    Claus Leth Petersen
    Department of Clinical Physiology and Nuclear Medicine, H S Frederiksberg Hospital, University of Copenhagen, Ndr Fasanvej 57, 2000 F, Copenhagen, Denmark
    Int J Cardiol 98:453-7. 2005
    ....
  71. ncbi request reprint Natriuretic peptides in the monitoring of anthracycline induced reduction in left ventricular ejection fraction
    Gedske Daugaard
    Department of Clinical Physiology and Nuclear Medicine, Rigshospitalet, Copenhagen Ø, Denmark
    Eur J Heart Fail 7:87-93. 2005
    ..The use of anthracyclines in treatment of cancer is limited by cardiotoxicity of these compounds and may lead to heart failure. Therefore monitoring of cardiac function is necessary during therapy...
  72. ncbi request reprint Neurohormones as markers of right- and left-sided cardiac dimensions and function in patients with untreated chronic heart failure
    Andreas Kjaer
    Department of Clinical Physiology and Nuclear Medicine, Frederiksberg Hospital, University of Copenhagen, Denmark
    Int J Cardiol 99:301-6. 2005
    ..In order to study this, we investigated the relationship between hormones and cardiac dimensions and function of both the right and left ventricle...
  73. ncbi request reprint Evaluation of right ventricular volume and function by 2D and 3D echocardiography compared to MRI
    Jesper Kjaergaard
    Department of Cardiology, Copenhagen University Hospital, Gentofte, Denmark
    Eur J Echocardiogr 7:430-8. 2006
    ....
  74. ncbi request reprint [Magnetic resonance imaging of the heart. Danish Society of Clinical Physiology and Nuclear Medicine]
    Claus Leth Petersen
    Klinisk Fysiologisk Nuklearmedicinsk Afdeling, H S Frederiksberg Hospital, Nordre Fasanvej 57 59, 2000 Frederiksberg
    Ugeskr Laeger 167:1386. 2005
  75. ncbi request reprint Advanced quantitative echocardiography in arrhythmogenic right ventricular cardiomyopathy
    Jesper Kjaergaard
    Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
    J Am Soc Echocardiogr 20:27-35. 2007
    ..Three-dimensional echocardiography and Doppler tissue imaging (DTI) are new echocardiographic modalities for the evaluation of global and regional function, but the diagnostic potential remains to be assessed...
  76. ncbi request reprint Early clinical experience and impact of 18F-FDG PET
    Henrik Gutte
    Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet Copenhagen, Denmark
    Nucl Med Commun 26:989-94. 2005
    ..To determine the influence and impact of [F]- fluorodeoxyglucose positron emission tomography (FDG PET) in Denmark...
  77. ncbi request reprint BNP cannot replace gated equilibrium radionuclide ventriculography in monitoring of anthracycline-induced cardiotoxity
    Thomas W Vogelsang
    Cluster for Molecular Imaging, Department of Medical Physiology, University of Copenhagen, Denmark
    Int J Cardiol 124:193-7. 2008
    ..We hypothesized that BNP measurements could replace, at least in part, the RNV examinations. Therefore, we studied whether BNP could be used, alone or in combination with RNV, in the monitoring of anthracycline-induced cardiotoxity...
  78. ncbi request reprint Utility of planar bone scintigraphy to distinguish benign osteochondromas from malignant chondrosarcomas
    Helle W Hendel
    Department of Nuclear Medicine, Rigshospitalet, University of Copenhagen, Denmark
    Clin Nucl Med 27:622-4. 2002
    ..The current study was designed to evaluate the role of planar bone scintigraphy in the diagnosis of sarcomatous change in osteochondromas (cartilaginous exostoses)...
  79. ncbi request reprint Carotid intima-media thickness in HIV patients treated with antiretroviral therapy
    Anne Mette Lebech
    Department of Infectious Diseases, Hvidovre University Hospital, Hvidovre, Denmark
    Clin Physiol Funct Imaging 27:173-9. 2007
    ....
  80. ncbi request reprint Molecular imaging of cancer using PET and SPECT
    Andreas Kjaer
    Department of Clinical Physiology, Nuclear Medicine and PET Rigshospitalet and Cluster for molecular imaging, Faculty of Health Sciences, University of Copenhagen, Denmark
    Adv Exp Med Biol 587:277-84. 2006
    ..This article will briefly discuss the newest applications and their importance and perspective in relation to the shift in paradigm in medicine towards more individualized treatment...
  81. ncbi request reprint Prognostic usefulness of anemia and N-terminal pro-brain natriuretic peptide in outpatients with systolic heart failure
    Morten Schou
    Department of Cardiology and Endocrinology, Frederiksberg University Hospital, Frederiksberg, Denmark
    Am J Cardiol 100:1571-6. 2007
    ..Patients with anemia and high levels of NT-pro-BNP have a markedly increased mortality risk...
  82. ncbi request reprint Catecholaminergic activation in acute myocardial infarction: time course and relation to left ventricular performance
    Claus Leth Petersen
    Department of Clinical Physiology and Nuclear Medicine, Glostrup Hospital, University of Copenhagen, Copenhagen, Denmark
    Cardiology 100:23-8. 2003
    ....
  83. ncbi request reprint Autonomic dysfunction in HIV patients on antiretroviral therapy: studies of heart rate variability
    Anne Mette Lebech
    Department of Infectious Diseases, Hvidovre University Hospital, Copenhagen, Denmark
    Clin Physiol Funct Imaging 27:363-7. 2007
    ..At present it is not known whether introduction of ART also has decreased autonomic dysfunction...
  84. ncbi request reprint Effects of body mass index and age on N-terminal pro brain natriuretic peptide are associated with glomerular filtration rate in chronic heart failure patients
    Morten Schou
    Department of Cardiology and Endocrinology, Clinic E, Frederiksberg University Hospital, Frederiksberg, Denmark
    Clin Chem 53:1928-35. 2007
    ..We hypothesized that the effects of BMI and age on plasma concentrations of NT-proBNP are associated with GFR...
  85. ncbi request reprint Histamine and the regulation of body weight
    Emilie A Jørgensen
    Cluster for Molecular Imaging, University of Copenhagen, Copenhagen, Denmark
    Neuroendocrinology 86:210-4. 2007
    ..At present, H(3) receptor antagonists that stimulate the histaminergic system may be the most promising histaminergic drugs for antiobesity therapy...
  86. ncbi request reprint Long-term clinical variation of NT-proBNP in stable chronic heart failure patients
    Morten Schou
    Department of Cardiology and Endocrinology, Clinic E, Frederiksberg University Hospital, Ndr Fasanvej 57 59, DK 2000 Frederiksberg, Denmark
    Eur Heart J 28:177-82. 2007
    ..The proposed use of NT-proBNP for monitoring of CHF patients will require accurate information about long-term CV of the peptide...
  87. ncbi request reprint ANP and BNP in atrial fibrillation before and after cardioversion--and their relationship to cardiac volume and function
    Susette Krohn Therkelsen
    Int J Cardiol 127:396-9. 2008
    ..Changes in left atrial volume were predictive of changes in ANP and BNP following cardioversion. AF may cause enduringly elevated ANP and BNP and atrial volume seems to be an important determinant of ANP and BNP in AF...