N W Jacobsen

Summary

Affiliation: University of Copenhagen
Country: Denmark

Publications

  1. ncbi Inhibition of human aromatase complex (CYP19) by antiepileptic drugs
    N W Jacobsen
    Section of Toxicology and Environmental Chemistry, Department of Pharmaceutics and Analytical Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, DK 2100 Copenhagen Ø, Denmark
    Toxicol In Vitro 22:146-53. 2008
  2. doi Suggesting a testing strategy for possible endocrine effects of drug metabolites
    N W Jacobsen
    Department of Pharmaceutics and Analytical Chemistry, Section of Toxicology, Faculty of Pharmaceutical Sciences, University of Copenhagen, DK 2100 Copenhagen Ø, Denmark
    Regul Toxicol Pharmacol 62:441-8. 2012

Detail Information

Publications2

  1. ncbi Inhibition of human aromatase complex (CYP19) by antiepileptic drugs
    N W Jacobsen
    Section of Toxicology and Environmental Chemistry, Department of Pharmaceutics and Analytical Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, DK 2100 Copenhagen Ø, Denmark
    Toxicol In Vitro 22:146-53. 2008
    ..When adding carbamazepine to a range of valproate concentrations no additional inhibition was seen. The data for some of the AEDs show that side effects on steroid synthesis in humans due to inhibition of aromatase should be considered...
  2. doi Suggesting a testing strategy for possible endocrine effects of drug metabolites
    N W Jacobsen
    Department of Pharmaceutics and Analytical Chemistry, Section of Toxicology, Faculty of Pharmaceutical Sciences, University of Copenhagen, DK 2100 Copenhagen Ø, Denmark
    Regul Toxicol Pharmacol 62:441-8. 2012
    ..Subsequently, a five step integrated strategy for screening of the potential endocrine effects of drugs and their metabolites are proposed...