Anne Mette Hvas

Summary

Affiliation: University of Copenhagen
Country: Denmark

Publications

  1. doi request reprint Ex-vivo response to blood products and haemostatic agents after paediatric cardiac surgery
    Anne Mette Hvas
    Department of Clinical Biochemistry, Centre for Haemophilia and Thrombosis, Aarhus University Hospital, Brendstrupgaardsvej 100, Aarhus, Denmark
    Blood Coagul Fibrinolysis 24:587-92. 2013
  2. doi request reprint Reduced antiplatelet effect of aspirin is associated with low-grade inflammation in patients with coronary artery disease
    S B Larsen
    Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Brendstrupgaardsvej 100, Aarhus N, Denmark
    Thromb Haemost 109:920-9. 2013
  3. doi request reprint Change in hemostatic intervention after implementation of thromboelastometry
    Anne Mette Hvas
    Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Denmark
    J Cardiothorac Vasc Anesth 26:227-31. 2012
  4. ncbi request reprint Vitamin B12 treatment normalizes metabolic markers but has limited clinical effect: a randomized placebo-controlled study
    A M Hvas
    Department of Hematology, Aas, Aarhus University Hospital, Tage Hansens Gade 2, 8000 Aarhus C, Denmark
    Clin Chem 47:1396-404. 2001
  5. ncbi request reprint Circadian variation of holo-transcobalamin (holo-TC) and related markers
    Anne Mette Hvas
    Department of Clinical Biochemistry, SKS, Aarhus University Hospital, Aarhus, Denmark
    Clin Chem Lab Med 43:760-4. 2005
  6. ncbi request reprint Vitamin B12 and vitamin B6 supplementation is needed among adults with phenylketonuria (PKU)
    A M Hvas
    Department of Clinical Biochemistry, SKS, Aarhus University Hospital, Aarhus, Denmark
    J Inherit Metab Dis 29:47-53. 2006
  7. ncbi request reprint The effect of recombinant human intrinsic factor on the uptake of vitamin B12 in patients with evident vitamin B12 deficiency
    Anne Mette Hvas
    Department of Clinical Biochemistry, Skejby Hospital and Aarhus Hospital, Aarhus University Hospital, Aarhus, Denmark
    Haematologica 91:805-8. 2006
  8. ncbi request reprint Diagnosis and treatment of vitamin B12 deficiency--an update
    Anne Mette Hvas
    Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Denmark
    Haematologica 91:1506-12. 2006
  9. ncbi request reprint Tranexamic acid combined with recombinant factor VIII increases clot resistance to accelerated fibrinolysis in severe hemophilia A
    A M Hvas
    Center for Hemophilia and Thrombosis, Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Brendstrupgaardsvej 100, Aarhus N, Denmark
    J Thromb Haemost 5:2408-14. 2007
  10. doi request reprint Thrombophilia risk factors are associated with intrauterine foetal death and pregnancy-related venous thromboembolism
    Anne Mette Hvas
    Center for Haemophilia and Thrombosis, Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Denmark
    Scand J Clin Lab Invest 69:288-94. 2009

Collaborators

Detail Information

Publications55

  1. doi request reprint Ex-vivo response to blood products and haemostatic agents after paediatric cardiac surgery
    Anne Mette Hvas
    Department of Clinical Biochemistry, Centre for Haemophilia and Thrombosis, Aarhus University Hospital, Brendstrupgaardsvej 100, Aarhus, Denmark
    Blood Coagul Fibrinolysis 24:587-92. 2013
    ..Ex-vivo studies showed a total reversal of the coagulopathy after addition of pooled platelets and significantly improved clot stability after addition of fibrinogen concentrate, FFP and tranexamic acid, respectively...
  2. doi request reprint Reduced antiplatelet effect of aspirin is associated with low-grade inflammation in patients with coronary artery disease
    S B Larsen
    Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Brendstrupgaardsvej 100, Aarhus N, Denmark
    Thromb Haemost 109:920-9. 2013
    ..These findings may suggest that chronic low-grade inflammation reduce the antiplatelet effect of aspirin...
  3. doi request reprint Change in hemostatic intervention after implementation of thromboelastometry
    Anne Mette Hvas
    Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Denmark
    J Cardiothorac Vasc Anesth 26:227-31. 2012
    ..To monitor the use of blood products and hemostatic intervention after implementation of thromboelastometry...
  4. ncbi request reprint Vitamin B12 treatment normalizes metabolic markers but has limited clinical effect: a randomized placebo-controlled study
    A M Hvas
    Department of Hematology, Aas, Aarhus University Hospital, Tage Hansens Gade 2, 8000 Aarhus C, Denmark
    Clin Chem 47:1396-404. 2001
    ..The clinical significance of increased plasma methylmalonic acid (P-MMA) is unclear. We assessed the efficacy of vitamin B12 treatment in reducing P-MMA and plasma total homocysteine compared with the clinical benefits of treatment...
  5. ncbi request reprint Circadian variation of holo-transcobalamin (holo-TC) and related markers
    Anne Mette Hvas
    Department of Clinical Biochemistry, SKS, Aarhus University Hospital, Aarhus, Denmark
    Clin Chem Lab Med 43:760-4. 2005
    ..This supports the view that holo-TC is a marker of long-term vitamin B(12) status, and that samples may also be obtained from non-fasting subjects...
  6. ncbi request reprint Vitamin B12 and vitamin B6 supplementation is needed among adults with phenylketonuria (PKU)
    A M Hvas
    Department of Clinical Biochemistry, SKS, Aarhus University Hospital, Aarhus, Denmark
    J Inherit Metab Dis 29:47-53. 2006
    ..In conclusion PKU patients need continuing dietary guidance throughout adult life, and considering the risks, costs and potential benefits, daily vitamin supplementation seems justified in these patients...
  7. ncbi request reprint The effect of recombinant human intrinsic factor on the uptake of vitamin B12 in patients with evident vitamin B12 deficiency
    Anne Mette Hvas
    Department of Clinical Biochemistry, Skejby Hospital and Aarhus Hospital, Aarhus University Hospital, Aarhus, Denmark
    Haematologica 91:805-8. 2006
    ..Twenty-eight patients with suspected vitamin B12 deficiency showed no additional increase in holoTC after intake of rhIF-B12. We conclude that rhIF promotes B12 absorption among patients with evident vitamin B12 deficiency...
  8. ncbi request reprint Diagnosis and treatment of vitamin B12 deficiency--an update
    Anne Mette Hvas
    Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Denmark
    Haematologica 91:1506-12. 2006
    ..Once the diagnosis of vitamin B12 deficiency has been confirmed efficient treatment can be ensured either by injections every 2-3 month or by a daily dose of 1 mg vitamin B12...
  9. ncbi request reprint Tranexamic acid combined with recombinant factor VIII increases clot resistance to accelerated fibrinolysis in severe hemophilia A
    A M Hvas
    Center for Hemophilia and Thrombosis, Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Brendstrupgaardsvej 100, Aarhus N, Denmark
    J Thromb Haemost 5:2408-14. 2007
    ..In addition to both the delayed and slow development of a clot, previous studies have documented that severe hemophilia A is also associated with reduced clot stability...
  10. doi request reprint Thrombophilia risk factors are associated with intrauterine foetal death and pregnancy-related venous thromboembolism
    Anne Mette Hvas
    Center for Haemophilia and Thrombosis, Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Denmark
    Scand J Clin Lab Invest 69:288-94. 2009
    ....
  11. ncbi request reprint Holotranscobalamin--a first choice assay for diagnosing early vitamin B deficiency?
    A M Hvas
    Department of Clinical Biochemistry, Aarhus University Hospital, Aarhus C, Denmark
    J Intern Med 257:289-98. 2005
    ..The performance of holotranscobalamin (holoTC) was compared with the other markers of vitamin B12 deficiency, and the influence of age, renal function, and thyroid status was examined...
  12. ncbi request reprint No effect of vitamin B-12 treatment on cognitive function and depression: a randomized placebo controlled study
    Anne Mette Hvas
    Department of Haematology, Aas, Aarhus University Hospital, Aarhus, Denmark
    J Affect Disord 81:269-73. 2004
    ..Associations between vitamin B-12 deficiency and impaired cognitive function and depression have been reported...
  13. ncbi request reprint Vitamin B-12 treatment has limited effect on health-related quality of life among individuals with elevated plasma methylmalonic acid: a randomized placebo-controlled study
    A M Hvas
    Department of Haematology, Aas, Aarhus University Hospital, Aarhus Kommunehospital, Nørrebrogade 44, 8000 Aarhus C, Denmark
    J Intern Med 253:146-52. 2003
    ..To examine the hypothesis that treatment with vitamin B-12 improves health-related quality of life (HRQOL) in individuals with biochemical signs of vitamin B-12 deficiency...
  14. ncbi request reprint Use of plasma methylmalonic acid in diagnosing vitamin B-12 deficiency in general practice
    Anne Mette Hvas
    Department of Haematology, Aarhus University Hospital, Denmark
    Scand J Prim Health Care 20:57-9. 2002
    ..To examine the reasons why general practitioners (GPs) request plasma methylmalonic acid (MMA) tests and how they respond to a result above the reference interval...
  15. ncbi request reprint Health technology assessment in clinical biochemistry. Methylmalonic acid: a Danish showcase
    A M Hvas
    Department of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark
    Scand J Clin Lab Invest 63:319-30. 2003
    ..Our HTA shows that the resources employed to diagnose and to treat vitamin B-12 deficiency have increased considerably, but yet we have no evidence to suggest the clinical benefit...
  16. ncbi request reprint Vitamin B6 level is associated with symptoms of depression
    Anne Mette Hvas
    Department of Clinical Biochemistry, Aarhus University Hospital, AKH, Aarhus, Denmark
    Psychother Psychosom 73:340-3. 2004
    ..In the present study, we examined the association between depression and the phosphate derivative of vitamin B6 in plasma, pyridoxal phosphate (PLP)...
  17. ncbi request reprint [Diagnosis of vitamin B12 deficiency--time for reflection]
    Anne Mette Hvas
    Klinisk Biokemisk Afdeling, Arhus Kommunehospital, DK 8000 Arhus C
    Ugeskr Laeger 165:1971-6. 2003
    ..For patients who also have an MMA in the grey area (0.29-0.75 mumol/l) we recommend that the patient is re-examined after about a year...
  18. doi request reprint Patients with previous definite stent thrombosis have a reduced antiplatelet effect of aspirin and a larger fraction of immature platelets
    Morten Würtz
    Department of Cardiology, Aarhus University Hospital, Skejby, Denmark
    JACC Cardiovasc Interv 3:828-35. 2010
    ..This study sought to evaluate the platelet response to aspirin and the immature platelet fraction in patients with previous stent thrombosis (ST)...
  19. doi request reprint The vitamin B12 absorption test, CobaSorb, identifies patients not requiring vitamin B12 injection therapy
    Anne Mette Hvas
    Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Denmark
    Scand J Clin Lab Invest 71:432-8. 2011
    ..Treatment with vitamin B12 has virtually no side effects; however, life-long treatment is inconvenient for the patient and constitutes a cost for society...
  20. doi request reprint Platelet aggregation is dependent on platelet count in patients with coronary artery disease
    Morten Würtz
    Department of Cardiology, Aarhus University Hospital, Skejby, Denmark
    Thromb Res 129:56-61. 2012
    ..This study investigated the importance of platelet count, haematocrit, red blood cells (RBC), and white blood cells in whole blood platelet aggregometry...
  21. doi request reprint A comparison of platelet function tests and thromboxane metabolites to evaluate aspirin response in healthy individuals and patients with coronary artery disease
    Erik Lerkevang Grove
    Department of Cardiology, Aarhus University Hospital, Skejby, Aarhus, Denmark
    Thromb Haemost 103:1245-53. 2010
    ..This study demonstrated that conclusions based on platelet function testing strongly depend on the assay used...
  22. doi request reprint Shear-induced platelet aggregation in aspirin-treated patients: initial experience with the novel PlaCor PRT device
    Morten Würtz
    Department of Cardiology, Aarhus University Hospital, Denmark
    Thromb Res 130:753-8. 2012
    ..The novel PlaCor PRT provides a global platelet reactivity test based on shear-induced platelet aggregation. We evaluated the PlaCor PRT and its agreement with two widely used platelet function tests...
  23. doi request reprint Uptake of cobalamin and markers of cobalamin status: a longitudinal study of healthy pregnant women
    Eva Greibe
    Department of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark
    Clin Chem Lab Med 49:1877-82. 2011
    ..Currently, it is unknown whether the decline in plasma cobalamin observed during pregnancy is caused by malabsorption of the vitamin. This study examined cobalamin absorption and markers of cobalamin status during normal pregnancy...
  24. doi request reprint Evaluation of aspirin response by Multiplate whole blood aggregometry and light transmission aggregometry
    Susanne B Pedersen
    Department of Cardiology, Aarhus University Hospital, Skejby, Denmark
    Platelets 20:415-20. 2009
    ..Clinical studies are needed to investigate whether a high platelet aggregation level measured by Multiplate whole blood aggregometry during aspirin treatment is associated with a poor clinical outcome...
  25. ncbi request reprint Quantification of holo-transcobalamin, a marker of vitamin B12 deficiency
    Ebba Nexo
    Department of Clinical Biochemistry, Aarhus University Hospital, DK 8000 Aarhus C, Denmark
    Clin Chem 48:561-2. 2002
  26. ncbi request reprint Pharmacogenetics of the antiplatelet effect of aspirin
    Morten Würtz
    Department of Cardiology, Aarhus University Hospital, Skejby, Brendstrupgaardsvej 100, 8200 Aarhus, Denmark
    Curr Pharm Des 18:5294-308. 2012
    ..The present review outlines the pharmacology of aspirin and provides an overview of specific genetic variations considered to influence the antiplatelet effect of aspirin...
  27. doi request reprint Influence of renal function and platelet turnover on the antiplatelet effect of aspirin
    Morten Würtz
    Department of Cardiology, Aarhus University Hospital, Skejby, Denmark
    Thromb Res 129:434-40. 2012
    ..Kidney disease predisposes to cardiovascular events. This study investigated the influence of renal function and platelet turnover on the antiplatelet effect of aspirin in patients with coronary artery disease...
  28. ncbi request reprint Plasma holotranscobalamin compared with plasma cobalamins for assessment of vitamin B12 absorption; optimisation of a non-radioactive vitamin B12 absorption test (CobaSorb)
    Anne Mette Hvas
    Department of Clinical Biochemistry, Skejby Hospital, Aarhus University Hospital, 8000 Aarhus, Denmark
    Clin Chim Acta 376:150-4. 2007
    ..A recently developed non-radioactive vitamin B(12) absorption test (CobaSorb) was further explored to identify the best marker for reflection of vitamin B(12) absorption and to determine the duration of the test...
  29. doi request reprint Increased platelet aggregation and serum thromboxane levels in aspirin-treated patients with prior myocardial infarction
    Sanne Bøjet Larsen
    Department of Cardiology, Aarhus University Hospital, Denmark
    Thromb Haemost 108:140-7. 2012
    ..Serum thromboxane B2 levels were higher in MI patients than in patients without prior MI. Finally, patients on aspirin before MI onset had higher aggregation levels compared with patients not on aspirin...
  30. doi request reprint Low-dose acetylsalicylic acid therapy monitored with ultra high performance liquid chromatography
    Peter Rubak
    Department of Clinical Biochemistry, Aarhus University Hospital, Denmark
    Clin Biochem 46:988-92. 2013
    ..We validated a new, sensitive assay for analyzing blood levels of ASA and the metabolite salicylic acid (SA)...
  31. doi request reprint Transfusion requirements in 811 patients during and after cardiac surgery: a prospective observational study
    Hanne B Ravn
    Department of Anaesthesia and Intensive Care, Aarhus University Hospital, Aarhus, Denmark
    J Cardiothorac Vasc Anesth 25:36-41. 2011
    ..To identify patients at risk for intra- and postoperative blood product transfusion in a mixed adult cardiac surgical patient population...
  32. doi request reprint The antiplatelet effect of aspirin is reduced by proton pump inhibitors in patients with coronary artery disease
    Morten Würtz
    Department of Cardiology, Aarhus University Hospital, Skejby, Denmark
    Heart 96:368-71. 2010
    ..To evaluate the effect of proton pump inhibitors (PPIs) on the platelet response to aspirin in patients with coronary artery disease (CAD)...
  33. doi request reprint Assessment of vitamin B(12) absorption based on the accumulation of orally administered cyanocobalamin on transcobalamin
    Tore Forsingdal Hardlei
    Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Brendstrupgaardsvej 100, DK 8200 Aarhus N, Denmark
    Clin Chem 56:432-6. 2010
    ..We hypothesize that cyanocobalamin (CNCbl) is absorbed unchanged, thereby allowing measurement of the complex of CNCbl bound to TC (TC-CNCbl) to be used for studying the absorption of the vitamin...
  34. doi request reprint Monitoring aspirin therapy with the Platelet Function Analyzer-100
    Jette Mortensen
    Department of Cardiology, Aarhus University Hospital Skejby, Aarhus, Denmark
    Scand J Clin Lab Invest 68:786-92. 2008
    ..We aimed to assess the reproducibility of the PFA-100 and the agreement with optical platelet aggregometry (OPA) in healthy volunteers and in patients with coronary artery disease (CAD) treated with low-dose aspirin...
  35. ncbi request reprint Autoantibodies against intrinsic factor (IF) measured with an ELISA using recombinant human IF as both catching and detecting reagent
    Ebba Nexo
    Department of Clinical Biochemistry, NBG, As, Aarhus University Hospital, Denmark
    Clin Chem Lab Med 43:351-6. 2005
    ..In conclusion, an ELISA using recombinant IF as both catching and detection reagent seems suitable for the detection of IF autoantibodies in plasma...
  36. ncbi request reprint Holotranscobalamin as a predictor of vitamin B12 status
    Anne Mette Hvas
    Department of Clinical Biochemistry, Aarhus University Hospital, AKH, Aarhus, Denmark
    Clin Chem Lab Med 41:1489-92. 2003
    ..Large-scale clinical studies are warranted in order to clarify the usefulness of holotranscobalamin in the clinical setting...
  37. ncbi request reprint Holo-transcobalamin is an early marker of changes in cobalamin homeostasis. A randomized placebo-controlled study
    Ebba Nexo
    Department of Clinical Biochemistry, AKH, Aarhus University Hospital, DK 8000 Aarhus C, Denmark
    Clin Chem 48:1768-71. 2002
    ..We examined the effect of oral vitamin B(12) treatment on fluctuations in plasma total cobalamin and its binding proteins transcobalamin (TC) and haptocorrin (HC)...
  38. ncbi request reprint Effect of vitamin B12 treatment on haptocorrin
    Anne L Mørkbak
    Department of Clinical Biochemistry, Aarhus Sygehus, Denmark
    Clin Chem 52:1104-11. 2006
    ..Haptocorrin (HC) carries the major part of circulating cobalamin, but whether HC is altered on treatment with vitamin B12 remains unknown...
  39. ncbi request reprint Holotranscobalamin remains unchanged during pregnancy. Longitudinal changes of cobalamins and their binding proteins during pregnancy and postpartum
    Anne L Morkbak
    Dept of Clinical Biochemistry, Aarhus University Hospital, Aarhus Sygehus, Denmark
    Haematologica 92:1711-2. 2007
    ..The decrease in cobalamins is explained by a decreased holohaptocorrin (holoHC), suggesting that holoTC rather than cobalamins should be used as a marker of vitamin B12 deficiency during pregnancy...
  40. doi request reprint Can RoTEM® analysis be applied for haemostatic monitoring in paediatric congenital heart surgery?
    Jo Bønding Andreasen
    Department of Anaesthesiology and Intensive Care, Centre for Haemophilia and Thrombosis, Aarhus University Hospital, Skejby, Denmark
    Cardiol Young 21:684-91. 2011
    ..Whole-blood rotation thromboelastometry (RoTEM®) provides continuous qualitative haemostatic profiles, and the technique has shown promising results in adult cardiac surgery...
  41. ncbi request reprint Evaluation of the technical performance of novel holotranscobalamin (holoTC) assays in a multicenter European demonstration project
    Anne L Morkbak
    Department of Clinical Biochemistry, As, Aarhus University Hospital, Aarhus, Denmark
    Clin Chem Lab Med 43:1058-64. 2005
    ..The results obtained using the holoTC RIA were similar to those obtained using the holoTC ELISA assay...
  42. pmc Fibrin clot structure and platelet aggregation in patients with aspirin treatment failure
    Søs Neergaard-Petersen
    Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark Division of Cardiovascular and Diabetes Research, Leeds Institute for Genetics, Health and Therapeutics, University of Leeds, Leeds, United Kingdom
    PLoS ONE 8:e71150. 2013
    ..Some patients experience cardiovascular events whilst on aspirin, often termed aspirin treatment failure (ATF). This study evaluated both platelet aggregation and fibrin clot structure in patients with ATF...
  43. doi request reprint Reference intervals for platelet aggregation assessed by multiple electrode platelet aggregometry
    Peter Rubak
    Department of Clinical Biochemistry, Aarhus University Hospital, Denmark
    Thromb Res 130:420-3. 2012
    ..Reference intervals for the most commonly used agonists were established, and the association between platelet aggregation, age, gender and haematological values was analysed...
  44. ncbi request reprint Reference intervals for haematological variables during normal pregnancy and postpartum in 434 healthy Danish women
    Nils Milman
    Department of Obstetrics, Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark
    Eur J Haematol 79:39-46. 2007
    ..To report reference intervals for haematological variables during normal pregnancy and postpartum...
  45. doi request reprint Platelet turnover in stable coronary artery disease - influence of thrombopoietin and low-grade inflammation
    Sanne Bøjet Larsen
    Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark
    PLoS ONE 9:e85566. 2014
    ..Newly formed platelets are associated with increased aggregation and adverse outcomes in patients with coronary artery disease (CAD). The mechanisms involved in the regulation of platelet turnover in patients with CAD are largely unknown...
  46. ncbi request reprint Immature platelets in patients with acute coronary syndromes
    Erik Lerkevang Grove
    Department of Cardiology, Aarhus University Hospital Skejby, Brendstrupgaardsvej 100, DK 8200 Aarhus N, Denmark
    Thromb Haemost 101:151-6. 2009
    ..In conclusion, the fraction of immature platelets is increased in acute coronary syndromes, especially in the acute phase of STEMI. Immature platelets with an increased haemostatic potential may contribute to coronary thrombus formation...
  47. ncbi request reprint Holo-transcobalamin concentration and transcobalamin saturation reflect recent vitamin B12 absorption better than does serum vitamin B12
    Mustafa Vakur Bor
    Department of Clinical Biochemistry, AKH, Aarhus University Hospital, Norrebrogade 44, DK 8000 Aarhus C, Denmark
    Clin Chem 50:1043-9. 2004
    ..We evaluated whether measurement of vitamin B(12)-saturated transcobalamin (holo-TC) concentrations or TC saturation (holo-TC:total TC) reflects active vitamin B(12) absorption in healthy individuals and patients after vitamin B(12) intake...
  48. doi request reprint Increased platelet aggregation and turnover in the acute phase of ST-elevation myocardial infarction
    Kristian Løkke Funck-Jensen
    Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark
    Platelets 24:528-37. 2013
    ..Increased platelet turnover may partly explain the reduced efficacy of antiplatelet drugs in the acute phase of STEMI...
  49. doi request reprint Changes in fibrin D-dimer, fibrinogen, and protein S during pregnancy
    Anette Tarp Hansen
    Department of Clinical Biochemistry, Center of Hemophilia and Thrombosis, Aarhus University Hospital, Skejby, Denmark
    Scand J Clin Lab Invest 71:173-6. 2011
    ..Objectives. The aim of the present study was to contribute to the establishment of reference intervals for D-dimer, fibrinogen and protein S during pregnancy and to discuss the use of the analyses during pregnancy...
  50. doi request reprint Marked changes in platelet count and function following pediatric congenital heart surgery
    Jo Bønding Andreasen
    Department of Anaesthesiology and Intensive Care, Aarhus University Hospital, Aarhus N, Denmark
    Paediatr Anaesth 24:386-92. 2014
    ..The purpose of the present study was to evaluate platelet count and function in children following CPB...
  51. ncbi request reprint Body iron and individual iron prophylaxis in pregnancy--should the iron dose be adjusted according to serum ferritin?
    Nils Milman
    Department of Obstetrics, Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark
    Ann Hematol 85:567-73. 2006
    ..In the prevention of IDA, we suggest 40 mg ferrous iron/day to women having ferritin <or=70 microg/l. Women with ferritin >70 microg/l have no need for iron supplement...
  52. ncbi request reprint Cobalamin status during normal pregnancy and postpartum: a longitudinal study comprising 406 Danish women
    Nils Milman
    Department of Obstetrics, Gentofte Hospital, University of Copenhagen, Denmark
    Eur J Haematol 76:521-5. 2006
    ..To assess cobalamin (vitamin B(12)) status during normal pregnancy and postpartum in a longitudinal setting...
  53. ncbi request reprint Holotranscobalamin as an indicator of dietary vitamin B12 deficiency
    Zouë Lloyd-Wright
    Nutrition Food and Health Research Centre, King s College London, Franklin Wilkins Bldg, 150 Stamford St, Waterloo, London SE1 9NN, United Kingdom
    Clin Chem 49:2076-8. 2003
  54. ncbi request reprint Erythrocyte folate, plasma folate and plasma homocysteine during normal pregnancy and postpartum: a longitudinal study comprising 404 Danish women
    Nils Milman
    Department of Obstetrics, Gentofte Hospital, University of Copenhagen, Denmark
    Eur J Haematol 76:200-5. 2006
    ..To assess folate and homocysteine status during normal pregnancy and postpartum in a longitudinal setting...
  55. ncbi request reprint Health technology assessment: a "must" for laboratory medicine?
    Anne Mette Hvas
    Scand J Clin Lab Invest 63:317-8. 2003