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Genomes and Genes | Bent HonoréSummaryAffiliation: University of Aarhus Country: Denmark Publications
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Publications
The rapidly expanding CREC protein family: members, localization, function, and role in diseaseBent Honoré
Department of Medical Biochemistry, Aarhus University, Aarhus C, Denmark
Bioessays 31:262-77. 2009..Other functions concern participation in the secretory process, chaperone activity, signal transduction as well as participation in a large variety of disease processes...
Identification of differentially expressed proteins in spontaneous thymic lymphomas from knockout mice with deletion of p53Bent Honoré
Institute of Medical Biochemistry, University of Aarhus, Denmark
Proteome Sci 6:18. 2008..Two cell lines (SM5 and SM7), established from two independent tumours, exhibited about fifty to seventy two-fold differentially expressed proteins compared to wild type thymocytes by two-dimensional gel electrophoresis (2D-PAGE)...- Attempting to distinguish between endogenous and contaminating cytokeratins in a corneal proteomic studyMikkel Lyngholm
Department of Ophthalmology, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark
BMC Ophthalmol 11:3. 2011..This issue is especially important in proteomic studies of the corneal epithelium where several CK's have previously been reported to mark the stages of differentiation from corneal epithelial stem cell to the differentiated cell... 
hnRNPs H, H' and F behave differently with respect to posttranslational cleavage and subcellular localizationB Honore
Department of Medical Biochemistry, Ole Worms Alle, University of Aarhus, Denmark
FEBS Lett 456:274-80. 1999..The presence of significant quantities of hnRNP F in the cytoplasm of many cells indicates that it also may have a functional role here...- Proteomic profiling of peritoneal rinse fluid sediment separates patients with ovarian cancer from women admitted for cesarean section. A pilot studyBent Honoré
Department of Medical Biochemistry, Aarhus University, Aarhus C, Denmark
Scand J Clin Lab Invest 70:470-7. 2010..There is a great need for additional approaches to discover putative biomarkers for ovarian cancer that accounts for 5% of all cancer deaths among women and is the leading cause of deaths among gynecologic malignancies in the United States... - Functional genomics studied by proteomicsBent Honoré
Department of Medical Biochemistry, University of Aarhus, Aarhus C, Denmark
Bioessays 26:901-15. 2004..The strengths and weaknesses of these techniques are discussed... - [Benign paroxysmal positional vertigo. Easy to diagnose--easy to treat]Bent Honoré
Ugeskr Laeger 166:1236-8. 2004 - Changes in protein expression in p53 deleted spontaneous thymic lymphomasBent Honoré
Department of Medical Biochemistry, University of Aarhus, DK 8000 Aarhus C, Denmark
Exp Cell Res 295:91-101. 2004.... - Heterogeneous nuclear ribonucleoproteins F and H/H' show differential expression in normal and selected cancer tissuesBent Honoré
Department of Medical Biochemistry, University of Aarhus, DK 8000 Aarhus C, Denmark
Exp Cell Res 294:199-209. 2004..hnRNP F is down-regulated in hepatocellular carcinoma and up-regulated in gastric carcinoma. The present study indicates the important potential role of this subset of hnRNPs on the gene expression in many tissues... - Genome- and proteome-based technologies: status and applications in the postgenomic eraB Honore
Department of Medical Biochemistry, Ole Worms Alle, Building 170, University of Aarhus, DK 8000 Aarhus C, Denmark
Expert Rev Mol Diagn 1:265-74. 2001..The combination of 2-dimensional polyacrylamide gel electrophoresis and mass spectrometry analyses make a strong couple that may enter as diagnostic applications once more automated... - Endonuclein is a cell cycle regulated WD-repeat protein that is up-regulated in adenocarcinoma of the pancreasBent Honoré
Department of Medical Biochemistry, Ole Worms Alle, Building 170, University of Aarhus, DK 8000 Aarhus C, Denmark
Oncogene 21:1123-9. 2002..Ultrastructural analysis revealed ER and nuclear localization. Endonuclein contains five WD-repeats, indicating a putative role in crucial regulatory activities in the nucleus as well as in the ER... - The hnRNP 2H9 gene, which is involved in the splicing reaction, is a multiply spliced geneB Honore
Department of Medical Biochemistry, University of Aarhus, Ole Worms Alle, Bldg 170, DK 8000 Aarhus C, Denmark
Biochim Biophys Acta 1492:108-19. 2000..Due to their great structural variations the different proteins may thus possess different functions in the splicing reaction... - The CREC family, a novel family of multiple EF-hand, low-affinity Ca(2+)-binding proteins localised to the secretory pathway of mammalian cellsB Honore
Department of Medical Biochemistry, University of Aarhus, Ole Worms Alle, Building 170, DK 8000, Aarhus, Denmark
FEBS Lett 466:11-8. 2000.... - Proteomic analysis identifies galectin-1 as a predictive biomarker for relapsed/refractory disease in classical Hodgkin lymphomaPeter Kamper
Department of Hematology, Arhus University Hospital, Tage Hansens Gade 2, Aarhus C, Denmark
Blood 117:6638-49. 2011..Therefore, in addition to its functional role in cHL-induced immunosuppression, Gal-1 is also associated with an adverse clinical outcome in this disease... - Proteomic analysis identifies mitochondrial metabolic enzymes as major discriminators between different stages of the failing human myocardiumSigitas Urbonavicius
Institute of Medical Biochemistry, University of Aarhus, Denmark
Acta Cardiol 64:511-22. 2009..We specifically studied proteomics in chronic reversibly (RDM) and irreversibly dysfunctional myocardium (IRDM), as well as end-stage failing myocardium (ESFM)... - Pulmonary pressure reduction attenuates expression of proteins identified by lung proteomic profiling in pulmonary hypertensive ratsLouise Østergaard
Department of Biomedicine, Aarhus University, Aarhus C, Denmark
Proteomics 11:4492-502. 2011..These findings suggest that pulmonary pressure is an important factor for initiating signaling pathways leading to protein expression and muscularization in the pulmonary vasculature... - Identification and characterization of endonuclein binding proteins: evidence of modulatory effects on signal transduction and chaperone activityMaja Ludvigsen
Department of Medical Biochemistry, Aarhus University, Ole Worms Allé 3, Building 1170, Aarhus, DK 8000 Aarhus C, Denmark
BMC Biochem 10:34. 2009..We have previously identified endonuclein as a cell cycle regulated WD-repeat protein that is up-regulated in adenocarcinoma of the pancreas. Now, we aim to investigate its biomedical functions... - Identification and characterization of novel ERC-55 interacting proteins: evidence for the existence of several ERC-55 splicing variants; including the cytosolic ERC-55-CMaja Ludvigsen
Department of Medical Biochemistry, Aarhus University, Aarhus, Denmark
Proteomics 9:5267-87. 2009..The functional variety of the interacting proteins indicates a broad spectrum of ERC-55 activities such as immunity, redox homeostasis, cell cycle regulation and coagulation... - Proteomics reveals lowering oxygen alters cytoskeletal and endoplasmatic stress proteins in human endothelial cellsLouise Ostergaard
Department of Pharmacology, University of Aarhus, 8000 Aarhus C, Denmark
Proteomics 9:4457-67. 2009..g. cofilin-1, tubulin, and beta-actin) and in ER stress/apoptosis (e.g. Grp78/94, caspase 12, and cyclophilin A)... - Suppressed phospholamban levels differentiate irreversibly dysfunctional from hibernating myocardium in humansHenrik Wiggers
Department of Cardiology, Skejby Hospital, Aarhus University Hospitals, Aarhus, Denmark
Scand Cardiovasc J 39:55-9. 2005.... - Proteomic profiling of fibroblasts reveals a modulating effect of extracellular calumenin on the organization of the actin cytoskeletonMorten Ostergaard
Institute of Medical Biochemistry, Ole Worms All, University of Aarhus, Denmark
Proteomics 6:3509-19. 2006..Our study thus indicates that calumenin may have an autocrine or a paracrine effect on the cells in its vicinity, and, therefore, may be involved in the pathophysiology of thrombosis or in wound healing... - Identification of differentially regulated proteins in a patient with Leber's Congenital Amaurosis--a proteomic studyHenrik Vorum
Department of Ophthalmology, Aarhus University Hospital, Nørrebrogade 44, DK 8000 Aarhus C, Denmark
Proteome Sci 5:5. 2007..The tissue was subjected to high resolution two-dimensional gel electrophoresis, image analysis and mass spectrometry, in an effort to identify differentially regulated proteins... - Ca2+ binding to complement-type repeat domains 5 and 6 from the low-density lipoprotein receptor-related proteinOlav M Andersen
Laboratory of Gene Expression, Department of Molecular and Structural Biology, University of Aarhus, DK 8000 Aarhus C, Denmark
BMC Biochem 4:7. 2003.... - Tumor-infiltrating macrophages correlate with adverse prognosis and Epstein-Barr virus status in classical Hodgkin's lymphomaPeter Kamper
Department of Hematology, Aarhus University Hospital, Tage Hansens Gade 2 DK 8000, Aarhus C, Denmark
Haematologica 96:269-76. 2011..The aim of our study was to correlate expression of CD68 and CD163 with the clinico-pathological features and prognosis of a cohort of patients with previously untreated Hodgkin's lymphoma... - Calumenin but not reticulocalbin forms a Ca2+-dependent complex with thrombospondin-1. A potential role in haemostasis and thrombosisGry Aune Westergaard Hansen
Institute of Medical Biochemistry, University of Aarhus, Ole Worms Alle, Building 1170, 8000 Aarhus C, Denmark
Mol Cell Biochem 320:25-33. 2009..This further indicates that calumenin may be broadly involved in haemostasis and in the pathophysiology of thrombosis...