Bent Honoré

Summary

Affiliation: University of Aarhus
Country: Denmark

Publications

  1. doi request reprint The rapidly expanding CREC protein family: members, localization, function, and role in disease
    Bent Honoré
    Department of Medical Biochemistry, Aarhus University, Aarhus C, Denmark
    Bioessays 31:262-77. 2009
  2. pmc Identification of differentially expressed proteins in spontaneous thymic lymphomas from knockout mice with deletion of p53
    Bent Honoré
    Institute of Medical Biochemistry, University of Aarhus, Denmark
    Proteome Sci 6:18. 2008
  3. pmc Attempting to distinguish between endogenous and contaminating cytokeratins in a corneal proteomic study
    Mikkel Lyngholm
    Department of Ophthalmology, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark
    BMC Ophthalmol 11:3. 2011
  4. ncbi request reprint hnRNPs H, H' and F behave differently with respect to posttranslational cleavage and subcellular localization
    B Honore
    Department of Medical Biochemistry, Ole Worms Alle, University of Aarhus, Denmark
    FEBS Lett 456:274-80. 1999
  5. doi request reprint Proteomic profiling of peritoneal rinse fluid sediment separates patients with ovarian cancer from women admitted for cesarean section. A pilot study
    Bent Honoré
    Department of Medical Biochemistry, Aarhus University, Aarhus C, Denmark
    Scand J Clin Lab Invest 70:470-7. 2010
  6. ncbi request reprint Functional genomics studied by proteomics
    Bent Honoré
    Department of Medical Biochemistry, University of Aarhus, Aarhus C, Denmark
    Bioessays 26:901-15. 2004
  7. ncbi request reprint [Benign paroxysmal positional vertigo. Easy to diagnose--easy to treat]
    Bent Honoré
    Ugeskr Laeger 166:1236-8. 2004
  8. ncbi request reprint Changes in protein expression in p53 deleted spontaneous thymic lymphomas
    Bent Honoré
    Department of Medical Biochemistry, University of Aarhus, DK 8000 Aarhus C, Denmark
    Exp Cell Res 295:91-101. 2004
  9. ncbi request reprint Heterogeneous nuclear ribonucleoproteins F and H/H' show differential expression in normal and selected cancer tissues
    Bent Honoré
    Department of Medical Biochemistry, University of Aarhus, DK 8000 Aarhus C, Denmark
    Exp Cell Res 294:199-209. 2004
  10. ncbi request reprint Genome- and proteome-based technologies: status and applications in the postgenomic era
    B Honore
    Department of Medical Biochemistry, Ole Worms Alle, Building 170, University of Aarhus, DK 8000 Aarhus C, Denmark
    Expert Rev Mol Diagn 1:265-74. 2001

Collaborators

Detail Information

Publications25

  1. doi request reprint The rapidly expanding CREC protein family: members, localization, function, and role in disease
    Bent Honoré
    Department of Medical Biochemistry, Aarhus University, Aarhus C, Denmark
    Bioessays 31:262-77. 2009
    ..Other functions concern participation in the secretory process, chaperone activity, signal transduction as well as participation in a large variety of disease processes...
  2. pmc Identification of differentially expressed proteins in spontaneous thymic lymphomas from knockout mice with deletion of p53
    Bent Honoré
    Institute of Medical Biochemistry, University of Aarhus, Denmark
    Proteome Sci 6:18. 2008
    ..Two cell lines (SM5 and SM7), established from two independent tumours, exhibited about fifty to seventy two-fold differentially expressed proteins compared to wild type thymocytes by two-dimensional gel electrophoresis (2D-PAGE)...
  3. pmc Attempting to distinguish between endogenous and contaminating cytokeratins in a corneal proteomic study
    Mikkel Lyngholm
    Department of Ophthalmology, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark
    BMC Ophthalmol 11:3. 2011
    ..This issue is especially important in proteomic studies of the corneal epithelium where several CK's have previously been reported to mark the stages of differentiation from corneal epithelial stem cell to the differentiated cell...
  4. ncbi request reprint hnRNPs H, H' and F behave differently with respect to posttranslational cleavage and subcellular localization
    B Honore
    Department of Medical Biochemistry, Ole Worms Alle, University of Aarhus, Denmark
    FEBS Lett 456:274-80. 1999
    ..The presence of significant quantities of hnRNP F in the cytoplasm of many cells indicates that it also may have a functional role here...
  5. doi request reprint Proteomic profiling of peritoneal rinse fluid sediment separates patients with ovarian cancer from women admitted for cesarean section. A pilot study
    Bent Honoré
    Department of Medical Biochemistry, Aarhus University, Aarhus C, Denmark
    Scand J Clin Lab Invest 70:470-7. 2010
    ..There is a great need for additional approaches to discover putative biomarkers for ovarian cancer that accounts for 5% of all cancer deaths among women and is the leading cause of deaths among gynecologic malignancies in the United States...
  6. ncbi request reprint Functional genomics studied by proteomics
    Bent Honoré
    Department of Medical Biochemistry, University of Aarhus, Aarhus C, Denmark
    Bioessays 26:901-15. 2004
    ..The strengths and weaknesses of these techniques are discussed...
  7. ncbi request reprint [Benign paroxysmal positional vertigo. Easy to diagnose--easy to treat]
    Bent Honoré
    Ugeskr Laeger 166:1236-8. 2004
  8. ncbi request reprint Changes in protein expression in p53 deleted spontaneous thymic lymphomas
    Bent Honoré
    Department of Medical Biochemistry, University of Aarhus, DK 8000 Aarhus C, Denmark
    Exp Cell Res 295:91-101. 2004
    ....
  9. ncbi request reprint Heterogeneous nuclear ribonucleoproteins F and H/H' show differential expression in normal and selected cancer tissues
    Bent Honoré
    Department of Medical Biochemistry, University of Aarhus, DK 8000 Aarhus C, Denmark
    Exp Cell Res 294:199-209. 2004
    ..hnRNP F is down-regulated in hepatocellular carcinoma and up-regulated in gastric carcinoma. The present study indicates the important potential role of this subset of hnRNPs on the gene expression in many tissues...
  10. ncbi request reprint Genome- and proteome-based technologies: status and applications in the postgenomic era
    B Honore
    Department of Medical Biochemistry, Ole Worms Alle, Building 170, University of Aarhus, DK 8000 Aarhus C, Denmark
    Expert Rev Mol Diagn 1:265-74. 2001
    ..The combination of 2-dimensional polyacrylamide gel electrophoresis and mass spectrometry analyses make a strong couple that may enter as diagnostic applications once more automated...
  11. ncbi request reprint Endonuclein is a cell cycle regulated WD-repeat protein that is up-regulated in adenocarcinoma of the pancreas
    Bent Honoré
    Department of Medical Biochemistry, Ole Worms Alle, Building 170, University of Aarhus, DK 8000 Aarhus C, Denmark
    Oncogene 21:1123-9. 2002
    ..Ultrastructural analysis revealed ER and nuclear localization. Endonuclein contains five WD-repeats, indicating a putative role in crucial regulatory activities in the nucleus as well as in the ER...
  12. ncbi request reprint The hnRNP 2H9 gene, which is involved in the splicing reaction, is a multiply spliced gene
    B Honore
    Department of Medical Biochemistry, University of Aarhus, Ole Worms Alle, Bldg 170, DK 8000 Aarhus C, Denmark
    Biochim Biophys Acta 1492:108-19. 2000
    ..Due to their great structural variations the different proteins may thus possess different functions in the splicing reaction...
  13. ncbi request reprint The CREC family, a novel family of multiple EF-hand, low-affinity Ca(2+)-binding proteins localised to the secretory pathway of mammalian cells
    B Honore
    Department of Medical Biochemistry, University of Aarhus, Ole Worms Alle, Building 170, DK 8000, Aarhus, Denmark
    FEBS Lett 466:11-8. 2000
    ....
  14. doi request reprint Proteomic analysis identifies galectin-1 as a predictive biomarker for relapsed/refractory disease in classical Hodgkin lymphoma
    Peter Kamper
    Department of Hematology, Arhus University Hospital, Tage Hansens Gade 2, Aarhus C, Denmark
    Blood 117:6638-49. 2011
    ..Therefore, in addition to its functional role in cHL-induced immunosuppression, Gal-1 is also associated with an adverse clinical outcome in this disease...
  15. ncbi request reprint Proteomic analysis identifies mitochondrial metabolic enzymes as major discriminators between different stages of the failing human myocardium
    Sigitas Urbonavicius
    Institute of Medical Biochemistry, University of Aarhus, Denmark
    Acta Cardiol 64:511-22. 2009
    ..We specifically studied proteomics in chronic reversibly (RDM) and irreversibly dysfunctional myocardium (IRDM), as well as end-stage failing myocardium (ESFM)...
  16. ncbi request reprint Proteomic profiling of fibroblasts reveals a modulating effect of extracellular calumenin on the organization of the actin cytoskeleton
    Morten Ostergaard
    Institute of Medical Biochemistry, Ole Worms Alle, University of Aarhus, Denmark
    Proteomics 6:3509-19. 2006
    ..Our study thus indicates that calumenin may have an autocrine or a paracrine effect on the cells in its vicinity, and, therefore, may be involved in the pathophysiology of thrombosis or in wound healing...
  17. doi request reprint Pulmonary pressure reduction attenuates expression of proteins identified by lung proteomic profiling in pulmonary hypertensive rats
    Louise Østergaard
    Department of Biomedicine, Aarhus University, Aarhus C, Denmark
    Proteomics 11:4492-502. 2011
    ..These findings suggest that pulmonary pressure is an important factor for initiating signaling pathways leading to protein expression and muscularization in the pulmonary vasculature...
  18. pmc Identification and characterization of endonuclein binding proteins: evidence of modulatory effects on signal transduction and chaperone activity
    Maja Ludvigsen
    Department of Medical Biochemistry, Aarhus University, Ole Worms Allé 3, Building 1170, Aarhus, DK 8000 Aarhus C, Denmark
    BMC Biochem 10:34. 2009
    ..We have previously identified endonuclein as a cell cycle regulated WD-repeat protein that is up-regulated in adenocarcinoma of the pancreas. Now, we aim to investigate its biomedical functions...
  19. doi request reprint Identification and characterization of novel ERC-55 interacting proteins: evidence for the existence of several ERC-55 splicing variants; including the cytosolic ERC-55-C
    Maja Ludvigsen
    Department of Medical Biochemistry, Aarhus University, Aarhus, Denmark
    Proteomics 9:5267-87. 2009
    ..The functional variety of the interacting proteins indicates a broad spectrum of ERC-55 activities such as immunity, redox homeostasis, cell cycle regulation and coagulation...
  20. doi request reprint Proteomics reveals lowering oxygen alters cytoskeletal and endoplasmatic stress proteins in human endothelial cells
    Louise Ostergaard
    Department of Pharmacology, University of Aarhus, 8000 Aarhus C, Denmark
    Proteomics 9:4457-67. 2009
    ..g. cofilin-1, tubulin, and beta-actin) and in ER stress/apoptosis (e.g. Grp78/94, caspase 12, and cyclophilin A)...
  21. ncbi request reprint Suppressed phospholamban levels differentiate irreversibly dysfunctional from hibernating myocardium in humans
    Henrik Wiggers
    Department of Cardiology, Skejby Hospital, Aarhus University Hospitals, Aarhus, Denmark
    Scand Cardiovasc J 39:55-9. 2005
    ....
  22. pmc Identification of differentially regulated proteins in a patient with Leber's Congenital Amaurosis--a proteomic study
    Henrik Vorum
    Department of Ophthalmology, Aarhus University Hospital, Nørrebrogade 44, DK 8000 Aarhus C, Denmark
    Proteome Sci 5:5. 2007
    ..The tissue was subjected to high resolution two-dimensional gel electrophoresis, image analysis and mass spectrometry, in an effort to identify differentially regulated proteins...
  23. pmc Ca2+ binding to complement-type repeat domains 5 and 6 from the low-density lipoprotein receptor-related protein
    Olav M Andersen
    Laboratory of Gene Expression, Department of Molecular and Structural Biology, University of Aarhus, DK 8000 Aarhus C, Denmark
    BMC Biochem 4:7. 2003
    ....
  24. doi request reprint Calumenin but not reticulocalbin forms a Ca2+-dependent complex with thrombospondin-1. A potential role in haemostasis and thrombosis
    Gry Aune Westergaard Hansen
    Institute of Medical Biochemistry, University of Aarhus, Ole Worms Alle, Building 1170, 8000 Aarhus C, Denmark
    Mol Cell Biochem 320:25-33. 2009
    ..This further indicates that calumenin may be broadly involved in haemostasis and in the pathophysiology of thrombosis...
  25. pmc Tumor-infiltrating macrophages correlate with adverse prognosis and Epstein-Barr virus status in classical Hodgkin's lymphoma
    Peter Kamper
    Department of Hematology, Aarhus University Hospital, Tage Hansens Gade 2 DK 8000, Aarhus C, Denmark
    Haematologica 96:269-76. 2011
    ..The aim of our study was to correlate expression of CD68 and CD163 with the clinico-pathological features and prognosis of a cohort of patients with previously untreated Hodgkin's lymphoma...