K Holte

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..In this study we investigated the effects of two levels of intravascular fluid administration ("liberal" versus "restrictive") in knee arthroplasty on physiological recovery as the primary outcome variable...

..Finally, we have demonstrated that the conduction of double-blinded randomized trials on fluid management with postoperative outcomes is feasible...

..However, no long-term information or measurements of plasma volumes with or without hypotension after epidural anesthesia are available...

..The objective of this study was to investigate the effects of 2 levels of intraoperative fluid administration on perioperative physiology and outcome after laparoscopic cholecystectomy...

..These findings may serve as basis information for clinical studies of perioperative fluid management...

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..We therefore examined the association between perioperatively administered fluids aiming to correct dehydration and clinical outcome...

..Therefore, we investigated the effects of two regimens of intraoperative fluids with physiological recovery as the primary outcome measure after fast-track colonic surgery...

..Future studies should be procedure-specific and with standardized perioperative management with increased focus on the postoperative period...

..This study determined the rate of anastomotic leakage in a series of patients who had colonic surgery over a 9-year period with or without use of a cyclo-oxygenase inhibitor for postoperative analgesia...

..Future evaluation of the effects of epidural analgesia on postoperative outcome also requires integration of epidural analgesia within a multimodal rehabilitation programme...

..The potential of selective opioid antagonists and intravenous lidocaine should be further investigated, particularly in conjunction with laparoscopic surgery, epidural pain management and fast-track surgery...

..For most major BDIs, the recommended method of repair is a hepaticojejunostomy (HJ). We conducted a retrospective review aiming to examine the perioperative and the long-term outcome after reconstructive HJ at our institution...

..This study was designed to investigate the physiologic effects of bowel preparation...

..However, relatively few patients have been included in randomized trials, indicating a need for more studies to secure valid conclusions...

..The aim of the study was to examine the analgesic effects of the anticonvulsant, gabapentin, in a validated model of acute inflammatory pain...

..Future studies, including those incorporating investigational agents, such as kappa-opioid agonists and peripheral mu-opioid antagonists, into a multimodal regimen, may offer new treatment options to further impact POI duration...

..It is unknown whether an intra-operative colloid infusion alters the dynamics of a crystalloid load administered post-operatively...

..CONCLUSION: Changes of postoperative position from supine to sitting or standing are of major importance in the interpretation of postoperative pulmonary outcome studies and in future strategies to improve pulmonary outcome...

..CONCLUSIONS: Epidural local anaesthetics should be included in a multi-modal rehabilitation programme after major surgical procedures in order to facilitate oral nutrition, improve recovery and reduce morbidity...

..A multi-modal rehabilitation programme including continuous epidural analgesia with local anaesthetics, enforced nutrition and mobilisation may reduce PI to 1-2 days after colonic surgery...

..In this paper, we describe VAC as a method for treating anastomotic leakage after rectal resection...

..CONCLUSIONS: Addition of small amounts of dexamethasone to bupivacaine incorporated in microcapsules prolonged local analgesia compared with microcapsules with plain bupivacaine after subcutaneous administration in humans...

..No serious side effects were observed for up to 6 mo after administration. In conclusion, bupivacaine incorporated in microcapsules provided analgesia for 96 h after subcutaneous infiltration...

..A new pain questionnaire should be simple, be documented to have discriminative function, and be related to previously used questionnaires...

..Laparotomy showed that the IUD had perforated the uterus and penetrated the sigmoid colon. Resection was performed. This case demonstrates the need to investigate every case of a missing IUD...