K Hojlund

Summary

Affiliation: University of Copenhagen
Country: Denmark

Publications

  1. doi Characterisation of adiponectin multimers and the IGF axis in humans with a heterozygote mutation in the tyrosine kinase domain of the insulin receptor gene
    Kurt Højlund
    Department of Endocrinology, Diabetes Research Centre, Odense University Hospital, Kløvervænget 6, DK 5000 Odense C, Denmark
    Eur J Endocrinol 166:511-9. 2012
  2. doi Human ATP synthase beta is phosphorylated at multiple sites and shows abnormal phosphorylation at specific sites in insulin-resistant muscle
    K Højlund
    Center for Metabolic Biology, School of Life Sciences, Arizona State University, PO Box 87370, Tempe, AZ 85287, USA
    Diabetologia 53:541-51. 2010
  3. doi Mitochondrial dysfunction in type 2 diabetes and obesity
    Kurt Højlund
    Diabetes Research Center, Department of Endocrinology, Odense University Hospital, Kloevervaenget 6, 3 DK 5000 Odense C, Denmark
    Endocrinol Metab Clin North Am 37:713-31, x. 2008
  4. ncbi Impaired glycogen synthase activity and mitochondrial dysfunction in skeletal muscle: markers or mediators of insulin resistance in type 2 diabetes?
    Kurt Højlund
    Diabetes Research Centre, Department of Endocrinology, Odense University Hospital, Odense, Denmark
    Curr Diabetes Rev 2:375-95. 2006
  5. ncbi Impaired insulin-stimulated phosphorylation of Akt and AS160 in skeletal muscle of women with polycystic ovary syndrome is reversed by pioglitazone treatment
    Kurt Højlund
    Department of Endocrinology, Odense University Hospital, Kloevervaenget 6, DK 5000 Odense C, Denmark
    Diabetes 57:357-66. 2008
  6. ncbi Energy expenditure, body composition and insulin response to glucose in male twins discordant for the Trp64Arg polymorphism of the beta3-adrenergic receptor gene
    K Højlund
    Diabetes Research Centre, Department of Endocrinology, Odense University Hospital, Odense, Denmark
    Diabetes Obes Metab 8:322-30. 2006
  7. ncbi Reduced plasma adiponectin concentrations may contribute to impaired insulin activation of glycogen synthase in skeletal muscle of patients with type 2 diabetes
    K Højlund
    Diabetes Research Centre, Department of Endocrinology, Odense University Hospital, Odense, Denmark
    Diabetologia 49:1283-91. 2006
  8. ncbi A novel syndrome of autosomal-dominant hyperinsulinemic hypoglycemia linked to a mutation in the human insulin receptor gene
    Kurt Højlund
    Diabetes Research Centre, Department of Endocrinology, Odense University Hospital, Kloevervaenget 6, DK 5000, Odense C, Denmark
    Diabetes 53:1592-8. 2004
  9. ncbi Effect of insulin on protein phosphatase 2A expression in muscle in type 2 diabetes
    K Højlund
    Department of Endocrinology, Odense University Hospital, Odense C, Denmark
    Eur J Clin Invest 32:918-23. 2002
  10. ncbi Reference intervals for glucose, beta-cell polypeptides, and counterregulatory factors during prolonged fasting
    K Hojlund
    Diabetes Centre, Department of Endocrinology, Odense University Hospital, DK 5000 Odense C, Denmark
    Am J Physiol Endocrinol Metab 280:E50-8. 2001

Collaborators

Detail Information

Publications11

  1. doi Characterisation of adiponectin multimers and the IGF axis in humans with a heterozygote mutation in the tyrosine kinase domain of the insulin receptor gene
    Kurt Højlund
    Department of Endocrinology, Diabetes Research Centre, Odense University Hospital, Kløvervænget 6, DK 5000 Odense C, Denmark
    Eur J Endocrinol 166:511-9. 2012
    ..Here, we aimed to characterise the multimeric distribution of adiponectin and the IGF axis in humans with a heterozygous INSR mutation (Arg1174Gln)...
  2. doi Human ATP synthase beta is phosphorylated at multiple sites and shows abnormal phosphorylation at specific sites in insulin-resistant muscle
    K Højlund
    Center for Metabolic Biology, School of Life Sciences, Arizona State University, PO Box 87370, Tempe, AZ 85287, USA
    Diabetologia 53:541-51. 2010
    ....
  3. doi Mitochondrial dysfunction in type 2 diabetes and obesity
    Kurt Højlund
    Diabetes Research Center, Department of Endocrinology, Odense University Hospital, Kloevervaenget 6, 3 DK 5000 Odense C, Denmark
    Endocrinol Metab Clin North Am 37:713-31, x. 2008
    ....
  4. ncbi Impaired glycogen synthase activity and mitochondrial dysfunction in skeletal muscle: markers or mediators of insulin resistance in type 2 diabetes?
    Kurt Højlund
    Diabetes Research Centre, Department of Endocrinology, Odense University Hospital, Odense, Denmark
    Curr Diabetes Rev 2:375-95. 2006
    ....
  5. ncbi Impaired insulin-stimulated phosphorylation of Akt and AS160 in skeletal muscle of women with polycystic ovary syndrome is reversed by pioglitazone treatment
    Kurt Højlund
    Department of Endocrinology, Odense University Hospital, Kloevervaenget 6, DK 5000 Odense C, Denmark
    Diabetes 57:357-66. 2008
    ..However, the molecular mechanisms underlying skeletal muscle insulin resistance and the insulin-sensitizing effect of thiazolidinediones in PCOS in vivo are less well characterized...
  6. ncbi Energy expenditure, body composition and insulin response to glucose in male twins discordant for the Trp64Arg polymorphism of the beta3-adrenergic receptor gene
    K Højlund
    Diabetes Research Centre, Department of Endocrinology, Odense University Hospital, Odense, Denmark
    Diabetes Obes Metab 8:322-30. 2006
    ..In this, decreased rates of energy expenditure and impaired insulin secretion could play a role...
  7. ncbi Reduced plasma adiponectin concentrations may contribute to impaired insulin activation of glycogen synthase in skeletal muscle of patients with type 2 diabetes
    K Højlund
    Diabetes Research Centre, Department of Endocrinology, Odense University Hospital, Odense, Denmark
    Diabetologia 49:1283-91. 2006
    ..However, the mechanisms by which adiponectin improves insulin sensitivity remain unclear...
  8. ncbi A novel syndrome of autosomal-dominant hyperinsulinemic hypoglycemia linked to a mutation in the human insulin receptor gene
    Kurt Højlund
    Diabetes Research Centre, Department of Endocrinology, Odense University Hospital, Kloevervaenget 6, DK 5000, Odense C, Denmark
    Diabetes 53:1592-8. 2004
    ....
  9. ncbi Effect of insulin on protein phosphatase 2A expression in muscle in type 2 diabetes
    K Højlund
    Department of Endocrinology, Odense University Hospital, Odense C, Denmark
    Eur J Clin Invest 32:918-23. 2002
    ..This study was carried out to investigate the effect of insulin on PP2A expression in skeletal muscles of type 2 diabetic and control subjects...
  10. ncbi Reference intervals for glucose, beta-cell polypeptides, and counterregulatory factors during prolonged fasting
    K Hojlund
    Diabetes Centre, Department of Endocrinology, Odense University Hospital, DK 5000 Odense C, Denmark
    Am J Physiol Endocrinol Metab 280:E50-8. 2001
    ..We observed a diminished beta-cell response concomitant with an increased secretion of counterregulatory hormones. These results should be of clinical and scientific value in the investigation of hypoglycemic disorders...
  11. ncbi Does overnight normalization of plasma glucose by insulin infusion affect assessment of glucose metabolism in Type 2 diabetes?
    P Staehr
    Diabetes Research Centre, Department of Endocrinology M, Odense University Hospital, Kloevervaenget 4 3rd floor, DK 5000 Odense C, Denmark
    Diabet Med 20:816-22. 2003
    ..We assessed whether the choice of either of these methods to obtain euglycaemia biases subsequent assessment of glucose metabolism and insulin action...