J Hannibal

Summary

Affiliation: University of Copenhagen
Country: Denmark

Publications

  1. ncbi request reprint Identification of a major human high molecular weight salivary mucin (MG1) as tracheobronchial mucin MUC5B
    P A Nielsen
    Department of Oral Diagnostics, Faculty of Health Sciences, School of Dentistry, University of Copenhagen, Denmark
    Glycobiology 7:413-9. 1997
  2. ncbi request reprint Expression of melanopsin during development of the rat retina
    Jan Fahrenkrug
    Department of Clinical Biochemistry, Bispebjerg Hospital, DK 2400 Copenhagen NV, Denmark
    Neuroreport 15:781-4. 2004
  3. ncbi request reprint Light and darkness regulate melanopsin in the retinal ganglion cells of the albino Wistar rat
    Jens Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, DK 2400 Copenhagen NV, Denmark
    J Mol Neurosci 27:147-55. 2005
  4. doi request reprint Mice lacking the PACAP type I receptor have impaired photic entrainment and negative masking
    Jens Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, Copenhagen, Denmark
    Am J Physiol Regul Integr Comp Physiol 295:R2050-8. 2008
  5. ncbi request reprint PACAP and glutamate are co-stored in the retinohypothalamic tract
    J Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, Denmark
    J Comp Neurol 418:147-55. 2000
  6. ncbi request reprint Neurotransmitters of the retino-hypothalamic tract
    Jens Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark
    Cell Tissue Res 309:73-88. 2002
  7. ncbi request reprint Melanopsin changes in neonatal albino rat independent of rods and cones
    Jens Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, Copenhagen NV, Denmark
    Neuroreport 18:81-5. 2007
  8. ncbi request reprint Immunoreactive substance P is not part of the retinohypothalamic tract in the rat
    Jens Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, Bispebjerg Bakke 23, DK 2400 Copenhagen NV, Denmark
    Cell Tissue Res 309:293-9. 2002
  9. ncbi request reprint Regulation of melanopsin expression
    Jens Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark
    Chronobiol Int 23:159-66. 2006
  10. ncbi request reprint Pituitary adenylate cyclase-activating peptide in the rat central nervous system: an immunohistochemical and in situ hybridization study
    Jens Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, 2400 Copenhagen NV, Denmark
    J Comp Neurol 453:389-417. 2002

Collaborators

Detail Information

Publications54

  1. ncbi request reprint Identification of a major human high molecular weight salivary mucin (MG1) as tracheobronchial mucin MUC5B
    P A Nielsen
    Department of Oral Diagnostics, Faculty of Health Sciences, School of Dentistry, University of Copenhagen, Denmark
    Glycobiology 7:413-9. 1997
    ..In contrast MUC7 is expressed in serous cells of salivary glands except the parotid glands...
  2. ncbi request reprint Expression of melanopsin during development of the rat retina
    Jan Fahrenkrug
    Department of Clinical Biochemistry, Bispebjerg Hospital, DK 2400 Copenhagen NV, Denmark
    Neuroreport 15:781-4. 2004
    ..The early expression of melanopsin argues for a photoreceptor role in the developing retinohypothalamic tract which is functional as early as the first day after birth...
  3. ncbi request reprint Light and darkness regulate melanopsin in the retinal ganglion cells of the albino Wistar rat
    Jens Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, DK 2400 Copenhagen NV, Denmark
    J Mol Neurosci 27:147-55. 2005
    ..Our observations suggest that the intrinsic light-responsive RGCs adapt their expression of the putative circadian photopigment melanopsin to environmental light and darkness...
  4. doi request reprint Mice lacking the PACAP type I receptor have impaired photic entrainment and negative masking
    Jens Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, Copenhagen, Denmark
    Am J Physiol Regul Integr Comp Physiol 295:R2050-8. 2008
    ..Our findings substantiate a role for PACAP/PAC1 receptor signaling in nonimage-forming vision and indicate that the system is particularly important at lower light intensities...
  5. ncbi request reprint PACAP and glutamate are co-stored in the retinohypothalamic tract
    J Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, Denmark
    J Comp Neurol 418:147-55. 2000
    ..These findings provide an anatomical basis for the recent demonstration of the interaction between these two transmitters on the SCN phase response at night...
  6. ncbi request reprint Neurotransmitters of the retino-hypothalamic tract
    Jens Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark
    Cell Tissue Res 309:73-88. 2002
    ..Possible targets for PACAP and glutamate are the recently identified clock genes Per1 and Per2, which are induced in the SCN by light, glutamate and PACAP at night...
  7. ncbi request reprint Melanopsin changes in neonatal albino rat independent of rods and cones
    Jens Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, Copenhagen NV, Denmark
    Neuroreport 18:81-5. 2007
    ..Our findings indicate that melanopsin protein changes are independent of input from the rods and cones...
  8. ncbi request reprint Immunoreactive substance P is not part of the retinohypothalamic tract in the rat
    Jens Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, Bispebjerg Bakke 23, DK 2400 Copenhagen NV, Denmark
    Cell Tissue Res 309:293-9. 2002
    ....
  9. ncbi request reprint Regulation of melanopsin expression
    Jens Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark
    Chronobiol Int 23:159-66. 2006
    ..These observations show that dual mechanisms regulate melanopsin gene expression and that the intrinsic light-responsive RGCs in the albino Wistar rat adapt their expression of melanopsin to environmental light and darkness...
  10. ncbi request reprint Pituitary adenylate cyclase-activating peptide in the rat central nervous system: an immunohistochemical and in situ hybridization study
    Jens Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, 2400 Copenhagen NV, Denmark
    J Comp Neurol 453:389-417. 2002
    ..The widespread distribution of PACAP in the brain and spinal cord suggests that PACAP is involved in the control of many autonomic and sensory functions as well as higher cortical processes...
  11. ncbi request reprint Melanopsin: a novel photopigment involved in the photoentrainment of the brain's biological clock?
    Jens Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, Denmark
    Ann Med 34:401-7. 2002
    ..Although these findings make melanopsin a strong candidate as a circadian photopigment, a number of functional experiments are needed before the role of melanopsin is finally proven...
  12. ncbi request reprint Neuronal input pathways to the brain's biological clock and their functional significance
    J Hannibal
    Department of Clinical Biochemistry, Bispjebjerg Hospital, Copenhagen, Denmark
    Adv Anat Embryol Cell Biol 182:1-71. 2006
    ....
  13. ncbi request reprint Target areas innervated by PACAP-immunoreactive retinal ganglion cells
    Jens Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark
    Cell Tissue Res 316:99-113. 2004
    ..The findings suggest that PACAP plays a role as neurotransmitter in non-imaging photoperception to target areas in the brain regulating circadian timing, masking, regulation of sleep-wake cycle and pupillary reflex...
  14. ncbi request reprint Melanopsin containing retinal ganglion cells are light responsive from birth
    Jens Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, Bispebjerg Bakke 23, DK 2400 Copenhagen NV, Denmark
    Neuroreport 15:2317-20. 2004
    ..The results indicate that the retina is light responsive before functional rods and cones and that the RHT is functional from birth supporting that photoentrainment of the biological clock begins shortly after birth...
  15. ncbi request reprint The photopigment melanopsin is exclusively present in pituitary adenylate cyclase-activating polypeptide-containing retinal ganglion cells of the retinohypothalamic tract
    Jens Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, DK 2400 Copenhagen, Denmark
    J Neurosci 22:RC191. 2002
    ....
  16. ncbi request reprint PACAP gene expression in neurons of the rat hypothalamo-pituitary-adrenocortical axis is induced by endotoxin and interleukin-1beta
    J Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, Denmark
    Neuroendocrinology 70:73-82. 1999
    ..The findings suggest that PACAP may function as a hypothalamo-pituitary-releasing factor during acute inflammation...
  17. ncbi request reprint Pituitary adenylate cyclase-activating polypeptide in intrinsic and extrinsic nerves of the rat pancreas
    J Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, Denmark
    Cell Tissue Res 299:59-70. 2000
    ..Our data provide a morphological basis for the reported effects of PACAP in the pancreas and suggest that PACAP-containing nerves in the rat pancreas may have both efferent and sensory functions...
  18. ncbi request reprint Dissociation between light-induced phase shift of the circadian rhythm and clock gene expression in mice lacking the pituitary adenylate cyclase activating polypeptide type 1 receptor
    J Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, DK 2400 Copenhagen, Denmark
    J Neurosci 21:4883-90. 2001
    ..These data indicate that PAC1 receptor signaling participates in the gating control of photic sensitivity of the clock and suggest that mPer1, mPer2, and c-fos are of less importance for light-induced phase shifts at night...
  19. ncbi request reprint Melanopsin is expressed in PACAP-containing retinal ganglion cells of the human retinohypothalamic tract
    Jens Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, Denmark
    Invest Ophthalmol Vis Sci 45:4202-9. 2004
    ..Furthermore, whether melanopsin expression is conserved in retinas of blind patients with severe retinal degeneration was investigated...
  20. ncbi request reprint Light-dependent induction of cFos during subjective day and night in PACAP-containing ganglion cells of the retinohypothalamic tract
    J Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, Denmark
    J Biol Rhythms 16:457-70. 2001
    ..Collectively, these data indicate that PACAP is present in ganglion cells that give rise to the RHT and suggest a role for this peptide in the light entrainment of the clock...
  21. ncbi request reprint Pituitary adenylate cyclase activating peptide (PACAP) in the retinohypothalamic tract: a daytime regulator of the biological clock
    J Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, Denmark
    Ann N Y Acad Sci 865:197-206. 1998
    ..Thus, in addition to its role in nocturnal regulation by glutamatergic neurotransmission, the RHT can adjust the biological clock by a PACAP-cAMP-dependent mechanism during the daytime...
  22. ncbi request reprint Serotonin inhibits glutamate- but not PACAP-induced per gene expression in the rat suprachiasmatic nucleus at night
    K M Sanggaard
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, DK 2400 Copenhagen NV, Denmark
    Eur J Neurosci 17:1245-52. 2003
    ..Our findings suggest that the per genes could be the molecular target for the modulatory effects of serotonin on light signalling to the clock...
  23. ncbi request reprint Pituitary adenylate cyclase-activating polypeptide induces period1 and period2 gene expression in the rat suprachiasmatic nucleus during late night
    H S Nielsen
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, DK 2400 NV, Copenhagen, Denmark
    Neuroscience 103:433-41. 2001
    ....
  24. ncbi request reprint Light-induced phase shift in the Syrian hamster (Mesocricetus auratus) is attenuated by the PACAP receptor antagonist PACAP6-38 or PACAP immunoneutralization
    A L Bergström
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, Bispebjerg Bakke 23, DK 2400 Copenhagen NV, Denmark
    Eur J Neurosci 18:2552-62. 2003
    ..The findings indicate that PACAP is a neurotransmitter of the RHT mediating photic information to the clock, possibly via melanopsin located exclusively on the PACAP-expressing cells of the RHT...
  25. ncbi request reprint Pituitary adenylate cyclase activating polypeptide (PACAP) in the gastrointestinal tract of the rat: distribution and effects of capsaicin or denervation
    J Hannibal
    Department of Clinical Biochemistry, University of Copenhagen, Bispebjerg Hospital, Bispebjerg Bakke 23, DK 2400 Copenhagen NV, Denmark
    Cell Tissue Res 291:65-79. 1998
    ..These results indicate that PACAP- immunoreactive nerve fibers in the GI-tract originate from both intrinsic (enteric) and extrinsic (presumably sensory) sources suggesting that PACAP may have diverse gastrointestinal functions...
  26. doi request reprint Neuroglobin expression in the rat suprachiasmatic nucleus: colocalization, innervation, and response to light
    C A Hundahl
    Department of Neuroscience and Pharmacology, Panum Institute, University of Copenhagen, Copenhagen, Denmark
    J Comp Neurol 518:1556-69. 2010
    ..The results indicate that the Ngb could be involved in both photic and nonphotic entrainment via input from the GHT...
  27. ncbi request reprint Homer-1 mRNA in the rat suprachiasmatic nucleus is regulated differentially by the retinohypothalamic tract transmitters pituitary adenylate cyclase activating polypeptide and glutamate at time points where light phase-shifts the endogenous rhythm
    Henriette S Nielsen
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, DK 2400 Copenhagen NV, Denmark
    Brain Res Mol Brain Res 105:79-85. 2002
    ..In conclusion, the RHT transmitters PACAP and glutamate could be responsible for the light-induced expression of Homer-1 in the SCN, and Homer-1 seems to be differentially regulated by the two transmitters at early and late night...
  28. doi request reprint Diurnal rhythmicity of the canonical clock genes Per1, Per2 and Bmal1 in the rat adrenal gland is unaltered after hypophysectomy
    J Fahrenkrug
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark
    J Neuroendocrinol 20:323-9. 2008
    ....
  29. ncbi request reprint PACAP 1-38 as neurotransmitter in the porcine antrum
    K Tornøe
    Department of Medical Physiology, The Panum Institute, University of Copenhagen, Blegdamsvej 3, DK 2200, N, Copenhagen, Denmark
    Regul Pept 101:109-21. 2001
    ..Conclusion: PACAP 1-38 may be involved in antral motility and secretion by interacting with cholinergic, SP-ergic, GRP-ergic and/or VIP-ergic neurones, and may also be involved in afferent reflex pathways...
  30. ncbi request reprint Vasoactive intestinal polypeptide induces per1 and per2 gene expression in the rat suprachiasmatic nucleus late at night
    Henriette S Nielsen
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, DK 2400, Copenhagen NV, Denmark
    Eur J Neurosci 15:570-4. 2002
    ..Our results demonstrate that both pathways are involved in VIP induced per gene expression and suggest that VIP is important for light-induced phase shift late at night...
  31. doi request reprint Restricted expression of Neuroglobin in the mouse retina and co-localization with Melanopsin and Tyrosine Hydroxylase
    C A Hundahl
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark
    Biochem Biophys Res Commun 425:100-6. 2012
    ..The present study suggests that a number of previously published reports have relied on antibodies with dubious specificity...
  32. ncbi request reprint Innervation of the rat pineal gland by pituitary adenylate cyclase-activating polypeptide (PACAP)-immunoreactive nerve fibres
    M Møller
    Institute of Medical Anatomy, Panum Institute, Copenhagen, Denmark
    Cell Tissue Res 296:247-57. 1999
    ..The colocalization of PACAP with calcitonin gene-related peptide in the pincalopetal nerve fibres indicates that the majority of PACAP-immunoreactive nerve fibres might originate from the trigeminal ganglion...
  33. ncbi request reprint Roles of PACAP-containing retinal ganglion cells in circadian timing
    Jens Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, Denmark
    Int Rev Cytol 251:1-39. 2006
    ....
  34. ncbi request reprint Photic induction of c-Fos in enkephalin neurons of the rat intergeniculate leaflet innervated by retinal PACAP fibres
    Fie Juhl
    Department of Clinical Biochemistry, Bispebjerg University Hospital, DK 2400 Copenhagen NV, Denmark
    Cell Tissue Res 329:491-502. 2007
    ....
  35. ncbi request reprint Synaptic contact between melanopsin-containing retinal ganglion cells and rod bipolar cells
    Jens Østergaard
    Departments of Ophthalmology, Rigshospitalet, Copenhagen, Denmark
    Invest Ophthalmol Vis Sci 48:3812-20. 2007
    ..This study was performed to identify retinal cells that have synaptic contact with ipRGCs...
  36. ncbi request reprint Lack of the PAC1 receptor alters the circadian expression of VIP mRNA in the suprachiasmatic nucleus of mice
    Birgitte Georg
    Department of Clinical Biochemistry, Bispebjerg University Hospital, DK 2400 Copenhagen NV, Denmark
    Brain Res 1135:52-7. 2007
    ..The results show that the circadian VIP mRNA expression is influenced by the absence of PAC1 signalling...
  37. ncbi request reprint Neurotransmitters co-existing with VIP or PACAP
    Jan Fahrenkrug
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, DK 2400 Copenhagen NV, Denmark
    Peptides 25:393-401. 2004
    ..The present paper deals with transmitter substances, peptides or classical transmitters, co-existing with the two structurally related peptides VIP and PACAP and the possible functional implications of this co-existence...
  38. doi request reprint Vesicular glutamate transporter 2 (VGLUT2) is co-stored with PACAP in projections from the rat melanopsin-containing retinal ganglion cells
    Anna Engelund
    Department of Clinical Biochemistry, Bispebjerg Hospital, Faculty of Health Sciences, University of Copenhagen, Bispebjerg Bakke 23, DK 2400, Copenhagen, Denmark
    Cell Tissue Res 340:243-55. 2010
    ..Furthermore, we conclude that VGLUT2 is the preferred subtype of vesicular transporter used by these cells...
  39. ncbi request reprint Decreased VIP and VPAC2 receptor expression in the biological clock of the R6/2 Huntington's disease mouse
    Jan Fahrenkrug
    Department of Clinical Biochemistry, Bispebjerg University Hospital, Copenhagen NV, Denmark
    J Mol Neurosci 31:139-48. 2007
    ..In conclusion, we propose that impaired VIPergic signaling is an additional candidate mechanism for disruption of circadian rhythms in R6/2 mice...
  40. ncbi request reprint The circadian photopigment melanopsin is expressed in the blind subterranean mole rat, Spalax
    Jens Hannibal
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Bispebjerg Bakke 23, DK 2400 Copenhagen NV, Denmark
    Neuroreport 13:1411-4. 2002
    ..The results show that the Spalax, as sighted animals expresses melanopsin in ganglion cells projecting to the circadian clock supporting a role of melanopsin as a circadian photopigment...
  41. ncbi request reprint Diurnal rhythmicity of the clock genes Per1 and Per2 in the rat ovary
    Jan Fahrenkrug
    Department of Clinical Biochemistry, Bispebjerg Hospital, DK 2400 Copenhagen NV, Denmark
    Endocrinology 147:3769-76. 2006
    ..These findings suggest the existence of an ovarian circadian clock, which may play a role both locally and in the hypothalamo-pituitary-ovarian axis...
  42. ncbi request reprint Altered calmodulin response to light in the suprachiasmatic nucleus of PAC1 receptor knockout mice revealed by proteomic analysis
    Jan Fahrenkrug
    Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, DK 2400 Copenhagen NV, Denmark
    J Mol Neurosci 25:251-8. 2005
    ..The findings indicate that PAC1 receptor signaling in the SCN in response to light stimulation induces a down-regulation of CaM expression and that CaM is involved in the photic-entrainment mechanism...
  43. ncbi request reprint VIP and PACAP display different vasodilatory effects in rabbit coronary and cerebral arteries
    Torur Dalsgaard
    Department of Obstetrics and Gynaecology 537, Hvidovre University Hospital, Kettegard Alle 30, DK 2650 Hvidovre, Copenhagen, Denmark
    Regul Pept 110:179-88. 2003
    ..Treatment with female sex steroids does not seem to change these mechanisms...
  44. ncbi request reprint Endothelial and lipoprotein lipases in human and mouse placenta
    Marie L S Lindegaard
    Department of Clinical Biochemistry, Rigshospitalet, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark
    J Lipid Res 46:2339-46. 2005
    ..Nevertheless, the two lipases might have overlapping functions in the mouse placenta. Our data also suggest that the major portions of both proteins are stored in an inactive form in human term placenta...
  45. doi request reprint Anatomical characterization of cytoglobin and neuroglobin mRNA and protein expression in the mouse brain
    Christian Ansgar Hundahl
    Department of Neuroscience and Pharmacology, The Panum Institute, University of Copenhagen, Copenhagen, Denmark
    Brain Res 1331:58-73. 2010
    ..We believe other functions than pure oxygen buffers and neuroprotectants should be considered. The anatomical data indicate a role in NO signalling for Cygb and involvement in sleep-wake cycling for Cygb and Ngb...
  46. ncbi request reprint Expression of the endothelial lipase gene in murine embryos and reproductive organs
    Marie L S Lindegaard
    Department of Clinical Biochemistry, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    J Lipid Res 46:439-44. 2005
    ..These results suggest that EL, in addition to its effects on plasma lipoprotein metabolism, plays a role in murine reproduction...
  47. pmc The cell-specific pattern of cholecystokinin peptides in endocrine cells versus neurons is governed by the expression of prohormone convertases 1/3, 2, and 5/6
    Jens F Rehfeld
    Department of Clinical Biochemistry, Rigshospitalet, Blegdamsvej 9, Copenhagen, Denmark
    Endocrinology 149:1600-8. 2008
    ..The results suggest that the different peptide patterns in the brain and the gut are due to different expression of PCs...
  48. ncbi request reprint Circadian rhythm regulation: a central role for the neuropeptide vasoactive intestinal polypeptide
    Jens Hannibal
    Am J Physiol Regul Integr Comp Physiol 285:R935-6. 2003
  49. ncbi request reprint Distribution and regional variation of pituitary adenylate cyclase activating polypeptide and other neuropeptides in the rat urinary bladder and ureter: effects of age
    Hamid Mohammed
    School of Biosciences, University of Wales, Cardiff, PO Box 911, Cardiff CF10 3US, United Kingdom
    Urol Res 30:248-55. 2002
    ..These findings suggest that the level of sensory innervation of the bladder and distal ureter are reduced in old age and that the afferent limb of voiding reflexes may in consequence be perturbed...
  50. ncbi request reprint Characterization and synaptic connectivity of melanopsin-containing ganglion cells in the primate retina
    Patricia R Jusuf
    National Vision Research Institute of Australia, Cnr Keppel and Cardigan Streets, Carlton, Victoria 3053, Australia
    Eur J Neurosci 26:2906-21. 2007
    ..Our results are consistent with the idea that both outer and inner melanopsin cells receive bipolar and amacrine input across their dendritic tree...
  51. doi request reprint Distribution of Wfs1 protein in the central nervous system of the mouse and its relation to clinical symptoms of the Wolfram syndrome
    Hendrik Luuk
    Department of Physiology, University of Tartu, Tartu 50411, Estonia
    J Comp Neurol 509:642-60. 2008
    ..Enrichment of Wfs1 protein in the central extended amygdala suggests a role in the modulation of anxiety and fear...
  52. ncbi request reprint Immunocytochemical distribution of VIP and PACAP in the rat brain stem: implications for REM sleep physiology
    Abdel Ahnaou
    Stanford University, Department of Biological Sciences, 371 Serra Mall, Stanford, CA 94305 5020, USA
    Ann N Y Acad Sci 1070:135-42. 2006
    ..The present results provide an anatomical basis to our previous functional data, and suggest that PACAPergic mechanisms within the PRF play a critical role in long-term regulation of REMS...
  53. ncbi request reprint Presence of pituitary adenylate cyclase-activating polypeptide (PACAP) defines a subpopulation of hypothalamic POMC neurons
    Katrin Durr
    Department of Neuroscience, Retzius vag 8, Karolinska Institutet, Stockholm, Sweden
    Brain Res 1186:203-11. 2007
    ..The results show presence of PACAP with alpha-MSH in a subpopulation of hypothalamic POMC neurons and point further to the neurochemical heterogeneity of hypothalamic, but not brainstem, POMC neurons...
  54. ncbi request reprint [A newly discovered photopigment in the retina, melanopsin, directs the biological clocks of the brain]
    Jens Hannibal
    Bispebjerg Hospital, Klinisk Biokemisk Afdeling, Københavns Universitet, Panum Instituttet, Medicinsk Fysiologisk Institut
    Ugeskr Laeger 164:2523. 2002