- Grimm D, Infanger M, Westphal K, Ulbrich C, Pietsch J, Kossmehl P, et al. A delayed type of three-dimensional growth of human endothelial cells under simulated weightlessness. Tissue Eng Part A. 2009;15:2267-75 pubmed publisher..These results suggest that culturing ECs under conditions of modeled gravitational unloading represents a new technique for studying the formation of tubes that resemble vascular intimas. ..
- Grimm D, Bauer J, Ulbrich C, Westphal K, Wehland M, Infanger M, et al. Different responsiveness of endothelial cells to vascular endothelial growth factor and basic fibroblast growth factor added to culture media under gravity and simulated microgravity. Tissue Eng Part A. 2010;16:1559-73 pubmed publisher..These findings provide evidence that phosphokinase Calpha plays a key role in tube formation. Improving the interaction of VEGF and/or bFGF with EC under s-microg could enhance the engineering of vascular intimas. ..