Research Topics
Species | Henrik FrederiksenSummaryAffiliation: University of Southern Denmark Country: Denmark Publications
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Detail Information
Publications
Do children of long-lived parents age more successfully?Henrik Frederiksen
Institute of Public Health, Epidemiology, University of Southern Denmark, Odense
Epidemiology 13:334-9. 2002..Long-lived individuals are rare and may be selected in part for the genetic factors that promote successful aging. The children of long-lived parents may therefore age more successfully than the children of short-lived parents...- Hand grip strength: a phenotype suitable for identifying genetic variants affecting mid- and late-life physical functioningHenrik Frederiksen
Danish Twin Registry, Epidemiology Unit, University of Southern Denmark, Odense, Denmark
Genet Epidemiol 23:110-22. 2002..Hence grip strength is a suitable phenotype for identifying genetic variants of importance to mid- and late-life physical functioning... - [Do children of long-lived parents age more successfully?]Henrik Frederiksen
Institut for Sundhedstjenesteforskning, Epidemiologi, Syddansk Universitet, 5000 Odense C
Ugeskr Laeger 164:5027-32. 2002..Long-lived individuals are rare and may be selected in part for the genetic factors that promote successful ageing. The children of long-lived parents may therefore age more successfully than the children of short-lived parents... - Age trajectories of grip strength: cross-sectional and longitudinal data among 8,342 Danes aged 46 to 102Henrik Frederiksen
Epidemiology, Institute of Public Health, University of Southern Denmark, Odense, Denmark
Ann Epidemiol 16:554-62. 2006..The purpose is to study the age trajectory of hand-grip strength after the age of 45 years... - ACE genotype and physical training effects: a randomized study among elderly DanesHenrik Frederiksen
Institute of Public Health, Epidemiology, University of Southern Denmark, Odense, Denmark
Aging Clin Exp Res 15:284-91. 2003..However, ACE studies have mainly been conducted among younger persons in excellent physical shape. In this study, we examine whether the level of PF, trainability, or rate-of-change are associated with the ACE genotype among the elderly... - Genetic and environmental contributions to back pain in old age: a study of 2,108 danish twins aged 70 and olderJan Hartvigsen
Nordic Institute of Chiropractic and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark
Spine (Phila Pa 1976) 29:897-901; discussion 902. 2004..Self-reported 1-month prevalence of back pain in older twins assessed at intake in a population-based longitudinal survey... - The catalase -262C/T promoter polymorphism and aging phenotypesLene Christiansen
Epidemiology, Institute of Public Health, University of Southern Denmark
J Gerontol A Biol Sci Med Sci 59:B886-9. 2004..The results raise the hypothesis that the catalase -262T allele serves as protection against neurodegenerative and physical decline, although replication in other studies is warranted for confirmation of these findings... - ["Looking your age"--genetics and mortality]Kaare Christensen
Syddansk Universitet, Institut for Sundhedstjenesteforskning, Det Danske Tvillingregister, Epidemiologi
Ugeskr Laeger 166:3500-1. 2004 - Self-rated health and age: a cross-sectional and longitudinal study of 11,000 Danes aged 45-102Frank Krarup Andersen
Epidemiology, Institute of Public Health, University of Southern Denmark, Odense C, Denmark
Scand J Public Health 35:164-71. 2007..The aim of this study was to explore and describe self-rated health in middle-aged and elderly Danes using both a cross-sectional and a longitudinal design. Global and (age) comparative self-rated health are examined and compared... - Angiotensin I-converting enzyme (ACE) gene polymorphism in relation to physical performance, cognition and survival--a follow-up study of elderly Danish twinsHenrik Frederiksen
Department of Epidemiology, Institute of Public Health, University of Southern Denmark, Main Campus Odense University, Odense, Denmark
Ann Epidemiol 13:57-65. 2003..Using a longitudinal study of elderly twins we studied the association between ACE genotype and physical and cognitive functioning and survival in old age... - Back and neck pain exhibit many common features in old age: a population-based study of 4,486 Danish twins 70-102 years of ageJan Hartvigsen
Nordic Institute of Chiropractic and Clinical Biomechanics, Institute of Public Health, University of Southern Denmark, Odense C, Denmark
Spine (Phila Pa 1976) 29:576-80. 2004..Cross-sectional and longitudinal analysis of data comprising 4486 Danish twins 70-102 years of age... - Age trajectories of genetic variance in physical functioning: a longitudinal study of Danish twins aged 70 years and olderKaare Christensen
The Danish Twin Registry, Epidemiology, Institute of Public Health, University of Southern Denmark, DK 5000 Odense, Denmark
Behav Genet 33:125-36. 2003.... - Physical and mental function and incident low back pain in seniors: a population-based two-year prospective study of 1387 Danish Twins aged 70 to 100 yearsJan Hartvigsen
Nordic Institute of Chiropractic and Clinical Biomechanics, Clinical Locomotion Science, Odense, Denmark
Spine (Phila Pa 1976) 31:1628-32. 2006..Prospective cohort study... - Genetic dissection of gene expression observed in whole blood samples of elderly Danish twinsQihua Tan
Department of Clinical Biochemistry and Genetics (KKA, Odense University Hospital, Sdr. Boulevard 29, 5000 Odense C, Denmark
Hum Genet 117:267-74. 2005..In conclusion, the correlation patterns revealed in our twin data provide evidence of the existence of a heritable mechanism in gene expression regulation persistently functioning even in aged subjects... - Age- and sex-differences in the validity of questionnaire-based zygosity in twinsLene Christiansen
The Danish Twin Registry, Institute of Public Health, University of Southern Denmark, Odense, Denmark
Twin Res 6:275-8. 2003..The results demonstrate that questionnaire based zygosity diagnosis can still be regarded as a valid and valuable classification method for most purposes... - Use of proton pump inhibitors and the risk of community-acquired pneumonia: a population-based case-control studySinem Ezgi Gulmez
Research Unit of Clinical Pharmacology, Faculty of Health Sciences, Institute of Public Health, University of Southern Denmark, Odense, Denmark
Arch Intern Med 167:950-5. 2007..Recently, the use of proton pump inhibitors (PPIs) has been associated with an increased risk of pneumonia. We aimed to confirm this association and to identify the risk factors... - Possible associations between successful aging and polymorphic markers in the Werner gene regionMari Sild
Institute of Human Genetics, University of Aarhus, Denmark
Ann N Y Acad Sci 1067:309-10. 2006..We found certain close-set SNPs in the 5' flanking region and 5' UTR to be significantly associated with the cognitive functioning level in old age... 
Back and neck pain in seniors-prevalence and impactJan Hartvigsen
Nordic Institute of Chiropractic and Clinical Biomechanics, Research, Odense C, Denmark
Eur Spine J 15:802-6. 2006..NP and BP in seniors are probably associated with difficulty but not inability to perform daily activities...- Small effect of genetic factors on neck pain in old age: a study of 2,108 Danish twins 70 years of age and olderJan Hartvigsen
Nordic Institute of Chiropractic and Clinical Biomechanics, Odense C, Denmark
Spine (Phila Pa 1976) 30:206-8. 2005..Classic twin study... - A polymorphic marker in the first intron of the Werner gene associates with cognitive function in aged Danish twinsMette H Bendixen
Institute of Human Genetics, University of Aarhus, C, Denmark
Exp Gerontol 39:1101-7. 2004..However, since the t-allele of this SNP is very rare, we did not encounter any tt-homozygous individuals for this allele... - Association between low self-rated health and heterozygosity for -110A > C polymorphism in the promoter region of HSP70-1 in aged Danish twinsRipudaman Singh
Department of Human Genetics, University of Aarhus, DK 8000, Aarhus C, Denmark
Biogerontology 5:169-76. 2004..An association was found between low self-rated health and heterozygosity for -110A > C polymorphism in the promoter region of HSP70-1 in aged Danish twins... - "Looking old for your age": genetics and mortalityKaare Christensen
Epidemiology 15:251-2. 2004 - Back pain remains a common symptom in old age. a population-based study of 4486 Danish twins aged 70-102Jan Hartvigsen
Nordic Institute of Chiropractic and Clinical Biomechanics, Klosterbakken 20, 5000, Odense C, Denmark
Eur Spine J 12:528-34. 2003..We conclude that BP is a common symptom in old age; however, the prevalence does not change with increasing age. BP may be part of a more general syndrome of poor health among the old... - Incidence of idiopathic thrombocytopenic purpura among adultsHenrik Frederiksen
Br J Haematol 125:90; author reply 90-1. 2004 
Evaluation of a screening instrument for essential tremorDelia Lorenz
Department of Neurology, Christian Albrechts University Kiel, Germany
Mov Disord 23:1006-12. 2008..We present an easy to use and reliable screening instrument that is effective to identify patients with ET but not able to exclude patients with other tremor forms...