Kevin A Francesconi

Summary

Affiliation: University of Southern Denmark
Country: Denmark

Publications

  1. ncbi request reprint Arsenic metabolites in human urine after ingestion of an arsenosugar
    Kevin A Francesconi
    Institute of Biology, University of Southern Denmark, 5230 Odense M, Denmark
    Clin Chem 48:92-101. 2002
  2. ncbi request reprint Arsenic species in an arsenic hyperaccumulating fern, Pityrogramma calomelanos: a potential phytoremediator of arsenic-contaminated soils
    Kevin Francesconi
    Institute of Biology, University of Southern Denmark, Odense
    Sci Total Environ 284:27-35. 2002
  3. ncbi request reprint Biotransformation of arsenate to the tetramethylarsonium ion in the marine polychaetes Nereis diversicolor and Nereis virens
    Anita E Geiszinger
    Biology Institute, University of Southern Denmark, Odense
    Environ Sci Technol 36:2905-10. 2002
  4. ncbi request reprint Determination of arsenic species: a critical review of methods and applications, 2000-2003
    Kevin A Francesconi
    Institute of Chemistry Analytical Chemistry, Karl Franzens University, Universitaetsplatz 1, 8010 Graz, Austria
    Analyst 129:373-95. 2004
  5. ncbi request reprint The marine polychaete Arenicola marina: its unusual arsenic compound pattern and its uptake of arsenate from seawater
    Anita E Geiszinger
    Biology Institute, University of Southern Denmark, DK 5230 Odense M, Denmark
    Mar Environ Res 53:37-50. 2002
  6. ncbi request reprint Uptake and elimination of arsenobetaine by the mussel Mytilus edulis is related to salinity
    Lone Andreasen Clowes
    Institute of Biology, University of Southern Denmark, 5230 Odense M, Denmark
    Comp Biochem Physiol C Toxicol Pharmacol 137:35-42. 2004
  7. ncbi request reprint Direct measurement of lipid-soluble arsenic species in biological samples with HPLC-ICPMS
    Ernst Schmeisser
    Karl Franzens University Graz, Institute of Chemistry Analytical Chemistry, Universitaetsplatz 1, 8010 Graz, Austria
    Analyst 130:948-55. 2005
  8. ncbi request reprint Application of selected reaction monitoring tandem mass spectrometry to the quantitative determination of an arsenic-containing nucleoside in a crude biological extract
    Kevin A Francesconi
    University of Crete, Department of Chemistry, Environmental Chemical Processes Laboratory, Heraklion, Greece
    Analyst 129:398-9. 2004
  9. ncbi request reprint Volatile analytes formed from arsenosugars: determination by HPLC-HG-ICPMS and implications for arsenic speciation analyses
    Ernst Schmeisser
    Institute of Chemistry, Analytical Chemistry, Karl Franzens University, Universitaetsplatz 1, 8010 Graz, Austria
    Anal Chem 76:418-23. 2004
  10. ncbi request reprint Selenium metabolites in urine of cancer patients receiving L-selenomethionine at high doses
    Doris Kuehnelt
    Institute of Chemistry Analytical Chemistry, Karl Franzens University Graz, Universitaetsplatz 1, 8010 Graz, Austria
    Toxicol Appl Pharmacol 220:211-5. 2007

Collaborators

Detail Information

Publications27

  1. ncbi request reprint Arsenic metabolites in human urine after ingestion of an arsenosugar
    Kevin A Francesconi
    Institute of Biology, University of Southern Denmark, 5230 Odense M, Denmark
    Clin Chem 48:92-101. 2002
    ..Arsenic-containing carbohydrates (arsenosugars) are common constituents of marine algae, including those species used as human food. The toxicology of these compounds has not been fully evaluated...
  2. ncbi request reprint Arsenic species in an arsenic hyperaccumulating fern, Pityrogramma calomelanos: a potential phytoremediator of arsenic-contaminated soils
    Kevin Francesconi
    Institute of Biology, University of Southern Denmark, Odense
    Sci Total Environ 284:27-35. 2002
    ..With due consideration to the type of arsenic compounds present in the fern, and their water-solubility, the option of disposing high arsenic ferns at sea is raised for discussion...
  3. ncbi request reprint Biotransformation of arsenate to the tetramethylarsonium ion in the marine polychaetes Nereis diversicolor and Nereis virens
    Anita E Geiszinger
    Biology Institute, University of Southern Denmark, Odense
    Environ Sci Technol 36:2905-10. 2002
    ..This is the first report of significant biomethylation of arsenic to the tetramethyl stage and provides a ready explanation for the widespread occurrence of tetramethylarsonium ion in marine animals...
  4. ncbi request reprint Determination of arsenic species: a critical review of methods and applications, 2000-2003
    Kevin A Francesconi
    Institute of Chemistry Analytical Chemistry, Karl Franzens University, Universitaetsplatz 1, 8010 Graz, Austria
    Analyst 129:373-95. 2004
    ..We review recent research in the field of arsenic speciation analysis with the emphasis on significant advances, novel applications and current uncertainties...
  5. ncbi request reprint The marine polychaete Arenicola marina: its unusual arsenic compound pattern and its uptake of arsenate from seawater
    Anita E Geiszinger
    Biology Institute, University of Southern Denmark, DK 5230 Odense M, Denmark
    Mar Environ Res 53:37-50. 2002
    ..with the remainder being accumulated as unchanged arsenate. None of the other arsenic compounds naturally present in A. marina increased in concentration following arsenate exposure...
  6. ncbi request reprint Uptake and elimination of arsenobetaine by the mussel Mytilus edulis is related to salinity
    Lone Andreasen Clowes
    Institute of Biology, University of Southern Denmark, 5230 Odense M, Denmark
    Comp Biochem Physiol C Toxicol Pharmacol 137:35-42. 2004
    ..The data are consistent with a proposed role of arsenobetaine as an adventitiously acquired osmolyte, and readily explain field data for freshwater and marine animals...
  7. ncbi request reprint Direct measurement of lipid-soluble arsenic species in biological samples with HPLC-ICPMS
    Ernst Schmeisser
    Karl Franzens University Graz, Institute of Chemistry Analytical Chemistry, Universitaetsplatz 1, 8010 Graz, Austria
    Analyst 130:948-55. 2005
    ....
  8. ncbi request reprint Application of selected reaction monitoring tandem mass spectrometry to the quantitative determination of an arsenic-containing nucleoside in a crude biological extract
    Kevin A Francesconi
    University of Crete, Department of Chemistry, Environmental Chemical Processes Laboratory, Heraklion, Greece
    Analyst 129:398-9. 2004
    ..20 microg As l(-1)) in a crude extract of kidney from the clam Tridacna derasa...
  9. ncbi request reprint Volatile analytes formed from arsenosugars: determination by HPLC-HG-ICPMS and implications for arsenic speciation analyses
    Ernst Schmeisser
    Institute of Chemistry, Analytical Chemistry, Karl Franzens University, Universitaetsplatz 1, 8010 Graz, Austria
    Anal Chem 76:418-23. 2004
    ....
  10. ncbi request reprint Selenium metabolites in urine of cancer patients receiving L-selenomethionine at high doses
    Doris Kuehnelt
    Institute of Chemistry Analytical Chemistry, Karl Franzens University Graz, Universitaetsplatz 1, 8010 Graz, Austria
    Toxicol Appl Pharmacol 220:211-5. 2007
    ..These data refute the currently accepted role of TMSe as the preferred excretion metabolite when selenium exposure is high...
  11. doi request reprint Arsenic speciation in plants growing in arsenic-contaminated sites
    Maria José Ruiz-Chancho
    Departament de Quimica Analitica, Universitat de Barcelona, Marti i Franques 1 11, 08028 Barcelona, Spain
    Chemosphere 71:1522-30. 2008
    ..In the present study, the patterns of arsenic species varied with the plant species and much higher proportion of organoarsenicals was found in plants from the more contaminated sites...
  12. ncbi request reprint Thio-dimethylarsinate is a common metabolite in urine samples from arsenic-exposed women in Bangladesh
    Reingard Raml
    Karl Franzens University Graz, Institute of Chemistry Analytical Chemistry, Universitaetsplatz 1, 8010 Graz, Austria
    Toxicol Appl Pharmacol 222:374-80. 2007
    ..The work highlights the need for analytical methods providing specific determinations of arsenic compounds in future studies on arsenic metabolism and toxicology...
  13. ncbi request reprint Determination of selenosugars in crude human urine using high-performance liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry
    Sophia Letsiou
    University of Crete, Department of Chemistry, Environmental Chemical Processes Laboratory, Voutes, Heraklion 71003, Crete, Greece
    Rapid Commun Mass Spectrom 21:343-51. 2007
    ..Additionally, SeGalNH2 was detected in urine samples after Se supplementation. Finally, neutral loss scanning was explored as a possible method for the detection of unknown methyl-selenosugars...
  14. ncbi request reprint Toxic metal species and food regulations--making a healthy choice
    Kevin A Francesconi
    Institute of Chemistry Analytical Chemistry, Karl Franzens University Graz, 8010 Graz, Austria
    Analyst 132:17-20. 2007
    ..Some practical aspects and implications of framing food legislation in terms of metal species are presented...
  15. ncbi request reprint Consequences of vapor enhancement on selenium speciation analysis by HPLC/ICPMS
    Dijana Juresa
    Institute of Chemistry Analytical Chemistry, Karl Franzens University Graz, Universitaetsplatz 1, 8010 Graz, Austria
    Anal Chem 78:8569-74. 2006
    ..In addition, it raises broader issues of the validity of the "dilute and shoot" approach to the determination of metals in clinical analysis of biological fluids...
  16. ncbi request reprint Marked individual variability in the levels of trimethylselenonium ion in human urine determined by HPLC/ICPMS and HPLC/vapor generation/ICPMS
    Doris Kuehnelt
    Division of Analytical Chemistry, Institute of Chemistry, Karl Franzens University Graz, Universitatsplatz 1, 8010, Graz, Austria
    Anal Bioanal Chem 386:2207-12. 2006
    ..This marked individual variability in the formation of TMSe was maintained in a duplicate investigation of urine from the same seven volunteers...
  17. ncbi request reprint Improved chromatographic separation of thio-arsenic compounds by reversed-phase high performance liquid chromatography-inductively coupled plasma mass spectrometry
    Reingard Raml
    Karl Franzens University Graz, Institute of Chemistry Analytical Chemistry, Universitaetsplatz 1, 8010 Graz, Austria
    J Chromatogr A 1128:164-70. 2006
    ..6 microg As/L based on 10 microL injection volume. Further, we have applied the method to the identification and quantification of thio-arsenic species in two standard reference materials, BCR 710 oyster tissue and NIES 18 human urine...
  18. ncbi request reprint Accumulation and elimination of dietary arsenobetaine in two species of fish, Atlantic salmon (Salmo salar L.) and Atlantic cod (Gadus morhua L.)
    Heidi Amlund
    National Institute of Nutrition and Seafood Research, P O Box 2029 Nordnes, 5817 Bergen, Norway
    Environ Toxicol Chem 25:1787-94. 2006
    ..The differences in arsenobetaine disposition studied in Atlantic salmon and Atlantic cod contribute to explain the differences in arsenic levels observed among marine fish...
  19. ncbi request reprint Human metabolism of arsenolipids present in cod liver
    Ernst Schmeisser
    Institute of Chemistry Analytical Chemistry, Karl Franzens University Graz, Universitaetsplatz 1, 8010, Graz, Austria
    Anal Bioanal Chem 385:367-76. 2006
    ....
  20. ncbi request reprint Arsenic fatty acids are human urinary metabolites of arsenolipids present in cod liver
    Ernst Schmeisser
    Institute of Chemistry Analytical Chemistry, Karl Franzens University Graz, Universitatsplatz 1, 8010 Graz, Austria
    Angew Chem Int Ed Engl 45:150-4. 2005
  21. ncbi request reprint Arsenic speciation in farmed Hungarian freshwater fish
    Csilla Soeroes
    Department of Applied Chemistry, Faculty of Food Science, Bkáe University, Villányi út 29 33, 1118 Budapest, Hungary
    J Agric Food Chem 53:9238-43. 2005
    ..The contrast between these two freshwater aquaculture species regarding total arsenic and arsenic species has relevant toxicological aspects in terms of food safety...
  22. ncbi request reprint Novel thioarsenic metabolites in human urine after ingestion of an arsenosugar, 2',3'-dihydroxypropyl 5-deoxy-5-dimethylarsinoyl-beta-D-riboside
    Reingard Raml
    Institute of Chemistry Analytical Chemistry, Karl Franzens University Graz, Austria
    Chem Res Toxicol 18:1444-50. 2005
    ..Cytotoxicity testing of the major metabolites DMA, oxo-DMAE, thio-DMAE, oxo-DMAA, and thio-DMAA showed that they were nontoxic even at 10 mM, except for DMA, which showed some toxic effects at 1 mM...
  23. ncbi request reprint Thio arsenosugars in freshwater mussels from the Danube in Hungary
    Csilla Soeroes
    Department of Applied Chemistry, Faculty of Food Science, Corvinus University, Villányi út 29 33, 1118 Budapest, Hungary
    J Environ Monit 7:688-92. 2005
    ..This is the first report of thio arsenosugars in freshwater biota and suggests that these compounds may be common and widespread naturally-occurring arsenicals...
  24. ncbi request reprint Speciation analysis with HPLC-mass spectrometry: time to take stock
    Kevin A Francesconi
    Institute of Chemistry Analytical Chemistry, Karl Franzens University Graz, Universitaetsplatz 1, 8010, Graz, Austria
    Analyst 130:998-1001. 2005
  25. ncbi request reprint Nitrogen purity influences the occurrence of As+ ions in high-performance liquid chromatography/electrospray ionization mass spectrometric analysis of four common arsenosugars
    Doris Kuehnelt
    Institute of Chemistry, Analytical Chemistry, Karl Franzens University, Universitaetsplatz 1, 8010 Graz, Austria
    Rapid Commun Mass Spectrom 17:654-9. 2003
    ..Molecular and elemental information from one chromatographic run is a valuable tool for the characterization of unknown arsenic compounds...
  26. ncbi request reprint Arsenic-containing long-chain fatty acids in cod-liver oil: a result of biosynthetic infidelity?
    Alice Rumpler
    Institute of Chemistry Analytical Chemistry, Karl Franzens University Graz, Universitaetsplatz 1, 8010 Graz, Austria
    Angew Chem Int Ed Engl 47:2665-7. 2008