Research Topics
| T EngstrømSummaryAffiliation: University of Copenhagen Country: Denmark Publications
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Detail Information
Publications
Oxytocin receptor binding and uterotonic activity of carbetocin and its metabolites following enzymatic degradationT Engstrøm
Department of Medical Physiology, The Panum Institute, University of Copenhagen, Denmark
Eur J Pharmacol 355:203-10. 1998..7 +/- 7.34 nM compared to 7.24 +/- 0.29 nM for carbetocin and 9.89 + 2.80 nM for carbetocin metabolite I. Only carbetocin bound to the renal vasopressin V2 receptor though the binding affinity was very low (61.3 +/- 14.6 nM)...
Effect of oxytocin receptor and beta2-adrenoceptor blockade on myometrial oxytocin receptors in parturient ratsT Engstrøm
Department of Internal Medicine and Endocrinology, Herlev Hospital, University of Copenhagen, 2730 Herlev, Denmark
Biol Reprod 60:322-9. 1999..The OTR down-regulation seen after atosiban treatment adds to the direct relaxing effect of atosiban on the myometrium. In view of this, atosiban may prove to be a more useful tocolytic than the traditionally used beta2 agonists...
Effect of oxytocin receptor blockade on rat myometrial responsiveness to prostaglandin f(2)(alpha)T Engstrøm
Department of Internal Medicine and Endocrinology, Herlev Hospital, University of Copenhagen, Denmark
Biol Reprod 63:1443-9. 2000..In this context PGF(2alpha) receptor stimulation may, in the absence of oxytocin receptor stimulation, exert the contractile forces needed for proper propulsion of the fetus...
The regulation by ovarian steroids of prostaglandin synthesis and prostaglandin-induced contractility in non-pregnant rat myometrium. Modulating effects of isoproterenolT Engstrøm
Department of Medical Physiology, The Panum Institute, University of Copenhagen, Denmark and Department of Internal Medicine and Endocrinology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark
J Endocrinol 169:33-41. 2001..We finally conclude that in the presence of both oestrogen and progesterone this effect of beta(2)-adrenoceptor stimulation is restrained...
Desensitization of beta2-adrenoceptor function in non-pregnant rat myometrium is modulated by sex steroidsT Engstrøm
Department of Internal Medicine and Endocrinology, Herlev Hospital, University of Copenhagen, Denmark
J Endocrinol 170:147-55. 2001....
