- Serum-stable RNA aptamers to urokinase-type plasminogen activator blocking receptor bindingDaniel Miotto Dupont
Department of Molecular Biology, University of Aarhus, DK 8000 Aarhus C, Denmark
RNA 16:2360-9. 2010..uPA-scavenging 2'-fluoro-pyrimidine-modified RNA aptamers represent a novel promising principle for interfering with the pathological functions of the uPA system...
- Nucleic acid aptamers against proteasesD M Dupont
Department of Molecular Biology, Aarhus University, Gustav Wieds Vej 10C, 8000 Aarhus C, Denmark
Curr Med Chem 18:4139-51. 2011....
- Biochemical properties of plasminogen activator inhibitor-1Daniel Miotto Dupont
Department of Molecular Biology, University of Aarhus, Gustav Wieds Vej 10C, 8000 Aarhus C, Denmark
Front Biosci 14:1337-61. 2009..PAI-1, in its active state, also binds to the extracellular protein vitronectin. When in complex with its target proteases, it binds with high affinity to endocytosis receptors of the low density receptor family...