Flemming Dela

Summary

Affiliation: University of Copenhagen
Country: Denmark

Publications

  1. ncbi Patients with type 2 diabetes have normal mitochondrial function in skeletal muscle
    R Boushel
    Department of Exercise Science, Concordia University, Montreal, QC, Canada
    Diabetologia 50:790-6. 2007
  2. ncbi Other adaptations to training/inactivity in type 2 diabetics and other groups with insulin resistance: emphasis on prevention of CHD
    Flemming Dela
    Department of Medical Physiology, Copenhagen Muscle Research Centre, University of Copenhagen, Denmark
    Appl Physiol Nutr Metab 32:602-6. 2007
  3. ncbi Physical training may enhance beta-cell function in type 2 diabetes
    Flemming Dela
    Copenhagen Muscle Research Centre, The Panum Institute, University of Copenhagen, 2200 Copenhagen N, Denmark
    Am J Physiol Endocrinol Metab 287:E1024-31. 2004
  4. ncbi Impact of physical inactivity on subcutaneous adipose tissue metabolism in healthy young male offspring of patients with type 2 diabetes
    Lise Højbjerre
    Department of Biomedical Sciences, Center for Healthy Aging, University of Copenhagen, Copenhagen, Denmark
    Diabetes 59:2790-8. 2010
  5. ncbi Impaired endothelial function and insulin action in first-degree relatives of patients with type 2 diabetes mellitus
    Mette P Sonne
    Department of Biomedical Sciences, Section of Systems Biology Research, Faculty of Health Sciences, University of Copenhagen, 2200 Copenhagen, Denmark
    Metabolism 58:93-101. 2009
  6. ncbi Reduced skeletal muscle mitochondrial respiration and improved glucose metabolism in nondiabetic obese women during a very low calorie dietary intervention leading to rapid weight loss
    Rasmus Rabøl
    Center for Healthy Aging, Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen, DK 2200 Copenhagen, Denmark
    Metabolism 58:1145-52. 2009
  7. ncbi Effect of 10 days of bedrest on metabolic and vascular insulin action: a study in individuals at risk for type 2 diabetes
    Mette P Sonne
    Center for Healthy Ageing, Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
    J Appl Physiol 108:830-7. 2010
  8. ncbi Dual regulation of muscle glycogen synthase during exercise by activation and compartmentalization
    Clara Prats
    Copenhagen Muscle Research Center, Center for Healthy Ageing, Department of Biomedical Sciences, University of Copenhagen, DK 2200 Copenhagen N, Denmark
    J Biol Chem 284:15692-700. 2009
  9. ncbi Endothelial function after 10 days of bed rest in individuals at risk for type 2 diabetes and cardiovascular disease
    Mette P Sonne
    Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen, Blegdamsvej 3, DK 2200 Copenhagen N, Denmark
    Exp Physiol 96:1000-9. 2011
  10. ncbi Contraction-mediated glucose uptake is increased in men with impaired glucose tolerance
    Camilla Skov Jensen
    Copenhagen Muscle Research Centre, Department of Biomedical Sciences, University of Copenhagen, Blegdamsvej 3, 2200 Kbh N, Denmark
    Appl Physiol Nutr Metab 32:115-24. 2007

Collaborators

Detail Information

Publications58

  1. ncbi Patients with type 2 diabetes have normal mitochondrial function in skeletal muscle
    R Boushel
    Department of Exercise Science, Concordia University, Montreal, QC, Canada
    Diabetologia 50:790-6. 2007
    ....
  2. ncbi Other adaptations to training/inactivity in type 2 diabetics and other groups with insulin resistance: emphasis on prevention of CHD
    Flemming Dela
    Department of Medical Physiology, Copenhagen Muscle Research Centre, University of Copenhagen, Denmark
    Appl Physiol Nutr Metab 32:602-6. 2007
    ..The mechanism for the positive effect of physical training may be a reduction of known risk factors for atherosclerosis, but a direct effect on the atherosclerotic process per se cannot be excluded...
  3. ncbi Physical training may enhance beta-cell function in type 2 diabetes
    Flemming Dela
    Copenhagen Muscle Research Centre, The Panum Institute, University of Copenhagen, 2200 Copenhagen N, Denmark
    Am J Physiol Endocrinol Metab 287:E1024-31. 2004
    ..The improved beta-cell function does not require changes in insulin sensitivity and Hb A(1c) concentration...
  4. ncbi Impact of physical inactivity on subcutaneous adipose tissue metabolism in healthy young male offspring of patients with type 2 diabetes
    Lise Højbjerre
    Department of Biomedical Sciences, Center for Healthy Aging, University of Copenhagen, Copenhagen, Denmark
    Diabetes 59:2790-8. 2010
    ..Using a positive family history of type 2 diabetes as a marker of increased genetic risk, the aim of this study was to investigate the impact of physical inactivity on adipose tissue (AT) metabolism in FDR subjects...
  5. ncbi Impaired endothelial function and insulin action in first-degree relatives of patients with type 2 diabetes mellitus
    Mette P Sonne
    Department of Biomedical Sciences, Section of Systems Biology Research, Faculty of Health Sciences, University of Copenhagen, 2200 Copenhagen, Denmark
    Metabolism 58:93-101. 2009
    ..It remains to be established whether FDR also demonstrate impaired insulin-stimulated microvascular function...
  6. ncbi Reduced skeletal muscle mitochondrial respiration and improved glucose metabolism in nondiabetic obese women during a very low calorie dietary intervention leading to rapid weight loss
    Rasmus Rabøl
    Center for Healthy Aging, Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen, DK 2200 Copenhagen, Denmark
    Metabolism 58:1145-52. 2009
    ....
  7. ncbi Effect of 10 days of bedrest on metabolic and vascular insulin action: a study in individuals at risk for type 2 diabetes
    Mette P Sonne
    Center for Healthy Ageing, Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
    J Appl Physiol 108:830-7. 2010
    ..The changes were most pronounced in the CON group. In the FDR group, insulin resistance was already present before bedrest, but even this group displayed a high sensitivity to changes in daily physical activity...
  8. ncbi Dual regulation of muscle glycogen synthase during exercise by activation and compartmentalization
    Clara Prats
    Copenhagen Muscle Research Center, Center for Healthy Ageing, Department of Biomedical Sciences, University of Copenhagen, DK 2200 Copenhagen N, Denmark
    J Biol Chem 284:15692-700. 2009
    ..After overnight low muscle glycogen level and/or in response to exhausting exercise-induced glycogenolysis, GS is associated with spherical structures at the I-band of sarcomeres...
  9. ncbi Endothelial function after 10 days of bed rest in individuals at risk for type 2 diabetes and cardiovascular disease
    Mette P Sonne
    Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen, Blegdamsvej 3, DK 2200 Copenhagen N, Denmark
    Exp Physiol 96:1000-9. 2011
    ..In FDR, a further deterioration of FBF with inactivity is not possible...
  10. ncbi Contraction-mediated glucose uptake is increased in men with impaired glucose tolerance
    Camilla Skov Jensen
    Copenhagen Muscle Research Centre, Department of Biomedical Sciences, University of Copenhagen, Blegdamsvej 3, 2200 Kbh N, Denmark
    Appl Physiol Nutr Metab 32:115-24. 2007
    ..Humans with IGT are resistant to insulin-stimulated but not to exercise-induced glucose uptake...
  11. ncbi Cardiovascular disease markers in type 2 diabetes: the effects of a moderate home-based exercise training programme
    Celena Scheede-Bergdahl
    Centre for Healthy Ageing, Department of Biomedical Sciences, University of Copenhagen, Denmark
    Diab Vasc Dis Res 6:291-6. 2009
    ....
  12. ncbi Effect of physical training on insulin secretion and action in skeletal muscle and adipose tissue of first-degree relatives of type 2 diabetic patients
    Flemming Dela
    Center for Healthy Aging, Department of Biomedical Sciences, University of Copenhagen, Blegdamsvej 3, Copenhagen, Denmark
    Am J Physiol Endocrinol Metab 299:E80-91. 2010
    ..Maximal GU rates are similar between groups and increases with physical training...
  13. ncbi Skeletal muscle mitochondrial function in polycystic ovarian syndrome
    Rasmus Rabøl
    Department of Biomedical Sciences, Faculty of Health Sciences, Center for Healthy Aging, University of Copenhagen, Blegdamsvej 3b, DK 2200 Copenhagen N, Denmark
    Eur J Endocrinol 165:631-7. 2011
    ..We measured mitochondrial respiration in lean and obese women with and without PCOS using high-resolution respirometry...
  14. ncbi Effect of gender on lipid-induced insulin resistance in obese subjects
    Bodil Vistisen
    Department of Biomedical Sciences, The Panum Institute, The Copenhagen Muscle Research Centre, University of Copenhagen, Blegdamsvej 3, DK 2200 Copenhagen N, Denmark
    Eur J Endocrinol 158:61-8. 2008
    ..However, neither the lipid-induced reduction of glucose disposal nor the intramyocellular lipid deposition has been compared directly in obese females and males...
  15. ncbi Insulin and non-insulin mediated vasodilation and glucose uptake in patients with type 2 diabetes
    Celena Scheede-Bergdahl
    Centre for Healthy Aging, Department of Biomedical Sciences, Section of Systems Biology Research, Faculty of Health Sciences, University of Copenhagen, Blegdamsvej 3, DK 2200 Copenhagen N, Denmark
    Diabetes Res Clin Pract 85:243-51. 2009
    ....
  16. ncbi Increased lipolysis but diminished gene expression of lipases in subcutaneous adipose tissue of healthy young males with intrauterine growth retardation
    Lise Højbjerre
    Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen, Denmark
    J Appl Physiol 111:1863-70. 2011
    ..Subjects with IUGR exhibit primary defects in adipose tissue metabolism...
  17. ncbi Effect of hyperglycemia on mitochondrial respiration in type 2 diabetes
    Rasmus Rabøl
    Department of Biomedical Sciences, Faculty of Health Sciences, Copenhagen Muscle Research Centre, University of Copenhagen, Copenhagen, Denmark
    J Clin Endocrinol Metab 94:1372-8. 2009
    ..Whether hyperglycemia inhibits mitochondrial biogenesis and/or function is unknown. This study examined the effect of different levels of glycemia on skeletal muscle mitochondrial function in patients with T2DM...
  18. ncbi Strength training increases insulin-mediated glucose uptake, GLUT4 content, and insulin signaling in skeletal muscle in patients with type 2 diabetes
    Mads K Holten
    Department of Medical Physiology, The Panum Institute, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
    Diabetes 53:294-305. 2004
    ..The adaptation is attributable to local contraction-mediated mechanisms involving key proteins in the insulin signaling cascade...
  19. ncbi Impact of physical inactivity on adipose tissue low-grade inflammation in first-degree relatives of type 2 diabetic patients
    Lise Højbjerre
    Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark
    Diabetes Care 34:2265-72. 2011
    ..We investigated whether subjects who are nonobese FDRs show signs of low-grade inflammation before or after exposure to short-term physical inactivity...
  20. ncbi Mitochondrial respiration in subcutaneous and visceral adipose tissue from patients with morbid obesity
    Regitze Kraunsøe
    Center for Healthy Ageing, Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
    J Physiol 588:2023-32. 2010
    ..Oxidative phosphorylation has a higher relative activity in visceral compared with subcutaneous adipose tissue...
  21. ncbi Effects of strength training on muscle lactate release and MCT1 and MCT4 content in healthy and type 2 diabetic humans
    Carsten Juel
    Department of Medical Physiology, The Panum Institute, University of Copenhagen, Blegdamsvej 3, DK 2200 Copenhagen N, Denmark
    J Physiol 556:297-304. 2004
    ..Conclusions: MCT1 content in skeletal muscle in Type 2 is lower compared with healthy men. Strength training increases MCT1 content in healthy men and in Type 2, thus normalizing the content in Type 2...
  22. ncbi Glucose clearance is higher in arm than leg muscle in type 2 diabetes
    David B Olsen
    Copenhagen Muscle Research Centre, University Hospital Rigshospitalet, Section 7652, DK 2100 Copenhagen, Denmark
    J Physiol 565:555-62. 2005
    ..In conclusion, this study shows that glucose clearance is higher in arm than leg muscles, regardless of insulin resistance, which may indicate better preserved insulin sensitivity in arm than leg muscle in type 2 diabetes...
  23. ncbi Are blood flow and lipolysis in subcutaneous adipose tissue influenced by contractions in adjacent muscles in humans?
    Bente Stallknecht
    Department of Medical Physiology, The Panum Institute, Blegdamsvej 3, DK 2200 Copenhagen N, Denmark
    Am J Physiol Endocrinol Metab 292:E394-9. 2007
    ..Thus specific exercises can induce "spot lipolysis" in adipose tissue...
  24. ncbi Effects of physical training on endothelial function and limb blood flow in type 2 diabetes
    Mette Paulli Sonne
    Copenhagen Muscle Research Centre, Department of Biomedical Sciences, Section of Systems Biology, University of Copenhagen, Blegdamsvej 3, 2200 Kbh N, Denmark
    Appl Physiol Nutr Metab 32:936-41. 2007
    ..In general, physical training can improve endothelial function when this is impaired. However, physical training does not seem to have any effect on endothelial function when this is normal...
  25. ncbi Altered mitochondrial regulation in quadriceps muscles of patients with COPD
    Ashley I Naimi
    Centre for Healthy Aging, Department of Biomedical Sciences, University of Copenhagen, Denmark
    Clin Physiol Funct Imaging 31:124-31. 2011
    ..These results indicate that quadriceps muscle mitochondrial function is altered in patients with COPD. The regulatory mechanisms underlying these functional abnormalities remain to be uncovered...
  26. ncbi Metallothionein-mediated antioxidant defense system and its response to exercise training are impaired in human type 2 diabetes
    Celena Scheede-Bergdahl
    The Copenhagen Muscle Research Centre, The Panum Institute, Department of Medical Physiology, University of Copenhagen, Blegdamsvej 3, DK 2200 Copenhagen N, Denmark
    Diabetes 54:3089-94. 2005
    ..This study presents a novel candidate in the pathogenesis of complications related to oxidative stress in type 2 diabetes...
  27. ncbi Interstitial concentrations of adipokines in subcutaneous abdominal and femoral adipose tissue
    Ninna Bo Nielsen
    Department of Biomedical Sciences, University of Copenhagen, DK 2200 Copenhagen N, Denmark
    Regul Pept 155:39-45. 2009
    ..Furthermore, subcutaneous adipose tissue has a marked production of pro-inflammatory adipokines...
  28. ncbi Effect of training on muscle triacylglycerol and structural lipids: a relation to insulin sensitivity?
    Jørn W Helge
    Department of Medical Physiology, Copenhagen Muscle Research Centre, The Panum Institute, University of Copenhagen, Copenhagen, Denmark
    Diabetes 52:1881-7. 2003
    ..In contrast, training induced a minor increase in the content of phospholipid fatty acid membrane polyunsaturates, which may indicate that membrane lipids may have a role in the training-induced increase in insulin sensitivity...
  29. ncbi Resistance training, insulin sensitivity and muscle function in the elderly
    Flemming Dela
    Institute for Biomedical Sciences, University of Copenhagen, Denmark
    Essays Biochem 42:75-88. 2006
    ....
  30. ncbi 5'AMP activated protein kinase expression in human skeletal muscle: effects of strength training and type 2 diabetes
    Jørgen F P Wojtaszewski
    The Institute of Exercise and Sport Sciences, The Copenhagen Muscle Research Centre, University of Copenhagen, 13 Universitetsparken, 2100 Copenhagen, Denmark
    J Physiol 564:563-73. 2005
    ....
  31. ncbi High-fat feeding inhibits exercise-induced increase in mitochondrial respiratory flux in skeletal muscle
    Mette Skovbro
    Xlab, Center for Healthy Aging, Dept of Biomedical Sciences, Faculty of Health Sciences, Bldg 12 4 7, Univ of Copenhagen, Blegdamsvej 3b, 2200 Copenhagen N, Denmark
    J Appl Physiol 110:1607-14. 2011
    ..The effect of HFD is present even without effects on insulin sensitivity and intramyocellular lipid accumulation. An isocaloric high-fat diet does not cause insulin resistance...
  32. ncbi Effect of intermittent fasting and refeeding on insulin action in healthy men
    Nils Halberg
    Dept of Muscle Research Centre, The Panum Institute, University of Copenhagen, Denmark
    J Appl Physiol 99:2128-36. 2005
    ..3,860 +/- 784 ng/ml, P = 0.02). This experiment is the first in humans to show that intermittent fasting increases insulin-mediated glucose uptake rates, and the findings are compatible with the thrifty gene concept...
  33. ncbi [Physical activity and chronic disease III. Musculoskeletal diseases and lung diseases]
    Peter Magnusson
    H:S Bispebjerg Hospital, Medicinsk Center
    Ugeskr Laeger 166:1552-7. 2004
  34. ncbi [Physical activity and chronic disease I. Heart disease and hypertension]
    Peter Magnusson
    H:S Bispebjerg Hospital, Medicinsk Center
    Ugeskr Laeger 166:1543-7. 2004
  35. ncbi [Physical activity and chronic disease II. Type 2 diabetes, obesity and cancer]
    Peter Magnusson
    H:S Bispebjerg Hospital, Medicinsk Center
    Ugeskr Laeger 166:1547-51. 2004
  36. ncbi [Physical training in the treatment of metabolic syndrome]
    Flemming Dela
    Center for Muskelforskning, Medicinsk Fysiologisk Institut, Panum Instituttet 12 4 7, Københavns Universitet, DK 2200 København N
    Ugeskr Laeger 164:2147-52. 2002
    ..The results are more doubtful for the dyslipidaemia and hypertension, but if the training is combined with an appropriate diet, these abnormalities are also correctable...
  37. ncbi Acute exercise increases adipose tissue interstitial adiponectin concentration in healthy overweight and lean subjects
    Lise Højbjerre
    Department of Biomedical Sciences, The Panum Institute, The Copenhagen Muscle Research Centre, University of Copenhagen, Blegdamsvej 3, DK 2200 Copenhagen N, Denmark
    Eur J Endocrinol 157:613-23. 2007
    ..We studied how an acute bout of exercise influences expression and concentration of adiponectin and regulators of adiponectin in adipose tissue and plasma...
  38. ncbi Mitochondrial oxidative function and type 2 diabetes
    Rasmus Rabøl
    The Copenhagen Muscle Research Centre, The Panum Institute, Department of Medical Physiology, University of Copenhagen, Blegdamsvej 3, DK 2200 Copenhagen N, Denmark
    Appl Physiol Nutr Metab 31:675-83. 2006
    ..Specific effects of regular physical training and muscular work on mitochondrial function and plasticity in type 2 diabetes remain an important area of research...
  39. ncbi Effect of resistance training on Na,K pump and Na+/H+ exchange protein densities in muscle from control and patients with type 2 diabetes
    Flemming Dela
    Department of Medical Physiology, University of Copenhagen, Copenhagen, Denmark
    Pflugers Arch 447:928-33. 2004
    ..06) in trained compared to untrained leg in the diabetics. Thus, a limited amount of strength-training is able to increase the Na,K-pump subunit and isoform content both in controls and in patients with type 2 diabetes...
  40. ncbi Circulating levels of TNF-alpha and IL-6-relation to truncal fat mass and muscle mass in healthy elderly individuals and in patients with type-2 diabetes
    Maria Pedersen
    Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    Mech Ageing Dev 124:495-502. 2003
    ..Furthermore, TNF-alpha was related to lower ASM and BCM, suggesting that TNF-alpha contributes to sarcopenia in ageing...
  41. ncbi Cardiovascular control during exercise: insights from spinal cord-injured humans
    Flemming Dela
    Department of Medical Physiology, The Panum Institute, Building 12 4 7, Blegdamsvej 3, DK 2200 Copenhagen N, Denmark
    Circulation 107:2127-33. 2003
    ..We studied the role of the central nervous system, neural feedback from contracting skeletal muscles, and sympathetic activity to the heart in the control of heart rate and blood pressure during 2 levels of dynamic exercise...
  42. ncbi Educating health professionals: the Avicenna project
    David Gordon
    Faculty of Health Sciences, University of Copenhagen, Copenhagen DK-2200, Denmark
    Lancet 371:966-7. 2008
  43. ncbi The outcome of bone mineral density measurements on patients referred from general practice
    Sofia Inez Iqbal
    Depart of Medical Physiology/Copenhagen Muscle Research Centre, Section of Pathophysiology, The Panum Institute, University of Copenhagen, Copenhagen, Denmark
    J Clin Densitom 8:178-82. 2005
    ..A low BMI is a good indicator for referral of women less than 60 yr for measurements of bone density. Forty-five percent of the referred women from general practitioners had a normal BMD...
  44. ncbi Effect of hyperglycemia and hyperinsulinemia on the response of IL-6, TNF-alpha, and FFAs to low-dose endotoxemia in humans
    Rikke Krogh-Madsen
    Professor of Internal Medicine, Dept of Infectious Diseases 7641, Univ Hospital Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen Ø, Denmark
    Am J Physiol Endocrinol Metab 286:E766-72. 2004
    ....
  45. ncbi Insulin secretion and cellular glucose metabolism after prolonged low-grade intralipid infusion in young men
    Christine B Jensen
    Department of Endocrinology and Clinical Research Unit, Hvidovre University Hospital, 2650 Hvidovre, Denmark
    J Clin Endocrinol Metab 88:2775-83. 2003
    ..Moreover, insulin hypersecretion perfectly countered the free-fatty acid-induced insulin resistance. Future studies are needed to determine the role of a prolonged moderate lipid load in subjects at increased risk of developing diabetes...
  46. ncbi Proteome analysis reveals phosphorylation of ATP synthase beta -subunit in human skeletal muscle and proteins with potential roles in type 2 diabetes
    Kurt Højlund
    Diabetes Research Centre, Department of Endocrinology, Odense University Hospital, Denmark
    J Biol Chem 278:10436-42. 2003
    ....
  47. ncbi Early differential defects of insulin secretion and action in 19-year-old caucasian men who had low birth weight
    Christine B Jensen
    Department of Endocrinology and Clinical Research Unit, Hvidovre University Hospital, Hvidovre, Denmark
    Diabetes 51:1271-80. 2002
    ..We propose that reduced insulin-stimulated glycolysis precedes overt insulin resistance in LBW men. A lower insulin secretion may contribute to impaired glucose tolerance and ultimately lead to diabetes...
  48. ncbi Insulin secretion in lipodystrophic HIV-infected patients is associated with high levels of nonglucose secretagogues and insulin resistance of beta-cells
    Steen B Haugaard
    Department of Infectious Diseases, Hvidovre University Hospital, DK 2650, Copenhagen, Denmark
    Am J Physiol Endocrinol Metab 287:E677-85. 2004
    ....
  49. ncbi Glucose production, oxidation and disposal correlate with plasma lactate levels in HIV-infected patients on HAART
    Steen B Haugaard
    Department of Infectious Diseases, Hvidovre University Hospital, DK 2650 Hvidovre, Copenhagen, Denmark
    J Infect 54:89-97. 2007
    ..However, the correlation between fasting lactate and mitochondrial DNA may be weak or absent, implicating that other factors e.g. glucose turnover may contribute to hyperlactatemia...
  50. ncbi [Prevention of obesity among children and adolescents--proposal for a strategy]
    Christian Mølgaard
    Motions og Ernaeringsrådet, Søborg
    Ugeskr Laeger 169:2314-6. 2007
    ....
  51. ncbi Tumor necrosis factor alpha is associated with insulin-mediated suppression of free fatty acids and net lipid oxidation in HIV-infected patients with lipodystrophy
    Steen B Haugaard
    Department of Infectious Diseases, Hvidovre University Hospital, Hvidovre, DK 2650 Copenhagen, Denmark
    Metabolism 55:175-82. 2006
    ..Furthermore, FFA may be a major determinant of LIPOX in HIV-infected patients on highly active antiretroviral therapy...
  52. ncbi [Eating for top performance in sports?]
    Jørn Wulff Helge
    Københavns Universitet, Medicinsk Fysiologisk Institut, København N
    Ugeskr Laeger 168:4510. 2006
  53. ncbi The effect of caffeine on glucose kinetics in humans--influence of adrenaline
    Danielle S Battram
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada
    J Physiol 569:347-55. 2005
    ....
  54. ncbi Defective glucose and lipid metabolism in human immunodeficiency virus-infected patients with lipodystrophy involve liver, muscle tissue and pancreatic beta-cells
    Steen B Haugaard
    Department of Infectious Diseases, Hvidovre University Hospital, Copenhagen, Denmark
    Eur J Endocrinol 152:103-12. 2005
    ..Aiming to provide a detailed description of the metabolic adverse effects of HIV-lipodystrophy, we investigated several aspects of glucose metabolism, lipid metabolism and beta-cell function in lipodystrophic HIV-infected patients...
  55. ncbi Depleted skeletal muscle mitochondrial DNA, hyperlactatemia, and decreased oxidative capacity in HIV-infected patients on highly active antiretroviral therapy
    Steen B Haugaard
    Department of Infectious Diseases, Hvidovre University Hospital, Copenhagen, Denmark
    J Med Virol 77:29-38. 2005
    ..Further, HIV may deplete sm-mtDNA of NAIVE, which in part could be mediated through an enhanced pro-inflammatory response...
  56. ncbi The CSF and arterial to internal jugular venous hormonal differences during exercise in humans
    Mads K Dalsgaard
    Department of Anaesthesia, Rigshospitalet 2041, Blegdamsvej 9, DK 2100 Copenhagen Ø, Denmark
    Exp Physiol 89:271-7. 2004
    ..The results support the notion that the exercise-induced changes in brain metabolism are controlled by factors intrinsic to the brain...
  57. ncbi Oxidative stress and mitochondrial impairment can be separated from lipofuscin accumulation in aged human skeletal muscle
    Eveline Hutter
    Department for Molecular and Cellular Biology, Institute for Biomedical Aging Research of the Austrian Academy of Sciences, 6020 Innsbruck, Austria
    Aging Cell 6:245-56. 2007
    ..The data support a model, where ROS-induced molecular damage is continuously removed, preventing the accumulation of dysfunctional mitochondria despite ongoing ROS production...
  58. ncbi Young, low-birth-weight men are not more susceptible to the diabetogenic effects of a prolonged free fatty acid exposure than matched controls
    Christine B Jensen
    Steno Diabetes Center, DK 2820 Gentofte, Denmark
    Metabolism 54:1398-406. 2005
    ..We reproduced our previous finding of lower insulin-stimulated glycolysis in this population...