Research Topics
Species | E M BladbjergSummaryAffiliation: University of Southern Denmark Country: Denmark Publications
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Detail Information
Publications
Effects of different progestin regimens in hormone replacement therapy on blood coagulation factor VII and tissue factor pathway inhibitorE M Bladbjerg
Department for Thrombosis Research, University of Southern Denmark, Denmark
Hum Reprod 17:3235-41. 2002..In such women the arterial intima can express tissue factor, and changes in coagulation factor VII (factor VII) and tissue factor pathway inhibitor (TFPI) may be deleterious...
Internal quality control of PCR-based genotyping methods in research studies and patient diagnosticsElse Marie Bladbjerg
Department of Thrombosis Research, University of Southern Denmark, Ribe County Hospital Esbjerg
Thromb Haemost 87:812-6. 2002..Control of data handling revealed 0.1% reading mistakes and 0.5% entry mistakes. Based on our experiences we propose an internal quality control programme for widely used PCR-based haemostasis polymorphism analyses...
Internal quality control of PCR-based genotyping methods: practical experiencesElse Marie Bladbjerg
Department for Thrombosis Research, University of Southern Denmark, Department of Clinical Biochemistry, Ribe County Hospital, Esbjerg, Denmark
Vascul Pharmacol 39:127-9. 2002..Control of data handling revealed 0.1% reading mistakes and 0.5% entry mistakes. Based on our experiences, we propose an internal quality control programme for widely used PCR-based haemostasis polymorphism analyses...
Effect of long-term hormone replacement therapy on tissue factor pathway inhibitor and thrombin activatable fibrinolysis inhibitor in healthy postmenopausal women: a randomized controlled studyE M Bladbjerg
Department for Thrombosis Research, University of Southern Denmark, Ribe County Hospital, Finsensgade 35, DK 6700 Esbjerg, Denmark
J Thromb Haemost 1:1208-14. 2003..05). The hormone effects on TFPI and TAFI were similar in smokers and non-smokers and in women using unopposed and opposed therapy. The observed decrease in TFPI may contribute to the increased cardiovascular risk associated with HRT...
In vitro effects of heparin and tissue factor pathway inhibitor on factor VII assays. possible implications for measurements in vivo after heparin therapyE M Bladbjerg
Department of Thrombosis Research, University of Southern Denmark, Ribe County Hospital in Esbjerg
Blood Coagul Fibrinolysis 11:739-45. 2000..The observed effect of heparin on FVII:Ag should be investigated further...
Dietary factor VII activation does not increase plasma concentrations of prothrombin fragment 1+2 in patients with stable angina pectoris and coronary atherosclerosisE M Bladbjerg
Department of Thrombosis Research, The University of Southern Denmark, Esbjerg
Arterioscler Thromb Vasc Biol 20:2494-9. 2000..However, a local thrombin generation on the plaque surface cannot be excluded...
Plasma concentrations of blood coagulation factor VII measured by immunochemical and amidolytic methodsE M Bladbjerg
Department of Thrombosis Research, University of Southern Denmark, Esbjerg
Scand J Clin Lab Invest 60:161-8. 2000....
Genetic influence on thrombotic risk markers in the elderly--a Danish twin studyE M Bladbjerg
Department for Thrombosis Research, University of Southern Denmark, Ribe County Hospital, Esbjerg, Denmark
J Thromb Haemost 4:599-607. 2006..The genetic contribution to cardiovascular disease (CVD) decreases with increasing age, and it is therefore important to determine the heritability of hemostasis also in the elderly...
Longevity is independent of common variations in genes associated with cardiovascular riskE M Bladbjerg
Department of Thrombosis Research, University of Southern Denmark
Thromb Haemost 82:1100-5. 1999....
A high-fat meal does not activate blood coagulation factor VII in minipigsA K Olsen
Department of Thrombosis Research, University of Southern Denmark
Blood Coagul Fibrinolysis 12:117-22. 2001..001). As a high-fat meal does not seem to activate blood coagulation FVII in minipigs, the pig is apparently not a relevant model for the study of dietary FVII activation and thrombin generation...
DNA-polymorphisms and plasma levels of vascular disease risk factors in Greenland Inuit--is there a relation with the low risk of cardiovascular disease in the Inuit?M P de Maat
Department of Thrombosis Research, University of Southern Denmark, Ribe County Hospital, Esbjerg
Thromb Haemost 81:547-52. 1999....
No association between hip geometry and four common polymorphisms associated with fracture: the Danish osteoporosis prevention studyN Nissen
Department of Endocrinology, Odense University Hospital, University of Southern Denmark, Odense, 5000, Odense C, Denmark
Calcif Tissue Int 84:276-85. 2009..05). The geometric dimensions of the proximal femur in perimenopausal women are not associated with the MTHFR c.677C > T, P2X(7) (Glu496Ala), P2X(7) (Ile568Asn), and LRP5 exon 9 (c.266A > G) polymorphisms...
Inflammation, thrombosis and atherosclerosis: results of the Glostrup studyM P M De Maat
Department for Thrombosis Research, University of Southern Denmark and Department of Clinical Biochemistry, Ribe County Hospital, Esbjerg, Denmark
J Thromb Haemost 1:950-7. 2003..In conclusion, in the Glostrup population study, thrombosis and inflammation are associated with the severity of atherosclerosis, as reflected by IMT and plaque occurrence...
Estrogen receptor 1 haplotype does not regulate oral contraceptive-induced changes in haemostasis and inflammation risk factors for venous and arterial thrombosisMoniek P M de Maat
Department of Thrombosis Research, University of Southern Denmark and Ribe County Hospital, Esbjerg, Denmark
Hum Reprod 21:1473-6. 2006..Individuals show large differences in the response of these variables to OCs. Polymorphism in the estrogen receptor-1 (ER1) gene may explain part of this inter-individual response...
Tissue-type plasminogen activator and C-reactive protein in acute coronary heart disease. A nested case-control studyJ Gram
Department of Clinical Biochemistry, Ribe County Hospital, South Jutland University Centre, Esbjerg, Denmark
J Intern Med 247:205-12. 2000..To study the importance of inflammation and fibrinolysis for evolution of ischaemic heart disease in a cohort of initially healthy subjects...
Subclinical hypothyroidism is associated with a low-grade inflammation, increased triglyceride levels and predicts cardiovascular disease in males below 50 yearsJ Kvetny
Section of Endocrinology, Department of Internal Medicine, Esbjerg County Hospital, Oerum Health Centre, University of Southern Denmark, Esbjerg, Denmark
Clin Endocrinol (Oxf) 61:232-8. 2004..The purpose of the present study was to examine a possible association between subclinical hypothyroidism and cardiovascular disease...
Effect of pre-analytical handling on haematological variables in minipigsA K Olsen
Department of Thrombosis Research, University of Southern Denmark, Esbjerg
Lab Anim 35:147-52. 2001....
Effects of mealtime insulin aspart and bedtime neutral protamine Hagedorn insulin on postprandial coagulation and fibrinolysis in patients with type 2 diabetesE M Bladbjerg
Unit for Thrombosis Research, Institute of Public Health, University of Southern Denmark, Esbjerg, Denmark
Diabetes Obes Metab 14:447-53. 2012..We hypothesized that rapid-acting insulin has a beneficial postprandial effect on coagulation and fibrinolysis compared with intermediate-acting insulin because of its ability to lower postprandial hyperglycaemia...
The Göttingen minipig as a model for postprandial hyperlipidaemia in man: experimental observationsA K Olsen
Department for Thrombosis Research, University of Southern Denmark, Ribe County Hospital, Esbjerg, Denmark
Lab Anim 36:438-44. 2002..There is no need to administer the fat fractionated or to withhold food prior to administration...
Positive impact of hormone replacement therapy on the fibrinolytic system: a long-term randomized controlled study in healthy postmenopausal womenJ S Madsen
Departments of Clinical Biochemistry and Endocrinology, Odense University Hospital, Odense, Denmark
J Thromb Haemost 1:1984-91. 2003..Impaired fibrinolytic function is associated with an enhanced risk of cardiovascular disease and therefore the effect of HRT on fibrinolysis may be of importance...
The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseasesJ Danesh
Eur J Epidemiol 22:839-69. 2007..It will, therefore, help to determine to what extent such associations are independent from possible confounding factors and to what extent such markers (separately and in combination) provide incremental predictive value...
Variations of cardiovascular disease associated genes exhibit sex-dependent influence on human longevityQ Tan
Max-Planck Institute for Demographic Research, Rostock, Germany
Exp Gerontol 36:1303-15. 2001..However, the presence of sex-dependent effects and the fact that major CVD-associated genes failed to impose detrimental influence on longevity lead us to concur that the aging process is highly complicated...
