Research Topics
Genomes and Genes | Jens BangsboSummaryAffiliation: University of Copenhagen Country: Denmark Publications
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Publications
Four weeks of speed endurance training reduces energy expenditure during exercise and maintains muscle oxidative capacity despite a reduction in training volumeF Marcello Iaia
Dept of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark
J Appl Physiol 106:73-80. 2009..Furthermore, speed endurance training can maintain muscle oxidative capacity, capillarization, and endurance performance in already trained individuals despite significant reduction in the amount of training...
Fibre type-specific change in FXYD1 phosphorylation during acute intense exercise in humansMartin Thomassen
Department of Nutrition, Exercise and Sports, Section of Integrated Physiology, University of Copenhagen, August Krogh Building, Universitetsparken 13, 2 sal, 2100 Copenhagen, Denmark
J Physiol 591:1523-33. 2013..This, together with the observation of a higher abundance of the Na(+)-K(+) pump α2 isoform protein in type II fibres, is likely to have importance for the exercise-induced human Na(+)-K(+) pump activity in the different fibre types...
Counterpoint: lactic acid accumulation is a disadvantage during muscle activityJens Bangsbo
Institute of Exercise and Sport Sciences, Copenhagen Muscle Research Centre, Denmark
J Appl Physiol 100:1412-3; discussion 1413-4. 2006
Performance enhancements and muscular adaptations of a 16-week recreational football intervention for untrained womenJ Bangsbo
Department of Exercise and Sport Sciences, Section of Human Physiology, University of Copenhagen, Copenhagen, Denmark
Scand J Med Sci Sports 20:24-30. 2010..Thus, football can be used as an activity to elevate the physical capacity of untrained women...
Effect of two different intense training regimens on skeletal muscle ion transport proteins and fatigue developmentMagni Mohr
Copenhagen Muscle Research Centre, Institute of Exercise and Sport Sciences, Universitetsparken 13, DK 2100 Copenhagen Ø, Denmark
Am J Physiol Regul Integr Comp Physiol 292:R1594-602. 2007..Adaptations with training do have an effect on the metabolic response to exercise and specific improvement in work capacity...
Effects of high-intensity intermittent training on potassium kinetics and performance in human skeletal muscleJens Jung Nielsen
August Krogh Institute, IFI, Universitetsparken 13, DK-2100 Copenhagen, Denmark
J Physiol 554:857-70. 2004....
Thigh oxygen uptake at the onset of intense exercise is not affected by a reduction in oxygen delivery caused by hypoxiaPeter M Christensen
Dept of Exercise and Sport Sciences, August Krogh Bldg, Universitetsparken 13, DK 2100 Copenhagen Ø, Denmark
Am J Physiol Regul Integr Comp Physiol 303:R843-9. 2012..35 ± 0.07 and 0.36 ± 0.07 mmol·kg dry wt(-1)·s(-1) in NOR and HYP). Thus the increase in thigh Vo(2) was not attenuated at the onset of intense knee-extensor exercise despite a reduction in oxygen delivery and pressure...
Muscle and blood metabolites during a soccer game: implications for sprint performancePeter Krustrup
Institute of Exercise and Sport Sciences, Department of Human Physiology, University of Copenhagen, Copenhagen, Denmark
Med Sci Sports Exerc 38:1165-74. 2006..The latter finding may be explained by low glycogen levels in individual muscle fibers. Blood lactate is a poor indicator of muscle lactate during soccer match play...
A test to evaluate the physical impact on technical performance in soccerThomas Rostgaard
Institute of Exercise and Sport Sciences, Department of Human Physiology, University of Copenhagen, Copenhagen, Denmark
J Strength Cond Res 22:283-92. 2008..9 +/- 6.6, 354 +/- 39, and 25.3 +/- 5.9 mmol kg(-1) d.w., respectively. In summary, the PT-test can be used to evaluate a soccer player's technical skills under conditions similar to intense periods of a soccer game...
Neuromuscular blockade of slow twitch muscle fibres elevates muscle oxygen uptake and energy turnover during submaximal exercise in humansPeter Krustrup
Department of Exercise and Sport Sciences, Section of Human Physiology, The August Krogh Building, Universitetsparken 13, DK 2100 Copenhagen Ø, Denmark
J Physiol 586:6037-48. 2008..0 versus 30.9 +/- 1.5%). In conclusion, the present findings provide evidence that FT fibres are less efficient than ST fibres in vivo at a contraction frequency of 1 Hz, and that the muscle VO2 kinetics is slowed by FT fibre activation...
Reduced volume but increased training intensity elevates muscle Na+-K+ pump alpha1-subunit and NHE1 expression as well as short-term work capacity in humansF Marcello Iaia
Department of Exercise and Sport Sciences, Section of Human Physiology, Copenhagen Muscle Research Center, University of Copenhagen, Copenhagen, Denmark
Am J Physiol Regul Integr Comp Physiol 294:R966-74. 2008..Furthermore, performance during intense exercise can be improved and endurance performance maintained even with a reduction in training volume if the intensity of training is very high...
Metabolic response and fatigue in soccerJens Bangsbo
Institute of Exercise and Sport Sciences, University of Copenhagen, Denmark
Int J Sports Physiol Perform 2:111-27. 2007....
Effect of dexamethasone on skeletal muscle Na+,K+ pump subunit specific expression and K+ homeostasis during exercise in humansNikolai Nordsborg
University of Copenhagen, Department of Exercise and Sport Sciences, Section for Human Physiology, Universitetsparken 13, 2100 Copenhagen, Denmark
J Physiol 586:1447-59. 2008..The results indicate that an increased Na(+),K(+) pump expression per se is of importance for thigh K(+) reuptake at the onset of low and moderate intensity exercise, but less important during high intensity exercise...
Potassium kinetics in human muscle interstitium during repeated intense exercise in relation to fatigueMagni Mohr
Institute of Exercise and Sport Sciences, Department of Human Physiology, August Krogh Institute, University of Copenhagen, Universitetsparken 13, 2100, Copenhagen, Denmark
Pflugers Arch 448:452-6. 2004....
Recruitment of fibre types and quadriceps muscle portions during repeated, intense knee-extensor exercise in humansPeter Krustrup
Copenhagen Muscle Research Centre, Institute of Exercise and Sport Sciences, Department of Human Physiology, University of Copenhagen, Universitetsparken 13, 2100 Copenhagen O, Denmark
Pflugers Arch 449:56-65. 2004....
Caffeine intake improves intense intermittent exercise performance and reduces muscle interstitial potassium accumulationMagni Mohr
Copenhagen Muscle Research Centre, Department of Exercise and Sport Sciences, University of Copenhagen, Denmark
J Appl Physiol 111:1372-9. 2011..0 ± 0.6 mmol/l, respectively). No differences in interstitial Na(+) were observed between CAF and CON. In conclusion, caffeine intake enhances fatigue resistance and reduces muscle interstitial K(+) during intense intermittent exercise...
Passive leg movement enhances interstitial VEGF protein, endothelial cell proliferation, and eNOS mRNA content in human skeletal muscleYlva Hellsten
Copenhagen Muscle Research Center, Department of Exercise and Sport Sciences, Section of Human Physiology, University of Copenhagen, DK 2100 Copenhagen, Denmark
Am J Physiol Regul Integr Comp Physiol 294:R975-82. 2008..We propose that enhanced blood flow and passive stretch are positive physiological stimulators of factors associated with capillary growth in human muscle...
Maximal voluntary contraction force, SR function and glycogen resynthesis during the first 72 h after a high-level competitive soccer gamePeter Krustrup
Department of Exercise and Sport Sciences, Section of Human Physiology, University of Copenhagen, Copenhagen, Denmark
Eur J Appl Physiol 111:2987-95. 2011....
The Yo-Yo IR2 test: physiological response, reliability, and application to elite soccerPeter Krustrup
Institute of Exercise and Sport Sciences, Department of Human Physiology, August Krogh Institute, University of Copenhagen, Copenhagen, Denmark
Med Sci Sports Exerc 38:1666-73. 2006..To examine the physiological response, reliability, and validity of the Yo-Yo intermittent recovery level 2 test (Yo-Yo IR2)...
Fatigue in soccer: a brief reviewMagni Mohr
Institute of Exercise and Sport Sciences, Department of Human Physiology, August Krogh Institute, University of Copenhagen, Denmark
J Sports Sci 23:593-9. 2005..In conclusion, fatigue or impaired performance in soccer occurs during various phases in a game, and different physiological mechanisms appear to operate in different periods of a game...
Slow-twitch fiber glycogen depletion elevates moderate-exercise fast-twitch fiber activity and O2 uptakePeter Krustrup
Copenhagen Muscle Research Centre, Institute of Exercise and Sport Sciences, Department of Human Physiology, University of Copenhagen, Copenhagen, Denmark
Med Sci Sports Exerc 36:973-82. 2004..These findings suggest that FT fiber recruitment elevates energy requirement of dynamic exercise in humans and support an important role of active FT fibers in producing the slow component of VO2..
Physical and metabolic demands of training and match-play in the elite football playerJens Bangsbo
Institute of Exercise and Sport Sciences, University of Copenhagen, Copenhagen Muscle Research Centre, Denmark
J Sports Sci 24:665-74. 2006..These differences should be taken into account when planning the training and nutritional strategies of top-class players, who require a significant energy intake during a week...
Muscle adaptations and performance enhancements of soccer training for untrained menPeter Krustrup
Department of Exercise and Sport Sciences, Section of Human Physiology, Copenhagen Muscle Research Centre, University of Copenhagen, The August Krogh Building, Universitetsparken 13, Copenhagen 2100, Denmark
Eur J Appl Physiol 108:1247-58. 2010....
Partial neuromuscular blockade in humans enhances muscle blood flow during exercise independently of muscle oxygen uptake and acetylcholine receptor blockadeYlva Hellsten
Department of Exercise and Sport Sciences, University of Copenhagen, Universitetsparken 13, DK 2100 Copenhagen Ø, Denmark
Am J Physiol Regul Integr Comp Physiol 296:R1106-12. 2009..The enhanced exercise hyperemia during partial neuromuscular blockade may be related to a greater recruitment of fast-twitch muscle fibers...
Reduced volume and increased training intensity elevate muscle Na+-K+ pump alpha2-subunit expression as well as short- and long-term work capacity in humansJens Bangsbo
Department of Exercise and Sport Sciences, Section of Human Physiology, Copenhagen Muscle Research Centre, University of Copenhagen, Copenhagen, Denmark
J Appl Physiol 107:1771-80. 2009....
Tricarboxylic acid cycle intermediates accumulate at the onset of intense exercise in man but are not essential for the increase in muscle oxygen uptakeJens Bangsbo
Copenhagen Muscle Research Centre, Institute of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark
Pflugers Arch 452:737-43. 2006..Am J Physiol 282:R273-R280, 2002), the present data suggest that muscle TCAI accumulate during the initial seconds of exercise; however, this increase is not essential for the contraction-induced increase in mitochondrial respiration...
Contraction-induced increases in Na+-K+-ATPase mRNA levels in human skeletal muscle are not amplified by activation of additional muscle massNikolai Nordsborg
Institute of Exercise and Sport Sciences, University of Copenhagen, Denmark
Am J Physiol Regul Integr Comp Physiol 289:R84-91. 2005..In conclusion, activation of additional muscle mass does not result in a higher exercise-induced increase in Na(+)-K(+)-ATPase subunit-specific mRNA...
Effect of high-intensity intermittent training on lactate and H+ release from human skeletal muscleCarsten Juel
Copenhagen Muscle Research Centre, August Krogh Institute, University of Copenhagen, DK 2100 Copenhagen, Denmark
Am J Physiol Endocrinol Metab 286:E245-51. 2004....
Effect of additional speed endurance training on performance and muscle adaptationsThomas Petursson Gunnarsson
Department of Exercise and Sport Sciences, Section of Human Physiology, University of Copenhagen, Denmark
Med Sci Sports Exerc 44:1942-8. 2012..The present study examined the effect of additional speed endurance training (SET) during the season on muscle adaptations and performance of trained soccer players...
VO2 kinetics and performance in soccer players after intense training and inactivityPeter M Christensen
Copenhagen Muscle Research Centre, Department of Exercise and Sport Sciences, Section of Human Physiology, University of Copenhagen, Copenhagen, Denmark
Med Sci Sports Exerc 43:1716-24. 2011....
Low blood flow at onset of moderate-intensity exercise does not limit muscle oxygen uptakeMichael Nyberg
The Copenhagen Muscle Research Centre, Rigshospitalet, Copenhagen, Denmark
Am J Physiol Regul Integr Comp Physiol 298:R843-8. 2010..Additionally, prostanoids and/or nitric oxide appear to play important roles in elevating skeletal muscle blood flow in the initial phase of exercise...
Protein kinase Cα activity is important for contraction-induced FXYD1 phosphorylation in skeletal muscleMartin Thomassen
Department of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark
Am J Physiol Regul Integr Comp Physiol 301:R1808-14. 2011..In conclusion, exercise induces FXYD1 phosphorylation at multiple sites in human skeletal muscle. In mouse muscles, contraction-induced changes in FXYD1 ser68 phosphorylation are fiber-type specific and dependent on PKCα activity...
Match performance of high-standard soccer players with special reference to development of fatigueMagni Mohr
Institute of Exercise and Sport Sciences, August Krogh Institute, Department of Human Physiology, University of Copenhagen, Universitetsparken 13, DK-2100 Copenhagen O, Denmark
J Sports Sci 21:519-28. 2003....
Effect of 2-wk intensified training and inactivity on muscle Na+-K+ pump expression, phospholemman (FXYD1) phosphorylation, and performance in soccer playersMartin Thomassen
Copenhagen Muscle Research Centre, Department of Exercise and Sport Sciences, Section of Human Physiology, University of Copenhagen, Copenhagen, Denmark
J Appl Physiol 108:898-905. 2010..Resting phosphorylation status of the Na(+)-K(+) pump is changed by training and inactivity and may play a role in performance during repeated, intense exercise...
The Yo-Yo intermittent recovery test : a useful tool for evaluation of physical performance in intermittent sportsJens Bangsbo
Institute of Exercise and Sport Sciences, University of Copenhagen, Copenhagen Muscle Research Centre, Copenhagen, Denmark
Sports Med 38:37-51. 2008..The Yo-Yo IR tests provide a simple and valid way to obtain important information of an individual's capacity to perform repeated intense exercise and to examine changes in performance...
Exercise training alters the balance between vasoactive compounds in skeletal muscle of individuals with essential hypertensionAne H Hansen
Copenhagen Muscle Research Centre, University of Copenhagen, Department of Exercise and Sports Sciences, Universitetsparken 13, DK 2100 Copenhagen Ø, Denmark
Hypertension 58:943-9. 2011....
Metabolic alkalosis reduces exercise-induced acidosis and potassium accumulation in human skeletal muscle interstitiumDarrin Street
Copenhagen Muscle Research Centre, Institute of Molecular Biology and Physiology, August Krogh Building, Copenhagen, Denmark
J Physiol 566:481-9. 2005..The present study demonstrated a link between interstitial H+ and K+ accumulation, which may be through the ATP-sensitive K+ channels (KATP channels), which are sensitive to changes in H+...
Muscle interstitial potassium kinetics during intense exhaustive exercise: effect of previous arm exerciseNikolai Nordsborg
The August Krogh Institute, IFI, Universitetsparken 13, DK-2100 Copenhagen, Denmark
Am J Physiol Regul Integr Comp Physiol 285:R143-8. 2003..The high [K+]i levels reached at exhaustion can be expected to cause fatigue, which is supported by the finding that a faster accumulation of interstitial K+, induced by prior arm exercise, was associated with a reduced time to fatigue...
Physical demands during an elite female soccer game: importance of training statusPeter Krustrup
Institute of Exercise and Sport Sciences, Department of Human Physiology, University of Copenhagen, Denmark
Med Sci Sports Exerc 37:1242-8. 2005..To examine the activity profile and physical loading of elite female soccer players during match play and to study the relationship between training status and physical match performance...
Activity profile and physical demands of football referees and assistant referees in international gamesPeter Krustrup
Department of Exercise and Sport Sciences, Section of Human Physiology, University of Copenhagen, Copenhagen, Denmark
J Sports Sci 27:1167-76. 2009..Referees performing the most high-intensity work are better to keep up with play. The match activities differ significantly between referees and assistant referees, which should be considered in training and testing procedures...
ATP and heat production in human skeletal muscle during dynamic exercise: higher efficiency of anaerobic than aerobic ATP resynthesisPeter Krustrup
Institute of Exercise and Sports Sciences, August Krogh Institute, Department of Human Physiology, University of Copenhagen, Denmark
J Physiol 549:255-69. 2003..Alternatively, mitochondrial efficiency is lowered as exercise progresses, since ATP turnover was unaltered during the ischaemic exercise bout...
Contraction-induced secretion of VEGF from skeletal muscle cells is mediated by adenosineBirgitte Høier
Copenhagen Muscle Research Center, Department of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark
Am J Physiol Heart Circ Physiol 299:H857-62. 2010....
Intense interval training enhances human skeletal muscle oxygen uptake in the initial phase of dynamic exercise at high but not at low intensitiesPeter Krustrup
Copenhagen Muscle Research Centre, Institute of Exercise and Sport Sciences, Department of Human Physiology, University of Copenhagen, Copenhagen, Denmark
J Physiol 559:335-45. 2004..The present data demonstrate that intense interval training elevates muscle oxygen uptake, blood flow and vascular conductance in the initial phase of exercise at high, but not at low, intensities...
The yo-yo intermittent recovery test: physiological response, reliability, and validityPeter Krustrup
Institute of Exercise and Sport Sciences, August Krogh Institute, Department of Human Physiology, University of Copenhagen, Denmark
Med Sci Sports Exerc 35:697-705. 2003..Additionally, the study suggests that fatigue during intense intermittent short-term exercise was unrelated to muscle CP, lactate, pH, and glycogen...
Activity profile and physiological demands of top-class soccer assistant refereeing in relation to training statusPeter Krustrup
Institute of Exercise and Sport Sciences, August Krogh Institute, University of Copenhagen, Denmark
J Sports Sci 20:861-71. 2002....
The slow component of oxygen uptake during intense, sub-maximal exercise in man is associated with additional fibre recruitmentPeter Krustrup
Institute of Exercise and Sport Sciences, Department of Human Physiology, August Krogh Institute, University of Copenhagen, Universitetsparken 13, 2100 Copenhagen, Denmark
Pflugers Arch 447:855-66. 2004..6 min and amounted to 0.24 l min(-1). The present study demonstrates that additional type I and II fibres are recruited with time during intense sub-maximal exercise in temporal association with a significant slow component of VO2...
Match activities of elite women soccer players at different performance levelsMagni Mohr
Institute of Exercise and Sport Sciences, Department of Human Physiology, University of Copenhagen, Denmark
J Strength Cond Res 22:341-9. 2008..The difference in high-intensity running between the 2 levels demonstrates the importance of intense intermittent exercise for match performance in women soccer. Thus, these aspects should be trained intensively in women soccer...
Effect of high-intensity training on exercise-induced gene expression specific to ion homeostasis and metabolismNikolai Nordsborg
Institute of Exercise and Sports Sciences, August Krogh Institute, 2100 Copenhagen, Denmark
J Appl Physiol 95:1201-6. 2003..In conclusion, cellular adaptations to high-intensity exercise training may, in part, be induced by transcriptional regulation. After training, the transcriptional response to an exercise bout at a given workload is diminished...
Localization and function of ATP-sensitive potassium channels in human skeletal muscleJens Jung Nielsen
Copenhagen Muscle Research Centre, August Krogh Institute, and Institute of Exercise and Sports Sciences, Copenhagen, Denmark
Am J Physiol Regul Integr Comp Physiol 284:R558-63. 2003..In contrast to in vitro conditions, the present study demonstrated that under in vivo conditions the KATP channels are active at rest and contribute to the accumulation of interstitial K+...
The copenhagen soccer test: physiological response and fatigue developmentMads Bendiksen
Section of Human Physiology, Department of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark
Med Sci Sports Exerc 44:1595-603. 2012....
Antioxidant supplementation enhances the exercise-induced increase in mitochondrial uncoupling protein 3 and endothelial nitric oxide synthase mRNA content in human skeletal muscleYlva Hellsten
Department of Exercise and Sport Science, Copenhagen Muscle Research Center, University of Copenhagen, DK 2100 Copenhagen, Denmark
Free Radic Biol Med 43:353-61. 2007..The data show that ROS are formed within skeletal muscle during exercise and that oral intake of antioxidants can enhance the exercise-induced adaptive mRNA responses of eNOS and UCP3...
In health and in a normoxic environment, VO2 max is/is not limited primarily by cardiac output and locomotor muscle blood flowJens Bangsbo
Copenhagen Muscle Research Centre, Institute of Exercise and Sport Science, University of Copenhagen, Copenhagen, Denmark
J Appl Physiol 100:1742. 2006
Dexamethasone up-regulates skeletal muscle maximal Na+,K+ pump activity by muscle group specific mechanisms in humansNikolai Nordsborg
August Krogh Institute, Institute of Exercise and Sport Sciences, Universitetsparken 13, 2. floor, 2100 Copenhagen, Denmark
J Physiol 567:583-9. 2005....
High-intensity training in footballF Marcello Iaia
Copenhagen Muscle Research Centre, Department of Exercise and Sport Sciences, Section of Human Physiology, University of Copenhagen, Copenhagen, Denmark
Int J Sports Physiol Perform 4:291-306. 2009..The type and amount of training should be game related and specific to the technical, tactical, and physical demands imposed on each player...
Relationship between performance at different exercise intensities and skeletal muscle characteristicsF Marcello Iaia
Dept of Exercise and Sport Sciences, Section of Human Physiology, August Krogh Bldg, Universitetsparken 13, DK 2100 Copenhagen Ø, Denmark
J Appl Physiol 110:1555-63. 2011..e., ∼30 s. Muscle capillaries and the Na(+)-K(+) pump β(1)-subunit seem to be important determinants for performance during exhaustive high-intensity exercises lasting between 30 s and 4 min...
Soccer improves fitness and attenuates cardiovascular risk factors in hypertensive menPeter Krustrup
Sport and Health Sciences, College of Life and Environmental Sciences, St Luke s Campus, University of Exeter, Exeter, United Kingdom
Med Sci Sports Exerc 45:553-60. 2013..The present study investigated the fitness and health effects of medium-term soccer training for untrained hypertensive middle-age men...
Intense intermittent exercise provides weak stimulus for vascular endothelial growth factor secretion and capillary growth in skeletal muscleB Hoier
Department of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark
Exp Physiol 98:585-97. 2013....
Enhanced pyruvate dehydrogenase activity does not affect muscle O2 uptake at onset of intense exercise in humansJens Bangsbo
Copenhagen Muscle Research Centre, Institute of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark
Am J Physiol Regul Integr Comp Physiol 282:R273-80. 2002..The present findings demonstrate that increasing PDH(a) does not alter muscle O2 uptake and anaerobic ATP provision during the initial phase of intense dynamic knee-extensor exercise in humans...
Muscle K+, Na+, and Cl disturbances and Na+-K+ pump inactivation: implications for fatigueMichael J McKenna
Muscle, Ions and Exercise Group, School of Human Movement, Recreation and Performance, Centre for Ageing, Rehabilitation, Exercise and Sport, Victoria University, Melbourne, Victoria, Australia
J Appl Physiol 104:288-95. 2008..However, during intense contraction some Na(+)-K(+) pumps are inactivated and together with further ionic disturbances, likely precipitate muscle fatigue...
