Luis A Bagatolli

Summary

Affiliation: University of Southern Denmark
Country: Denmark

Publications

  1. ncbi request reprint Direct observation of lipid domains in free standing bilayers: from simple to complex lipid mixtures
    Luis A Bagatolli
    Grupo de Biofisica, Departamento de Química Biológica CIQUIBIC, Facultad de Ciencias Quimicas, Universidad Nacional de Cordoba, Cordoba, Argentina
    Chem Phys Lipids 122:137-45. 2003
  2. ncbi request reprint To see or not to see: lateral organization of biological membranes and fluorescence microscopy
    Luis A Bagatolli
    MEMPHYS Center for Biomembrane Physics, Department of Biochemistry and Molecular Biology, University of Southern Denmark, DK 5230 Odense M, Denmark
    Biochim Biophys Acta 1758:1541-56. 2006
  3. doi request reprint An outlook on organization of lipids in membranes: searching for a realistic connection with the organization of biological membranes
    Luis A Bagatolli
    MEMPHYS Center for Biomembrane Physics, Membrane Biophysics and Biophotonics Group, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campusvej 55, Odense M, Denmark
    Prog Lipid Res 49:378-89. 2010
  4. pmc Morphometric image analysis of giant vesicles: a new tool for quantitative thermodynamics studies of phase separation in lipid membranes
    Peter Husen
    MEMPHYS Center for Biomembrane Physics, University of Southern Denmark, Odense, Denmark
    Biophys J 103:2304-10. 2012
  5. doi request reprint Multiphoton excitation fluorescence microscopy in planar membrane systems
    Jonathan Brewer
    Membrane Biophysics and Biophotonics group MEMPHYS, Center for Biomembrane Physics, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark
    Biochim Biophys Acta 1798:1301-8. 2010
  6. pmc Direct visualization of the lateral structure of porcine brain cerebrosides/POPC mixtures in presence and absence of cholesterol
    Matthias Fidorra
    Membrane Biophysics and Biophotonics group MEMPHYS, Center for Biomembrane Physics, Department of Biochemistry and Molecular Biology, University of Southern Denmark, 5230 Odense, Denmark
    Biophys J 97:142-54. 2009
  7. doi request reprint Spatially resolved two-color diffusion measurements in human skin applied to transdermal liposome penetration
    Jonathan Brewer
    Membrane Biophysics and Biophotonics Group MEMPHYS Center for Biomembrane Physics, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark
    J Invest Dermatol 133:1260-8. 2013
  8. pmc Surface behavior and lipid interaction of Alzheimer beta-amyloid peptide 1-42: a membrane-disrupting peptide
    Ernesto E Ambroggio
    CIQUIBIC CONICET, Departamento de Quimica Biologica, Facultad de Ciencias Quimicas, Ciudad Universitaria, Córdoba CP 5000, Argentina
    Biophys J 88:2706-13. 2005
  9. doi request reprint Impact of membrane-anchored fluorescent probes on the mechanical properties of lipid bilayers
    Hélène Bouvrais
    Department of Physics and Chemistry, MEMPHYS, Center for Biomembrane Physics, University of Southern Denmark, Denmark
    Biochim Biophys Acta 1798:1333-7. 2010
  10. doi request reprint Texture of lipid bilayer domains
    Uffe Bernchou
    Department of Physics and Chemistry, MEMPHYS Center for Biomembrane Physics, University of Southern Denmark, Campusvej 55, DK 5230 Odense M, Denmark
    J Am Chem Soc 131:14130-1. 2009

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Direct observation of lipid domains in free standing bilayers: from simple to complex lipid mixtures
    Luis A Bagatolli
    Grupo de Biofisica, Departamento de Química Biológica CIQUIBIC, Facultad de Ciencias Quimicas, Universidad Nacional de Cordoba, Cordoba, Argentina
    Chem Phys Lipids 122:137-45. 2003
    ....
  2. ncbi request reprint To see or not to see: lateral organization of biological membranes and fluorescence microscopy
    Luis A Bagatolli
    MEMPHYS Center for Biomembrane Physics, Department of Biochemistry and Molecular Biology, University of Southern Denmark, DK 5230 Odense M, Denmark
    Biochim Biophys Acta 1758:1541-56. 2006
    ..Additionally, the advantages of utilizing visual information, to correlate the lateral structure of compositionally simple membranes with complex situations, i.e., biological membranes, will be addressed...
  3. doi request reprint An outlook on organization of lipids in membranes: searching for a realistic connection with the organization of biological membranes
    Luis A Bagatolli
    MEMPHYS Center for Biomembrane Physics, Membrane Biophysics and Biophotonics Group, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campusvej 55, Odense M, Denmark
    Prog Lipid Res 49:378-89. 2010
    ..The need for a new model to replace the celebrated Nicolson-Singer fluid-mosaic model of biological membranes is also discussed...
  4. pmc Morphometric image analysis of giant vesicles: a new tool for quantitative thermodynamics studies of phase separation in lipid membranes
    Peter Husen
    MEMPHYS Center for Biomembrane Physics, University of Southern Denmark, Odense, Denmark
    Biophys J 103:2304-10. 2012
    ....
  5. doi request reprint Multiphoton excitation fluorescence microscopy in planar membrane systems
    Jonathan Brewer
    Membrane Biophysics and Biophotonics group MEMPHYS, Center for Biomembrane Physics, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark
    Biochim Biophys Acta 1798:1301-8. 2010
    ..This correspondence occurs when the lateral pressure of the monolayer is 26+/-2 mN/m and 28+/-3 mN/m for DOPC and DPPC, respectively...
  6. pmc Direct visualization of the lateral structure of porcine brain cerebrosides/POPC mixtures in presence and absence of cholesterol
    Matthias Fidorra
    Membrane Biophysics and Biophotonics group MEMPHYS, Center for Biomembrane Physics, Department of Biochemistry and Molecular Biology, University of Southern Denmark, 5230 Odense, Denmark
    Biophys J 97:142-54. 2009
    ..The observed cholesterol effect largely differs from that reported for POPC/porcine brain ceramide, reflecting the impact of the sphingolipids polar headgroup on the membrane lateral organization...
  7. doi request reprint Spatially resolved two-color diffusion measurements in human skin applied to transdermal liposome penetration
    Jonathan Brewer
    Membrane Biophysics and Biophotonics Group MEMPHYS Center for Biomembrane Physics, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark
    J Invest Dermatol 133:1260-8. 2013
    ....
  8. pmc Surface behavior and lipid interaction of Alzheimer beta-amyloid peptide 1-42: a membrane-disrupting peptide
    Ernesto E Ambroggio
    CIQUIBIC CONICET, Departamento de Quimica Biologica, Facultad de Ciencias Quimicas, Ciudad Universitaria, Córdoba CP 5000, Argentina
    Biophys J 88:2706-13. 2005
    ....
  9. doi request reprint Impact of membrane-anchored fluorescent probes on the mechanical properties of lipid bilayers
    Hélène Bouvrais
    Department of Physics and Chemistry, MEMPHYS, Center for Biomembrane Physics, University of Southern Denmark, Denmark
    Biochim Biophys Acta 1798:1333-7. 2010
    ....
  10. doi request reprint Texture of lipid bilayer domains
    Uffe Bernchou
    Department of Physics and Chemistry, MEMPHYS Center for Biomembrane Physics, University of Southern Denmark, Campusvej 55, DK 5230 Odense M, Denmark
    J Am Chem Soc 131:14130-1. 2009
    ..The results show that although the gel domains have heterogeneous texture, the membrane phase state does not show spatial variation within each domain...
  11. pmc Direct visualization of membrane leakage induced by the antibiotic peptides: maculatin, citropin, and aurein
    Ernesto E Ambroggio
    CIQUIBIC CONICET, Departamento de Quimica Biologica, Facultad de Ciencias Quimicas, Ciudad Universitaria, Cordoba, Argentina
    Biophys J 89:1874-81. 2005
    ..As observed for maculatin, the lytic action of Maculatin-Ala and maculatin-Gly is in keeping with the formation of pore-like structures at the membrane independently of lipid composition...
  12. doi request reprint A method for analysis of lipid vesicle domain structure from confocal image data
    Peter Husen
    Department of Physics and Chemistry, MEMPHYS Centre for Biomembrane Physics, University of Southern Denmark, Campusvej 55, 5230, Odense, Denmark
    Eur Biophys J 41:161-75. 2012
    ..The analysis allows for investigation of the morphology and size distribution of domains on the surface...
  13. ncbi request reprint Thermotropic behavior of lipid mixtures studied at the level of single vesicles: giant unilamellar vesicles and two-photon excitation fluorescence microscopy
    Luis A Bagatolli
    Center for Biomembrane Physics, Department of Biochemistry and Molecular Biology, Campusvej 55, DK 5230 Odense M, Denmark
    Methods Enzymol 367:233-53. 2003
  14. pmc Lipid lateral organization on giant unilamellar vesicles containing lipopolysaccharides
    Jakubs Kubiak
    Membrane Biophysics and Biophotonics Group MEMPHYS Center for Biomembrane Physics, University of Southern Denmark, Odense, Denmark
    Biophys J 100:978-86. 2011
    ..Our results indicate that LPSs can cluster into gel-like domains in these bacterial model membranes, and that the size of these domains depends on the chemical structure and concentration of the LPSs...
  15. ncbi request reprint Structure of spin-coated lipid films and domain formation in supported membranes formed by hydration
    Adam Cohen Simonsen
    MEMPHYS Center for Biomembrane Physics, Physics Department, University of Southern Denmark, Campusvej 55, 5230 Odense M, Denmark
    Langmuir 20:9720-8. 2004
    ..It is further demonstrated that supported membranes of binary lipid mixtures prepared by this method exhibit gel-fluid domain coexistence in accordance with expectations from the phase diagrams...
  16. doi request reprint Pig skin structure and transdermal delivery of liposomes: a two photon microscopy study
    Dolores C Carrer
    Department of Biochemistry and Molecular Biology, Center for Biomembrane Physics, University of Southern Denmark, Odense, Denmark
    J Control Release 132:12-20. 2008
    ..The presence of charged lipids in the liposomes enhances size stability and thus the efficiency of penetration...
  17. pmc Giant unilamellar vesicles electroformed from native membranes and organic lipid mixtures under physiological conditions
    L Ruth Montes
    Unidad de Biofisica Centro Mixto CSIC UPV EHU, Departamento de Bioquimica, Universidad del Pais Vasco, 48080 Bilbao, Spain
    Biophys J 93:3548-54. 2007
    ....
  18. pmc Segregation of saturated chain lipids in pulmonary surfactant films and bilayers
    Kaushik Nag
    Department of Obstetrics and Gynecology, University of Western Ontario, London, Ontario N6A 5A5, Canada
    Biophys J 82:2041-51. 2002
    ....
  19. pmc Detergent-resistant, ceramide-enriched domains in sphingomyelin/ceramide bilayers
    Jesus Sot
    Unidad de Biofisica CSIC UPV EHU and Departamento de Bioquimica, Universidad del Pais Vasco, 48080 Bilbao, Spain
    Biophys J 90:903-14. 2006
    ..These observations may be relevant to the phenomena of sphingomyelinase-dependent signaling, generation of "raft platforms", and detergent-resistant cell membranes...
  20. ncbi request reprint Cholesterol rules: direct observation of the coexistence of two fluid phases in native pulmonary surfactant membranes at physiological temperatures
    Jorge Bernardino de la Serna
    Departmento de Bioquimica, Facultad de Biologia, Universidad Complutense, 28040 Madrid, Spain
    J Biol Chem 279:40715-22. 2004
    ..We suggest that the particular lipid composition of surfactant could be finely tuned to provide, under physiological conditions, a structural scaffold for surfactant proteins to act at appropriate local densities and lipid composition...
  21. ncbi request reprint Giant vesicles, Laurdan, and two-photon fluorescence microscopy: evidence of lipid lateral separation in bilayers
    Luis A Bagatolli
    Department of Physics, MEMPHYS Center for Biomembrane Physics, University of Southern Denmark, Odense
    Methods Enzymol 360:481-500. 2003
  22. pmc A two-photon view of an enzyme at work: Crotalus atrox venom PLA2 interaction with single-lipid and mixed-lipid giant unilamellar vesicles
    Susana A Sanchez
    Department of Physics, Laboratory for Fluorescence Dynamics, University of Illinois at Urbana Champaign, Urbana, Illinois 61801, USA
    Biophys J 82:2232-43. 2002
    ..These studies emphasize the importance of lateral packing of the lipids in C. atrox sPLA2 enzymatic hydrolysis of a membrane surface...
  23. pmc Ceramide-enriched membrane domains in red blood cells and the mechanism of sphingomyelinase-induced hot-cold hemolysis
    L Ruth Montes
    Unidad de Biofisica Centro Mixto CSIC UPV EHU and Departamento de Bioquimica, Universidad del Pais Vasco, Aptdo 644, 48080 Bilbao, Spain
    Biochemistry 47:11222-30. 2008
    ..Finally, in liposomes composed of SM, PC, and cholesterol, which exhibit slow release of aqueous contents at 37 degrees C, addition of 10 mol % ceramide and transfer to 4 degrees C cause a large increase in the rate of solute efflux...
  24. ncbi request reprint Profilin binding to sub-micellar concentrations of phosphatidylinositol (4,5) bisphosphate and phosphatidylinositol (3,4,5) trisphosphate
    Pierre D J Moens
    School of Biological, Biomedical and Molecular Sciences, The University of New England, Armidale, NSW 2351 Australia
    Biochim Biophys Acta 1768:439-49. 2007
    ..Despite the low affinity for sub-micellar concentration of PI(4,5)P(2), profilin was shown to bind to giant unilamellar vesicles in presence of 0.5% mole fraction of PI(4,5)P(2) The implications of these findings are discussed...
  25. ncbi request reprint Energy-independent translocation of cell-penetrating peptides occurs without formation of pores. A biophysical study with pep-1
    Sónia Troeira Henriques
    Centro de Quimica e Bioquimica, Faculdade de Ciencias da Universidade de Lisboa, Campo Grande, Lisboa, Portugal
    Mol Membr Biol 24:282-93. 2007
    ..A peptide-lipid structure is probably formed during peptide partition, which favours peptide translocation...