Research Topics
| Morten AndersenSummaryAffiliation: University of Southern Denmark Country: Denmark Publications
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Detail Information
Publications
How conducting a clinical trial affects physicians' guideline adherence and drug preferencesMorten Andersen
Research Unit for General Practice, University of Southern Denmark, Odense, Denmark
JAMA 295:2759-64. 2006..General practitioners are frequently involved in clinical trials sponsored by pharmaceutical companies but the effects of participation on their prescribing patterns have not been evaluated...
Is it possible to measure prescribing quality using only prescription data?Morten Andersen
Research Unit for General Practice, University of Southern Denmark, Odense C
Basic Clin Pharmacol Toxicol 98:314-9. 2006..Furthermore, the statistical and epidemiological properties of prescribing quality indicators need more attention...
Risk of stroke associated with nonsteroidal anti-inflammatory drugs: a nested case-control studySøren Bak
Department of Epidemiology, Institute of Public Health, University of Southern Denmark, Odense, Denmark
Stroke 34:379-86. 2003..We performed a population-based case-control study to estimate the risk of intracerebral hemorrhage, subarachnoid hemorrhage, and ischemic stroke in users of NSAIDs...
Use of opioids in a Danish population-based cohort of cancer patientsLene Jarlbaek
Research Unit of Clinical Pharmacology, Institute of Public Health, University of Southern Denmark, Odense, Denmark
J Pain Symptom Manage 29:336-43. 2005..Increased awareness towards pain treatment, with earlier initiation of opioid treatment and higher doses to the cancer patients, could be major explanations for the increase in the cancer patients' use of opioids...
Analysing duration of episodes of pharmacological care: an example of antidepressant use in Danish general practiceAnthony Gichangi
Department of Statistics, University of Southern Denmark, DK 5000 Odense C, Denmark
Pharmacoepidemiol Drug Saf 15:167-77. 2006....
Exposure to antiepileptic drugs and the risk of hip fracture: a case-control studyIoannis Tsiropoulos
Department of Neurology, Odense University Hospital, Odense, Denmark
Epilepsia 49:2092-9. 2008..To investigate whether the use of antiepileptic drugs (AEDs) increases the risk of hip fracture...
Promotional methods used by representatives of drug companies: a prospective survey in general practiceJesper Schramm
Research Unit for General Practice, University of Southern Denmark, Odense, Denmark
Scand J Prim Health Care 25:93-7. 2007..To examine the extent and composition of pharmaceutical industry representatives' marketing techniques with a particular focus on drug sampling in relation to drug age...
Do statins protect against upper gastrointestinal bleeding?Sinem Ezgi Gulmez
Research Unit of Clinical Pharmacology, University of Southern Denmark, Odense, Denmark
Br J Clin Pharmacol 67:460-5. 2009..We aimed to evaluate the effect of statin use on acute nonvariceal UGB alone or in combinations with low-dose aspirin and other antithrombotic drugs...
The impact of ageing and changing utilization patterns on future cardiovascular drug expenditure: a pharmacoepidemiological projection approachHelle Wallach Kildemoes
Research Unit for General Practice, Institute of Public Health, University of Southern Denmark, Odense, Denmark
Pharmacoepidemiol Drug Saf 19:1276-86. 2010..To develop a method for projecting the impact of ageing and changing drug utilization patterns on future drug expenditure...
Impact of socioeconomic status on the use of inhaled corticosteroids in young adult asthmaticsJesper Rømhild Davidsen
University of Southern Denmark, Faculty of Health Sciences, Institute of Public Health, Research Unit of General Practice, J B Winsløws Vej 9A, DK 5000 Odense C, Denmark
Respir Med 105:683-90. 2011....
Cancer patients' first treatment episode with opioids: a pharmaco-epidemiological perspectiveLene Jarlbaek
Research Unit of Clinical Pharmacology, Institute of Public Health, University of Southern Denmark, Winsloewparken 19, 5000, Odense C, Denmark
Support Care Cancer 14:340-7. 2006..The factors underlying the choice of opioids for cancer patients in primary care are largely unknown. Our aim was to describe cancer patients' first treatment episode with opioids in relation to disease characteristics and clinical course...
Driving forces behind increasing cardiovascular drug utilization: a dynamic pharmacoepidemiological modelHelle Wallach Kildemoes
Research Unit for General Practice, Institute of Public Health, University of Southern Denmark, Odense, Denmark
Br J Clin Pharmacol 66:885-95. 2008..To investigate the driving forces behind increasing utilization of cardiovascular drugs...
Impact of pharmaceutical representative visits on GPs' drug preferencesJens Søndergaard
Research Unit for General Practice, Institute of Public Health, University of Southern Denmark, J B Winsløws Vej 9A, Odense C DK 5000, Denmark
Fam Pract 26:204-9. 2009..Pharmaceutical representative visits are believed to have substantial impact, but the effects on prescribing patterns have not been systematically evaluated...
Cancer risk in long-term users of valproate: a population-based case-control studyJesper Hallas
Research Unit of Clinical Pharmacology, University of Southern Denmark, Odense C, Denmark
Cancer Epidemiol Biomarkers Prev 18:1714-9. 2009..We undertook this case-control study to clarify whether long-term users of valproate had a reduced cancer incidence. If so, it would support HDAC inhibition as a pharmacologic principle in chemoprevention...
Cardiovascular drugs and the risk of suicide: a nested case-control studyTorbjörn Callréus
Institute of Public Health, Research Unit of Clinical Pharmacology, University of Southern Denmark, J B Winsloews Vej 9A, 5000, Odense C, Denmark
Eur J Clin Pharmacol 63:591-6. 2007..In this study, we investigated the possible association between the use of cardiovascular drugs and suicide using population-based register data...
Does the early adopter of drugs exist? A population-based study of general practitioners' prescribing of new drugsTorben Dybdahl
Research Unit of General Practice, Institute of Public Health, University of Southern Denmark, Winsløwparken 19, 3rd, 5000, Odense C, Denmark
Eur J Clin Pharmacol 60:667-72. 2004..To analyse associations between indicators for adoption of new drugs and to test the hypothesis that physicians' early adoption of new drugs is a personal trait independent of drug groups...
On the crest of a wave: Danish prevalence of hospitalisation-required COPD 2002-2009Jesper Lykkegaard
Research Unit of General Practice, Institute of Public Health, University of Southern Denmark, J B Winsløws Vej 9A, DK 5000 Odense C, Denmark
Respir Med 106:1396-403. 2012..Nevertheless, no solid estimates exist of trends in the prevalence of this condition. This study aimed to investigate age- and sex-specific trends in the prevalence of hospitalisation-required COPD...
Factor analysis improves the selection of prescribing indicatorsHanne Marie Skyggedal Rasmussen
Research Unit for General Practice, Institute of Public Health, University of Southern Denmark, Odense, , DK-5000, Odense, Denmark
Eur J Clin Pharmacol 62:953-8. 2006..CONCLUSION: Correlation and factor analysis is a feasible method that assists the selection of indicators and gives better insight into prescribing patterns...
Factors influencing GPs' choice between drugs in a therapeutic drug group. A qualitative studyAllan Buusman
Research Unit for General Practice, Institute of Public Health, University of Southern Denmark, Odense, Denmark
Scand J Prim Health Care 25:208-13. 2007..To explore how GPs choose between drugs in a therapeutic drug group...
Use of a prescribed ephedrine/caffeine combination and the risk of serious cardiovascular events: a registry-based case-crossover studyJesper Hallas
Department of Clinical Pharmacology, Faculty of Health Sciences, University of Southern Denmark, DK 5000 Odense C, Denmark
Am J Epidemiol 168:966-73. 2008..Prescribed ephedrine/caffeine was not associated with a substantially increased risk of adverse cardiovascular outcomes in this study...
Detailed postal feedback about prescribing to asthma patients combined with a guideline statement showed no impact: a randomised controlled trialJens Søndergaard
Research Unit of Clinical Pharmacology, Institute of Public Health, University of Southern Denmark, Odense University, Odense, Denmark
Eur J Clin Pharmacol 58:127-32. 2002..To evaluate the effects of postal feedback with clinically relevant data on general practitioners' prescribing compared with feedback with aggregate data on prescribing patterns of asthma drugs...
Mailed prescriber feedback in addition to a clinical guideline has no impact: a randomised, controlled trialJens Søndergaard
Research Unit of General Practice, Institute of Public Health, University of Southern Denmark, Odense C
Scand J Prim Health Care 21:47-51. 2003..To evaluate the impact of feedback on the prescribing of antibiotics supplementary to clinical guidelines in the treatment of respiratory tract infections...
Cancer patients' share in a population's use of opioids. A linkage study between a prescription database and the Danish Cancer RegistryLene Jarlbaek
The Research Unit of General Practice, Institute of Public Health, University of Southern Denmark-Odense, Odense, Denmark
J Pain Symptom Manage 27:36-43. 2004..Cancer patients' consumption of strong opioids increased dramatically in 1996-1997, almost accounting for the entire increase in the whole population's consumption of strong opioids...
Insufficient use of lipid-lowering drugs and measurement of serum cholesterol among patients with a history of myocardial infarctionJohn Larsen
Department of Clinical Pharmacology, University of Southern Denmark, Odense, Denmark
J Cardiovasc Risk 10:61-4. 2003..However, intensity of the use of these drugs is low. The aim of this linkage study was to analyse the use of serum cholesterol measurements and LLDs among patients with a history of myocardial infarction (MI) in a Danish population...
All Danish first-time COPD hospitalisations 2002-2008: incidence, outcome, patients, and careJesper Lykkegaard
Research Unit of General Practice, Institute of Public Health, University of Southern Denmark, J B Winsløws Vej 9A, 1, DK 5000 Odense C, Denmark
Respir Med 106:549-56. 2012....
General practitioners' adoption of new drugs and previous prescribing of drugs belonging to the same therapeutic class: a pharmacoepidemiological studyTorben Dybdahl
Research Unit of General Practice, Institute of Public Health, University of Southern Denmark, , DK-5000 Odense, Denmark
Br J Clin Pharmacol 60:526-33. 2005..CONCLUSION: There is no consistent association between GPs' level of drug prescribing and their adoption of new drugs of the same therapeutic group...
Antibiotics active against Chlamydia do not reduce the risk of myocardial infarctionLars Bjerrum
Research Unit of General Practice, University of Southern Denmark, J B Winslows Vej 9, 5000, Odense C, Denmark
Eur J Clin Pharmacol 62:43-9. 2006..We investigated if past use of antibiotics active against CP is associated with a decreased risk of developing MI...
Adverse events with use of antiepileptic drugs: a prescription and event symmetry analysisIoannis Tsiropoulos
Department of Neurology, Odense University Hospital, Odense C, Denmark
Pharmacoepidemiol Drug Saf 18:483-91. 2009..To assess adverse events with use of antiepileptic drugs (AEDs) by the method of sequence symmetry analysis...
General practitioners choose within a narrow range of drugs when initiating new treatments: a cohort study of cardiovascular drug formulariesAllan Buusman
Research Unit of General Practice, University of Southern Denmark, J B Winsløws Vej 9, 5000 Odense C, Denmark
Eur J Clin Pharmacol 61:651-6. 2005....
Why has postal prescriber feedback no substantial impact on general practitioners' prescribing practice? A qualitative studyJens Søndergaard
Research Unit of Clinical Pharmacology, University of Southern Denmark, Odense University, Denmark
Eur J Clin Pharmacol 58:133-6. 2002..To better understand the reasons for lack of impact of sending feedback on prescribing pattern to general practitioners (GPs)...
Intensive community pharmacy intervention had little impact on triptan consumption: a randomized controlled trialJens Søndergaard
Research Unit for General Practice, University of Aarhus, Aarhus, Denmark
Scand J Prim Health Care 24:16-21. 2006..To evaluate the impact of an intensive pharmaceutical care campaign targeting inappropriate use of triptans...
Long term use of drugs affecting the renin-angiotensin system and the risk of cancer: a population-based case-control studyJesper Hallas
Research Unit of Clinical Pharmacology, University of Southern Denmark, Odense C, Denmark
Br J Clin Pharmacol 74:180-8. 2012..A recent meta-analysis has suggested an increased risk of cancer among users of angiotensin receptor blockers...
Increased use of inhaled corticosteroids among young Danish adult asthmatics: an observational studyJesper Rømhild Davidsen
Research Unit for General Practice, Institute of Public Health, University of Southern Denmark, J B Winsløws Vej 9A, Odense C, Denmark
Respir Med 104:1817-24. 2010..This population-based longitudinal study aimed to investigate trends in use of inhaled corticosteroids (ICS) and determinants of ICS use in young Danish adults with asthma...
Narrow and wide prescribers among general practitioners: a cohort study of drug formularies used for new treatmentsAllan Buusman
Research Unit for General Practice, University of Southern Denmark, J B Winsløws Vej 9 A, 5000, Odense C, Denmark
Eur J Clin Pharmacol 62:577-83. 2006....
General practitioners prefer prescribing indicators based on detailed information on individual patients: a Delphi studyHanne M S Rasmussen
Research Unit of General Practice, Institute of Public Health, University of Southern Denmark, Odense, Winsløwparken 19, 3, DK 5000, Odense, Denmark
Eur J Clin Pharmacol 61:237-41. 2005..To assess the face validity of both simple and advanced quality indicators for prescribing in general practice...
Exposure to potential drug interactions in primary health careLars Bjerrum
Research Unit of General Practice, University of Southern Denmark, Odense
Scand J Prim Health Care 21:153-8. 2003..To analyse the prevalence of potential drug interactions, and to identify patients particularly prone to drug interaction...
Use of single and combined antithrombotic therapy and risk of serious upper gastrointestinal bleeding: population based case-control studyJesper Hallas
Department of Clinical Pharmacology, IST, Syddansk Universitet, 5000 Odense, Denmark
BMJ 333:726. 2006....
[Drug marketing: methods, effect and regulation]Jens Søndergaard
Forskningsenheden for Almen Medicin, Institut for Sundhedstjenesteforskning, Syddansk Universitet, DK 5000 Odense C
Ugeskr Laeger 171:778-80. 2009..It has been shown that this interaction influences physicians' prescriptions inappropriately. As the interaction is inevitable, it should be further addressed how this interaction may be regulated to minimize non-rational prescribing...
[Frequent drug interactions in general practice]Lars Bjerrum
Syddansk Universitet, Forskningsenheden for Almen Praksis
Ugeskr Laeger 166:3401-4. 2004
[Rising prevalence and decreasing mortality of diabetes in the county of Funen]Henrik Støvring
Syddansk Universitet, Forskningsenheden for Almen Medicin
Ugeskr Laeger 166:1905-7. 2004
Spironolactone use and the risk of upper gastrointestinal bleeding: a population-based case-control studySinem E Gulmez
Research Unit of Clinical Pharmacology, Institute of Public Health, University of Southern Denmark, Odense, Denmark
Br J Clin Pharmacol 66:294-9. 2008..Recent studies have suggested an increased risk of upper gastrointestinal bleeding (UGB) in spironolactone users. The aim was to confirm the association, identify the risk factors and quantify the absolute risk...
The impact of population ageing on future Danish drug expenditureHelle Wallach Kildemoes
Institute of Public Health, Research Unit of Health Economics, University of Southern Denmark, Winsløws Vej 9, DK 5000 Odense C, Denmark
Health Policy 75:298-311. 2006....
Rising prevalence of diabetes: evidence from a Danish pharmaco-epidemiological databaseHenrik Støvring
Research Unit of General Practice, University of Southern Denmark, DK 5000, Odense, Denmark
Lancet 362:537-8. 2003..Future research into the causes of rising diabetes prevalence should take this fall in mortality into account to avoid incorrect conclusions about the relation between western lifestyle and the growing number of diabetics...
Hyponatremia in elderly patients treated with desmopressin for nocturia: a review of a case seriesTorbjörn Callréus
Research Unit of Clinical Pharmacology, Institute of Public Health, IPH, University of Southern Denmark, Winslowparken 19, 3rd Floor, 5000 Odense C, Denmark
Eur J Clin Pharmacol 61:281-4. 2005..In order to identify factors associated with an increased risk of hyponatremia in elderly patients treated with dDAVP for nocturia, we analysed spontaneous reports accrued from clinical practice in Denmark and Sweden...
High persistence of statin use in a Danish population: compliance study 1993-1998John Larsen
Research Unit of General Practice and Department of Clinical Pharmacology, University of Southern Denmark, Odense University, Odense, Denmark
Br J Clin Pharmacol 53:375-8. 2002..The aim of this study was to describe compliance with statin treatment by analysing prescription patterns on an individual level in a population-based prescription database over a 6 year period...
Selective serotonin reuptake inhibitors and the risk of stroke: a population-based case-control studySøren Bak
Departments of Epidemiology, Institute of Public Health, University of Southern Denmark, Odense, Denmark
Stroke 33:1465-73. 2002..We used population-based data to estimate the risk of hemorrhagic and ischemic stroke in users of SSRIs...
The danish model for improvement of diabetes care in general practice: impact of automated collection and feedback of patient dataHenrik Schroll
The Danish Quality Unit of General Practice, Institute of Public Health, University of Southern Denmark, 5000 Odense, Denmark
Int J Family Med 2012:208123. 2012..Due to lack of a control group, we are, however, not able to say if the drop in the proportion of uncontrolled cases is a result of participation in collection of electronic data and feedback alone...
A randomized trial of laypersons' perception of the benefit of osteoporosis therapy: number needed to treat versus postponement of hip fracturePalle Mark Christensen
Research Unit of Clinical Pharmacology, Institute of Public Health, University of Southern Denmark, Winsloewparken 19, 5000 Odense C, Denmark
Clin Ther 25:2575-85. 2003..An alternative to such risk-based measures is postponement of an adverse outcome (eg, hip fracture in the case of osteoporosis)...
[Drug prescription research in general practice. The Danish Society of General Medicine]Jens Søndergaard
Ugeskr Laeger 169:1095. 2007
Maternal vaginal microflora during pregnancy and the risk of asthma hospitalization and use of antiasthma medication in early childhoodChristine Stabell Benn
Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen, Denmark
J Allergy Clin Immunol 110:72-7. 2002..7; 95% CI, 1.1-2.6) were associated with asthma during the fifth year of life. CONCLUSION: The composition of the maternal vaginal micro-flora might be associated with wheezing and asthma in the offspring up to 5 years of age...
Statin use and age at death: evidence of a flawed analysisHenrik Støvring
Am J Cardiol 99:1181-2; author reply 1182. 2007
Problems in collecting comparable national drug use data in Europe: the example of antibacterialsMarit Rønning
WHO Collaborating Centre for Drug Statistics Methodology, c o Norwegian Institute of Public Health, P O Box 4404 Nydalen, 0403, Oslo, Norway
Eur J Clin Pharmacol 58:843-9. 2003..To describe the methodological problems in collecting retrospectively comparable data on drug use and to compare the use of antibacterials in some European countries...
Antihypertensive medication and the risk of acute pancreatitis: the European case-control study on drug-induced acute pancreatitis (EDIP)Ingo A Eland
Department of Internal Medicine, Pharmacoepidemiology Unit, Erasmus MC, Rotterdam, The Netherlands
Scand J Gastroenterol 41:1484-90. 2006..We quantified the risk of acute pancreatitis associated with the use of antihypertensive medication in the European study on drug-induced acute pancreatitis (EDIP)...
Patterns of antibiotic use in the community in DenmarkMark Muscat
National Centre of Antimicrobials and Infection Control, Statens Serum Institut, Copenhagen, Denmark
Scand J Infect Dis 38:597-603. 2006..While the existing legal framework preventing over-the-counter dispensation of antibiotics must be maintained, our results show that, in Denmark, interventions to optimize antibiotic use should primarily focus on the prescribers...
Tamoxifen as prophylaxis for prevention of gynaecomastia and breast pain associated with bicalutamide 150 mg monotherapy in patients with prostate cancer: a randomised, placebo-controlled, dose-response studyYves Fradet
Centre de Recherche, Chuq Hotel Dieu de Quebec, Quebec, PQ, Canada
Eur Urol 52:106-14. 2007..To define the optimum tamoxifen dose for reducing bicalutamide (CASODEX) 150 mg monotherapy-induced breast events (ie, gynaecomastia or breast pain or both) without compromising disease control...
Efficacy of sildenafil citrate (Viagra) in men with premature ejaculationChris G McMahon
Australian Centre for Sexual Health, Sydney, Australia
J Sex Med 2:368-75. 2005....
Current controversies in pharmacoepidemiologyJesper Hallas
Basic Clin Pharmacol Toxicol 98:235. 2006
