Helle R Andersen

Summary

Affiliation: University of Southern Denmark
Country: Denmark

Publications

  1. pmc Paraoxonase 1 polymorphism and prenatal pesticide exposure associated with adverse cardiovascular risk profiles at school age
    Helle R Andersen
    Institute of Public Health, University of Southern Denmark, Odense, Denmark
    PLoS ONE 7:e36830. 2012
  2. pmc The risk of cryptorchidism among sons of women working in horticulture in Denmark: a cohort study
    Pernille Gabel
    Danish Ramazzini Center, Department of Occupational Medicine, Aarhus University Hospital, Aarhus, Denmark
    Environ Health 10:100. 2011
  3. pmc Potential developmental neurotoxicity of pesticides used in Europe
    Marina Bjørling-Poulsen
    Department of Environmental Medicine, University of Southern Denmark, Winslowparken 17, 5000 Odense, Denmark
    Environ Health 7:50. 2008
  4. pmc Assessment of xenoestrogenic exposure by a biomarker approach: application of the E-Screen bioassay to determine estrogenic response of serum extracts
    Thomas Høj Rasmussen
    Department of Environmental Medicine, Institute of Public Health, University of Southern Denmark, Odense, Denmark
    Environ Health 2:12. 2003
  5. pmc Xeno-oestrogenic activity in serum as marker of occupational pesticide exposure
    Helle Raun Andersen
    Institute of Public Health, Department of Environmental Medicine, University of Southern Denmark, Odense, Denmark
    Occup Environ Med 64:708-14. 2007
  6. pmc Impaired reproductive development in sons of women occupationally exposed to pesticides during pregnancy
    Helle R Andersen
    Institute of Public Health, Department of Environmental Medicine, University of Southern Denmark, Odense, Denmark
    Environ Health Perspect 116:566-72. 2008
  7. ncbi request reprint Estrogenic effects in vitro and in vivo of the fungicide fenarimol
    Helle Raun Andersen
    Department of Environmental Medicine, Institute of Public Health, University of Southern Denmark, Winsløwparken 17, DK 5000 Odense C, Denmark
    Toxicol Lett 163:142-52. 2006
  8. pmc Association between prenatal polychlorinated biphenyl exposure and obesity development at ages 5 and 7 y: a prospective cohort study of 656 children from the Faroe Islands
    Jeanett L Tang-Péronard
    Department of Environmental Medicine, Institute of Public Health, University of Southern Denmark, Odense, Denmark JLT P, HRA, PG, and TKJ the Research Unit for Dietary Studies, Institute of Preventive Medicine, Copenhagen University Hospitals, Frederiksberg, Denmark JLT P and BLH the National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark BLH the Boden Institute of Obesity, Nutrition, Exercise and Eating Disorders, Sydney Medical School, Sydney, Australia BLH the Department of Occupational Medicine and Public Health, Torshavn, Faroe Islands US and the Department of Environmental Medicine, Faroese Hospital System, Torshavn, Faroe Islands PW
    Am J Clin Nutr 99:5-13. 2014
  9. doi request reprint Endocrine disrupting effects in vitro of conazole antifungals used as pesticides and pharmaceuticals
    Mia B Kjærstad
    Department of Environmental Medicine, Institute of Public Health, University of Southern Denmark, JB Winsløwsvej 17, Odense C, Denmark
    Reprod Toxicol 30:573-82. 2010
  10. doi request reprint Systemic uptake of miconazole during vaginal suppository use and effect on CYP1A2 and CYP3A4 associated enzyme activities in women
    Mia Birkhøj Kjærstad
    Department of Environmental Medicine, Institute of Public Health, University of Southern Denmark, JB Winsløwsvej 17, Odense C, Denmark
    Eur J Clin Pharmacol 66:1189-97. 2010

Collaborators

Detail Information

Publications16

  1. pmc Paraoxonase 1 polymorphism and prenatal pesticide exposure associated with adverse cardiovascular risk profiles at school age
    Helle R Andersen
    Institute of Public Health, University of Southern Denmark, Odense, Denmark
    PLoS ONE 7:e36830. 2012
    ..We explored if the PON1 Q192R genotype affects cardiovascular risk factors in school-age children prenatally exposed to pesticides...
  2. pmc The risk of cryptorchidism among sons of women working in horticulture in Denmark: a cohort study
    Pernille Gabel
    Danish Ramazzini Center, Department of Occupational Medicine, Aarhus University Hospital, Aarhus, Denmark
    Environ Health 10:100. 2011
    ..The main objective of the present study was to investigate whether pregnant women exposed to pesticides due to their work in horticulture experience excess risk of having sons with cryptorchidism...
  3. pmc Potential developmental neurotoxicity of pesticides used in Europe
    Marina Bjørling-Poulsen
    Department of Environmental Medicine, University of Southern Denmark, Winslowparken 17, 5000 Odense, Denmark
    Environ Health 7:50. 2008
    ..While awaiting more definite evidence, existing uncertainties should be considered in light of the need for precautionary action to protect brain development...
  4. pmc Assessment of xenoestrogenic exposure by a biomarker approach: application of the E-Screen bioassay to determine estrogenic response of serum extracts
    Thomas Høj Rasmussen
    Department of Environmental Medicine, Institute of Public Health, University of Southern Denmark, Odense, Denmark
    Environ Health 2:12. 2003
    ..Thus, analysis of mixtures allows evaluation of combined effects of chemicals each present at low concentrations...
  5. pmc Xeno-oestrogenic activity in serum as marker of occupational pesticide exposure
    Helle Raun Andersen
    Institute of Public Health, Department of Environmental Medicine, University of Southern Denmark, Odense, Denmark
    Occup Environ Med 64:708-14. 2007
    ..An increasing number of currently used pesticides are reported to possess oestrogen-like properties or to disturb the endocrine system in other ways...
  6. pmc Impaired reproductive development in sons of women occupationally exposed to pesticides during pregnancy
    Helle R Andersen
    Institute of Public Health, Department of Environmental Medicine, University of Southern Denmark, Odense, Denmark
    Environ Health Perspect 116:566-72. 2008
    ..The aim of this prospective study was to investigate whether occupational pesticide exposure during pregnancy causes adverse effects on the reproductive development in the male infants...
  7. ncbi request reprint Estrogenic effects in vitro and in vivo of the fungicide fenarimol
    Helle Raun Andersen
    Department of Environmental Medicine, Institute of Public Health, University of Southern Denmark, Winsløwparken 17, DK 5000 Odense C, Denmark
    Toxicol Lett 163:142-52. 2006
    ..The results indicates that fenarimol exhibits a dual effect being aromatase inhibitor at low concentrations and estrogenic at higher concentrations...
  8. pmc Association between prenatal polychlorinated biphenyl exposure and obesity development at ages 5 and 7 y: a prospective cohort study of 656 children from the Faroe Islands
    Jeanett L Tang-Péronard
    Department of Environmental Medicine, Institute of Public Health, University of Southern Denmark, Odense, Denmark JLT P, HRA, PG, and TKJ the Research Unit for Dietary Studies, Institute of Preventive Medicine, Copenhagen University Hospitals, Frederiksberg, Denmark JLT P and BLH the National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark BLH the Boden Institute of Obesity, Nutrition, Exercise and Eating Disorders, Sydney Medical School, Sydney, Australia BLH the Department of Occupational Medicine and Public Health, Torshavn, Faroe Islands US and the Department of Environmental Medicine, Faroese Hospital System, Torshavn, Faroe Islands PW
    Am J Clin Nutr 99:5-13. 2014
    ..Chemicals with endocrine-disrupting abilities may act as obesogens and interfere with the body's natural weight-control mechanisms, especially if exposure occurs during prenatal life...
  9. doi request reprint Endocrine disrupting effects in vitro of conazole antifungals used as pesticides and pharmaceuticals
    Mia B Kjærstad
    Department of Environmental Medicine, Institute of Public Health, University of Southern Denmark, JB Winsløwsvej 17, Odense C, Denmark
    Reprod Toxicol 30:573-82. 2010
    ..The triazoles were anti-androgenic in an androgen receptor reporter gene assay (epoxiconazole∼tebuconazole>propiconazole). This effect could not be evaluated for the pharmaceutical imidazoles due to cytotoxicity...
  10. doi request reprint Systemic uptake of miconazole during vaginal suppository use and effect on CYP1A2 and CYP3A4 associated enzyme activities in women
    Mia Birkhøj Kjærstad
    Department of Environmental Medicine, Institute of Public Health, University of Southern Denmark, JB Winsløwsvej 17, Odense C, Denmark
    Eur J Clin Pharmacol 66:1189-97. 2010
    ..To investigate if the ordinary use of a vaginal suppository containing miconazole results in systemic absorption that is sufficient to affect the activities of CYP1A2 and CYP3A4, which are major drug- and steroid-metabolising enzymes...
  11. ncbi request reprint Effects of currently used pesticides in assays for estrogenicity, androgenicity, and aromatase activity in vitro
    Helle Raun Andersen
    Environmental Medicine, Institute of Public Health, University of Southern Denmark, Odense, Winsløwparken 17, DK 5000 Odense C, Denmark
    Toxicol Appl Pharmacol 179:1-12. 2002
    ....
  12. ncbi request reprint Antiandrogenic effects in short-term in vivo studies of the fungicide fenarimol
    Anne Marie Vinggaard
    Department of Toxicology and Risk Assessment, Danish Institute for Food and Veterinary Research, Mørkhøj Bygade 19, DK 2860 Søborg, Denmark
    Toxicology 207:21-34. 2005
    ..Thus, it is suggested that fenarimol mediates its antiandrogenic effects at least partly via antagonism of androgen receptors...
  13. ncbi request reprint The combined antiandrogenic effects of five commonly used pesticides
    Mia Birkhøj
    Department of Toxicology and Risk Assessment, Danish Institute for Food and Veterinary Research, DK 2860 Søborg, Denmark
    Toxicol Appl Pharmacol 201:10-20. 2004
    ..Several pesticide-induced gene expression changes were observed, indicating that these are either very sensitive antiandrogenic end-points or that these changes are induced by a pathway not related to AR...
  14. ncbi request reprint Effects of currently used pesticides in the AhR-CALUX assay: comparison between the human TV101L and the rat H4IIE cell line
    Manhai Long
    Unit of Environmental Biotechnology, Department of Environmental and Occupational Medicine, University of Aarhus, Building 260, Vennelyst Boulevard 6, DK 8000 Aarhus C, Denmark
    Toxicology 194:77-93. 2003
    ..However, some pesticides (methiocarb, chlorothalonil, tribenuron-methyl, paclobutrazol and tolchlofos-methyl) elicited differential responses in the two cell lines...
  15. ncbi request reprint Antiandrogenic effects in vitro and in vivo of the fungicide prochloraz
    Anne Marie Vinggaard
    Institute of Food Safety and Nutrition, Danish Veterinary and Food Administration, Mørkhøj Bygade 19, DK 2860 Søborg, Denmark
    Toxicol Sci 69:344-53. 2002
    ..However, differential effects on levels of FSH, T(4), and TSH indicate that other modes of action apart from the pure AR antagonism might play a role in vivo...
  16. ncbi request reprint Prochloraz: an imidazole fungicide with multiple mechanisms of action
    Anne Marie Vinggaard
    Department of Toxicology and Risk Assessment, Danish Institute for Food and Veterinary Research, Søborg, Denmark
    Int J Androl 29:186-92. 2006
    ..That a fungicide with such effects is so widely used is a cause for concern, and its use should be reduced, thereby minimizing the risk of human exposure...