Bo Wiinberg

Summary

Affiliation: The Royal Veterinary and Agricultural University
Country: Denmark

Publications

  1. ncbi Validation of human recombinant tissue factor-activated thromboelastography on citrated whole blood from clinically healthy dogs
    Bo Wiinberg
    Department of Small Animal Clinical Sciences, The Royal Veterinary and Agricultural University, Copenhagen, Denmark
    Vet Clin Pathol 34:389-93. 2005
  2. ncbi Study on biological variation of haemostatic parameters in clinically healthy dogs
    Bo Wiinberg
    The Small Animal Hospital, Department of Small Animal Clinical Sciences, The Royal Veterinary and Agricultural University, Dyrlaegevej 16, Frederiksberg DK 1870, Denmark
    Vet J 174:62-8. 2007
  3. doi Development of a model based scoring system for diagnosis of canine disseminated intravascular coagulation with independent assessment of sensitivity and specificity
    Bo Wiinberg
    The Small Animal Hospital, Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Frederiksberg, Denmark
    Vet J 185:292-8. 2010
  4. ncbi Tissue factor activated thromboelastography correlates to clinical signs of bleeding in dogs
    Bo Wiinberg
    The Small Animal Hospital, Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Frederiksberg DK 1870, Denmark
    Vet J 179:121-9. 2009
  5. pmc Haemostatic alterations in a group of canine cancer patients are associated with cancer type and disease progression
    Eva B Andreasen
    Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark
    Acta Vet Scand 54:3. 2012
  6. doi The use of sequential organ failure assessment parameters in an awake porcine model of severe Staphylococcus aureus sepsis
    Karen E Soerensen
    Department of Veterinary Disease Biology, Faculty of Life Sciences, University of Copenhagen, Copenhagen, Denmark
    APMIS 120:909-21. 2012
  7. doi Prolonged activated prothromboplastin time and breed specific variation in haemostatic analytes in healthy adult Bernese Mountain dogs
    Lise Nikolic Nielsen
    Department of Small Animal Clinical Sciences, University of Copenhagen, Frederiksberg, Denmark
    Vet J 190:150-3. 2011
  8. ncbi In vitro heparinization of canine whole blood with low molecular weight heparin (dalteparin) significantly and dose-dependently prolongs heparinase-modified tissue factor-activated thromboelastography parameters and prothrombinase-induced clotting time
    Lisbeth R Jessen
    Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark
    Vet Clin Pathol 37:363-72. 2008
  9. doi Thrombin-activatable fibrinolysis inhibitor activity in healthy and diseased dogs
    Lisbeth R Jessen
    Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Copenhagen, Denmark
    Vet Clin Pathol 39:296-301. 2010
  10. pmc Canine specific ELISA for coagulation factor VII
    Tom Knudsen
    Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Copenhagen DK 1870, Denmark
    Vet J 190:352-8. 2011

Collaborators

Detail Information

Publications20

  1. ncbi Validation of human recombinant tissue factor-activated thromboelastography on citrated whole blood from clinically healthy dogs
    Bo Wiinberg
    Department of Small Animal Clinical Sciences, The Royal Veterinary and Agricultural University, Copenhagen, Denmark
    Vet Clin Pathol 34:389-93. 2005
    ..TEG has a largely unused potential in the diagnostic workup and monitoring of dogs with hemostatic disorders and it may be a valuable supplement to traditional coagulation parameters...
  2. ncbi Study on biological variation of haemostatic parameters in clinically healthy dogs
    Bo Wiinberg
    The Small Animal Hospital, Department of Small Animal Clinical Sciences, The Royal Veterinary and Agricultural University, Dyrlaegevej 16, Frederiksberg DK 1870, Denmark
    Vet J 174:62-8. 2007
    ..Analytical performance standards for imprecision were only met for one of the coagulation assays, whereas all TEG parameters except the alpha angle, alpha achieved this analytical goal...
  3. doi Development of a model based scoring system for diagnosis of canine disseminated intravascular coagulation with independent assessment of sensitivity and specificity
    Bo Wiinberg
    The Small Animal Hospital, Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Frederiksberg, Denmark
    Vet J 185:292-8. 2010
    ..3%, specificity 77.3%). Based on commonly used, plasma-based coagulation assays, it was possible to design an objective diagnostic scoring system for canine DIC with a high sensitivity and specificity...
  4. ncbi Tissue factor activated thromboelastography correlates to clinical signs of bleeding in dogs
    Bo Wiinberg
    The Small Animal Hospital, Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Frederiksberg DK 1870, Denmark
    Vet J 179:121-9. 2009
    ..The findings strongly suggest that TF- activated TEG may be of value in the workup of dogs suspected of having a haemostatic disorder...
  5. pmc Haemostatic alterations in a group of canine cancer patients are associated with cancer type and disease progression
    Eva B Andreasen
    Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark
    Acta Vet Scand 54:3. 2012
    ..The objective of the present study was to evaluate haemostatic variables of coagulation and fibrinolysis in a group of canine cancer patients, and to compare haemostatic changes to the cancer type and progression of disease...
  6. doi The use of sequential organ failure assessment parameters in an awake porcine model of severe Staphylococcus aureus sepsis
    Karen E Soerensen
    Department of Veterinary Disease Biology, Faculty of Life Sciences, University of Copenhagen, Copenhagen, Denmark
    APMIS 120:909-21. 2012
    ..Changes in SOFA parameters may in future porcine studies serve as a target for monitoring the effect of therapeutic intervention...
  7. doi Prolonged activated prothromboplastin time and breed specific variation in haemostatic analytes in healthy adult Bernese Mountain dogs
    Lise Nikolic Nielsen
    Department of Small Animal Clinical Sciences, University of Copenhagen, Frederiksberg, Denmark
    Vet J 190:150-3. 2011
    ..For aPTT the new RI was markedly different (0-100s). Whereas the new intervals for TEG (MA) and TEG (G) may be due to breed related biological variation, the cause of the prolonged RI for aPTT is at present uncertain...
  8. ncbi In vitro heparinization of canine whole blood with low molecular weight heparin (dalteparin) significantly and dose-dependently prolongs heparinase-modified tissue factor-activated thromboelastography parameters and prothrombinase-induced clotting time
    Lisbeth R Jessen
    Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark
    Vet Clin Pathol 37:363-72. 2008
    ..Low-molecular-weight heparin (LMWH) is being used increasingly in veterinary medicine for both treatment and prophylaxis of thromboembolic disease, but no predictable patient-side method exists to monitor its effect...
  9. doi Thrombin-activatable fibrinolysis inhibitor activity in healthy and diseased dogs
    Lisbeth R Jessen
    Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Copenhagen, Denmark
    Vet Clin Pathol 39:296-301. 2010
    ..TAFI activity in dogs has been described in experimental models, but not in dogs with spontaneous disease...
  10. pmc Canine specific ELISA for coagulation factor VII
    Tom Knudsen
    Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Copenhagen DK 1870, Denmark
    Vet J 190:352-8. 2011
    ..Together with activity based assays, such as FVII:C, the FVII:Ag ELISA should be valuable in the diagnosis of hereditary canine FVII deficiency...
  11. doi Evaluation of platelet aggregometry in dogs using the Multiplate platelet analyzer: impact of anticoagulant choice and assay duration
    Clara B Marschner
    Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark
    J Vet Emerg Crit Care (San Antonio) 22:107-15. 2012
    ..To investigate the performance of the Multiplate platelet function analyzer with regards to: (1) the use of 3 different anticoagulants (ie, citrate, hirudin, and heparin) and (2) the evaluation of optimal assay time...
  12. doi Diagnosis and treatment of platelet hyperactivity in relation to thrombosis in dogs and cats
    Bo Wiinberg
    Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, DK 1810 Frederiksberg, Denmark
    J Vet Emerg Crit Care (San Antonio) 22:42-58. 2012
    ..To review the mechanisms of platelet activation and options for diagnosing and treating platelet hyperactivity in relation to thrombosis in dogs and cats...
  13. pmc Thromboelastography results on citrated whole blood from clinically healthy cats depend on modes of activation
    Clara B Marschner
    Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen Denmark, Dyrlaegevej 16, Frederiksberg C, Denmark
    Acta Vet Scand 52:38. 2010
    ..The objective of the present study was to evaluate and compare three different TEG assays in healthy cats, in order to establish which assay may be best suited for TEG analyses in cats...
  14. doi Endogenous fibrinolytic potential in tissue-plasminogen activator-modified thromboelastography analysis is significantly decreased in dogs suffering from diseases predisposing to thrombosis
    Eva H Spodsberg
    Department of Clinical Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University Hospital for Companion Animals, University of Copenhagen, Frederiksberg C, Denmark
    Vet Clin Pathol 42:281-90. 2013
    ..Investigations into the potential of t-PA-modified TEG to monitor endogenous fibrinolytic potential are lacking in both healthy dogs and dogs with diseases predisposing to development of thrombosis...
  15. ncbi Endotoxin activity in whole blood measured by neutrophil chemiluminescence is applicable to canine whole blood
    Mads Kjelgaard-Hansen
    Department of Small Animal Sciences, Faculty of Life Sciences, University of Copenhagen, 3 Gronnegaardsvej, DK 1870 Frederiksberg C, Denmark
    Comp Immunol Microbiol Infect Dis 31:477-85. 2008
    ..The rapid patient-near assessment of endotoxin activity in canine blood should facilitate future studies on endotoxemia in both spontaneous disease and in experimental settings...
  16. doi Intravenous inoculation of Staphylococcus aureus in pigs induces severe sepsis as indicated by increased hypercoagulability and hepatic dysfunction
    Pall S Leifsson
    Department of Veterinary Disease Biology, Faculty of Life Sciences, University of Copenhagen, Copenhagen, Denmark
    FEMS Microbiol Lett 309:208-16. 2010
    ..The levels of serum aspartate aminotransferase and bilirubin were elevated at 24 and 36 h. In conclusion, sepsis and severe sepsis were induced as evidenced by dysfunction of the blood clotting system and the liver...
  17. doi Thromboelastography in veterinary medicine
    Bo Wiinberg
    The Small Animal Hospital, Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Frederiksberg, Denmark
    Semin Thromb Hemost 36:747-56. 2010
    ..TEG is already well established in veterinary medicine, and with the rapid dissemination of the technique currently taking place, we can expect to see a wide variety of interesting animal data published in the near future...
  18. doi Comparison of components of biological variation between 3 equine thromboelastography assays
    Sigrid Hyldahl Laursen
    Department of Large Animal Sciences, Faculty of Health and Medicine, University of Copenhagen, Tastrup, Denmark
    Vet Clin Pathol 42:443-50. 2013
    ..Such data may be obtained by nested analysis of repetitive standardized sampling of healthy individuals...
  19. ncbi Quantitative analysis of inflammatory and immune responses in dogs with gastritis and their relationship to Helicobacter spp. infection
    Bo Wiinberg
    Royal Veterinary and Agricultural University, Frederiksberg, Denmark
    J Vet Intern Med 19:4-14. 2005
    ..No significant associations between Helicobacter infection and proinflammatory cytokine expression, severity of gastritis, or differences in the pathogenicity of different Helicobacter spp. were found...
  20. pmc Evaluation of "Helicobacter heilmannii" subtypes in the gastric mucosas of cats and dogs
    Simon L Priestnall
    College of Veterinary Medicine, Cornell University, Ithaca, New York 14851, USA
    J Clin Microbiol 42:2144-51. 2004
    ..heilmannii" bacteria that are distinct from type 1 and from "H. suis." As "H. heilmannii" type 1 predominates in people, the zoonotic risk posed by dogs and cats is likely small...