Research Topics
| Bo WiinbergSummaryAffiliation: The Royal Veterinary and Agricultural University Country: Denmark Publications
| Collaborators
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Detail Information
Publications
Validation of human recombinant tissue factor-activated thromboelastography on citrated whole blood from clinically healthy dogsBo Wiinberg
Department of Small Animal Clinical Sciences, The Royal Veterinary and Agricultural University, Copenhagen, Denmark
Vet Clin Pathol 34:389-93. 2005..TEG has a largely unused potential in the diagnostic workup and monitoring of dogs with hemostatic disorders and it may be a valuable supplement to traditional coagulation parameters...
Development of a model based scoring system for diagnosis of canine disseminated intravascular coagulation with independent assessment of sensitivity and specificityBo Wiinberg
The Small Animal Hospital, Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Frederiksberg, Denmark
Vet J 185:292-8. 2010..3%, specificity 77.3%). Based on commonly used, plasma-based coagulation assays, it was possible to design an objective diagnostic scoring system for canine DIC with a high sensitivity and specificity...- Study on biological variation of haemostatic parameters in clinically healthy dogsBo Wiinberg
The Small Animal Hospital, Department of Small Animal Clinical Sciences, The Royal Veterinary and Agricultural University, Dyrlaegevej 16, Frederiksberg DK 1870, Denmark
Vet J 174:62-8. 2007..Analytical performance standards for imprecision were only met for one of the coagulation assays, whereas all TEG parameters except the alpha angle, alpha achieved this analytical goal... - Tissue factor activated thromboelastography correlates to clinical signs of bleeding in dogsBo Wiinberg
The Small Animal Hospital, Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Frederiksberg DK 1870, Denmark
Vet J 179:121-9. 2009..The findings strongly suggest that TF- activated TEG may be of value in the workup of dogs suspected of having a haemostatic disorder... 
Haemostatic alterations in a group of canine cancer patients are associated with cancer type and disease progressionEva B Andreasen
Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark
Acta Vet Scand 54:3. 2012..The objective of the present study was to evaluate haemostatic variables of coagulation and fibrinolysis in a group of canine cancer patients, and to compare haemostatic changes to the cancer type and progression of disease...- The use of sequential organ failure assessment parameters in an awake porcine model of severe Staphylococcus aureus sepsisKaren E Soerensen
Department of Veterinary Disease Biology, Faculty of Life Sciences, University of Copenhagen, Copenhagen, Denmark
APMIS 120:909-21. 2012..Changes in SOFA parameters may in future porcine studies serve as a target for monitoring the effect of therapeutic intervention... - Prolonged activated prothromboplastin time and breed specific variation in haemostatic analytes in healthy adult Bernese Mountain dogsLise Nikolic Nielsen
Department of Small Animal Clinical Sciences, University of Copenhagen, Frederiksberg, Denmark
Vet J 190:150-3. 2011..For aPTT the new RI was markedly different (0-100s). Whereas the new intervals for TEG (MA) and TEG (G) may be due to breed related biological variation, the cause of the prolonged RI for aPTT is at present uncertain... - In vitro heparinization of canine whole blood with low molecular weight heparin (dalteparin) significantly and dose-dependently prolongs heparinase-modified tissue factor-activated thromboelastography parameters and prothrombinase-induced clotting timeLisbeth R Jessen
Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark
Vet Clin Pathol 37:363-72. 2008..Low-molecular-weight heparin (LMWH) is being used increasingly in veterinary medicine for both treatment and prophylaxis of thromboembolic disease, but no predictable patient-side method exists to monitor its effect... - Thrombin-activatable fibrinolysis inhibitor activity in healthy and diseased dogsLisbeth R Jessen
Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Copenhagen, Denmark
Vet Clin Pathol 39:296-301. 2010..TAFI activity in dogs has been described in experimental models, but not in dogs with spontaneous disease... - Canine specific ELISA for coagulation factor VIITom Knudsen
Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Copenhagen DK 1870, Denmark
Vet J 190:352-8. 2011..Together with activity based assays, such as FVII:C, the FVII:Ag ELISA should be valuable in the diagnosis of hereditary canine FVII deficiency... - Thromboelastography results on citrated whole blood from clinically healthy cats depend on modes of activationClara B Marschner
Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen Denmark, Dyrlaegevej 16, Frederiksberg C, Denmark
Acta Vet Scand 52:38. 2010..The objective of the present study was to evaluate and compare three different TEG assays in healthy cats, in order to establish which assay may be best suited for TEG analyses in cats... - Intravenous inoculation of Staphylococcus aureus in pigs induces severe sepsis as indicated by increased hypercoagulability and hepatic dysfunctionPall S Leifsson
Department of Veterinary Disease Biology, Faculty of Life Sciences, University of Copenhagen, Copenhagen, Denmark
FEMS Microbiol Lett 309:208-16. 2010..The levels of serum aspartate aminotransferase and bilirubin were elevated at 24 and 36 h. In conclusion, sepsis and severe sepsis were induced as evidenced by dysfunction of the blood clotting system and the liver... - Endotoxin activity in whole blood measured by neutrophil chemiluminescence is applicable to canine whole bloodMads Kjelgaard-Hansen
Department of Small Animal Sciences, Faculty of Life Sciences, University of Copenhagen, 3 Gronnegaardsvej, DK 1870 Frederiksberg C, Denmark
Comp Immunol Microbiol Infect Dis 31:477-85. 2008..The rapid patient-near assessment of endotoxin activity in canine blood should facilitate future studies on endotoxemia in both spontaneous disease and in experimental settings... - Diagnosis and treatment of platelet hyperactivity in relation to thrombosis in dogs and catsBo Wiinberg
Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, DK 1810 Frederiksberg, Denmark
J Vet Emerg Crit Care (San Antonio) 22:42-58. 2012..To review the mechanisms of platelet activation and options for diagnosing and treating platelet hyperactivity in relation to thrombosis in dogs and cats... - Evaluation of platelet aggregometry in dogs using the Multiplate platelet analyzer: impact of anticoagulant choice and assay durationClara B Marschner
Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark
J Vet Emerg Crit Care (San Antonio) 22:107-15. 2012..To investigate the performance of the Multiplate platelet function analyzer with regards to: (1) the use of 3 different anticoagulants (ie, citrate, hirudin, and heparin) and (2) the evaluation of optimal assay time... - Thromboelastography in veterinary medicineBo Wiinberg
The Small Animal Hospital, Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Frederiksberg, Denmark
Semin Thromb Hemost 36:747-56. 2010..TEG is already well established in veterinary medicine, and with the rapid dissemination of the technique currently taking place, we can expect to see a wide variety of interesting animal data published in the near future... - Quantitative analysis of inflammatory and immune responses in dogs with gastritis and their relationship to Helicobacter spp. infectionBo Wiinberg
Royal Veterinary and Agricultural University, Frederiksberg, Denmark
J Vet Intern Med 19:4-14. 2005..No significant associations between Helicobacter infection and proinflammatory cytokine expression, severity of gastritis, or differences in the pathogenicity of different Helicobacter spp. were found... - Evaluation of "Helicobacter heilmannii" subtypes in the gastric mucosas of cats and dogsSimon L Priestnall
College of Veterinary Medicine, Cornell University, Ithaca, New York 14851, USA
J Clin Microbiol 42:2144-51. 2004..heilmannii" bacteria that are distinct from type 1 and from "H. suis." As "H. heilmannii" type 1 predominates in people, the zoonotic risk posed by dogs and cats is likely small...