Research Topics | Barbara Ann HalkierSummaryAffiliation: The Royal Veterinary and Agricultural University Country: Denmark Publications
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Publications
Biology and biochemistry of glucosinolatesBarbara Ann Halkier
Plant Biochemistry Laboratory, Department of Plant Biology, Royal Veterinary and Agricultural University, DK 1871 Frederiksberg C, Denmark
Annu Rev Plant Biol 57:303-33. 2006..This may enable us to more fully exploit the potential of these compounds in agriculture and medicine...- Composition and content of glucosinolates in developing Arabidopsis thalianaBent Larsen Petersen
Plant Biochemistry Laboratory, Department of Plant Biology, Royal Veterinary and Agricultural University, Frederiksberg C, Copenhagen, Denmark
Planta 214:562-71. 2002..This indicates that there is a continuous turnover of glucosinolates during development and not only upon tissue disruption... 
A complex interplay of three R2R3 MYB transcription factors determines the profile of aliphatic glucosinolates in ArabidopsisIda Elken Sønderby
Plant Biochemistry Laboratory, Villum Kann Rasmussen Research Centre for Pro Active Plants, and Plant Biochemistry Laboratory, Department of Plant Biology and Biotechnology, Faculty of Life Sciences, Copenhagen University, 1871 Frederiksberg C, Copenhagen, Denmark
Plant Physiol 153:348-63. 2010..Similar regulatory networks might exist in other secondary pathways...
Glucosinolate engineering identifies a gamma-glutamyl peptidaseFernando Geu-Flores
Plant Biochemistry Laboratory, Department of Plant Biology, Faculty of Life Sciences, University of Copenhagen, Frederiksberg, Denmark
Nat Chem Biol 5:575-7. 2009....- Towards engineering glucosinolates into non-cruciferous plantsFernando Geu-Flores
Plant Biochemistry Laboratory, VKR Research Centre Pro Active Plants, Department of Plant Biology and Biotechnology, Faculty of Life Sciences, University of Copenhagen, 40 Thorvaldsensvej, 1871, Frederiksberg C, Denmark
Planta 229:261-70. 2009..In summary, we transferred the last three steps of the benzylglucosinolate pathway to tobacco as a first step towards engineering glucosinolates into non-cruciferous plants... - Subclade of flavin-monooxygenases involved in aliphatic glucosinolate biosynthesisJing Li
Plant Biochemistry Laboratory, Department of Plant Biology and Villum Kann Rasmussen Research Centre for Pro Active Plants, Faculty of Life Sciences, University of Copenhagen, DK 1871 Frederiksberg C, Denmark
Plant Physiol 148:1721-33. 2008.... - A systems biology approach identifies a R2R3 MYB gene subfamily with distinct and overlapping functions in regulation of aliphatic glucosinolatesIda Elken Sønderby
Plant Biochemistry Laboratory, Department of Plant Biology, Center for Molecular Plant Physiology PlaCe, Faculty of Life Sciences, University of Copenhagen, Copenhagen, Denmark
PLoS ONE 2:e1322. 2007..Knowledge about the genes controlling glucosinolate regulation is limited. Here, we identify three R2R3 MYB transcription factors regulating aliphatic glucosinolate biosynthesis in Arabidopsis by combining several systems biology tools... - Production of the cancer-preventive glucoraphanin in tobaccoMichael Dalgaard Mikkelsen
University of Copenhagen, Faculty of Life Sciences, Department of Plant Biology, Plant Biochemistry Laboratory, VKR Research Centre for Pro Active Plants, 40 Thorvaldsensvej, DK 1871 Frederiksberg C, Copenhagen, Denmark
Mol Plant 3:751-9. 2010..Demonstrating the production of the high-value glucoraphanin in a heterologous host has great potential in the food and medicinal industry as a means to generate a stable, rich source of glucoraphanin for the benefit of human health... - Arabidopsis mutants in the C-S lyase of glucosinolate biosynthesis establish a critical role for indole-3-acetaldoxime in auxin homeostasisMichael Dalgaard Mikkelsen
Plant Biochemistry Laboratory, Department of Plant Biology, The Royal Veterinary and Agricultural University, Thorvaldsensvej 40, DK 1871 Frederiksberg C, Copenhagen, Denmark
Plant J 37:770-7. 2004..Our findings provide important insight to the critical role IAOx plays in auxin homeostasis as a key branching point between primary and secondary metabolism, and define a framework for further dissection of auxin biosynthesis... - CYP83A1 and CYP83B1, two nonredundant cytochrome P450 enzymes metabolizing oximes in the biosynthesis of glucosinolates in ArabidopsisPeter Naur
Plant Biochemistry Laboratory, Department of Chemistry, Center for Molecular Plant Physiology, The Royal Veterinary and Agricultural University, Thorvaldsensvej 40, DK 1871 Frederiksberg C, Denmark
Plant Physiol 133:63-72. 2003.... - Metabolic engineering of valine- and isoleucine-derived glucosinolates in Arabidopsis expressing CYP79D2 from CassavaMichael Dalgaard Mikkelsen
Plant Biochemistry Laboratory, Department of Plant Biology, The Royal Veterinary and Agricultural University, DK-1871 Frederiksberg C, Copenhagen, Denmark
Plant Physiol 131:773-9. 2003.... - Modulation of CYP79 genes and glucosinolate profiles in Arabidopsis by defense signaling pathwaysMichael Dalgaard Mikkelsen
Plant Biochemistry Laboratory, Department of Plant Biology, The Royal Veterinary and Agricultural University, Thorvaldsensvej 40, opgang 10, St, DK-1871 Frederiksberg C, Copenhagen, Denmark
Plant Physiol 131:298-308. 2003..Thus, different defense pathways activate subsets of biosynthetic enzymes, leading to the accumulation of specific glucosinolates... - Linking metabolic QTLs with network and cis-eQTLs controlling biosynthetic pathwaysAdam M Wentzell
Department of Plant Sciences, University of California Davis, Davis, California, USA
PLoS Genet 3:1687-701. 2007..This suggests that natural variation in transcripts may significantly impact phenotypic variation, but that natural variation in metabolites or their enzymatic loci can feed back to affect the transcripts... - Functional analysis of the tandem-duplicated P450 genes SPS/BUS/CYP79F1 and CYP79F2 in glucosinolate biosynthesis and plant development by Ds transposition-generated double mutantsTitima Tantikanjana
Department of Plant Biology and Agronomy, University of California, Davis, California 95616, USA
Plant Physiol 135:840-8. 2004..This study also provides further demonstration of how gluconisolate biosynthesis, regarded as secondary metabolism, is intricately linked with hormone homeostatis and hence with plant growth and development... - Altering glucosinolate profiles modulates disease resistance in plantsGünter Brader
Division of Genetics, Department of Biological and Environmental Sciences, Faculty of Biosciences, Viikki Biocenter, University of Helsinki, PO Box 56, FIN 00014 Helsinki, Finland
Plant J 46:758-67. 2006..Arabidopsis with modified GS profiles provide important tools for evaluating the biological effects of individual GSs and thereby show potential as biotechnological tools for the generation of plants with tailor-made disease resistance...