D R Witte

Summary

Affiliation: Steno Diabetes Center
Country: Denmark

Publications

  1. ncbi The effect of FOXA2 rs1209523 on glucose-related phenotypes and risk of type 2 diabetes in Danish individuals
    Karina Banasik
    The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health Sciences, University of Copenhagen, Denmark
    BMC Med Genet 13:10. 2012
  2. ncbi Studies of a genetic variant in HK1 in relation to quantitative metabolic traits and to the prevalence of type 2 diabetes
    Anette P Gjesing
    The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health Sciences, University of Copenhagen, Universitetsparken 1 3, 2100 Copenhagen, Denmark
    BMC Med Genet 12:99. 2011
  3. ncbi The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load
    Malene Hornbak
    Marie Krogh Center for Metabolic Research, Section of Metabolic Genetics, Faculty of Health Sciences, University of Copenhagen, Denmark
    BMC Med Genet 12:4. 2011
  4. ncbi Estimation of allele frequency and association mapping using next-generation sequencing data
    Su Yeon Kim
    Departments of Integrative Biology and Statistics, UC Berkeley, Berkeley, CA 94720, USA
    BMC Bioinformatics 12:231. 2011
  5. ncbi Performance of existing risk scores in screening for undiagnosed diabetes: an external validation study
    D R Witte
    Department of Epidemiology and Public Health, University College London, London, UK
    Diabet Med 27:46-53. 2010
  6. ncbi Differential relationship between physical activity and progression to diabetes by glucose tolerance status: the Inter99 Study
    S Engberg
    Steno Diabetes Center, 2820 Gentofte, Denmark
    Diabetologia 53:70-8. 2010
  7. ncbi Sex differences in glucose levels: a consequence of physiology or methodological convenience? The Inter99 study
    K Faerch
    Steno Diabetes Center, Niels Steensens Vej 2, DK 2820, Gentofte, Denmark
    Diabetologia 53:858-65. 2010
  8. ncbi Real-life glycaemic profiles in non-diabetic individuals with low fasting glucose and normal HbA1c: the A1C-Derived Average Glucose (ADAG) study
    R Borg
    Steno Diabetes Center, Niels Steensens vej 2 4, DK 2820 Gentofte, Denmark
    Diabetologia 53:1608-11. 2010
  9. ncbi Predictors of future fasting and 2-h post-OGTT plasma glucose levels in middle-aged men and women-the Inter99 study
    K Faerch
    Steno Diabetes Centre, Niels Steensens Vej 2, DK 2820 Gentofte, Denmark
    Diabet Med 26:377-83. 2009
  10. ncbi HbA₁(c) and mean blood glucose show stronger associations with cardiovascular disease risk factors than do postprandial glycaemia or glucose variability in persons with diabetes: the A1C-Derived Average Glucose (ADAG) study
    R Borg
    Steno Diabetes Center A S, Gentofte, Denmark
    Diabetologia 54:69-72. 2011

Collaborators

Detail Information

Publications16

  1. ncbi The effect of FOXA2 rs1209523 on glucose-related phenotypes and risk of type 2 diabetes in Danish individuals
    Karina Banasik
    The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health Sciences, University of Copenhagen, Denmark
    BMC Med Genet 13:10. 2012
    ..Secondly, we investigated whether rs1205923 in FOXA2 associated with other glucose-related phenotypes...
  2. ncbi Studies of a genetic variant in HK1 in relation to quantitative metabolic traits and to the prevalence of type 2 diabetes
    Anette P Gjesing
    The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health Sciences, University of Copenhagen, Universitetsparken 1 3, 2100 Copenhagen, Denmark
    BMC Med Genet 12:99. 2011
    ..Furthermore, our aim was to perform a type 2 diabetes case-control analysis and meta-analysis with two previous case-control studies...
  3. ncbi The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load
    Malene Hornbak
    Marie Krogh Center for Metabolic Research, Section of Metabolic Genetics, Faculty of Health Sciences, University of Copenhagen, Denmark
    BMC Med Genet 12:4. 2011
    ..We aimed to investigate whether the two variants associate with altered insulin release following an oral glucose load or with T2D...
  4. ncbi Estimation of allele frequency and association mapping using next-generation sequencing data
    Su Yeon Kim
    Departments of Integrative Biology and Statistics, UC Berkeley, Berkeley, CA 94720, USA
    BMC Bioinformatics 12:231. 2011
    ..g., < 15X). However, SNP calling and allele frequency estimation in such studies is associated with substantial statistical uncertainty because of varying coverage and high error rates...
  5. ncbi Performance of existing risk scores in screening for undiagnosed diabetes: an external validation study
    D R Witte
    Department of Epidemiology and Public Health, University College London, London, UK
    Diabet Med 27:46-53. 2010
    ..To compare the performance of nine published strategies for the selection of individuals prior to screening for undiagnosed diabetes...
  6. ncbi Differential relationship between physical activity and progression to diabetes by glucose tolerance status: the Inter99 Study
    S Engberg
    Steno Diabetes Center, 2820 Gentofte, Denmark
    Diabetologia 53:70-8. 2010
    ....
  7. ncbi Sex differences in glucose levels: a consequence of physiology or methodological convenience? The Inter99 study
    K Faerch
    Steno Diabetes Center, Niels Steensens Vej 2, DK 2820, Gentofte, Denmark
    Diabetologia 53:858-65. 2010
    ..Moreover, we aimed to study to what degree the newly suggested high-risk HbA(1c) criteria overlapped with the current OGTT-based criteria of glucose intolerance...
  8. ncbi Real-life glycaemic profiles in non-diabetic individuals with low fasting glucose and normal HbA1c: the A1C-Derived Average Glucose (ADAG) study
    R Borg
    Steno Diabetes Center, Niels Steensens vej 2 4, DK 2820 Gentofte, Denmark
    Diabetologia 53:1608-11. 2010
    ..Real-life glycaemic profiles of healthy individuals are poorly studied. Our aim was to analyse to what extent individuals without diabetes exceed OGTT thresholds for impaired glucose tolerance (IGT) and diabetes...
  9. ncbi Predictors of future fasting and 2-h post-OGTT plasma glucose levels in middle-aged men and women-the Inter99 study
    K Faerch
    Steno Diabetes Centre, Niels Steensens Vej 2, DK 2820 Gentofte, Denmark
    Diabet Med 26:377-83. 2009
    ..We studied whether risk factors predicting subtle elevations of FPG levels were different from those predicting elevations of 2hPG levels in men and women...
  10. ncbi HbA₁(c) and mean blood glucose show stronger associations with cardiovascular disease risk factors than do postprandial glycaemia or glucose variability in persons with diabetes: the A1C-Derived Average Glucose (ADAG) study
    R Borg
    Steno Diabetes Center A S, Gentofte, Denmark
    Diabetologia 54:69-72. 2011
    ..We examined the association between various indices of glycaemia measured during everyday activities and metabolic CVD risk factors in the A1C-Derived Average Glucose (ADAG) study...
  11. ncbi Low birthweight and premature birth are both associated with type 2 diabetes in a random sample of middle-aged Danes
    K Pilgaard
    Steno Diabetes Center, Niels Steensens Vej 1, 2820 Gentofte, Denmark
    Diabetologia 53:2526-30. 2010
    ..We studied the associations of size at birth and prematurity with type 2 diabetes, insulin sensitivity and beta cell function in the Danish population-based Inter99 study (ClinicalTrials.gov NCT00289237)...
  12. ncbi Do the Joint British Society (JBS2) guidelines on prevention of cardiovascular disease with respect to plasma glucose improve risk stratification in the general population? Prospective cohort study
    E J Brunner
    Department of Epidemiology and Public Health, University College London, London, UK
    Diabet Med 27:550-5. 2010
    ....
  13. ncbi Changes in C-reactive protein levels before type 2 diabetes and cardiovascular death: the Whitehall II study
    A G Tabák
    Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6 BT, UK
    Eur J Endocrinol 163:89-95. 2010
    ..This study describes CRP trajectories prior to type 2 diabetes onset and fatal CVD...
  14. ncbi Low serum adiponectin predicts 10-year risk of type 2 diabetes and HbA1c independently of obesity, lipids, and inflammation: Whitehall II study
    A G Tabák
    Department of Epidemiology and Public Health, University College London, London WCE1 6BT, UK
    Horm Metab Res 41:626-9. 2009
    ..05). The observed robust, prospective associations support that adiponectin is an independent predictor of diabetes and the degree of glycaemic impairment...
  15. ncbi Risk factors for cardiac autonomic neuropathy in type 1 diabetes mellitus
    D R Witte
    Department of Epidemiology and Public Health, Royal Free and University College London Medical School, 1 19 Torrington Place, London, WC1E 6BT, UK
    Diabetologia 48:164-71. 2005
    ..Cardiac autonomic neuropathy (CAN) is associated with increased morbidity and mortality in type 1 diabetes. Apart from glycaemic control, risk factors for CAN have not been extensively studied...
  16. ncbi Study of agreement between LDL size as measured by nuclear magnetic resonance and gradient gel electrophoresis
    D R Witte
    EURODIAB, Department of Epidemiology and Public Health, Royal Free and University College London Medical School, London, United Kingdom
    J Lipid Res 45:1069-76. 2004
    ..In particular, the two methods should not be assumed to be interchangeable in women and diabetic subjects. Whether NMR or GGE predicts cardiovascular disease risk better has not yet been evaluated...