H H Parving

Summary

Affiliation: Steno Diabetes Center
Country: Denmark

Publications

  1. ncbi Differences between nisoldipine and lisinopril on glomerular filtration rates and albuminuria in hypertensive IDDM patients with diabetic nephropathy during the first year of treatment
    P Rossing
    Steno Diabetes Center, Gentofte, Denmark
    Diabetes 46:481-7. 1997
  2. ncbi Aldosterone synthase (CYP11B2)-344T/C polymorphism and renoprotective response to losartan treatment in diabetic nephropathy
    K J Schjoedt
    Steno Diabetes Center, Gentofte, Denmark
    Scand J Clin Lab Invest 66:173-80. 2006
  3. ncbi Prevalence and risk factors for microalbuminuria in a referred cohort of type II diabetic patients: a global perspective
    H H Parving
    Steno Diabetes Center, Copenhagen, Denmark
    Kidney Int 69:2057-63. 2006
  4. doi Optimal antiproteinuric dose of aliskiren in type 2 diabetes mellitus: a randomised crossover trial
    F Persson
    Steno Diabetes Center, Niels Steensenvej 1, DK 2820 Gentofte, Denmark
    Diabetologia 53:1576-80. 2010
  5. ncbi Plasma N-terminal pro-brain natriuretic peptide as a major risk marker for cardiovascular disease in patients with type 2 diabetes and microalbuminuria
    P Gaede
    Steno Diabetes Center, Niels Steensens Vej 2, 2820 Gentofte, Denmark
    Diabetologia 48:156-63. 2005
  6. doi Time course of the antiproteinuric and antihypertensive effects of direct renin inhibition in type 2 diabetes
    F Persson
    Steno Diabetes Center, Gentofte, Denmark
    Kidney Int 73:1419-25. 2008
  7. ncbi Renoprotective effects of angiotensin II receptor blockade in type 1 diabetic patients with diabetic nephropathy
    S Andersen
    Steno Diabetes Center, Copenhagen, Denmark
    Kidney Int 57:601-6. 2000
  8. doi Long-term prevention of diabetic nephropathy: an audit
    K J Schjoedt
    Steno Diabetes Center, Niels Steensens Vej 1, 2820 Gentofte, Denmark
    Diabetologia 51:956-61. 2008
  9. ncbi Aldosterone escape during blockade of the renin-angiotensin-aldosterone system in diabetic nephropathy is associated with enhanced decline in glomerular filtration rate
    K J Schjoedt
    Steno Diabetes Center, Niels Steensens Vej 2, 2820, Gentofte, Denmark
    Diabetologia 47:1936-9. 2004
  10. ncbi Increased sympathetic activity during sleep and nocturnal hypertension in Type 2 diabetic patients with diabetic nephropathy
    F S Nielsen
    Steno Diabetes Center, Gentofte, Denmark
    Diabet Med 16:555-62. 1999

Detail Information

Publications69

  1. ncbi Differences between nisoldipine and lisinopril on glomerular filtration rates and albuminuria in hypertensive IDDM patients with diabetic nephropathy during the first year of treatment
    P Rossing
    Steno Diabetes Center, Gentofte, Denmark
    Diabetes 46:481-7. 1997
    ..Longer follow-up is required to clarify whether these drugs have different renoprotective effects...
  2. ncbi Aldosterone synthase (CYP11B2)-344T/C polymorphism and renoprotective response to losartan treatment in diabetic nephropathy
    K J Schjoedt
    Steno Diabetes Center, Gentofte, Denmark
    Scand J Clin Lab Invest 66:173-80. 2006
    ....
  3. ncbi Prevalence and risk factors for microalbuminuria in a referred cohort of type II diabetic patients: a global perspective
    H H Parving
    Steno Diabetes Center, Copenhagen, Denmark
    Kidney Int 69:2057-63. 2006
    ..Early detection, monitoring of vascular complications, and more aggressive multifactorial treatment aiming at renal and vascular protection are urgently needed...
  4. doi Optimal antiproteinuric dose of aliskiren in type 2 diabetes mellitus: a randomised crossover trial
    F Persson
    Steno Diabetes Center, Niels Steensenvej 1, DK 2820 Gentofte, Denmark
    Diabetologia 53:1576-80. 2010
    ..The optimal antiproteinuric dose of aliskiren is unknown. This study compared the effect of placebo and increasing doses of aliskiren on urinary albumin excretion rate (UAER)...
  5. ncbi Plasma N-terminal pro-brain natriuretic peptide as a major risk marker for cardiovascular disease in patients with type 2 diabetes and microalbuminuria
    P Gaede
    Steno Diabetes Center, Niels Steensens Vej 2, 2820 Gentofte, Denmark
    Diabetologia 48:156-63. 2005
    ..We examined whether plasma N-terminal probrain natriuretic peptide (NT-proBNP) predicts cardiovascular outcome in patients with type 2 diabetes...
  6. doi Time course of the antiproteinuric and antihypertensive effects of direct renin inhibition in type 2 diabetes
    F Persson
    Steno Diabetes Center, Gentofte, Denmark
    Kidney Int 73:1419-25. 2008
    ..Our study shows that aliskiren reduced 24 h SBP, and this was associated with a reduction in albuminuria in type 2 diabetic patients...
  7. ncbi Renoprotective effects of angiotensin II receptor blockade in type 1 diabetic patients with diabetic nephropathy
    S Andersen
    Steno Diabetes Center, Copenhagen, Denmark
    Kidney Int 57:601-6. 2000
    ..Therefore, we compared the renal and hemodynamic effects of specific intervention in the renin-angiotensin system by blockade of the angiotensin II subtype-1 receptor to the effect of ACE inhibition...
  8. doi Long-term prevention of diabetic nephropathy: an audit
    K J Schjoedt
    Steno Diabetes Center, Niels Steensens Vej 1, 2820 Gentofte, Denmark
    Diabetologia 51:956-61. 2008
    ....
  9. ncbi Aldosterone escape during blockade of the renin-angiotensin-aldosterone system in diabetic nephropathy is associated with enhanced decline in glomerular filtration rate
    K J Schjoedt
    Steno Diabetes Center, Niels Steensens Vej 2, 2820, Gentofte, Denmark
    Diabetologia 47:1936-9. 2004
    ..We evaluated the influence of plasma aldosterone levels on progression of diabetic nephropathy during long-term blockade of the renin-angiotensin-aldosterone system...
  10. ncbi Increased sympathetic activity during sleep and nocturnal hypertension in Type 2 diabetic patients with diabetic nephropathy
    F S Nielsen
    Steno Diabetes Center, Gentofte, Denmark
    Diabet Med 16:555-62. 1999
    ..To elucidate the putative factors involved in the blunted nocturnal blood pressure reduction in hypertensive Type 2 diabetic patients with diabetic nephropathy...
  11. ncbi Remission and regression in the nephropathy of type 1 diabetes when blood pressure is controlled aggressively
    P Hovind
    Steno Diabetes Center, Gentofte, Denmark
    Kidney Int 60:277-83. 2001
    ..To examine whether remission and regression of diabetic nephropathy are possible in type 1 diabetic patients, we analyzed data from a prospective observational cohort study that was started in 1983...
  12. ncbi Prolonged QTc interval predicts mortality in patients with Type 1 diabetes mellitus
    P Rossing
    Steno Diabetes Center, Gentofte, Denmark
    Diabet Med 18:199-205. 2001
    ..To evaluate prolonged QTc interval and QT dispersion as predictors of all-cause and cardiovascular mortality after adjustment for well-established risk factors in Type 1 diabetic patients...
  13. ncbi Long-term renoprotective effect of nisoldipine and lisinopril in type 1 diabetic patients with diabetic nephropathy
    L Tarnow
    Steno Diabetes Center, Gentofte, Denmark
    Diabetes Care 23:1725-30. 2000
    ..To compare the long-term effect on kidney function of a long-acting calcium antagonist (nisoldipine) versus a long-acting ACE inhibitor (lisinopril) in hypertensive type 1 diabetic patients with diabetic nephropathy...
  14. ncbi Fish oil in diabetic nephropathy
    P Rossing
    Steno Diabetes Center, Gentofte, Denmark
    Diabetes Care 19:1214-9. 1996
    ..Therefore, we evaluated the long-term effect of fish oil in diabetic nephropathy...
  15. ncbi Plasma N-terminal pro-brain natriuretic peptide as an independent predictor of mortality in diabetic nephropathy
    L Tarnow
    Steno Diabetes Center, Niels Steensens Vej 2, 2820 Gentofte, Denmark
    Diabetologia 48:149-55. 2005
    ..This study investigated the prognostic value of NT-proBNP in a large cohort of type 1 diabetic patients with and without diabetic nephropathy...
  16. ncbi Cardiovascular morbidity and early mortality cluster in parents of type 1 diabetic patients with diabetic nephropathy
    L Tarnow
    Steno Diabetes Center, Gentofte, Denmark
    Diabetes Care 23:30-3. 2000
    ..The aim of the present study was to evaluate these hypotheses in parents of a large group of type 1 diabetic patients with and without diabetic nephropathy...
  17. ncbi Preventing diabetic nephropathy: an audit
    H P Hansen
    Steno Diabetes Center, Gentofte, Denmark
    Scand J Clin Lab Invest 61:471-7. 2001
    ....
  18. ncbi Impaired autoregulation of GFR in hypertensive non-insulin dependent diabetic patients
    P K Christensen
    Steno Diabetes Center, Gentofte, Denmark
    Kidney Int 52:1369-74. 1997
    ..5 (divided by 2.7 to 13.7) ml/min/1.73 m2 (P = 0.18). Our study suggests that hypertensive NIDDM patients, particularly patients with nephropathy, frequently suffer from impaired or abolished autoregulation of GFR...
  19. ncbi Pregnancy and progression of diabetic nephropathy
    K Rossing
    Steno Diabetes Center, Niels Steensens Vej 2, DK 2820 Gentofte, Denmark
    Diabetologia 45:36-41. 2002
    ..Pregnancy could damage kidney function in diabetic nephropathy. We investigated the long-term impact of pregnancy on the progression of diabetic nephropathy...
  20. ncbi Aldosterone synthase (CYP11B2) -344T/C polymorphism is not associated with the initiation and progression of diabetic nephropathy in Caucasian Type 1 diabetic patients
    M Lajer
    Steno Diabetes Center, Gentofte, Denmark
    Diabet Med 23:675-80. 2006
    ..Therefore, we investigated whether the -344T/C polymorphism is associated with the development and progression of diabetic nephropathy in Type 1 diabetes mellitus...
  21. ncbi Beneficial impact of spironolactone on nephrotic range albuminuria in diabetic nephropathy
    K J Schjoedt
    Steno Diabetes Center, Gentofte, Denmark
    Kidney Int 70:536-42. 2006
    ....
  22. ncbi Plasma N-terminal pro-B-type natriuretic peptide and mortality in type 2 diabetes
    L Tarnow
    Steno Diabetes Center, Niels Steensens Vej 2, DK 2820, Gentofte, Denmark
    Diabetologia 49:2256-62. 2006
    ..Elevated NT-proBNP predicts excess morbidity and mortality in diabetic patients with an elevated urinary albumin excretion rate. This study investigated the prognostic value of NT-proBNP in a cohort of type 2 diabetic patients...
  23. ncbi Targeting hyperglycaemia with either metformin or repaglinide in non-obese patients with type 2 diabetes: results from a randomized crossover trial
    S S Lund
    Steno Diabetes Center, Gentofte, Denmark
    Diabetes Obes Metab 9:394-407. 2007
    ..In this investigator-initiated trial, we evaluated the effect of metformin vs. an insulin secretagogue, repaglinide on glycaemic regulation and markers of inflammation and insulin sensitivity in non-obese patients with T2DM...
  24. doi Evaluation of placental growth factor and soluble Fms-like tyrosine kinase 1 as predictors of all-cause and cardiovascular mortality in patients with Type 1 diabetes with and without diabetic nephropathy
    S Theilade
    Steno Diabetes Center, Gentofte, Denmark
    Diabet Med 29:337-44. 2012
    ..The aim of this study is to evaluate the predictive value of placental growth factor and soluble Fms-like tyrosine kinase 1 in relation to all-cause and cardiovascular mortality and decline in kidney function in Type 1 diabetes...
  25. doi Telomere length predicts all-cause mortality in patients with type 1 diabetes
    A S Astrup
    Steno Diabetes Center, Att Ingelise Holstein, 2820 Gentofte, Denmark
    Diabetologia 53:45-8. 2010
    ..We aimed to evaluate differences in telomere length in patients with type 1 diabetes with or without diabetic nephropathy; we also evaluated the prognostic value of telomere length...
  26. doi Effect of adjunct metformin treatment on levels of plasma lipids in patients with type 1 diabetes
    S S Lund
    Steno Diabetes Center, Niels Steensens Vej 2, 2820 Gentofte, Denmark
    Diabetes Obes Metab 11:966-77. 2009
    ..In this study, we report the effect of a 1-year treatment with metformin vs. placebo on plasma lipids in T1DM patients and persistent poor glycaemic control...
  27. ncbi Remission of nephrotic-range albuminuria in type 1 diabetic patients
    P Hovind
    Steno Diabetes Center, Gentofte, Denmark
    Diabetes Care 24:1972-7. 2001
    ..To evaluate the cumulative incidence of nephrotic-range albuminuria (NRA), the frequency of remission, and the impact on progression, we analyzed data from a prospective cohort study of type 1 diabetic patients with diabetic nephropathy...
  28. ncbi Progression of diabetic nephropathy
    P Hovind
    Steno Diabetes Center, Gentofte, Denmark
    Kidney Int 59:702-9. 2001
    ..The risk factors of losing filtration power (progression promoters) have not been clearly identified. Furthermore, information on optimal arterial blood pressure, glycemic control, and cholesterol levels are lacking...
  29. ncbi Lack of effect of fish oil supplementation on coagulation and transcapillary escape rate of albumin in insulin-dependent diabetic patients with diabetic nephropathy
    B Myrup
    Steno Diabetes Center, Gentofte, Denmark
    Scand J Clin Lab Invest 61:349-56. 2001
    ..CONCLUSION: Increased transcapillary escape rate of albumin and activity could not be modified during diet supplementation with fish oil in insulin-dependent diabetic patients with nephropathy...
  30. doi Spironolactone diminishes urinary albumin excretion in patients with type 1 diabetes and microalbuminuria: a randomized placebo-controlled crossover study
    S E Nielsen
    Steno Diabetes Center, Niels Steensens Vej, Gentofte, Denmark
    Diabet Med 29:e184-90. 2012
    ..We expected an impact of spironolactone in early diabetic nephropathy, and for this hypothesis we studied the effect on markers of glomerular and tubular damage in patients with Type 1 diabetes and persistent microalbuminuria...
  31. ncbi Plasma concentrations of VCAM-1 and ICAM-1 are elevated in patients with Type 1 diabetes mellitus with microalbuminuria and overt nephropathy
    P Clausen
    Department of Nephrology and Endocrinology, State University Hospital, Copenhagen, Denmark
    Diabet Med 17:644-9. 2000
    ....
  32. ncbi Progression of diabetic nephropathy: role of plasma homocysteine and plasminogen activator inhibitor-1
    P Hovind
    Steno Diabetes Center, Gentofte, Denmark
    Am J Kidney Dis 38:1376-80. 2001
    ..After adjustment for other well-established risk factors for progression of nephropathy in a multiple linear regression analysis, however, neither tHcy levels nor PAI-1 levels were independent predictors of rate of decline in GFR...
  33. ncbi Effect of short-term hyperglycaemia on haemodynamics in type 1 diabetic patients
    P Jacobsen
    Steno Diabetes Center, Gentofte, Denmark
    J Intern Med 254:464-71. 2003
    ..We tested the impact of short-term hyperglycaemia on systemic blood pressure and regulatory hormones in type 1 diabetic patients...
  34. ncbi Remission of nephrotic-range albuminuria reduces risk of end-stage renal disease and improves survival in type 2 diabetic patients
    K Rossing
    Steno Diabetes Center, Gentofte, Denmark
    Diabetologia 48:2241-7. 2005
    ..We evaluated the impact of remission of nephrotic-range albuminuria (>2500 mg/24 h) (NRA) on end-stage renal disease (ESRD) and mortality in type 2 diabetic patients with nephropathy...
  35. doi Arterial stiffness and endothelial dysfunction independently and synergistically predict cardiovascular and renal outcome in patients with type 1 diabetes
    S Theilade
    Steno Diabetes Center, Gentofte, Denmark
    Diabet Med 29:990-4. 2012
    ....
  36. doi Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Kidney Injury Molecule 1 (KIM1) in patients with diabetic nephropathy: a cross-sectional study and the effects of lisinopril
    S E Nielsen
    Steno Diabetes Center, Gentofte Hospital, Denmark
    Diabet Med 27:1144-50. 2010
    ..In addition, the effect of renoprotective treatment on urinary NGAL was evaluated in diabetic nephropathy...
  37. doi Optimal dose of lisinopril for renoprotection in type 1 diabetic patients with diabetic nephropathy: a randomised crossover trial
    K J Schjoedt
    Steno Diabetes Center, Gentofte, Denmark
    Diabetologia 52:46-9. 2009
    ....
  38. ncbi Double-blind, randomised study of the effect of combined treatment with vitamin C and E on albuminuria in Type 2 diabetic patients
    P Gaede
    Steno Diabetes Center, Niels Steensens Vej 2, 2820 Gentofte, Denmark
    Diabet Med 18:756-60. 2001
    ..We tested the hypothesis that supplementation of both vitamin C and E in pharmacological doses lowers AER in Type 2 diabetic patients with persistent micro/macroalbuminuria...
  39. doi The PPAR gamma 2 Pro12Ala variant predicts ESRD and mortality in patients with type 1 diabetes and diabetic nephropathy
    A Jorsal
    Steno Diabetes Center, Niels Steensens Vej 2, 2820 Gentofte, Denmark
    Mol Genet Metab 94:347-51. 2008
    ..040). In conclusion, the Pro12Ala polymorphism is not associated with type 1 diabetic nephropathy. The Ala-allele is associated with enhanced decline in GFR and predicts ESRD and all-cause mortality in patients with nephropathy...
  40. ncbi Left ventricular hypertrophy in normoalbuminuric type 2 diabetic patients not taking antihypertensive treatment
    A Sato
    Steno Diabetes Center, Gentofte, Denmark
    QJM 98:879-84. 2005
    ..Left ventricular hypertrophy (LVH) is an independent risk factor for myocardial ischaemia, cardiac arrhythmia, sudden death, and heart failure, all common findings in patients with type 2 diabetes...
  41. ncbi Poor prognosis in proteinuric type 2 diabetic patients with retinopathy: insights from the RENAAL study
    H H Parving
    Steno Diabetes Center, Niels Steensensvej 2, DK 2820 Gentofte, Denmark
    QJM 98:119-26. 2005
    ..Retinopathy is the clinical hallmark of generalized microangiopathy in diabetes...
  42. ncbi Birth weight--a risk factor for progression in diabetic nephropathy?
    P Jacobsen
    Steno Diabetes Center, Gentofte, Denmark
    J Intern Med 253:343-50. 2003
    ..Oligonephropathy has been linked to hypertension and renal disease in adult life. We tested the concept that low weight at birth acts as a risk factor for progression of diabetic nephropathy...
  43. ncbi Autoregulated glomerular filtration rate during candesartan treatment in hypertensive type 2 diabetic patients
    P K Christensen
    Steno Diabetes Center, Gentofte, Denmark
    Kidney Int 60:1435-42. 2001
    ..1 (-5.5 to 5.8) mL/min/1.73 m2 (NS). CONCLUSION: Candesartan reduces blood pressure without adversely altering the preserved ability to autoregulate GFR in hypertensive type 2 diabetic patients without nephropathy...
  44. ncbi Long-term beneficial effect of ACE inhibition on diabetic nephropathy in normotensive type 1 diabetic patients
    H H Parving
    Steno Diabetes Center, Copenhagen, Denmark
    Kidney Int 60:228-34. 2001
    ..The purpose of this study was to assess whether long-term (8 years) inhibition of angiotensin-converting enzyme (ACE) protects kidney function in normotensive type 1 diabetic patients with diabetic nephropathy...
  45. doi Urinary sulphate excretion and progression of diabetic nephropathy in Type 1 diabetes
    G Andrésdóttir
    Steno Diabetes Center, Gentofte, Denmark
    Diabet Med 30:563-6. 2013
    ..We aimed to determine whether urinary sulphate excretion, as a proxy for hydrogen sulphide, was associated with progression of diabetic nephropathy...
  46. ncbi Hypertension and diabetes: the scope of the problem
    H H Parving
    Steno Diabetes Center, Gentofte, Denmark
    Blood Press Suppl 2:25-31. 2001
    ..The trials were completed at the end of 2000...
  47. ncbi Pregnancy-associated plasma protein A in a large cohort of Type 1 diabetic patients with and without diabetic nephropathy-a prospective follow--up study
    A S Astrup
    Steno Diabetes Center, Gentofte, Denmark
    Diabet Med 24:1381-5. 2007
    ..Diabetic nephropathy is characterized by increased cardiovascular risk. We investigated the prognostic value of PAPP-A in a large cohort of Type 1 diabetic patients...
  48. doi Plasma osteoprotegerin levels predict cardiovascular and all-cause mortality and deterioration of kidney function in type 1 diabetic patients with nephropathy
    A Jorsal
    Steno Diabetes Center, Niels Steensens Vej 2, 2820, Gentofte, Denmark
    Diabetologia 51:2100-7. 2008
    ..The aim of this study was to investigate the predictive value of plasma levels of osteoprotegerin in relation to mortality, cardiovascular events and deterioration in kidney function in patients with type 1 diabetes...
  49. doi Aliskiren combined with losartan in type 2 diabetes and nephropathy
    Hans Henrik Parving
    Department of Medical Endocrinology, Rigshospitalet, Copenhagen, Denmark
    N Engl J Med 358:2433-46. 2008
    ....
  50. ncbi Evolving strategies for renoprotection: diabetic nephropathy
    H H Parving
    Steno Diabetes Center, Copenhagen, Denmark
    Curr Opin Nephrol Hypertens 10:515-22. 2001
    ..Many potential treatment modalities in preventing and treating diabetic nephropathy are presently being evaluated...
  51. ncbi Time to consider ACE insertion/deletion genotypes and individual renoprotective treatment in diabetic nephropathy?
    P K Jacobsen
    Steno Diabetes Center, Gentofte, Denmark
    Kidney Int 69:1293-5. 2006
    ..This Commentary summarizes the impact of the angiotensin-converting enzyme (ACE) insertion/deletion polymorphism in the ACE gene on initiation and progression of diabetic nephropathy...
  52. ncbi Renal function and structure in albuminuric type 2 diabetic patients without retinopathy
    P K Christensen
    Steno Diabetes Center, Gentofte, Denmark
    Nephrol Dial Transplant 16:2337-47. 2001
    ..Therefore, a long-term study evaluating the structural-functional relationship in albuminuric type 2 diabetic patients without retinopathy was performed...
  53. ncbi Dual blockade of the renin-angiotensin-aldosterone system in diabetic nephropathy: the role of aldosterone
    K J Schjoedt
    Steno Diabetes Center, Niels Steensens Vej 2, 2820 Gentofte, Denmark
    Horm Metab Res 37:4-8. 2005
    ..The beneficial response may be influenced by genetic factors and reductions in blood pressure and plasma aldosterone concentrations...
  54. ncbi Controlling hypertension in diabetes
    H H Parving
    Steno Diabetes Center, Gentofte, Denmark
    Acta Diabetol 39:S35-40. 2002
    ..Consequently, the combination of ACE inhibitors with other first-line drugs, such as CCBs, diuretics and beta-blockers, is recommended for the therapeutic management of hypertensive diabetic patients...
  55. ncbi The association between metabolic syndrome, microalbuminuria and impaired renal function in the general population: impact on cardiovascular disease and mortality
    K P Klausen
    Copenhagen City Heart Study, Epidemiological Research Unit, Bispebjerg University Hospital, Copenhagen, Denmark
    J Intern Med 262:470-8. 2007
    ..We also aimed to determine the risk of death and CVD at different levels of microalbuminuria and renal function and numbers of components in the metabolic syndrome...
  56. doi Insulin analogues and severe hypoglycaemia in type 1 diabetes
    P L Kristensen
    Steno Diabetes Center, Niels Steensens Vej 2, Gentofte, Denmark
    Diabetes Res Clin Pract 96:17-23. 2012
    ..We studied the frequency of severe hypoglycaemia in unselected patients with type 1 diabetes treated with insulin analogues, human insulin, or mixed regimens...
  57. ncbi Elevated levels of plasma von Willebrand factor and the risk of macro- and microvascular disease in type 2 diabetic patients with microalbuminuria
    P Gaede
    Steno Diabetes Center, Gentofte, Denmark
    Nephrol Dial Transplant 16:2028-33. 2001
    ....
  58. doi Multifactorial treatment increases endothelial progenitor cells in patients with type 2 diabetes
    H Reinhard
    Steno Diabetes Center, Niels Steensenvej 1, DK 2820 Gentofte, Denmark
    Diabetologia 53:2129-33. 2010
    ..Our aim, therefore, was to evaluate in type 2 diabetic patients whether the numbers of EPC derived from peripheral blood mononuclear cells is influenced by a multifactorial treatment strategy...
  59. ncbi Diabetic microvascular complications are not associated with two polymorphisms in the GLUT-1 and PC-1 genes regulating glucose metabolism in Caucasian type 1 diabetic patients
    L Tarnow
    Steno Diabetes Center, Gentofte, Denmark
    Nephrol Dial Transplant 16:1653-6. 2001
    ....
  60. ncbi The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes
    H H Parving
    Steno Diabetes Center, Copenhagen, Denmark
    N Engl J Med 345:870-8. 2001
    ..02). CONCLUSIONS: Irbesartan is renoprotective independently of its blood-pressure-lowering effect in patients with type 2 diabetes and microalbuminuria...
  61. doi Sustained postprandial decrease in plasma levels of LDL cholesterol in patients with type-2 diabetes mellitus
    S S Lund
    Steno Diabetes Center, Gentofte, Denmark
    Scand J Clin Lab Invest 68:628-40. 2008
    ..Postprandial lipid metabolism has been linked to CVD, but little is known about the postprandial LDL-C profile in patients with type-2 diabetes (T2DM). We aimed to study the postprandial levels of LDL-C in T2DM patients...
  62. ncbi Association of aldose reductase gene Z+2 polymorphism with reduced susceptibility to diabetic nephropathy in Caucasian Type 1 diabetic patients
    M Lajer
    Steno Diabetes Centre, Gentofte, Denmark
    Diabet Med 21:867-73. 2004
    ..However data are conflicting. Therefore, we investigated whether this polymorphism is associated with diabetic nephropathy and retinopathy in Type 1 diabetes mellitus in a large case-control study and a family-based analysis...
  63. ncbi Adverse effects of left ventricular hypertrophy in the reduction of endpoints in NIDDM with the angiotensin II antagonist losartan (RENAAL) study
    G Boner
    Department of Internal Medicine, Sackler Faculty of Medicine, University of Tel Aviv, Ramat Aviv, Tel Aviv, Israel
    Diabetologia 48:1980-7. 2005
    ....
  64. ncbi The prevalence of coeliac disease in adult Danish patients with type 1 diabetes with and without nephropathy
    H Skovbjerg
    Diabetologia 48:1416-7. 2005
  65. ncbi CYP2C9 variant modifies blood pressure-lowering response to losartan in Type 1 diabetic patients with nephropathy
    M Lajer
    Diabet Med 24:323-5. 2007
  66. ncbi Endothelial dysfunction and low-grade inflammation and the progression of retinopathy in Type 2 diabetes
    A M W Spijkerman
    Institute for Research in Extramural Medicine, VU University Medical Center, Amsterdam, The Netherlands
    Diabet Med 24:969-76. 2007
    ..To study whether microalbuminuria, endothelial dysfunction and low-grade inflammation are associated with the presence and progression of diabetic retinopathy...
  67. ncbi Total plasma homocysteine is associated with hypertension in Type I diabetic patients
    S Neugebauer
    Third Department of Internal Medicine, Fukushima Medical University, Hikarigaoka 1, 960 1295 Fukushima, Japan
    Diabetologia 45:1315-24. 2002
    ..This study explores the relation between plasma homocysteine concentrations, methylenetetrahydrofolate reductase gene polymorphism, hypertension, diabetic microvascular and macrovascular complications associated with kidney function...
  68. ncbi Increased serum adiponectin levels in type 1 diabetic patients with microvascular complications
    J Frystyk
    Medical Research Laboratories, Clinical Institute and Medical Department M Diabetes and Endocrinology, Aarhus University Hospital, Aarhus C, Denmark
    Diabetologia 48:1911-8. 2005
    ..In type 1 diabetic patients, the relationship between ADPN and the presence of vascular complications is largely unknown...
  69. doi Increased renal gene transcription of protein kinase C-beta in human diabetic nephropathy: relationship to long-term glycaemic control
    R G Langham
    University of Melbourne Department of Medicine, St Vincent s Hospital, Fitzroy, Vic, Australia
    Diabetologia 51:668-74. 2008
    ..We sought to determine whether in addition to activation, diabetes may lead to increased transcription of two PKC isoforms that have been implicated in the pathogenesis of diabetic nephropathy, PKC-alpha and PKC-beta...