Research Topics
Species | E NilssonSummaryAffiliation: Steno Diabetes Center Country: Denmark Publications
| Collaborators
|
Detail Information
Publications
Impact of 9 days of bed rest on hepatic and peripheral insulin action, insulin secretion, and whole-body lipolysis in healthy young male offspring of patients with type 2 diabetesAmra C Alibegovic
Steno Diabetes Centre, Gentofte, Denmark
Diabetes 58:2749-56. 2009..The aim of this study was to investigate the impact of 9 days of bed rest on insulin secretion, insulin action, and whole-body glucose and fat metabolism in first-degree relative (FDR) and matched control (CON) subjects...
Increased rate of whole body lipolysis before and after 9 days of bed rest in healthy young men born with low birth weightA C Alibegovic
Steno Diabetes Centre, Gentofte, Denmark
Am J Physiol Endocrinol Metab 298:E555-64. 2010..Nine days of bed rest causes severe peripheral insulin resistance and reduced WBL and skeletal muscle HSL activity, as well as a compensatory increased insulin secretion, with no differences in LBW subjects and controls...
The T-allele of TCF7L2 rs7903146 associates with a reduced compensation of insulin secretion for insulin resistance induced by 9 days of bed restAmra C Alibegovic
Steno Diabetes Centre, Gentofte, Denmark
Diabetes 59:836-43. 2010..The aim of this study was to determine whether the type 2 diabetes-associated T-allele of transcription factor 7-like 2 (TCF7L2) rs7903146 associates with impaired insulin secretion to compensate for insulin resistance induced by bed rest...
Insulin resistance induced by physical inactivity is associated with multiple transcriptional changes in skeletal muscle in young menA C Alibegovic
Steno Diabetes Center, Gentofte, Denmark
Am J Physiol Endocrinol Metab 299:E752-63. 2010..Lack of complete normalization of changes after 4 wk of retraining underscores the importance of maintaining a minimum of daily physical activity...
Differential aetiology and impact of phosphoinositide 3-kinase (PI3K) and Akt signalling in skeletal muscle on in vivo insulin actionM Friedrichsen
Steno Diabetes Center, Niels Steensens Vej 1, Gentofte, Denmark
Diabetologia 53:1998-2007. 2010..We therefore aimed to investigate the regulation of proximal insulin signalling in skeletal muscle and its effect on glucose metabolism in a large non-diabetic population...
Effects of short-term high-fat overfeeding on genome-wide DNA methylation in the skeletal muscle of healthy young menS C Jacobsen
Steno Diabetes Center, Gentofte, Denmark
Diabetologia 55:3341-9. 2012..We examined the effect of a short-term high-fat overfeeding (HFO) diet on genome-wide DNA methylation patterns in human skeletal muscle...
