Research Topics
| A S WiikSummaryAffiliation: Statens Serum Institut Country: Denmark Publications
| Collaborators
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Detail Information
Publications
Laboratory diagnostics in vasculitis patientsA Wiik
Department of Autoimmunology, Statens Serum Institut, Copenhagen, Denmark
Isr Med Assoc J 3:275-7. 2001..ANCA-related SVV and drug-induced vasculitis or lupus syndromes have characteristic ANCA profiles that can help distinguish these conditions from other inflammatory diseases...
Environmental risk factors differ between rheumatoid arthritis with and without auto-antibodies against cyclic citrullinated peptidesMerete Pedersen
Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, Artillerivej 5, DK 2300 Copenhagen S, Denmark
Arthritis Res Ther 8:R133. 2006..Major differences in risk factor profiles suggest distinct etiologies for anti-CCP-positive and anti-CCP-negative RA...
[Diagnostic strategies for autoimmune rheumatic diseases]A S Wiik
Department of Autoimmunology, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Danemark
Z Rheumatol 66:219-20, 222-4. 2007..Late or wrong decisions during follow-up lead to unnecessary suffering and far higher lifetime costs for chronic diseases such as those found in rheumatology...
European attempts to set guidelines for improving diagnostics of autoimmune rheumatic disordersA Wiik
Department of Autoimmunology, Statens Serum Institut, Copenhagen, Denmark
Lupus 15:391-6. 2006..European efforts to secure rational diagnostic work-up in autoimmune rheumatic disease have led to a better dialogue between clinicians and laboratory scientists in several countries...
Clinical and laboratory characteristics of drug-induced vasculitic syndromesAllan Wiik
Department of Autoimmunology, Statens Serum Institut, Copenhagen, Denmark
Arthritis Res Ther 7:191-2. 2005..Clinically, skin vasculitis and arthralgias predominated and renal vasculitis was rare...
Anti-nuclear autoantibodies: clinical utility for diagnosis, prognosis, monitoring, and planning of treatment strategy in systemic immunoinflammatory diseasesA S Wiik
Department of Autoimmunology, Statens Serum Institut, Copenhagen S, Denmark
Scand J Rheumatol 34:260-8. 2005..Borders between positive and negative values should aim at attaining a high diagnostic specificity towards clinically important disease controls...
Systemic small vessel vasculitis: pathophysiological aspects of antineutrophil cytoplasm antibodies (ANCA). A review on recent findingsA Wiik
Department of Autoimmunology, Statens Serum Institut, Artillerivej 5, DK-2300 Copenhagen S, Denmark
Autoimmun Rev 3:S51-3. 2004
Cutting edge diagnostics in rheumatology: the role of patients, clinicians, and laboratory scientists in optimizing the use of autoimmune serologyAllan S Wiik
Statens Serum Institut, Copenhagen, Denmark
Arthritis Rheum 51:291-8. 2004
Appropriateness of autoantibody testing in clinical medicineAllan S Wiik
Department of Autoimmunology, Statens Serum Institut, Bldg 81, 5th Floor, Room 544, Artillerivej 5, DK 2300 Copenhagen S, Denmark
Clin Chim Acta 333:177-80. 2003..Pathologically expressed autoantibodies reflect ongoing immune-mediated inflammation in patients and may even be regarded as surrogate markers of disease prognosis and clinical outcome in certain clinical settings...
Neutrophil-specific autoantibodies in chronic inflammatory bowel diseasesAllan Wiik
Department of Autoimmunology, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark
Autoimmun Rev 1:67-72. 2002..Laboratory reports on NSA-positivity must be clearly distinguishable from reports on ANCA to help avoid clinical misinterpretation...
Autoantibodies in vasculitisAllan Wiik
Department of Autoimmunology, Statens Serum Institut, Copenhagen, Denmark
Arthritis Res Ther 5:147-52. 2003..Although autoantibodies to endothelial cells may be important players in the pathogenesis of several vasculitic conditions, they have not gained clinical popularity because of lack of standardized detection methods...
[Laboratory diagnostics in rheumatology]Allan Wiik
Autoimmunafdelingen, Statens Serum Institut, bygning 81, rum 544, Artillerivej 5, DK 2300 København S
Ugeskr Laeger 164:610-4. 2002..A clinically important use of serodiagnostics can only be implemented by a close collaboration between clinicians and laboratory specialists. A tentative diagnosis is the best basis for ordering and interpreting laboratory results...
Clinical use of serological tests for antineutrophil cytoplasmic antibodies. What do the studies say?A S Wiik
Department of Autoimmunology, Statens Serum Institut, Copenhagen, Denmark
Rheum Dis Clin North Am 27:799-813, vi-vii. 2001..Local serum banks containing samples from patients with well-characterized chronic immunoinflammatory diseases and ANCA-associated vasculitides are needed for such important studies whether in-house or commercial assays are used...
Distinct differences in autoantigen specificity of anti-neutrophil cytoplasm antibodies in systemic vasculitides and other inflammatory diseasesA Wiik
Department of Autoimmunology, Statens Serum Institut, Copenhagen, Denmark
Isr Med Assoc J 1:4-7. 1999..Anti-neutrophil cytoplasm antibodies in necrotizing vasculitides need to be distinguished from ANCAs in other inflammatory conditions to avoid clinical misinterpretation...
The immune response to citrullinated proteins in patients with rheumatoid arthritis: genetic, clinical, technical, and epidemiological aspectsAllan S Wiik
Department of Autoimmunology, Statens Serum Institut, Copenhagen S, Denmark
Clin Rev Allergy Immunol 32:13-22. 2007..The antibody can sometimes be found several years before the onset of clinical symptoms of RA, which may represent an open window for preventive measures to be taken...
