Christine Stabell Benn

Summary

Affiliation: Statens Serum Institut
Country: Denmark

Publications

  1. ncbi request reprint No strong long-term effect of vitamin A supplementation in infancy on CD4 and CD8 T-cell subsets. A community study from Guinea-Bissau, West Africa
    C S Benn
    Department of Epidemiology Research, Statens Serum Institut, 5 Artillerivej, 2300 Copenhagen S, Denmark
    Ann Trop Paediatr 20:259-64. 2000
  2. doi request reprint A small jab - a big effect: nonspecific immunomodulation by vaccines
    Christine S Benn
    Research Center for Vitamins and Vaccines CVIVA, Statens Serum Institut, Institute of Clinical Research, University of Southern Denmark, and Odense University Hospital, Denmark Electronic address
    Trends Immunol 34:431-9. 2013
  3. doi request reprint Diphtheria-tetanus-pertussis vaccination administered after measles vaccine: increased female mortality?
    Christine Stabell Benn
    Bandim Health Project, Research Center for Vitamins and Vaccines, Statens Serum Institut, Copenhagen S, Denmark
    Pediatr Infect Dis J 31:1095-7. 2012
  4. pmc The impact of different doses of vitamin A supplementation on male and female mortality. A randomised trial from Guinea-Bissau
    Dorthe Yakymenko
    Bandim Health Project, INDEPTH Network, Apartado 861, Bissau, Guinea Bissau
    BMC Pediatr 11:77. 2011
  5. pmc Randomised study of effect of different doses of vitamin A on childhood morbidity and mortality
    Christine Stabell Benn
    Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen, Denmark
    BMJ 331:1428-32. 2005
  6. doi request reprint Does vitamin A supplementation interact with routine vaccinations? An analysis of the Ghana Vitamin A Supplementation Trial
    Christine S Benn
    Statens Serum Institut, Copenhagen, Denmark
    Am J Clin Nutr 90:629-39. 2009
  7. ncbi request reprint [High-dose vitamin A supplementation decreases childhood mortality rates in low-income countries--can the results be improved?]
    Christine Stabell Benn
    Guinea Bissau Statens Serum Institut, Bandim Health Project, og Københavns Universitet
    Ugeskr Laeger 168:2442-5. 2006
  8. doi request reprint The effect of high-dose vitamin A supplementation administered with BCG vaccine at birth may be modified by subsequent DTP vaccination
    Christine Stabell Benn
    Bandim Health Project, Statens Serum Institut, Copenhagen, Denmark
    Vaccine 27:2891-8. 2009
  9. ncbi request reprint [Gender differences in response to preventive health care interventions. Do we have to treat girls and boys differently to treat them equally?]
    Christine Stabell Benn
    Bandim Health Project, Statens Serum Institut, København
    Ugeskr Laeger 168:3045-6. 2006
  10. doi request reprint Should infant girls receive micronutrient supplements?
    Christine Stabell Benn
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    Int J Epidemiol 38:586-90. 2009

Collaborators

Detail Information

Publications63

  1. ncbi request reprint No strong long-term effect of vitamin A supplementation in infancy on CD4 and CD8 T-cell subsets. A community study from Guinea-Bissau, West Africa
    C S Benn
    Department of Epidemiology Research, Statens Serum Institut, 5 Artillerivej, 2300 Copenhagen S, Denmark
    Ann Trop Paediatr 20:259-64. 2000
    ..Based on these observations, vitamin A supplementation does not seem to have a strong long-term effect on CD4 and CD8 T-cell subsets in infants without clinical vitamin A deficiency...
  2. doi request reprint A small jab - a big effect: nonspecific immunomodulation by vaccines
    Christine S Benn
    Research Center for Vitamins and Vaccines CVIVA, Statens Serum Institut, Institute of Clinical Research, University of Southern Denmark, and Odense University Hospital, Denmark Electronic address
    Trends Immunol 34:431-9. 2013
    ..Hence, epidemiological findings are backed by immunological data. This generates a new understanding of the immune system and about how it can be modulated by vaccines to impact the general resistance to disease. ..
  3. doi request reprint Diphtheria-tetanus-pertussis vaccination administered after measles vaccine: increased female mortality?
    Christine Stabell Benn
    Bandim Health Project, Research Center for Vitamins and Vaccines, Statens Serum Institut, Copenhagen S, Denmark
    Pediatr Infect Dis J 31:1095-7. 2012
    ..23-10.26) times higher risk of dying before 36 months of age, whereas it made no difference in male children (0.97 [0.34-2.80]). The result supports that receiving DTP after measles vaccine affects female children negatively...
  4. pmc The impact of different doses of vitamin A supplementation on male and female mortality. A randomised trial from Guinea-Bissau
    Dorthe Yakymenko
    Bandim Health Project, INDEPTH Network, Apartado 861, Bissau, Guinea Bissau
    BMC Pediatr 11:77. 2011
    ..We aimed to test these observations...
  5. pmc Randomised study of effect of different doses of vitamin A on childhood morbidity and mortality
    Christine Stabell Benn
    Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen, Denmark
    BMJ 331:1428-32. 2005
    ..To determine whether the dose of vitamin A currently recommended by the World Health Organization or half this dose gives better protection against childhood morbidity and mortality...
  6. doi request reprint Does vitamin A supplementation interact with routine vaccinations? An analysis of the Ghana Vitamin A Supplementation Trial
    Christine S Benn
    Statens Serum Institut, Copenhagen, Denmark
    Am J Clin Nutr 90:629-39. 2009
    ..However, it is unknown whether the effect of VAS is independent of vaccinations. One of the original VAS trials from Ghana had collected vaccination information...
  7. ncbi request reprint [High-dose vitamin A supplementation decreases childhood mortality rates in low-income countries--can the results be improved?]
    Christine Stabell Benn
    Guinea Bissau Statens Serum Institut, Bandim Health Project, og Københavns Universitet
    Ugeskr Laeger 168:2442-5. 2006
    ..It seems likely that by pursuing these inconsistent observations, vitamin A supplementation programmes can be optimised...
  8. doi request reprint The effect of high-dose vitamin A supplementation administered with BCG vaccine at birth may be modified by subsequent DTP vaccination
    Christine Stabell Benn
    Bandim Health Project, Statens Serum Institut, Copenhagen, Denmark
    Vaccine 27:2891-8. 2009
    ..08 for equal effect of VAS in the two sexes if DTP is the last vaccine). The explanation for the lack of beneficial effect in our setting may have been that VAS at birth interacted negatively with subsequent DTP vaccinations in girls...
  9. ncbi request reprint [Gender differences in response to preventive health care interventions. Do we have to treat girls and boys differently to treat them equally?]
    Christine Stabell Benn
    Bandim Health Project, Statens Serum Institut, København
    Ugeskr Laeger 168:3045-6. 2006
    ..If these observations reflect a general pattern, it may be that, in order to be treated equally, boys and girls should be treated differently...
  10. doi request reprint Should infant girls receive micronutrient supplements?
    Christine Stabell Benn
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    Int J Epidemiol 38:586-90. 2009
    ..Recent zinc/folic acid (FA) and iron supplementation trials did not find any beneficial effects on mortality. We reviewed the studies for evidence of a negative interaction between zinc/folic acid/iron and DTP vaccination in girls...
  11. pmc The effect of vitamin A supplementation administered with missing vaccines during national immunization days in Guinea-Bissau
    Christine Stabell Benn
    Bandim Health Project, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark
    Int J Epidemiol 38:304-11. 2009
    ..We assessed the effect of VAS administered with different vaccines during national immunization days (NIDs)...
  12. pmc Sex-differential effect on infant mortality of oral polio vaccine administered with BCG at birth in Guinea-Bissau. A natural experiment
    Christine Stabell Benn
    Bandim Health Project, Statens Serum Institut, Copenhagen, Denmark
    PLoS ONE 3:e4056. 2008
    ..During a trial of vitamin A supplementation (VAS) at birth in Guinea-Bissau, OPV was not available during several periods. We took advantage of this "natural experiment" to test the effect on mortality of receiving OPV at birth...
  13. pmc Effect of 50,000 IU vitamin A given with BCG vaccine on mortality in infants in Guinea-Bissau: randomised placebo controlled trial
    Christine Stabell Benn
    Bandim Health Project, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark
    BMJ 336:1416-20. 2008
    ..To investigate the effect of high dose vitamin A supplementation given with BCG vaccine at birth in an African setting with high infant mortality...
  14. ncbi request reprint [Cohort study of sibling effect and infectious diseases on the development of atopic dermatitis--secondary publication]
    Christine Stabell Benn
    Statens Serum Institut, Center for Epidemiologisk Grundforskning, Afdeling for Epidemiologisk Forskning, København
    Ugeskr Laeger 167:1754-7. 2005
  15. pmc Vitamin A supplementation and BCG vaccination at birth in low birthweight neonates: two by two factorial randomised controlled trial
    Christine Stabell Benn
    Bandim Health Project, Statens Serum Institut, Copenhagen, Denmark
    BMJ 340:c1101. 2010
    ..To investigate the effect of vitamin A supplementation and BCG vaccination at birth in low birthweight neonates...
  16. ncbi request reprint Thymus size and head circumference at birth and the development of allergic diseases
    C S Benn
    Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, Coenhagen, Denmark
    Clin Exp Allergy 31:1862-6. 2001
    ....
  17. ncbi request reprint Combining vitamin A and vaccines: convenience or conflict?
    Christine Stabell Benn
    Bandim Health Project, Statens Serum Institut, Copenhagen S, Denmark
    Dan Med J 59:B4378. 2012
    ..Only in this way can we assure that the children in the poorest countries get the best possible treatment and avoid using large amounts of money and resources on interventions which may, in worst case, kill them...
  18. ncbi request reprint Sex-differential responses to preventive health interventions. Maybe we treat boys and girls differently when we treat them equally?--Secondary publication
    Christine Stabell Benn
    Bandim Health Project, Statens Serum Institut, 2300 Copenhagen S, Denmark
    Dan Med Bull 54:153-4. 2007
    ....
  19. ncbi request reprint Atopic dermatitis in young children: diagnostic criteria for use in epidemiological studies based on telephone interviews
    Christine Stabell Benn
    Department of Epidemiology Research, Danish Epidemiology, Science Centre, Statens Serum Institut, Copenhagen, Denmark
    Acta Derm Venereol 83:347-50. 2003
    ..Using this algorithm, telephone interviews can be used to diagnose atopic dermatitis in young children in large-scale epidemiological investigations...
  20. ncbi request reprint Mammary epithelial paracellular permeability in atopic and non-atopic mothers versus childhood atopy
    Christine S Benn
    Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen, Denmark
    Pediatr Allergy Immunol 15:123-6. 2004
    ..8 (0.4-1.7), p for interaction = 0.001]. Thus, high Na/K levels in the breast milk may be associated with the development of atopy and atopic diseases in the offspring of atopic mothers...
  21. pmc Cohort study of sibling effect, infectious diseases, and risk of atopic dermatitis during first 18 months of life
    Christine Stabell Benn
    Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, Denmark
    BMJ 328:1223. 2004
    ..To determine whether early infectious diseases could explain the association between number of siblings and other markers of microbial exposure and the development of atopic dermatitis before the age of 18 months...
  22. ncbi request reprint Breastfeeding and risk of atopic dermatitis, by parental history of allergy, during the first 18 months of life
    Christine Stabell Benn
    Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen, Denmark
    Am J Epidemiol 160:217-23. 2004
    ..03). The authors found no overall effects of exclusive or partial breastfeeding on the risk of atopic dermatitis. However, the effect of exclusive breastfeeding for 4 months or more depended on parental history of allergic diseases...
  23. ncbi request reprint DTP with or after measles vaccination is associated with increased in-hospital mortality in Guinea-Bissau
    Peter Aaby
    Projecto de Saude de Bandim, Apartado 861, Bissau, Guinea Bissau
    Vaccine 25:1265-9. 2007
    ..The sequence is not always respected. We examined in-hospital mortality of children having received DTP with or after measles vaccine...
  24. pmc Early diphtheria-tetanus-pertussis vaccination associated with higher female mortality and no difference in male mortality in a cohort of low birthweight children: an observational study within a randomised trial
    Peter Aaby
    Bandim Health Project, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark
    Arch Dis Child 97:685-91. 2012
    ..The authors examined the effect of DTP in a cohort of low birthweight (LBW) infants...
  25. ncbi request reprint Increased female-male mortality ratio associated with inactivated polio and diphtheria-tetanus-pertussis vaccines: Observations from vaccination trials in Guinea-Bissau
    Peter Aaby
    Projecto de Saude de Bandim, INDEPTH Network, Bissau, Guinea Bissau
    Pediatr Infect Dis J 26:247-52. 2007
    ..The 2-fold increase in female mortality after high-titer measles vaccine may have occurred because many children received diphtheria-tetanus-pertussis (DTP) vaccine or inactivated polio vaccine (IPV) after high-titer measles vaccine...
  26. ncbi request reprint Divergent female-male mortality ratios associated with different routine vaccinations among female-male twin pairs
    Peter Aaby
    Bandim Health Project, Apartado 861, Bissau, Guinea Bissau
    Int J Epidemiol 33:367-73. 2004
    ..As background information, we examined sex- and age-specific mortality patterns in the pre-vaccination era. Subjects In all, 626 female-male twin pairs identified between 1978 and 2000...
  27. doi request reprint The effect of high-dose vitamin A supplementation given with bacille Calmette-Guérin vaccine at birth on infant rotavirus infection and diarrhea: a randomized prospective study from Guinea-Bissau
    Birgitte Rode Diness
    Bandim Health Project, INDEPTH Network, Guinea Bissau
    J Infect Dis 202:S243-51. 2010
    ..Prophylactic vitamin A supplementation (VAS) reduces mortality and may reduce morbidity associated with diarrhea in children >6 months of age. Rotavirus is the most common cause of acute dehydrating diarrhea among children worldwide...
  28. ncbi request reprint Survival bias in observational studies of the impact of routine immunizations on childhood survival
    Henrik Jensen
    Bandim Health Project, Danish Epidemiology Science Centre and Statens Serum Institut, Copenhagen, Denmark
    Trop Med Int Health 12:5-14. 2007
    ..We examined whether this could be because of methodological differences...
  29. ncbi request reprint DTP vaccination and child survival in observational studies with incomplete vaccination data
    Peter Aaby
    Bandim Health Project, Danish Epidemiology Science Centre and Statens Serum Institut, Bissau, Guinea Bissau, Denmark
    Trop Med Int Health 12:15-24. 2007
    ..None of these studies had complete information on DTP vaccinations from both survivors and children who died. We reviewed the data analysis methodology to assess whether methodological differences could explain the divergent results...
  30. doi request reprint Smallpox vaccination and all-cause infectious disease hospitalization: a Danish register-based cohort study
    Signe Sørup
    Bandim Health Project, Statens Serum Institut, Copenhagen, Denmark
    Int J Epidemiol 40:955-63. 2011
    ..In Denmark, the live vaccine against smallpox was phased out in the 1970s due to the eradication of smallpox. We used the phasing-out period to investigate the effect of smallpox vaccination on the risk of hospitalization for infections...
  31. doi request reprint The immunological effect of revaccination with Bacille Calmette-Guérin vaccine at 19 months of age
    Andreas Andersen
    Research Center for Vitamins and Vaccines, Bandim Health Project, Statens Serum Institute, Artillerivej 5, 2300 Copenhagen S, Denmark
    Vaccine 31:2137-44. 2013
    ..Within the trial we assessed the immunological effects of BCG revaccination...
  32. pmc Effect of revaccination with BCG in early childhood on mortality: randomised trial in Guinea-Bissau
    Adam Edvin Roth
    Bandim Health Project, INDEPTH Network, Apartado 861, Bissau, Guinea Bissau
    BMJ 340:c671. 2010
    ..To determine whether BCG revaccination at 19 months of age reduces overall child mortality...
  33. doi request reprint Randomized trial of BCG vaccination at birth to low-birth-weight children: beneficial nonspecific effects in the neonatal period?
    Peter Aaby
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    J Infect Dis 204:245-52. 2011
    ..Low-birth-weight (LBW) children are not given BCG at birth in Guinea-Bissau; we conducted a randomized trial of BCG at birth (early BCG) vs delayed BCG...
  34. doi request reprint High-dose vitamin A supplementation administered with vaccinations after 6 months of age: sex-differential adverse reactions and morbidity
    Ane Bærent Fisker
    Bandim Health Project, INDEPTH Network, Apartado 861, Bissau, Guinea Bissau
    Vaccine 31:3191-8. 2013
    ..WHO recommends vitamin A supplementation (VAS) at vaccination contacts after six months of age. The effect of this recommendation on mortality has not been evaluated...
  35. doi request reprint Risk of inflammatory bowel disease following Bacille Calmette-Guérin and smallpox vaccination: a population-based Danish case-cohort study
    Marie Villumsen
    Research Center for Vitamins and Vaccines CVIVA, Bandim Health Project, Statens Serum Institut, Copenhagen, Denmark
    Inflamm Bowel Dis 19:1717-24. 2013
    ....
  36. pmc Determinants of vitamin a deficiency in children between 6 months and 2 years of age in Guinea-Bissau
    Niels Danneskiold-Samsøe
    Research Center for Vitamins and Vaccines, Bandim Health Project, Statens Serum Institut, Orestads Boulevard, Copenhagen S 2300, Denmark
    BMC Public Health 13:172. 2013
    ..To date, no national survey has been conducted. We assessed vitamin A status among children in rural Guinea-Bissau to assess status and identify risk factors for VAD...
  37. ncbi request reprint Hypothesis: Vitamin A supplementation and childhood mortality: amplification of the non-specific effects of vaccines?
    Christine Stabell Benn
    Projecto de Saude de Bandim, Bissau, Guinea Bissau
    Int J Epidemiol 32:822-8. 2003
    ..We propose that the effect of vitamin A supplementation may depend on the amplification of non-specific effects of vaccines on childhood mortality...
  38. doi request reprint Clustering of acute respiratory infection hospitalizations in childcare facilities
    Mads Kamper-Jørgensen
    Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark
    Acta Paediatr 99:877-82. 2010
    ..To estimate how risk of acute respiratory infection (ARI) hospitalization in children attending childcare facilities with a recently (within 1 month) hospitalized child is affected by gender, age and other characteristics...
  39. ncbi request reprint Atopic disposition, wheezing, and subsequent respiratory syncytial virus hospitalization in Danish children younger than 18 months: a nested case-control study
    Lone Graff Stensballe
    Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen, Denmark
    Pediatrics 118:e1360-8. 2006
    ..This study examined whether atopic disposition, wheezing, and atopic disorders increased the risk of hospitalizations because of respiratory syncytial virus in children between birth and 18 months of age...
  40. doi request reprint Maternal obesity, gestational weight gain, and risk of asthma and atopic disease in offspring: a study within the Danish National Birth Cohort
    Maria C Harpsøe
    Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark
    J Allergy Clin Immunol 131:1033-40. 2013
    ..High pre-pregnancy body mass index (BMI) and excessive gestational weight gain (GWG) are suggested to influence risk of asthma and atopic disease in offspring...
  41. ncbi request reprint Vaccinia scars associated with better survival for adults. An observational study from Guinea-Bissau
    Peter Aaby
    Projecto de Saude de Bandim, Apartado 861, Bissau, Guinea Bissau, Denmark
    Vaccine 24:5718-25. 2006
    ..Live vaccines including BCG and measles may have non-targeted beneficial effects on childhood survival in areas with high mortality. The authors therefore undertook a survey of vaccinia scars to evaluate subsequent mortality...
  42. doi request reprint No effect of oral polio vaccine administered at birth on mortality and immune response to BCG. A natural experiment
    Najaaraq Lund
    Research Center for Vitamins and Vaccines CVIVA, Bandim Health Project, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark
    Vaccine 30:6694-9. 2012
    ..In 2007, whilst conducting a trial of BCG and vitamin A supplementation (VAS) at birth to low birthweight (LBW) children, OPV was again lacking for a short period. We used this natural experiment to test the previous observations...
  43. doi request reprint Small randomized trial among low-birth-weight children receiving bacillus Calmette-Guérin vaccination at first health center contact
    Sofie Biering-Sørensen
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    Pediatr Infect Dis J 31:306-8. 2012
    ..28 (0.06-1.37) in the first month, and 0.27 (0.07-0.98) after 2 months of age. The mortality rate ratio was 0.41 (0.14-1.18) (P = 0.098) in infancy. Administration of BCG vaccine at first contact may contribute to lower mortality...
  44. ncbi request reprint Sex differential effects of routine immunizations and childhood survival in rural Malawi
    Peter Aaby
    Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen, Denmark
    Pediatr Infect Dis J 25:721-7. 2006
    ..Recent studies from West Africa suggest that routine vaccinations may have sex differential nontargeted effects. To answer whether these patterns are found elsewhere, we reanalyzed data about vaccinations and mortality in a Malawian cohort...
  45. ncbi request reprint Mode of delivery and risk of allergic rhinitis and asthma
    Peter Bager
    Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen, Denmark
    J Allergy Clin Immunol 111:51-6. 2003
    ..Furthermore, it has been suggested that complicated modes of delivery might be associated with an increased risk of asthma...
  46. pmc Vitamin A supplementation at birth might prime the response to subsequent vitamin A supplements in girls. Three year follow-up of a randomized trial
    Ane Bærent Fisker
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    PLoS ONE 6:e23265. 2011
    ..We conducted a post-hoc analysis to test the hypothesis that neonatal VAS primes the response to subsequent vitamin A...
  47. ncbi request reprint Long-term consequences of respiratory syncytial virus acute lower respiratory tract infection in early childhood in Guinea-bissau
    Anja Poulsen
    Projecto de Saude de Bandim, Guinea Bissau, Copenhagen, Denmark
    Pediatr Infect Dis J 25:1025-31. 2006
    ..The study aimed to investigate long-term consequences of respiratory syncytial virus (RSV) positive acute lower respiratory tract infection (ALRI) in a low-income country according to severity of the initial infection...
  48. ncbi request reprint Oral polio vaccination and low case fatality at the paediatric ward in Bissau, Guinea-Bissau
    Peter Aaby
    Bandim Health Project, Apartado 861, Bissau, Guinea Bissau
    Vaccine 22:3014-7. 2004
    ..Control for background factors had no impact on the estimate. In areas with high mortality, OPV administered alone may have non-specific beneficial effects or DTP may have a negative effect for children who had received both DTP and OPV...
  49. ncbi request reprint A randomized trial of an early measles vaccine at 4½ months of age in Guinea-bissau: sex-differential immunological effects
    Kristoffer Jarlov Jensen
    Research Center for Vitamins and Vaccines CVIVA, Bandim Health Project, Statens Serum Institut, Copenhagen, Denmark Department of Cardiovascular and Renal Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    PLoS ONE 9:e97536. 2014
    ..After measles vaccine (MV), all-cause mortality is reduced more than can be explained by the prevention of measles, especially in females...
  50. doi request reprint The effect of early measles vaccination on thymic size. A randomized study from Guinea-Bissau
    Lone Damkjær Christensen
    Faculty of Health Sciences, University of Southern Denmark, Denmark Electronic address
    Vaccine 32:1641-4. 2014
    ..In conclusion, early MV at age 4.5 months had no overall effect on thymus size 4 weeks later. Trial registration: http://clinicaltrials.gov, NCT01486355. ..
  51. pmc A prospective study of twinning and perinatal mortality in urban Guinea-Bissau
    Morten Bjerregaard-Andersen
    Bandim Health Project, INDEPTH Network, Apartado 861, 1004, Bissau Codex, Guinea Bissau
    BMC Pregnancy Childbirth 12:140. 2012
    ..Despite twinning being common in Africa, few prospective twin studies have been conducted. We studied twinning rate, perinatal mortality and the clinical characteristics of newborn twins in urban Guinea-Bissau...
  52. doi request reprint SNP may modify the effect of vitamin A supplementation at birth on cytokine production in a whole blood culture assay
    Mathias Jul Jørgensen
    Bandim Health Project, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark
    Br J Nutr 107:615-20. 2012
    ..Although the present study had very limited representation of the genetic variation with potential for modification of the response to VAS, it adds to the efforts of untangling the diverse effects and impact of VAS...
  53. pmc The Effect of 50 000 IU Vitamin A with BCG Vaccine at Birth on Growth in the First Year of Life
    Ane Bærent Fisker
    Bandim Health Project, INDEPTH Network, Apartado 861, 1004 Bissau, Guinea Bissau
    J Trop Med 2011:570170. 2011
    ..The VAS effect differed significantly between the BCG and DTP windows (P = 0.03), and the difference was borderline significant between the DTP and MV windows for girls (P = 0.09)...
  54. ncbi request reprint Population-based study of the impact of childcare attendance on hospitalizations for acute respiratory infections
    Mads Kamper-Jørgensen
    Department of Epidemiology Research, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark
    Pediatrics 118:1439-46. 2006
    ....
  55. ncbi request reprint Does oral polio vaccine at birth affect the size of the thymus? Observations within a randomized trial
    Helle Brander Eriksen
    Research Center for Vitamins and Vaccines CVIVA, Statens Serum Institut, Artillerivej 5, 2300 København S, Denmark Department of Clinical Microbiology, Copenhagen University Hospital, Hvidovre, Kettegårds Alle 30, 2650 Hvidovre, Denmark Electronic address
    Vaccine 32:3293-9. 2014
    ..We therefore initiated a randomized trial to test the overall effect of OPV at birth (OPV0)...
  56. ncbi request reprint Co-administration of live measles and yellow fever vaccines and inactivated pentavalent vaccines is associated with increased mortality compared with measles and yellow fever vaccines only. An observational study from Guinea-Bissau
    Ane Bærent Fisker
    Bandim Health Project, INDEPTH Network, Apartado 861, Bissau, Guinea Bissau Research Center for Vitamins and Vaccines CVIVA, Bandim Health Project, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark Electronic address
    Vaccine 32:598-605. 2014
    ..Pentavalent and YF vaccines were introduced in Guinea-Bissau in 2008. We investigated whether co-administration of pentavalent vaccine with MV and yellow fever vaccine has similar negative effects...
  57. ncbi request reprint Maternal vaginal microflora during pregnancy and the risk of asthma hospitalization and use of antiasthma medication in early childhood
    Christine Stabell Benn
    Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen, Denmark
    J Allergy Clin Immunol 110:72-7. 2002
    ..It is therefore conceivable that the maternal vaginal microflora might influence the establishment of the infant flora and, as a consequence, the development of wheezing and allergic diseases...
  58. doi request reprint The effect of vitamin A supplementation and diphtheria-tetanus-pertussis vaccination on parasitaemia in an experimental murine malaria model
    Mathias Jul Jørgensen
    Bandim Health Project, INDEPTH Network, Statens Serum Institut, Copenhagen, Denmark
    Scand J Infect Dis 43:296-303. 2011
    ..The immunological effects of combining the 2 treatments are unknown...
  59. ncbi request reprint BCG vaccination among West African infants is associated with less anergy to tuberculin and diphtheria-tetanus antigens
    M L Garly
    Projecto de Saude de Bandim, Apartado 861, Bissau, Guinea Bissau
    Vaccine 20:468-74. 2001
    ..BCG vaccination and a positive tuberculin reaction were associated with a lower prevalence of anergy to both tuberculin and diphtheria-tetanus. Thus, BCG vaccination may contribute to better cell-mediated immune responses among infants...
  60. ncbi request reprint Measles antibody responses after early two dose trials in Guinea-Bissau with Edmonston-Zagreb and Schwarz standard-titre measles vaccine: better antibody increase from booster dose of the Edmonston-Zagreb vaccine
    M L Garly
    Projecto de Saude de Bandim, Apartado 861, 1004, Bissau Codex, Guinea Bissau
    Vaccine 19:1951-9. 2001
    ..The EZ vaccine was less sensitive to maternal antibodies, and able to increase the antibody response by revaccination, while the second SW vaccine resulted in an unchanged or lower antibody response...
  61. pmc Vitamin A supplementation and risk of atopy: long-term follow-up of a randomized trial of vitamin A supplementation at six and nine months of age
    Nicholas Kiraly
    Bandim Health Project, INDEPTH Network, Apartado 861, Bissau, Guinea Bissau
    BMC Pediatr 13:190. 2013
    ..VAS has been associated with up-regulation of the Th2 response. We aimed to determine if VAS is associated with atopy in childhood...
  62. pmc A comparison of ex vivo cytokine production in venous and capillary blood
    M Eriksson
    Projecto de Saude de Bandim, INDEPTH Network, Bissau, Guinea Bissau
    Clin Exp Immunol 150:469-76. 2007
    ..We found significant differences in the production of cytokines between venous and capillary blood. Such differences should be taken into account when setting up immuno-epidemiological studies...
  63. ncbi request reprint Reduced case fatality among hospitalized children during a war in Guinea-Bissau: a lesson in equity
    M Sodemann
    Projecto de Saude Bandim, Guinea Bissau
    Acta Paediatr 93:959-64. 2004
    ..During a recent armed conflict in Guinea-Bissau, we observed a marked decline in the case fatality among hospitalized children at the only paediatric department in the country...