Research Topics
Genomes and Genes | Sylwia OwczarekSummaryCountry: Denmark Publications
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Publications
Neuroplastin-55 binds to and signals through the fibroblast growth factor receptorSylwia Owczarek
Protein Laboratory, Department of Neuroscience and Pharmacology, Panum Institute, University of Copenhagen, Blegdamsvej 3C, Bldg 24 2, 2200 Copenhagen, Denmark
FASEB J 24:1139-50. 2010..Owczarek, S., Kiryushko, D., Larsen, M. H., Kastrup, J. S., Gajhede, M., Sandi, C., Berezin, V., Bock, E., Soroka, V. Neuroplastin-55 binds to and signals through the fibroblast growth factor receptor...
Neuroplastin-65 and a mimetic peptide derived from its homophilic binding site modulate neuritogenesis and neuronal plasticitySylwia Owczarek
The Protein Laboratory, Department of Neuroscience and Pharmacology, University of Copenhagen, Denmark
J Neurochem 117:984-94. 2011..In addition, we show that interference with Np65 homophilic binding by enplastin has an inhibitory effect on Np65-mediated neurite outgrowth in vitro and on the initial phase of spatial learning in rats...
Neuroplastin: cell adhesion molecule and signaling receptorSylwia Owczarek
The Protein Laboratory, Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark
Int J Biochem Cell Biol 44:1-5. 2012..Here, we will review the Np structure and mechanisms involved in Np signaling and discuss the functions of Nps in the nervous system...
Peptides derived from the solvent-exposed loops 3 and 4 of BDNF bind TrkB and p75(NTR) receptors and stimulate neurite outgrowth and survivalKristina Fobian
Protein Laboratory, Department of Neuroscience and Pharmacology, Faculty of Health Sciences, University of Copenhagen, Denmark
J Neurosci Res 88:1170-81. 2010..Thus, two peptides derived from BDNF induced neurite outgrowth and enhanced neuronal survival, probably through binding to BDNF receptors...
Multiple effects of pentyl-4-yn-VPA enantiomers: from toxicity to short-term memory enhancementKamil Gotfryd
Protein Laboratory, Institute of Molecular Pathology, Panum Institute, University of Copenhagen, Blegdamsvej 3C Bld 6 2, DK 2200 Copenhagen N, Denmark
Neuropharmacology 52:764-78. 2007....
NCAM-derived peptides function as agonists for the fibroblast growth factor receptorStine M M Hansen
Protein Laboratory, Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark
J Neurochem 106:2030-41. 2008....
Relative role of upstream regulators of Akt, ERK and CREB in NCAM- and FGF2-mediated signallingDorte Kornerup Ditlevsen
Protein Laboratory, Department of Neuroscience and Pharmacology, University of Copenhagen, Panum Institute, Building 6 2, Blegdamsvej 3, DK 2200 Copenhagen, Denmark
Neurochem Int 53:137-47. 2008....
The metastasis-promoting S100A4 protein confers neuroprotection in brain injuryOksana Dmytriyeva
Protein Laboratory, Panum Institute, Blegdamsvej 3C, Building 24 2, Copenhagen 2200N, Denmark
Nat Commun 3:1197. 2012..Our data introduce S100A4 as a therapeutic target in neurodegeneration, and raise the entire S100 family as a potentially important factor in central nervous system injury...
