Vibe Skov

Summary

Affiliation: Odense University Hospital
Country: Denmark

Publications

  1. doi request reprint Gene expression profiling with principal component analysis depicts the biological continuum from essential thrombocythemia over polycythemia vera to myelofibrosis
    Vibe Skov
    Department of Clinical Genetics, Odense University Hospital, Odense, Denmark
    Exp Hematol 40:771-780.e19. 2012
  2. ncbi request reprint Reduced expression of nuclear-encoded genes involved in mitochondrial oxidative metabolism in skeletal muscle of insulin-resistant women with polycystic ovary syndrome
    Vibe Skov
    Department of Biochemistry, Genetics, and Pharmacology, Odense University Hospital and Human Microarray Centre, University of Southern Denmark, Odense, Denmark
    Diabetes 56:2349-55. 2007
  3. pmc Pioglitazone enhances mitochondrial biogenesis and ribosomal protein biosynthesis in skeletal muscle in polycystic ovary syndrome
    Vibe Skov
    Department of Biochemistry, Genetics, and Pharmacology, Odense University Hospital and Human Microarray Centre, University of Southern Denmark, Odense, Denmark
    PLoS ONE 3:e2466. 2008
  4. pmc Global gene expression profiling displays a network of dysregulated genes in non-atherosclerotic arterial tissue from patients with type 2 diabetes
    Vibe Skov
    Department of Clinical Biochemistry and Pharmacology, Odense University Hospital, Odense, Denmark
    Cardiovasc Diabetol 11:15. 2012
  5. doi request reprint Molecular profiling of peripheral blood cells from patients with polycythemia vera and related neoplasms: identification of deregulated genes of significance for inflammation and immune surveillance
    Vibe Skov
    Department of Clinical Genetics, Odense University Hospital, Odense, Denmark
    Leuk Res 36:1387-92. 2012
  6. doi request reprint Whole-blood transcriptional profiling of interferon-inducible genes identifies highly upregulated IFI27 in primary myelofibrosis
    Vibe Skov
    Department of Clinical Genetics, Odense University Hospital, Odense, Denmark
    Eur J Haematol 87:54-60. 2011
  7. doi request reprint Increased gene expression of histone deacetylases in patients with Philadelphia-negative chronic myeloproliferative neoplasms
    Vibe Skov
    Department of Clinical Genetics, Odense University Hospital, Denmark
    Leuk Lymphoma 53:123-9. 2012
  8. pmc Insulin resistance is not conserved in myotubes established from women with PCOS
    Mette Eriksen
    Department of Endocrinology, Odense University Hospital, Odense, Denmark
    PLoS ONE 5:e14469. 2010
  9. ncbi request reprint Spotting and validation of a genome wide oligonucleotide chip with duplicate measurement of each gene
    Mads Thomassen
    Department of Biochemistry, Pharmacology, and Genetics, Odense University Hospital and Human Microarray Centre, University of Southern Denmark, Odense, Denmark
    Biochem Biophys Res Commun 344:1111-20. 2006
  10. doi request reprint No influence of OPG and its ligands, RANKL and TRAIL, on proliferation and regulation of the calcification process in primary human vascular smooth muscle cells
    Malene Olesen
    Department of Cardiovascular and Renal Research, Institute of Molecular Medicine, University of Southern Denmark, Denmark
    Mol Cell Endocrinol 362:149-56. 2012

Collaborators

Detail Information

Publications11

  1. doi request reprint Gene expression profiling with principal component analysis depicts the biological continuum from essential thrombocythemia over polycythemia vera to myelofibrosis
    Vibe Skov
    Department of Clinical Genetics, Odense University Hospital, Odense, Denmark
    Exp Hematol 40:771-780.e19. 2012
    ..Functional analysis suggests an important implication of these gene ontology clusters in the pathogenesis of these neoplasms and in disease evolution from ET over PV to PMF...
  2. ncbi request reprint Reduced expression of nuclear-encoded genes involved in mitochondrial oxidative metabolism in skeletal muscle of insulin-resistant women with polycystic ovary syndrome
    Vibe Skov
    Department of Biochemistry, Genetics, and Pharmacology, Odense University Hospital and Human Microarray Centre, University of Southern Denmark, Odense, Denmark
    Diabetes 56:2349-55. 2007
    ..These abnormalities may contribute to the increased risk of type 2 diabetes observed in women with PCOS...
  3. pmc Pioglitazone enhances mitochondrial biogenesis and ribosomal protein biosynthesis in skeletal muscle in polycystic ovary syndrome
    Vibe Skov
    Department of Biochemistry, Genetics, and Pharmacology, Odense University Hospital and Human Microarray Centre, University of Southern Denmark, Odense, Denmark
    PLoS ONE 3:e2466. 2008
    ..These transcriptional effects of pioglitazone may contribute to prevent the onset of type 2 diabetes in these women...
  4. pmc Global gene expression profiling displays a network of dysregulated genes in non-atherosclerotic arterial tissue from patients with type 2 diabetes
    Vibe Skov
    Department of Clinical Biochemistry and Pharmacology, Odense University Hospital, Odense, Denmark
    Cardiovasc Diabetol 11:15. 2012
    ..These changes may render the vessel wall more susceptible to injury; however, the molecular characteristics of such diffuse pre-atherosclerotic changes in diabetes are only superficially known...
  5. doi request reprint Molecular profiling of peripheral blood cells from patients with polycythemia vera and related neoplasms: identification of deregulated genes of significance for inflammation and immune surveillance
    Vibe Skov
    Department of Clinical Genetics, Odense University Hospital, Odense, Denmark
    Leuk Res 36:1387-92. 2012
    ..Our findings may reflect chronic inflammation to be of pathogenetic importance for the progression of these neoplasms toward the myelofibrotic end-stage and may also account for the increased frequency of second cancer in these diseases...
  6. doi request reprint Whole-blood transcriptional profiling of interferon-inducible genes identifies highly upregulated IFI27 in primary myelofibrosis
    Vibe Skov
    Department of Clinical Genetics, Odense University Hospital, Odense, Denmark
    Eur J Haematol 87:54-60. 2011
    ..Finally, IFI27 may be a novel biomarker of disease activity and tumor burden in patients with CMPNs...
  7. doi request reprint Increased gene expression of histone deacetylases in patients with Philadelphia-negative chronic myeloproliferative neoplasms
    Vibe Skov
    Department of Clinical Genetics, Odense University Hospital, Denmark
    Leuk Lymphoma 53:123-9. 2012
    ....
  8. pmc Insulin resistance is not conserved in myotubes established from women with PCOS
    Mette Eriksen
    Department of Endocrinology, Odense University Hospital, Odense, Denmark
    PLoS ONE 5:e14469. 2010
    ....
  9. ncbi request reprint Spotting and validation of a genome wide oligonucleotide chip with duplicate measurement of each gene
    Mads Thomassen
    Department of Biochemistry, Pharmacology, and Genetics, Odense University Hospital and Human Microarray Centre, University of Southern Denmark, Odense, Denmark
    Biochem Biophys Res Commun 344:1111-20. 2006
    ..6%. Relative quantitation was more reproducible than absolute quantitation and substantial reduction of variance was attained with duplicate spotting. An analysis of variance (ANOVA) demonstrated no significant day-to-day variation...
  10. doi request reprint No influence of OPG and its ligands, RANKL and TRAIL, on proliferation and regulation of the calcification process in primary human vascular smooth muscle cells
    Malene Olesen
    Department of Cardiovascular and Renal Research, Institute of Molecular Medicine, University of Southern Denmark, Denmark
    Mol Cell Endocrinol 362:149-56. 2012
    ..However, overall RANKL and/or insulin did not affect the development of calcification of HVSMCs. These studies indicate that OPG knockdown does not alter the calcification process in HVSMCs...
  11. doi request reprint Fibulin-1 is a marker for arterial extracellular matrix alterations in type 2 diabetes
    Claudia Cangemi
    Department of Clinical Biochemistry and Pharmacology, Institute of Molecular Medicine and Clinical Institute, Odense University Hospital, University of Southern Denmark
    Clin Chem 57:1556-65. 2011
    ..However, no biomarkers for diabetes-related arterial changes have been defined...