Søren H Sindrup

Summary

Affiliation: Odense University Hospital
Country: Denmark

Publications

  1. ncbi request reprint The NK1-receptor antagonist TKA731 in painful diabetic neuropathy: a randomised, controlled trial
    Søren H Sindrup
    Department of Neurology, Odense University Hospital, Denmark
    Eur J Pain 10:567-71. 2006
  2. ncbi request reprint [Pharmacological treatment of neuropathic pain]
    Søren H Sindrup
    Neurologisk afdeling, Odense Universitetshospital, DK 5000 Odense C
    Tidsskr Nor Laegeforen 124:637-8. 2004
  3. ncbi request reprint Antidepressants in the treatment of neuropathic pain
    Søren H Sindrup
    Department of Neurology, Odense University Hospital, DK 5000 Odense, Denmark
    Basic Clin Pharmacol Toxicol 96:399-409. 2005
  4. ncbi request reprint Health-related quality of life and its predictive role for analgesic effect in patients with painful polyneuropathy
    Marit Otto
    Department of Neurology, Odense University Hospital, DK 5000 Odense C, Denmark
    Eur J Pain 11:572-8. 2007
  5. doi request reprint The anticonvulsant levetiracetam for the treatment of pain in polyneuropathy: a randomized, placebo-controlled, cross-over trial
    Jakob V Holbech
    Department of Neurology, Odense University Hospital, Denmark
    Eur J Pain 15:608-14. 2011
  6. doi request reprint Escitalopram in painful polyneuropathy: a randomized, placebo-controlled, cross-over trial
    Marit Otto
    Department of Neurology, Odense University Hospital, University of Southern Denmark, Sdr Boulevard 29, Odense C, Denmark
    Pain 139:275-83. 2008
  7. ncbi request reprint Valproic acid has no effect on pain in polyneuropathy: a randomized, controlled trial
    Marit Otto
    Department of Neurology, Odense University Hospital, Denmark
    Neurology 62:285-8. 2004
  8. ncbi request reprint Chronic neuropathic pain: mechanisms, drug targets and measurement
    Nanna B Finnerup
    Department of Neurology, Danish Pain Research Center, Aarhus University Hospital, DK 8000 Aarhus, Denmark
    Fundam Clin Pharmacol 21:129-36. 2007
  9. ncbi request reprint Pain phenomena and possible mechanisms in patients with painful polyneuropathy
    Marit Otto
    Department of Neurology, Odense University, Odense Universitetshospital, Neurologisk afdeling, Sdr Boulevard 29, DK 5000, Odense C, Denmark
    Pain 101:187-92. 2003
  10. pmc An evidence-based algorithm for the treatment of neuropathic pain
    Nanna B Finnerup
    Department of Neurology, Danish Pain Research Center, Aarhus University Hospital, Aarhus, Denmark
    MedGenMed 9:36. 2007

Detail Information

Publications13

  1. ncbi request reprint The NK1-receptor antagonist TKA731 in painful diabetic neuropathy: a randomised, controlled trial
    Søren H Sindrup
    Department of Neurology, Odense University Hospital, Denmark
    Eur J Pain 10:567-71. 2006
    ..4 mm vs. -11.6 mm, p = 0.664) nor for change in ratings of different pain symptoms (touch- or pressure-evoked pain, pain paroxysms, steady burning or deep aching pain) (p = 0.169-0.834)...
  2. ncbi request reprint [Pharmacological treatment of neuropathic pain]
    Søren H Sindrup
    Neurologisk afdeling, Odense Universitetshospital, DK 5000 Odense C
    Tidsskr Nor Laegeforen 124:637-8. 2004
  3. ncbi request reprint Antidepressants in the treatment of neuropathic pain
    Søren H Sindrup
    Department of Neurology, Odense University Hospital, DK 5000 Odense, Denmark
    Basic Clin Pharmacol Toxicol 96:399-409. 2005
    ..However, without head-to-head comparisons between antidepressants and other analgesics, it is not possible to provide real evidence-based treatment algorithms for neuropathic pain...
  4. ncbi request reprint Health-related quality of life and its predictive role for analgesic effect in patients with painful polyneuropathy
    Marit Otto
    Department of Neurology, Odense University Hospital, DK 5000 Odense C, Denmark
    Eur J Pain 11:572-8. 2007
    ..Results show an impaired HRQL in painful polyneuropathy and suggest that HRQL may predict response to analgesic treatment...
  5. doi request reprint The anticonvulsant levetiracetam for the treatment of pain in polyneuropathy: a randomized, placebo-controlled, cross-over trial
    Jakob V Holbech
    Department of Neurology, Odense University Hospital, Denmark
    Eur J Pain 15:608-14. 2011
    ..This could have an impact on signaling in the nociceptive system, and a pilot study indicated relief of neuropathic pain with levetiracetam...
  6. doi request reprint Escitalopram in painful polyneuropathy: a randomized, placebo-controlled, cross-over trial
    Marit Otto
    Department of Neurology, Odense University Hospital, University of Southern Denmark, Sdr Boulevard 29, Odense C, Denmark
    Pain 139:275-83. 2008
    ..Currently, the drug cannot be recommended as a standard treatment in neuropathic pain...
  7. ncbi request reprint Valproic acid has no effect on pain in polyneuropathy: a randomized, controlled trial
    Marit Otto
    Department of Neurology, Odense University Hospital, Denmark
    Neurology 62:285-8. 2004
    ..There was no significant difference between valproic acid and placebo in the rating of total pain (median, 5 in the valproic acid period vs 6 in the placebo period; p = 0.24) or in individual pain ratings...
  8. ncbi request reprint Chronic neuropathic pain: mechanisms, drug targets and measurement
    Nanna B Finnerup
    Department of Neurology, Danish Pain Research Center, Aarhus University Hospital, DK 8000 Aarhus, Denmark
    Fundam Clin Pharmacol 21:129-36. 2007
    ..The present review summarizes mechanisms of neuropathic pain, targets of currently used drugs, and measures used in neuropathic pain trials...
  9. ncbi request reprint Pain phenomena and possible mechanisms in patients with painful polyneuropathy
    Marit Otto
    Department of Neurology, Odense University, Odense Universitetshospital, Neurologisk afdeling, Sdr Boulevard 29, DK 5000, Odense C, Denmark
    Pain 101:187-92. 2003
    ..sensitized small fibers as the single mechanism of pain is rare; and (4). pain symptomatology cannot predict pain mechanisms as being mainly deafferentation or sensitized small fibers...
  10. pmc An evidence-based algorithm for the treatment of neuropathic pain
    Nanna B Finnerup
    Department of Neurology, Danish Pain Research Center, Aarhus University Hospital, Aarhus, Denmark
    MedGenMed 9:36. 2007
    ..The purpose of this article is to discuss an evidence-based algorithm that can be implemented by the primary care physician in his/her daily clinical practice for the treatment of patients with neuropathic pain conditions...
  11. ncbi request reprint Specific effect of levetiracetam in experimental human pain models
    Thomas P Enggaard
    Institute of Public Health, Clinical Pharmacology, University of Southern Denmark, Odense University, Winslowparken 19, DK 5000 Odense C, Denmark
    Eur J Pain 10:193-8. 2006
    ..Levetiracetam is a new antiepileptic drug. There is only limited experience with levetiracetam in clinical neuropathic pain...
  12. doi request reprint A candidate gene study of serotonergic pathway genes and pain relief during treatment with escitalopram in patients with neuropathic pain shows significant association to serotonin receptor2C (HTR2C)
    Charlotte Brasch-Andersen
    Department of Clinical Biochemistry and Pharmacology, Odense University Hospital, Odense, Denmark
    Eur J Clin Pharmacol 67:1131-7. 2011
    ..The aim of this study was to investigate the association between polymorphisms in genes involved in the serotonergic pathway and the effect of escitalopram on peripheral neuropathic pain...
  13. ncbi request reprint Pharmacotherapy of trigeminal neuralgia
    Søren H Sindrup
    Department of Neurology, Odense and Aarhus University Hospitals, Denmark
    Clin J Pain 18:22-7. 2002
    ..Controlled trials testing the effect of some of these drugs, new drugs, and drug combinations are needed...