Camilla H Sandholt

Summary

Affiliation: Novo Nordisk A/S
Country: Denmark

Publications

  1. pmc Non-replication of genome-wide based associations between common variants in INSIG2 and PFKP and obesity in studies of 18,014 Danes
    Camilla H Andreasen
    Steno Diabetes Center, Copenhagen, Denmark
    PLoS ONE 3:e2872. 2008
  2. ncbi Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation
    Camilla H Andreasen
    Steno Diabetes Center, Niels Steensens Vej 1, NLC2 13, DK 2820 Gentofte, Denmark
    Diabetes 57:95-101. 2008
  3. pmc Combined analyses of 20 common obesity susceptibility variants
    Camilla Helene Sandholt
    Hagedorn Research Institute, Gentofte, Denmark
    Diabetes 59:1667-73. 2010
  4. pmc Studies of metabolic phenotypic correlates of 15 obesity associated gene variants
    Camilla Helene Sandholt
    The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
    PLoS ONE 6:e23531. 2011
  5. pmc Lack of association between PKLR rs3020781 and NOS1AP rs7538490 and type 2 diabetes, overweight, obesity and related metabolic phenotypes in a Danish large-scale study: case-control studies and analyses of quantitative traits
    Camilla Helene Andreasen
    Steno Diabetes Center, 2820 Gentofte, Denmark
    BMC Med Genet 9:118. 2008
  6. pmc Studies of CTNNBL1 and FDFT1 variants and measures of obesity: analyses of quantitative traits and case-control studies in 18,014 Danes
    Camilla Helene Andreasen
    Steno Diabetes Center, Gentofte, Denmark
    BMC Med Genet 10:17. 2009
  7. pmc Bioinformatics-driven identification and examination of candidate genes for non-alcoholic fatty liver disease
    Karina Banasik
    Hagedorn Research Institute, Gentofte, Denmark
    PLoS ONE 6:e16542. 2011
  8. pmc Implications of central obesity-related variants in LYPLAL1, NRXN3, MSRA, and TFAP2B on quantitative metabolic traits in adult Danes
    Dorthe S Bille
    The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
    PLoS ONE 6:e20640. 2011
  9. ncbi Genetic susceptibility to type 2 diabetes and obesity: from genome-wide association studies to rare variants and beyond
    Niels Grarup
    The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, DIKU Building, Universitetsparken 1, 2100, Copenhagen Ø, Denmark
    Diabetologia 57:1528-41. 2014
  10. pmc Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
    Niels Grarup
    The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
    PLoS Genet 9:e1003530. 2013

Collaborators

Detail Information

Publications11

  1. pmc Non-replication of genome-wide based associations between common variants in INSIG2 and PFKP and obesity in studies of 18,014 Danes
    Camilla H Andreasen
    Steno Diabetes Center, Copenhagen, Denmark
    PLoS ONE 3:e2872. 2008
    ..We focused on physical activity as an environmental risk factor, and on the GWA identified obesity variants in FTO (rs9939609) and near MC4R (rs17782313) as genetic risk factors...
  2. ncbi Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation
    Camilla H Andreasen
    Steno Diabetes Center, Niels Steensens Vej 1, NLC2 13, DK 2820 Gentofte, Denmark
    Diabetes 57:95-101. 2008
    ..In the present study, the effect of FTO variation on metabolic traits including obesity, type 2 diabetes, and related quantitative phenotypes was examined...
  3. pmc Combined analyses of 20 common obesity susceptibility variants
    Camilla Helene Sandholt
    Hagedorn Research Institute, Gentofte, Denmark
    Diabetes 59:1667-73. 2010
    ..Genome-wide association studies and linkage studies have identified 20 validated genetic variants associated with obesity and/or related phenotypes. The variants are common, and they individually exhibit small-to-modest effect sizes...
  4. pmc Studies of metabolic phenotypic correlates of 15 obesity associated gene variants
    Camilla Helene Sandholt
    The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
    PLoS ONE 6:e23531. 2011
    ..Moreover, we want to investigate if these loci associate with type 2 diabetes and to elucidate potential underlying metabolic mechanisms...
  5. pmc Lack of association between PKLR rs3020781 and NOS1AP rs7538490 and type 2 diabetes, overweight, obesity and related metabolic phenotypes in a Danish large-scale study: case-control studies and analyses of quantitative traits
    Camilla Helene Andreasen
    Steno Diabetes Center, 2820 Gentofte, Denmark
    BMC Med Genet 9:118. 2008
    ..Further, we intended to expand the analyses by examining the effect of the variants in relation to overweight and obesity...
  6. pmc Studies of CTNNBL1 and FDFT1 variants and measures of obesity: analyses of quantitative traits and case-control studies in 18,014 Danes
    Camilla Helene Andreasen
    Steno Diabetes Center, Gentofte, Denmark
    BMC Med Genet 10:17. 2009
    ..The aim of this study was to investigate the impact of these three variants on obesity, through analyses of obesity-related quantitative traits, and case-control studies in large study samples of Danes...
  7. pmc Bioinformatics-driven identification and examination of candidate genes for non-alcoholic fatty liver disease
    Karina Banasik
    Hagedorn Research Institute, Gentofte, Denmark
    PLoS ONE 6:e16542. 2011
    ..Candidate genes for non-alcoholic fatty liver disease (NAFLD) identified by a bioinformatics approach were examined for variant associations to quantitative traits of NAFLD-related phenotypes...
  8. pmc Implications of central obesity-related variants in LYPLAL1, NRXN3, MSRA, and TFAP2B on quantitative metabolic traits in adult Danes
    Dorthe S Bille
    The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
    PLoS ONE 6:e20640. 2011
    ....
  9. ncbi Genetic susceptibility to type 2 diabetes and obesity: from genome-wide association studies to rare variants and beyond
    Niels Grarup
    The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, DIKU Building, Universitetsparken 1, 2100, Copenhagen Ø, Denmark
    Diabetologia 57:1528-41. 2014
    ..Here we review recent progress as regards the concepts, methodologies and derived outcomes of studies of the genetics of type 2 diabetes and obesity, and discuss avenues to be investigated in the future within this research field. ..
  10. pmc Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
    Niels Grarup
    The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
    PLoS Genet 9:e1003530. 2013
    ..Yet, the study demonstrates the value of combining whole genome and exome sequencing approaches to ascertain the genetic and molecular architectures underlying quantitative trait associations...
  11. pmc The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load
    Malene Hornbak
    Marie Krogh Center for Metabolic Research, Section of Metabolic Genetics, Faculty of Health Sciences, University of Copenhagen, Denmark
    BMC Med Genet 12:4. 2011
    ..We aimed to investigate whether the two variants associate with altered insulin release following an oral glucose load or with T2D...