P Kurtzhals

Summary

Affiliation: Novo Nordisk
Country: Denmark

Publications

  1. ncbi request reprint Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use
    P Kurtzhals
    Health Care Discovery, Novo Nordisk, Bagsvaerd, Denmark
    Diabetes 49:999-1005. 2000
  2. ncbi request reprint Secretory expression of human albumin domains in Saccharomyces cerevisiae and their binding of myristic acid and an acylated insulin analogue
    T Kjeldsen
    Novo Nordisk, Bagsvaerd, DK 2880, Denmark
    Protein Expr Purif 13:163-9. 1998
  3. doi request reprint Insulin X10 revisited: a super-mitogenic insulin analogue
    B F Hansen
    Novo Nordisk A S, Bagsvaerd, Denmark
    Diabetologia 54:2226-31. 2011
  4. ncbi request reprint How to achieve a predictable basal insulin?
    P Kurtzhals
    Novo Nordisk, Bagsvaerd, Copenhagen, Denmark
    Diabetes Metab 31:4S25-4S33. 2005
  5. ncbi request reprint Engineering predictability and protraction in a basal insulin analogue: the pharmacology of insulin detemir
    P Kurtzhals
    Novo Nordisk, Bagsvaerd, Denmark
    Int J Obes Relat Metab Disord 28:S23-8. 2004

Detail Information

Publications5

  1. ncbi request reprint Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use
    P Kurtzhals
    Health Care Discovery, Novo Nordisk, Bagsvaerd, Denmark
    Diabetes 49:999-1005. 2000
    ..The reduced in vitro potency of insulin detemir might explain why this analog is not as effective on a molar basis as human insulin in humans...
  2. ncbi request reprint Secretory expression of human albumin domains in Saccharomyces cerevisiae and their binding of myristic acid and an acylated insulin analogue
    T Kjeldsen
    Novo Nordisk, Bagsvaerd, DK 2880, Denmark
    Protein Expr Purif 13:163-9. 1998
    ..A new soluble long-acting insulin an alogue acylated with myristic acid (Markussen J., et al., Diabetologia 39, 281-288, 1996) bound to domain III and bound markedly more weakly to domain I...
  3. doi request reprint Insulin X10 revisited: a super-mitogenic insulin analogue
    B F Hansen
    Novo Nordisk A S, Bagsvaerd, Denmark
    Diabetologia 54:2226-31. 2011
    ....
  4. ncbi request reprint How to achieve a predictable basal insulin?
    P Kurtzhals
    Novo Nordisk, Bagsvaerd, Copenhagen, Denmark
    Diabetes Metab 31:4S25-4S33. 2005
    ..Taken together, insulin detemir provides an attractive novel approach for predictive basal insulin delivery to people with diabetes...
  5. ncbi request reprint Engineering predictability and protraction in a basal insulin analogue: the pharmacology of insulin detemir
    P Kurtzhals
    Novo Nordisk, Bagsvaerd, Denmark
    Int J Obes Relat Metab Disord 28:S23-8. 2004
    ..Thus, insulin detemir offers the promise of an improved tolerability:efficacy ratio in the clinical setting...