P Kurtzhals

Summary

Affiliation: Novo Nordisk
Country: Denmark

Publications

  1. ncbi Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use
    P Kurtzhals
    Health Care Discovery, Novo Nordisk, Bagsvaerd, Denmark
    Diabetes 49:999-1005. 2000
  2. ncbi Secretory expression of human albumin domains in Saccharomyces cerevisiae and their binding of myristic acid and an acylated insulin analogue
    T Kjeldsen
    Novo Nordisk, Bagsvaerd, DK 2880, Denmark
    Protein Expr Purif 13:163-9. 1998
  3. ncbi Insulin X10 revisited: a super-mitogenic insulin analogue
    B F Hansen
    Novo Nordisk A S, Bagsvaerd, Denmark
    Diabetologia 54:2226-31. 2011
  4. ncbi How to achieve a predictable basal insulin?
    P Kurtzhals
    Novo Nordisk, Bagsvaerd, Copenhagen, Denmark
    Diabetes Metab 31:4S25-4S33. 2005
  5. ncbi Engineering predictability and protraction in a basal insulin analogue: the pharmacology of insulin detemir
    P Kurtzhals
    Novo Nordisk, Bagsvaerd, Denmark
    Int J Obes Relat Metab Disord 28:S23-8. 2004

Detail Information

Publications5

  1. ncbi Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use
    P Kurtzhals
    Health Care Discovery, Novo Nordisk, Bagsvaerd, Denmark
    Diabetes 49:999-1005. 2000
    ..The reduced in vitro potency of insulin detemir might explain why this analog is not as effective on a molar basis as human insulin in humans...
  2. ncbi Secretory expression of human albumin domains in Saccharomyces cerevisiae and their binding of myristic acid and an acylated insulin analogue
    T Kjeldsen
    Novo Nordisk, Bagsvaerd, DK 2880, Denmark
    Protein Expr Purif 13:163-9. 1998
    ..A new soluble long-acting insulin an alogue acylated with myristic acid (Markussen J., et al., Diabetologia 39, 281-288, 1996) bound to domain III and bound markedly more weakly to domain I...
  3. ncbi Insulin X10 revisited: a super-mitogenic insulin analogue
    B F Hansen
    Novo Nordisk A S, Bagsvaerd, Denmark
    Diabetologia 54:2226-31. 2011
    ....
  4. ncbi How to achieve a predictable basal insulin?
    P Kurtzhals
    Novo Nordisk, Bagsvaerd, Copenhagen, Denmark
    Diabetes Metab 31:4S25-4S33. 2005
    ..Taken together, insulin detemir provides an attractive novel approach for predictive basal insulin delivery to people with diabetes...
  5. ncbi Engineering predictability and protraction in a basal insulin analogue: the pharmacology of insulin detemir
    P Kurtzhals
    Novo Nordisk, Bagsvaerd, Denmark
    Int J Obes Relat Metab Disord 28:S23-8. 2004
    ..Thus, insulin detemir offers the promise of an improved tolerability:efficacy ratio in the clinical setting...