Hal Blumberg

Summary

Affiliation: Novo Nordisk A/S
Country: Denmark

Publications

  1. doi request reprint IL-1RL2 and its ligands contribute to the cytokine network in psoriasis
    Hal Blumberg
    Amgen, Seattle, WA 98119, USA
    J Immunol 185:4354-62. 2010
  2. pmc Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation
    Hal Blumberg
    Department of Inflammation, 2Department of Pathology, 3Department of Biostatistics, Amgen, Seattle, WA 98119, USA
    J Exp Med 204:2603-14. 2007
  3. doi request reprint RIP4 regulates epidermal differentiation and cutaneous inflammation
    Ryan B Rountree
    Department of Oncology, Amgen, Seattle, Washington, USA
    J Invest Dermatol 130:102-12. 2010
  4. pmc RANK overexpression in transgenic mice with mouse mammary tumor virus promoter-controlled RANK increases proliferation and impairs alveolar differentiation in the mammary epithelia and disrupts lumen formation in cultured epithelial acini
    Eva Gonzalez-Suarez
    Department of Cancer Biology, AW2 D2262, Amgen Inc, 1201 Amgen Court West, Seattle, WA 98119, USA
    Mol Cell Biol 27:1442-54. 2007

Collaborators

Detail Information

Publications4

  1. doi request reprint IL-1RL2 and its ligands contribute to the cytokine network in psoriasis
    Hal Blumberg
    Amgen, Seattle, WA 98119, USA
    J Immunol 185:4354-62. 2010
    ..Blockade of IL-1F6 receptor also resolves the inflammatory changes in human psoriatic lesional skin transplanted onto immunodeficient mice. These data suggest a role for IL-1F family members in psoriasis...
  2. pmc Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation
    Hal Blumberg
    Department of Inflammation, 2Department of Pathology, 3Department of Biostatistics, Amgen, Seattle, WA 98119, USA
    J Exp Med 204:2603-14. 2007
    ..In summary, dysregulated expression of novel agonistic and antagonistic IL-1 family member ligands can promote cutaneous inflammation, revealing potential novel targets for the treatment of inflammatory skin disorders...
  3. doi request reprint RIP4 regulates epidermal differentiation and cutaneous inflammation
    Ryan B Rountree
    Department of Oncology, Amgen, Seattle, Washington, USA
    J Invest Dermatol 130:102-12. 2010
    ..These data suggest that RIP4 functions in the epidermis through PKC-specific signaling pathways to regulate differentiation and inflammation...
  4. pmc RANK overexpression in transgenic mice with mouse mammary tumor virus promoter-controlled RANK increases proliferation and impairs alveolar differentiation in the mammary epithelia and disrupts lumen formation in cultured epithelial acini
    Eva Gonzalez-Suarez
    Department of Cancer Biology, AW2 D2262, Amgen Inc, 1201 Amgen Court West, Seattle, WA 98119, USA
    Mol Cell Biol 27:1442-54. 2007
    ..Moreover, the increased proliferation and survival observed in a three-dimensional culture system suggests a role for aberrant RANK signaling during breast tumorigenesis...